New York Knicks vs Philadelphia 76ers Prediction, Picks & Odds | NBA Wednesday

NBA Betting Preview: Knicks vs Sixers

The New York Knicks go head-to-head with the Philadelphia 76ers in this NBA contest. Our betting preview features expert NBA predictions, betting tips, the latest odds, H2H stats, player stats, team news and confirmed starting lineups.

With the Knicks being given a line of +2.5 to overcome, our betting prediction is that they can cover this against the Sixers. There’s the opportunity to get -112 for this outcome.

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New York Knicks lost when they last took to the court. At Madison Square Garden, they were turned over 137-134 (OT) at home to Indiana Pacers. Jalen Brunson poured in 40 points, with Mikal Bridges contributing 22 and Karl-Anthony Towns adding 22.

Philadelphia 76ers have enjoyed three straight home wins. In their last game, they lost on the road to Portland Trail Blazers 135-118 at Moda Center. Tyrese Maxey scored 30 points, while Kelly Oubre Jr. finished with 19 and Justin Edwards 12.

Head-to-Head Statistics

It was a 112-109 win for the Knicks at Xfinity Mobile Arena when they last played the Sixers. The Knicks have triumphed in seven of the previous 10 clashes between these teams.

NBA	W	L	PCT	PPG	OPP PPG	DIFF	Home	Road	Div	Conf	Last 10	Strk
Knicks	34	20	0.63	117.6	112.3	5.3	21-7	13-13	9-3	23-13	8-2	1L
76ers	30	23	0.566	116.7	115.5	1.2	15-13	15-10	8-5	19-17	6-4	1L

View Full Standings

8 wins and 2 losses in the past 10 games. The Knicks are averaging 116.4 points, 46.5 rebounds, 28.2 assists, 7.0 steals and 3.1 blocks while shooting 47.5% from the field and 76.2% from the free-throw line. The opposition average 105.7 points and 42.1 rebounds per contest.

Jalen Brunson is averaging 25.6 points, 6.3 assists and 3.1 (34.8%) 3-pointers made, while Karl-Anthony Towns averages 12.3 rebounds.

The Sixers have won 6 and lost 4 of their previous 10 contests. Averaging 116.1 points, 40.0 rebounds, 25.6 assists, 9.0 steals and 4.0 blocks per game while shooting 48.4% from the field and 81.8% from the free-throw line. Their opponents have an average of 115.3 points and 43.8 rebounds.

Tyrese Maxey is averaging 23.6 points, 7.0 assists and 2.7 (32.5%) 3-pointers made, while Valdez Edgecombe has an average of 5.7 rebounds.

New York Knicks vs Philadelphia 76ers Prediction & Picks

The New York Knicks vs Philadelphia 76ers betting tips feature sharp analysis across major markets, including a key match prediction, correct score guidance and a ready-made bet builder.

Game Prediction

Considering the +2.5 that is on offer for Knicks, our pick is that the underdogs will cover the spread in this NBA contest. They can stay in the game and odds of -112 is available.

Our basketball picks are always well-researched, starting with a combination of the latest NBA team news and current form. Once we’ve got a solid read on the matchup, we layer in the key data to back it up.

Key Knicks vs 76ers stats:

• The +2.5 line has been covered by Knicks in 8 of their last 10 games.
• The +2.5 line has been covered by Knicks in 4 of their last 5 games on the road.
• The -2.5 line hasn’t been covered by Sixers in 12 of their last 20 games at home.
• The -2.5 line hasn’t been covered by Sixers in 7 of their last 10 games against Knicks.

Knicks +2.5 Probability

According to the best NBA sportsbooks, our pick has a 52.9% chance of delivering a return. After careful examination, our analysts calculate this probability to be closer to 60%. This is why we can recommend this wager.

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Our Game Prediction

Knicks +2.5 @ -112 Bet Now

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Correct Score Prediction

Knicks 115 - 112 76ers

For a fun wager, consider backing the Knicks to claim a 115-112 victory. Although it’s a speculative bet, we are expecting things to be close between the two teams.

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New York Knicks vs Philadelphia 76ers Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

We’re seeing Philadelphia 76ers priced up at -143 for a victory, with New York Knicks trading at +120. There is a 59% chance of the hosts winning according to the top NBA sportsbooks.

The current spread is 2.5 and total points is 221.5. Having a bet on the Totals is one of the most popular basketball wagers. If you’re wanting to back Over 221.5, the odds are -112.

The good news is that you can access a huge selection of game lines and team props for most contests. The top basketball betting sites have a massive range of pre-game and in-game wagering options.

Moneyline

Knicks

+120

76ers

-143

Point Spread

Knicks +2.5

-112

76ers -2.5

-108

Total Points

Under 221.5

-108

Over 221.5

-112

There is regularly betting value to be found from wagering on the player props with the best online gambling sites. You can find lots of ways to back for or against a specific player lining up for one of the two teams.

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The Sixers have secured three straight wins at Xfinity Mobile Arena. They are 6-4 in their last 10 home games, putting up 118.90 points per contest and giving up 116.10.

The Knicks have five wins and five losses in the last 10 games away from home, averaging 108.80 points scored and 109.40 points allowed.

The Knicks earned a 112-109 win against the Sixers in the teams’ last meeting at Xfinity Mobile Arena. In their past 10 head-to-head matchups at Xfinity Mobile Arena, the Knicks have recorded seven victories, while the Sixers have managed three.

Last 10 Games		W-L	P	PF	PA	O221.5	U221.5
Philadelphia 76ers Home Stats		6-4	235.00	118.90	116.10	8	2
New York Knicks Away Stats		5-5	218.20	108.80	109.40	3	7

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O221.5 = Games Over 221.5 Points
• U221.5 = Games Under 221.5 Points

Latest regular season and playoff games stats.

New York Knicks Stats

Philadelphia 76ers Stats

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 games on the road

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 home games

Point Spread

• +2.5 Betting Line: Have covered the spread in 8 of the last 10 games
• +2.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• -2.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -2.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games

Total Points

• Game Totals: An average of 222.10 pts in the previous 10 games
• Game Totals on the Road: An average of 218.20 pts in the previous 10 games on the road
• Over 221.5: Covered in 4 of the previous 10 games
• Over 221.5 on the Road: Covered in 3 of the previous 10 games on the road
• Team Totals: Have scored an average of 116.40 pts and allowed 105.70 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 108.80 pts and allowed 109.40 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 231.40 pts in the previous 10 games
• Game Totals at Home: An average of 235.00 pts in the previous 10 home games
• Over 221.5: Covered in 7 of the previous 10 games
• Over 221.5 at Home: Covered in 8 of the previous 10 home games
• Team Totals: Have scored an average of 116.10 pts and allowed 115.30 pts in the last 10 games
• Team Totals at Home: Have scored an average of 118.90 pts and allowed 116.10 pts in the last 10 home games

Team Stats - Avg/Game

Last 10 Games

• 2-Pointers Made: 28.00 (56%)
• 3-Pointers Made: 15.00 (37%)
• Free Throws Made: 15.40 (76.24%)
• Rebounds: Total 46.5, Offensive 11.70, Defensive 34.80
• Assists: 28.20
• Blocks: 3.10
• Steals: 7.00
• Turnovers : 11.70
• Personal Fouls: 20.20

Last 10 Games on the Road

• 2-Pointers Made: 26.60 (53%)
• 3-Pointers Made: 13.60 (36%)
• Free Throws Made: 14.80 (74.75%)
• Rebounds: Total 44.3, Offensive 12.20, Defensive 32.10
• Assists: 25.80
• Blocks: 3.80
• Steals: 7.00
• Turnovers : 12.40
• Personal Fouls: 19.30

Team Stats - Avg/Game

Last 10 Games

• 2-Pointers Made: 29.40 (55%)
• 3-Pointers Made: 12.20 (38%)
• Free Throws Made: 20.70 (81.82%)
• Rebounds: Total 40, Offensive 10.90, Defensive 29.10
• Assists: 25.60
• Blocks: 4.00
• Steals: 9.00
• Turnovers : 11.50
• Personal Fouls: 19.70

Last 10 Home Games

• 2-Pointers Made: 30.90 (56%)
• 3-Pointers Made: 12.10 (37%)
• Free Throws Made: 20.80 (80%)
• Rebounds: Total 40.7, Offensive 10.80, Defensive 29.90
• Assists: 27.50
• Blocks: 4.90
• Steals: 10.50
• Turnovers : 11.10
• Personal Fouls: 17.90

Injuries & Suspensions

Starting Lineups

Both teams’ confirmed lineups will be published ahead of tip-off. There is also the chance to look at the lineups from the previous 10 games.

NBA Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Division Conference League

East Atlantic	W	L	PCT	PPG	OPP PPG	DIFF	Home	Road	Div	Conf	Last 10	Strk
Knicks	34	20	0.63	117.6	112.3	5.3	21-7	13-13	9-3	23-13	8-2	1L
Celtics	34	19	0.642	115.1	108.4	6.7	17-9	17-10	7-5	23-13	7-3	1L
Raptors	32	22	0.593	114.1	112.2	1.9	16-12	16-10	4-9	24-14	7-3	2W
76ers	30	23	0.566	116.7	115.5	1.2	15-13	15-10	8-5	19-17	6-4	1L
Nets	15	37	0.288	107.6	114.9	-7.3	8-18	7-19	3-9	11-21	3-7	2W

East Central	W	L	PCT	PPG	OPP PPG	DIFF	Home	Road	Div	Conf	Last 10	Strk
Pistons	39	13	0.75	117.3	109.6	7.7	22-6	17-7	8-3	25-7	7-3	2W
Cavaliers	33	21	0.611	119.6	115.9	3.7	17-11	16-10	7-3	19-13	9-1	4W
Bulls	24	30	0.444	117	120.6	-3.6	15-12	9-18	3-9	16-21	2-8	5L
Bucks	21	30	0.412	111.7	115.8	-4.1	12-12	9-18	7-4	16-18	4-6	1L
Pacers	14	40	0.259	111.1	118.8	-7.7	10-18	4-22	3-9	10-26	4-6	1W

East Southeast	W	L	PCT	PPG	OPP PPG	DIFF	Home	Road	Div	Conf	Last 10	Strk
Magic	28	24	0.538	115.2	115.2	0	18-9	10-15	6-5	19-17	5-5	3W
Heat	28	27	0.509	119.5	117.3	2.2	16-11	12-16	4-5	15-16	5-5	1L
Hawks	26	29	0.473	117.5	118.8	-1.3	10-15	16-14	5-4	13-19	6-4	2L
Hornets	25	29	0.463	115.8	113.9	1.9	11-14	14-15	7-4	15-20	9-1	1L
Wizards	14	38	0.269	112.1	122.8	-10.7	9-18	5-20	2-6	9-22	4-6	2L

West Northwest	W	L	PCT	PPG	OPP PPG	DIFF	Home	Road	Div	Conf	Last 10	Strk
Thunder	41	13	0.759	119.9	108	11.9	22-6	19-7	8-3	31-9	5-5	1W
Nuggets	34	20	0.63	120.3	116.4	3.9	14-11	20-9	4-2	19-9	5-5	1L
Timberwolves	33	22	0.6	119.4	114.9	4.5	18-10	15-12	5-5	18-17	6-4	1W
Trail Blazers	26	28	0.481	116.1	118	-1.9	16-13	10-15	4-4	20-15	4-6	3W
Jazz	17	37	0.315	118.2	126.4	-8.2	10-17	7-20	1-8	9-24	2-8	1W

West Pacific	W	L	PCT	PPG	OPP PPG	DIFF	Home	Road	Div	Conf	Last 10	Strk
Lakers	32	21	0.604	115.9	116.3	-0.4	14-10	18-11	5-6	21-14	6-4	2L
Suns	32	22	0.593	113.7	111.4	2.3	18-9	14-13	8-6	22-15	5-5	1W
Warriors	29	25	0.537	115.6	113.5	2.1	18-9	11-16	6-4	19-15	4-6	1W
Clippers	25	28	0.472	112	112.5	-0.5	13-11	12-17	7-4	15-16	6-4	1L
Kings	12	43	0.218	110.5	120.6	-10.1	9-19	3-24	2-8	8-28	0-10	13L

West Southwest	W	L	PCT	PPG	OPP PPG	DIFF	Home	Road	Div	Conf	Last 10	Strk
Spurs	37	16	0.698	118	112.2	5.8	19-6	18-10	10-3	23-13	7-3	5W
Rockets	33	19	0.635	114.9	109.7	5.2	18-6	15-13	6-5	19-15	7-3	2W
Grizzlies	20	32	0.385	115.3	117.4	-2.1	11-15	9-17	5-6	16-20	2-8	3L
Mavericks	19	34	0.358	114.1	117.3	-3.2	14-16	5-18	3-9	11-24	2-8	8L
Pelicans	15	40	0.273	114.7	120.4	-5.7	9-19	6-21	6-7	9-26	5-5	2W

Eastern Conference	W	L	PCT	PPG	OPP PPG	DIFF	Home	Road	Div	Conf	Last 10	Strk
Pistons	39	13	0.75	117.3	109.6	7.7	22-6	17-7	8-3	25-7	7-3	2W
Celtics	34	19	0.642	115.1	108.4	6.7	17-9	17-10	7-5	23-13	7-3	1L
Knicks	34	20	0.63	117.6	112.3	5.3	21-7	13-13	9-3	23-13	8-2	1L
Cavaliers	33	21	0.611	119.6	115.9	3.7	17-11	16-10	7-3	19-13	9-1	4W
Raptors	32	22	0.593	114.1	112.2	1.9	16-12	16-10	4-9	24-14	7-3	2W
76ers	30	23	0.566	116.7	115.5	1.2	15-13	15-10	8-5	19-17	6-4	1L
Magic	28	24	0.538	115.2	115.2	0	18-9	10-15	6-5	19-17	5-5	3W
Heat	28	27	0.509	119.5	117.3	2.2	16-11	12-16	4-5	15-16	5-5	1L
Hawks	26	29	0.473	117.5	118.8	-1.3	10-15	16-14	5-4	13-19	6-4	2L
Hornets	25	29	0.463	115.8	113.9	1.9	11-14	14-15	7-4	15-20	9-1	1L
Bulls	24	30	0.444	117	120.6	-3.6	15-12	9-18	3-9	16-21	2-8	5L
Bucks	21	30	0.412	111.7	115.8	-4.1	12-12	9-18	7-4	16-18	4-6	1L
Nets	15	37	0.288	107.6	114.9	-7.3	8-18	7-19	3-9	11-21	3-7	2W
Wizards	14	38	0.269	112.1	122.8	-10.7	9-18	5-20	2-6	9-22	4-6	2L
Pacers	14	40	0.259	111.1	118.8	-7.7	10-18	4-22	3-9	10-26	4-6	1W

Western Conference	W	L	PCT	PPG	OPP PPG	DIFF	Home	Road	Div	Conf	Last 10	Strk
Thunder	41	13	0.759	119.9	108	11.9	22-6	19-7	8-3	31-9	5-5	1W
Spurs	37	16	0.698	118	112.2	5.8	19-6	18-10	10-3	23-13	7-3	5W
Nuggets	34	20	0.63	120.3	116.4	3.9	14-11	20-9	4-2	19-9	5-5	1L
Rockets	33	19	0.635	114.9	109.7	5.2	18-6	15-13	6-5	19-15	7-3	2W
Lakers	32	21	0.604	115.9	116.3	-0.4	14-10	18-11	5-6	21-14	6-4	2L
Timberwolves	33	22	0.6	119.4	114.9	4.5	18-10	15-12	5-5	18-17	6-4	1W
Suns	32	22	0.593	113.7	111.4	2.3	18-9	14-13	8-6	22-15	5-5	1W
Warriors	29	25	0.537	115.6	113.5	2.1	18-9	11-16	6-4	19-15	4-6	1W
Trail Blazers	26	28	0.481	116.1	118	-1.9	16-13	10-15	4-4	20-15	4-6	3W
Clippers	25	28	0.472	112	112.5	-0.5	13-11	12-17	7-4	15-16	6-4	1L
Grizzlies	20	32	0.385	115.3	117.4	-2.1	11-15	9-17	5-6	16-20	2-8	3L
Mavericks	19	34	0.358	114.1	117.3	-3.2	14-16	5-18	3-9	11-24	2-8	8L
Jazz	17	37	0.315	118.2	126.4	-8.2	10-17	7-20	1-8	9-24	2-8	1W
Pelicans	15	40	0.273	114.7	120.4	-5.7	9-19	6-21	6-7	9-26	5-5	2W
Kings	12	43	0.218	110.5	120.6	-10.1	9-19	3-24	2-8	8-28	0-10	13L

NBA	W	L	PCT	PPG	OPP PPG	DIFF	Home	Road	Div	Conf	Last 10	Strk
Thunder	41	13	0.759	119.9	108	11.9	22-6	19-7	8-3	31-9	5-5	1W
Pistons	39	13	0.75	117.3	109.6	7.7	22-6	17-7	8-3	25-7	7-3	2W
Spurs	37	16	0.698	118	112.2	5.8	19-6	18-10	10-3	23-13	7-3	5W
Celtics	34	19	0.642	115.1	108.4	6.7	17-9	17-10	7-5	23-13	7-3	1L
Rockets	33	19	0.635	114.9	109.7	5.2	18-6	15-13	6-5	19-15	7-3	2W
Nuggets	34	20	0.63	120.3	116.4	3.9	14-11	20-9	4-2	19-9	5-5	1L
Knicks	34	20	0.63	117.6	112.3	5.3	21-7	13-13	9-3	23-13	8-2	1L
Cavaliers	33	21	0.611	119.6	115.9	3.7	17-11	16-10	7-3	19-13	9-1	4W
Lakers	32	21	0.604	115.9	116.3	-0.4	14-10	18-11	5-6	21-14	6-4	2L
Timberwolves	33	22	0.6	119.4	114.9	4.5	18-10	15-12	5-5	18-17	6-4	1W
Suns	32	22	0.593	113.7	111.4	2.3	18-9	14-13	8-6	22-15	5-5	1W
Raptors	32	22	0.593	114.1	112.2	1.9	16-12	16-10	4-9	24-14	7-3	2W
76ers	30	23	0.566	116.7	115.5	1.2	15-13	15-10	8-5	19-17	6-4	1L
Magic	28	24	0.538	115.2	115.2	0	18-9	10-15	6-5	19-17	5-5	3W
Warriors	29	25	0.537	115.6	113.5	2.1	18-9	11-16	6-4	19-15	4-6	1W
Heat	28	27	0.509	119.5	117.3	2.2	16-11	12-16	4-5	15-16	5-5	1L
Trail Blazers	26	28	0.481	116.1	118	-1.9	16-13	10-15	4-4	20-15	4-6	3W
Hawks	26	29	0.473	117.5	118.8	-1.3	10-15	16-14	5-4	13-19	6-4	2L
Clippers	25	28	0.472	112	112.5	-0.5	13-11	12-17	7-4	15-16	6-4	1L
Hornets	25	29	0.463	115.8	113.9	1.9	11-14	14-15	7-4	15-20	9-1	1L
Bulls	24	30	0.444	117	120.6	-3.6	15-12	9-18	3-9	16-21	2-8	5L
Bucks	21	30	0.412	111.7	115.8	-4.1	12-12	9-18	7-4	16-18	4-6	1L
Grizzlies	20	32	0.385	115.3	117.4	-2.1	11-15	9-17	5-6	16-20	2-8	3L
Mavericks	19	34	0.358	114.1	117.3	-3.2	14-16	5-18	3-9	11-24	2-8	8L
Jazz	17	37	0.315	118.2	126.4	-8.2	10-17	7-20	1-8	9-24	2-8	1W
Nets	15	37	0.288	107.6	114.9	-7.3	8-18	7-19	3-9	11-21	3-7	2W
Pelicans	15	40	0.273	114.7	120.4	-5.7	9-19	6-21	6-7	9-26	5-5	2W
Wizards	14	38	0.269	112.1	122.8	-10.7	9-18	5-20	2-6	9-22	4-6	2L
Pacers	14	40	0.259	111.1	118.8	-7.7	10-18	4-22	3-9	10-26	4-6	1W
Kings	12	43	0.218	110.5	120.6	-10.1	9-19	3-24	2-8	8-28	0-10	13L

• W = Wins
• L = Losses
• PCT = Winning Percentage
• PPG = Points Per Game
• OPP PPG = Opponent Points Per Game
• DIFF = Average Point Differential
• Home = Home Record
• Road = Away Record
• Div = Division Record
• Conf = Conference Record
• Last 10 = Record last 10 games
• Strk = Current Streak

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