Ohio vs Louisville Prediction, Picks & Odds | 15 Nov 2025

College Basketball Betting Preview: Ohio vs Louisville

The Ohio Bobcats square off against the Louisville Cardinals, with tip-off scheduled for 13:00 on Saturday, November 15.

There’s every chance that the total won’t be as high as 174.5, so we’re prepared to take the -110 that Ohio and Louisville go under the line.

Ohio Bobcats suffered a defeat in their previous game. A 90-60 scoreline occurred on the road against Saint Mary's Gaels.

Louisville Cardinals were winners last time out. It was a 96-88 home victory against Kentucky Wildcats.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Louisville	23-9	2724	2304	420	16-2	7-7	3W
Ohio	15-16	2417	2429	-12	11-8	4-8	3L

View Full Standings

Ohio vs Louisville Prediction & Picks

Step into Ohio vs Louisville with confidence, armed with our expert match prediction, likely scoreline, key player prop plays and a custom-built bet builder for maximum value.

Game Prediction

In our opinion, the teams are unlikely to reach the 174.5 points line. Therefore, chance an Under wager at -110 and hope the number isn’t reached in this college matchup.

We use the latest team news and injury updates to help shape the best possible basketball predictions. You’ll also notice we take a stats-led approach by factoring in the key college hoops numbers that truly make a difference.

Key Ohio vs Louisville stats:

• The 174.5 line hasn’t been covered in 17 of the last 20 Ohio games.
• The 174.5 line hasn’t been covered in 8 of the last 10 Ohio games.
• The 174.5 line hasn’t been covered in the last 3 Ohio games.
• The 174.5 line hasn’t been covered in 18 of the last 20 Louisville games.
• The 174.5 line hasn’t been covered in 8 of the last 10 Louisville games.

Under 174.5 Probability

According to the latest betting odds, our pick has a 52.4% chance of winning. In our opinion, there’s actually a probability of success closer to 60%. This college basketball wager can therefore be backed with confidence.

If you’re wanting bigger odds for your Under wager, then there’s a way of changing the line and shooting for a lower points total in the hope of a better return.

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Our Game Prediction

Under 174.5 Points @ -110 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Nov 14, 21:06). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Mikel Brown Jr. Over 5.5 Assists +120

Mikel Brown Jr. (Louisville) can be wagered to rack up Over 5.5 assists at +120. We think it makes sense to stick with him when it comes to Overs and bettors can be confident with this Player Assists pick.

Latest Mikel Brown Jr. Player Prop Odds

Points

Over 16.5

-125

Under 16.5

-105

Assists

Over 5.5

+120

Under 5.5

-154

Rebounds

Over 3.5

+130

Under 3.5

-175

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Ryan Conwell Under 1.5 Assists -125

Ryan Conwell (Louisville) can be wagered to finish with Under 1.5 assists at -125. There are a number of reasons that suggest he will fall short of the Player Assists line, making this an appealing wager.

Latest Ryan Conwell Player Prop Odds

Points

Over 14.5

-118

Under 14.5

-110

Assists

Over 1.5

-105

Under 1.5

-125

Rebounds

Over 3.5

+130

Under 3.5

-164

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Ohio 67 - 102 Louisville

There are some big returns lying in wait if you can get the correct score right. With this in mind, we’ll have a play on Louisville to enjoy a 102-67 winning scoreline.

T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Ohio vs Louisville Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The sportsbooks make this game uncompetitive, with Louisville expected to comfortably win. Therefore, the Moneyline might not be available and it’s better to instead play the spread to assess the various options.

The spread is 31.5 and the total points line is currently 175.5. Basketball fans regularly enjoy the opportunity to bet on the Totals. If you fancy Under 175.5, then the odds are -110.

There are stacks of game lines and team props s when it comes to wagering on college basketball and we recommend visiting the top betting apps to find the bet that matches your view on the contest.

Moneyline

Ohio

-

Louisville

-

Point Spread

Ohio +31.5

-104

Louisville -31.5

-118

Total Points

Under 175.5

-110

Over 175.5

-110

In terms of hitting the most buckets, favorite Mikel Brown Jr. is available at -125 to rack up Over 16.5 points. If you want to go Under, then -105 is available.

Mikel Brown Jr. (Louisville)

Over 16.5

-125

Under 16.5

-105

Ryan Conwell (Louisville)

Over 14.5

-118

Under 14.5

-110

Isaac McKneely (Louisville)

Over 9.5

-130

Under 9.5

-100

Mikel Brown Jr. (Louisville)

Over 5.5

+120

Under 5.5

-154

Ryan Conwell (Louisville)

Over 1.5

-105

Under 1.5

-125

Isaac McKneely (Louisville)

Over 1.5

-100

Under 1.5

-130

Mikel Brown Jr. (Louisville)

Over 3.5

+130

Under 3.5

-175

Ryan Conwell (Louisville)

Over 3.5

+130

Under 3.5

-164

Isaac McKneely (Louisville)

Over 2.5

-149

Under 2.5

+115

Micro betting is something that’s really popular with bettors, with college basketball fans essentially being able to wager in-game when it comes to score, player and team props. Check out the two-way lines where you can bet whether the next shot will be a Two-pointer or a Three-pointer.

Latest regular season and playoff games stats.

Ohio Stats

Louisville Stats

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 9 wins and 1 defeat in the last 10 home games

Point Spread

• +30.5 Betting Line: Have covered the spread in the last 10 games
• +30.5 Betting Line on the Road: Have covered the spread in the last 10 games on the road

Point Spread

• -30.5 Betting Line: Have covered the spread in 2 of the last 10 games
• -30.5 Betting Line at Home: Have covered the spread in 2 of the last 10 home games

Total Points

• Game Totals: An average of 159.20 pts in the previous 10 games
• Game Totals on the Road: An average of 163.80 pts in the previous 10 games on the road
• Over 174.5: Covered in 2 of the previous 10 games
• Over 174.5 on the Road: Covered in 3 of the previous 10 games on the road
• Team Totals: Have scored an average of 77.90 pts and allowed 81.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 78.50 pts and allowed 85.30 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 152.10 pts in the previous 10 games
• Game Totals at Home: An average of 155.60 pts in the previous 10 home games
• Over 174.5: Covered in 2 of the previous 10 games
• Over 174.5 at Home: Covered in 2 of the previous 10 home games
• Team Totals: Have scored an average of 82.60 pts and allowed 69.50 pts in the last 10 games
• Team Totals at Home: Have scored an average of 85.30 pts and allowed 70.30 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	29-2	2571	1937	634	18-0	11-2	8W
Virginia	27-4	2507	2116	391	17-1	10-3	2W
Miami	24-7	2564	2192	372	15-4	9-3	1L
North Carolina	24-7	2474	2202	272	19-0	5-7	1L
Louisville	23-9	2724	2304	420	16-2	7-7	3W
Clemson	22-9	2309	2055	254	15-3	7-6	1W
California	21-11	2492	2344	148	17-4	4-7	2L
NC State	20-12	2688	2444	244	13-7	7-5	1W
Stanford	20-12	2431	2326	105	12-7	8-5	1L
SMU	20-13	2779	2561	218	17-3	3-10	1L
Virginia Tech	19-13	2521	2396	125	15-4	4-9	2L
Florida State	18-14	2573	2492	81	12-8	6-6	4W
Wake Forest	17-15	2540	2472	68	12-6	5-9	2W
Syracuse	15-17	2400	2376	24	12-6	3-11	6L
Notre Dame	13-18	2308	2335	-27	11-7	2-11	2L
Pittsburgh	13-20	2327	2370	-43	8-10	5-10	1L
Boston College	11-20	2090	2191	-101	10-10	1-10	1W
Georgia Tech	11-20	2287	2400	-113	10-10	1-10	12L

Mid-American	Overall	PF	PA	N. Pts	Home	Away	Strk
Miami (OH)	31-0	2818	2322	496	17-0	14-0	27W
Akron	26-5	2777	2285	492	16-2	10-3	7W
Kent State	22-8	2543	2410	133	15-3	7-5	2W
Bowling Green	18-13	2526	2213	313	12-7	6-6	2W
Toledo	17-14	2524	2381	143	11-4	6-10	1W
Buffalo	17-14	2427	2364	63	8-8	9-6	1L
UMass	16-15	2494	2402	92	11-6	5-9	1W
Ohio	15-16	2417	2429	-12	11-8	4-8	3L
Ball State	12-19	2093	2154	-61	8-7	4-12	4W
Central Michigan	10-21	2275	2384	-109	8-5	2-16	2L
Western Michigan	10-21	2318	2464	-146	7-8	3-13	3L
Eastern Michigan	9-21	2105	2231	-126	6-7	3-14	4L
Northern Illinois	9-21	2086	2334	-248	6-7	3-14	5L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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