Saint Louis vs Michigan Prediction, Picks & Odds | 21 Mar 2026
College Basketball Betting Preview: Saint Louis vs Michigan
No. 9 Saint Louis Billikens square off against No. 1 Michigan Wolverines in this NCAA Tournament Second Round matchup at KeyBank Center in Buffalo, with tip-off scheduled for 12:10 on Saturday, March 21.
We’re going for a modest total when Saint Louis and Michigan take to the court. Under 161.5 points could be on the money and our prediction is currently available at -110.
The Saint Louis Billikens (22-12, 5th in SoCon) secured a 102-77 win over the Georgia Bulldogs in the First Round.
The Michigan Wolverines (32-3, 1st in Big Ten) rolled to a 101-80 win over the Howard Bison in the First Round.
| NCAAB Regular Season | Overall | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|
Michigan
|
31-3 | 2952 | 2353 | 599 | 19-2 | 12-1 | 1L |
Saint Louis
|
28-5 | 2879 | 2294 | 585 | 21-2 | 7-3 | 1L |
Saint Louis vs Michigan Prediction & Picks
Head into Saint Louis vs Michigan with expert betting insights, including our main match prediction, expected scoreline, key player prop picks and a thoughtfully built bet builder.
Game Prediction
Let’s shoot for a total bet for this college matchup, with Under 161.5 points available at odds of -110. This betting pick looks to have plenty of juice in the price.
The college basketball handicappers at Sportsgambler.com stay on top of injuries and team form that could impact the outcome. We also leave no stone unturned when analyzing the latest stats to support every prediction.
Key Saint Louis vs Michigan stats:
Under 161.5 Probability
Looking at the latest betting odds, our pick has a 52.4% chance of winning. After careful examination, our analysts calculate this probability to be somewhere between 55-60%. It’s why we think it’s worth placing this college basketball bet.
There are different ways to maximise a potential profit on the Totals. Moving the line for your Under bet means the chance to secure bigger betting odds.
Give your bets a boost! Browse our comprehensive guide to find the latest betting offers and generous welcome bonuses.
Player Prop Picks
Elliot Cadeau (Michigan) is available at -108 to rack up Under 6.5 assists. There is a strong case for siding with him to fall short of the required total on the Player Assists line.
Latest Elliot Cadeau Player Prop Odds
Aday Mara (Michigan) can be wagered to register Under 14.5 points at -103. We’re expecting him to fall short when it comes to Player Points as the line looks high enough.
Latest Aday Mara Player Prop Odds
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Picks
Try out our same game parlay pick which starts with Under 161.5. We’ve also gone for Saint Louis +12.5 and Elliot Cadeau (Michigan) to get Under 6.5 assists.
There are many options when you place a same game parlay. You can go through the available basketball lines and identify your favorite picks before combining the odds on the bet slip. Personalised wagering doesn’t come any better.
Correct Score Prediction
73
-
81
Michigan
Should you wish to go for a speculative bet, try the Wolverines to win 81-73 on the correct score lines. This should be a fun wager which could potentially yield a huge return.
Saint Louis vs Michigan Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
The latest Moneyline betting odds give Michigan a 91% chance of winning this NCAA Tournament game which means they’re overwhelming -1000 favorites with the sportsbooks. For those wanting to oppose the market leader, you can get +640 about Saint Louis.
The spread is 12.5 and the total points line is currently 161.5. Basketball fans regularly enjoy the opportunity to bet on the Totals. If you’re going for Under 161.5, this outcome can be backed at -110.
If you’re wagering on college basketball, we recommend heading to the top betting apps and scanning through the many game lines and team props. There’s a chance to wager pre-game and in-game.
In terms of hitting the most buckets, favorite Yaxel Lendeborg is available at -122 to rack up Over 15.5 points. If you want to go Under, then -106 is available.
Latest regular season and playoff games stats.
Saint Louis Stats
Michigan Stats
- 6 wins and 4 defeats in the last 10 games
- 7 wins and 3 defeats in the last 10 games on the road
- +12.5 Betting Line: Have covered the spread in 8 of the last 10 games
- +12.5 Betting Line on the Road: Have covered the spread in 8 of the last 10 games on the road
- -12.5 Betting Line: Have covered the spread in 2 of the last 10 games
- -12.5 Betting Line at Home: Have covered the spread in 3 of the last 10 home games
- Game Totals: An average of 154.50 pts in the previous 10 games
- Game Totals on the Road: An average of 154.20 pts in the previous 10 games on the road
- Over 161.5: Covered in 4 of the previous 10 games
- Over 161.5 on the Road: Covered in 2 of the previous 10 games on the road
- Team Totals: Have scored an average of 79.80 pts and allowed 74.70 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 80.70 pts and allowed 73.50 pts in the last 10 games on the road
- Game Totals: An average of 151.30 pts in the previous 10 games
- Game Totals at Home: An average of 152.20 pts in the previous 10 home games
- Over 161.5: Covered in 3 of the previous 10 games
- Over 161.5 at Home: Covered in 3 of the previous 10 home games
- Team Totals: Have scored an average of 78.80 pts and allowed 72.50 pts in the last 10 games
- Team Totals at Home: Have scored an average of 82.40 pts and allowed 69.80 pts in the last 10 home games
NCAAB Regular Season Table Select Season
| Big Ten | Overall | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|
|
Michigan
|
31-3 | 2952 | 2353 | 599 | 19-2 | 12-1 | 1L |
Nebraska
|
26-6 | 2473 | 2119 | 354 | 19-3 | 7-3 | 1L |
Michigan State
|
25-7 | 2526 | 2189 | 337 | 17-3 | 8-4 | 2L |
Purdue
|
27-8 | 2858 | 2455 | 403 | 16-5 | 11-3 | 4W |
Illinois
|
24-8 | 2700 | 2234 | 466 | 15-6 | 9-2 | 1L |
Wisconsin
|
24-10 | 2822 | 2581 | 241 | 16-2 | 8-8 | 1L |
UCLA
|
23-11 | 2643 | 2414 | 229 | 18-3 | 5-8 | 1L |
Ohio State
|
21-12 | 2633 | 2402 | 231 | 15-5 | 6-7 | 1L |
Iowa
|
21-12 | 2482 | 2177 | 305 | 17-3 | 4-9 | 1L |
Indiana
|
18-14 | 2501 | 2309 | 192 | 15-6 | 3-8 | 2L |
USC
|
18-14 | 2515 | 2494 | 21 | 11-7 | 7-7 | 8L |
Washington
|
16-17 | 2545 | 2430 | 115 | 11-6 | 5-11 | 1L |
Minnesota
|
15-17 | 2241 | 2193 | 48 | 13-8 | 2-9 | 1L |
Northwestern
|
15-19 | 2487 | 2447 | 40 | 11-9 | 4-10 | 1L |
Rutgers
|
14-19 | 2329 | 2479 | -150 | 11-7 | 3-12 | 1L |
Oregon
|
12-20 | 2267 | 2366 | -99 | 10-10 | 2-10 | 1L |
Penn State
|
12-20 | 2358 | 2539 | -181 | 10-10 | 2-10 | 3L |
Maryland
|
12-21 | 2300 | 2527 | -227 | 9-8 | 3-13 | 1L |
| Atlantic 10 | Overall | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|
|
Saint Louis
|
28-5 | 2879 | 2294 | 585 | 21-2 | 7-3 | 1L |
VCU
|
27-7 | 2773 | 2430 | 343 | 19-3 | 8-4 | 6W |
George Mason
|
23-9 | 2347 | 2160 | 187 | 17-3 | 6-6 | 1L |
Dayton
|
23-11 | 2528 | 2376 | 152 | 16-4 | 7-7 | 1L |
Saint Joseph's
|
22-11 | 2419 | 2306 | 113 | 16-3 | 6-8 | 1L |
Davidson
|
20-13 | 2367 | 2225 | 142 | 12-8 | 8-5 | 1L |
Duquesne
|
18-15 | 2584 | 2481 | 103 | 13-7 | 5-8 | 1L |
George Washington
|
18-15 | 2708 | 2433 | 275 | 13-5 | 5-10 | 1L |
Fordham
|
17-15 | 2235 | 2095 | 140 | 12-8 | 5-7 | 1L |
Rhode Island
|
16-16 | 2236 | 2182 | 54 | 10-7 | 6-9 | 2L |
St. Bonaventure
|
17-17 | 2596 | 2532 | 64 | 10-7 | 7-10 | 1L |
Richmond
|
15-17 | 2455 | 2366 | 89 | 11-8 | 4-9 | 4L |
La Salle
|
9-23 | 2148 | 2370 | -222 | 7-9 | 2-14 | 2L |
Loyola Chicago
|
9-24 | 2204 | 2500 | -296 | 6-12 | 3-12 | 1L |
- Overall = Overall Wins-Losses
- PF = Total Points For
- PA = Total Points Against
- N. Pts = Point Differential
- Home = Home Record
- Away = Away Record
- Strk = Current Streak
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