Saint Louis vs Michigan Prediction, Picks & Odds | 21 Mar 2026

College Basketball Betting Preview: Saint Louis vs Michigan

No. 9 Saint Louis Billikens square off against No. 1 Michigan Wolverines in this NCAA Tournament Second Round matchup at KeyBank Center in Buffalo, with tip-off scheduled for 11:10 on Saturday, March 21.

We’re going for a modest total when Saint Louis and Michigan take to the court. Under 161.5 points could be on the money and our prediction is currently available at -110.

The Saint Louis Billikens (22-12, 5th in SoCon) secured a 102-77 win over the Georgia Bulldogs in the First Round.

The Michigan Wolverines (32-3, 1st in Big Ten) rolled to a 101-80 win over the Howard Bison in the First Round.

NCAAB Regular Season	Overall	PF	PA	N. Pts	Home	Away	Strk
Michigan	0-0	0	0	0	0-0	0-0	-
Saint Louis	0-0	0	0	0	0-0	0-0	-

View Full Standings

Saint Louis vs Michigan Prediction & Picks

Head into Saint Louis vs Michigan with expert betting insights, including our main match prediction, expected scoreline, key player prop picks and a thoughtfully built bet builder.

Game Prediction

Let’s shoot for a total bet for this college matchup, with Under 161.5 points available at odds of -110. This betting pick looks to have plenty of juice in the price.

The college basketball handicappers at Sportsgambler.com stay on top of injuries and team form that could impact the outcome. We also leave no stone unturned when analyzing the latest stats to support every prediction.

Key Saint Louis vs Michigan stats:

• The 161.5 line hasn’t been covered in 16 of the last 19 SLU games on the road.
• The 161.5 line hasn’t been covered in 8 of the last 10 SLU games on the road.
• The 161.5 line hasn’t been covered in 15 of the last 20 Michigan games.
• The 161.5 line hasn’t been covered in 7 of the last 10 Michigan games.

Under 161.5 Probability

Looking at the latest betting odds, our pick has a 52.4% chance of winning. After careful examination, our analysts calculate this probability to be somewhere between 55-60%. It’s why we think it’s worth placing this college basketball bet.

There are different ways to maximise a potential profit on the Totals. Moving the line for your Under bet means the chance to secure bigger betting odds.

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Our Game Prediction

Under 161.5 Points @ -110 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Mar 20, 16:02). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Elliot Cadeau Under 6.5 Assists -108

Elliot Cadeau (Michigan) is available at -108 to rack up Under 6.5 assists. There is a strong case for siding with him to fall short of the required total on the Player Assists line.

Latest Elliot Cadeau Player Prop Odds

Points

Over 11.5

-119

Under 11.5

-109

Assists

Over 7.5

+115

Under 7.5

-149

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Aday Mara Under 14.5 Points -103

Aday Mara (Michigan) can be wagered to register Under 14.5 points at -103. We’re expecting him to fall short when it comes to Player Points as the line looks high enough.

Latest Aday Mara Player Prop Odds

Points

Over 13.5

-125

Under 13.5

-103

Rebounds

Over 7.5

+117

Under 7.5

-152

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Saint Louis 73 - 81 Michigan

Should you wish to go for a speculative bet, try the Wolverines to win 81-73 on the correct score lines. This should be a fun wager which could potentially yield a huge return.

T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Saint Louis vs Michigan Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The latest Moneyline betting odds give Michigan a 92% chance of winning this NCAA Tournament game which means they’re overwhelming -1111 favorites with the sportsbooks. For those wanting to oppose the market leader, you can get +680 about Saint Louis.

The spread is 12.5 and the total points line is currently 161.5. Basketball fans regularly enjoy the opportunity to bet on the Totals. If you’re going for Under 161.5, this outcome can be backed at -105.

If you’re wagering on college basketball, we recommend heading to the top betting apps and scanning through the many game lines and team props. There’s a chance to wager pre-game and in-game.

Moneyline

SLU

+680

Michigan

-1111

Point Spread

SLU +12.5

-105

Michigan -12.5

-115

Total Points

Under 161.5

-105

Over 161.5

-115

In terms of hitting the most buckets, favorite Yaxel Lendeborg is available at -108 to rack up Over 15.5 points. If you want to go Under, then -120 is available.

Yaxel Lendeborg (Michigan)

Over 15.5

-108

Under 15.5

-120

Morez Johnson Jr. (Michigan)

Over 14.5

-120

Under 14.5

-108

Aday Mara (Michigan)

Over 13.5

-125

Under 13.5

-103

Robbie Avila (SLU)

Over 13.5

-110

Under 13.5

-118

Elliot Cadeau (Michigan)

Over 11.5

-119

Under 11.5

-109

Nimari Burnett (Michigan)

Over 11.5

+107

Under 11.5

-139

Amari McCottry (SLU)

Over 10.5

-109

Under 10.5

-119

Dion Brown (SLU)

Over 10.5

-103

Under 10.5

-125

Trey McKenney (Michigan)

Over 10.5

-100

Under 10.5

-130

Trey Green (SLU)

Over 9.5

-112

Under 9.5

-115

Elliot Cadeau (Michigan)

Over 7.5

+115

Under 7.5

-149

Morez Johnson Jr. (Michigan)

Over 7.5

-125

Under 7.5

-103

Aday Mara (Michigan)

Over 7.5

+117

Under 7.5

-152

Yaxel Lendeborg (Michigan)

Over 6.5

-133

Under 6.5

+103

Robbie Avila (SLU)

Over 5.5

+117

Under 5.5

-152

Amari McCottry (SLU)

Over 5.5

-115

Under 5.5

-112

Nimari Burnett (Michigan)

Over 3.5

+110

Under 3.5

-143

An increasing number of bettors are now enjoying micro betting on college basketball and it’s something which is available on an in-game basis. Wait for the action to start and then wager on something specific to happen.

Latest regular season and playoff games stats.

Saint Louis Stats

Michigan Stats

Moneyline

• 6 wins and 4 defeats in the last 10 games

Moneyline

• 8 wins and 2 defeats in the last 10 games

Point Spread

• +12.5 Betting Line: Have covered the spread in 8 of the last 10 games

Point Spread

• -12.5 Betting Line: Have covered the spread in 2 of the last 10 games

Total Points

• Game Totals: An average of 154.50 pts in the previous 10 games
• Over 161.5: Covered in 4 of the previous 10 games
• Team Totals: Have scored an average of 79.80 pts and allowed 74.70 pts in the last 10 games

Total Points

• Game Totals: An average of 151.30 pts in the previous 10 games
• Over 161.5: Covered in 3 of the previous 10 games
• Team Totals: Have scored an average of 78.80 pts and allowed 72.50 pts in the last 10 games

NCAAB Regular Season Table Select Season 2026/20272025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big Ten	Overall	PF	PA	N. Pts	Home	Away	Strk
Illinois	0-0	0	0	0	0-0	0-0	-
Oregon	0-0	0	0	0	0-0	0-0	-
Washington	0-0	0	0	0	0-0	0-0	-
UCLA	0-0	0	0	0	0-0	0-0	-
USC	0-0	0	0	0	0-0	0-0	-
Rutgers	0-0	0	0	0	0-0	0-0	-
Purdue	0-0	0	0	0	0-0	0-0	-
Penn State	0-0	0	0	0	0-0	0-0	-
Ohio State	0-0	0	0	0	0-0	0-0	-
Indiana	0-0	0	0	0	0-0	0-0	-
Northwestern	0-0	0	0	0	0-0	0-0	-
Nebraska	0-0	0	0	0	0-0	0-0	-
Minnesota	0-0	0	0	0	0-0	0-0	-
Michigan	0-0	0	0	0	0-0	0-0	-
Michigan State	0-0	0	0	0	0-0	0-0	-
Maryland	0-0	0	0	0	0-0	0-0	-
Iowa	0-0	0	0	0	0-0	0-0	-
Wisconsin	0-0	0	0	0	0-0	0-0	-

Atlantic 10	Overall	PF	PA	N. Pts	Home	Away	Strk
Davidson	0-0	0	0	0	0-0	0-0	-
Dayton	0-0	0	0	0	0-0	0-0	-
Duquesne	0-0	0	0	0	0-0	0-0	-
Fordham	0-0	0	0	0	0-0	0-0	-
George Mason	0-0	0	0	0	0-0	0-0	-
George Washington	0-0	0	0	0	0-0	0-0	-
La Salle	0-0	0	0	0	0-0	0-0	-
Loyola Chicago	0-0	0	0	0	0-0	0-0	-
Rhode Island	0-0	0	0	0	0-0	0-0	-
Richmond	0-0	0	0	0	0-0	0-0	-
St. Bonaventure	0-0	0	0	0	0-0	0-0	-
Saint Joseph's	0-0	0	0	0	0-0	0-0	-
Saint Louis	0-0	0	0	0	0-0	0-0	-
VCU	0-0	0	0	0	0-0	0-0	-

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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