Santa Clara vs Saint Louis Prediction, Picks & Odds | 27 Nov 2025

College Basketball Betting Preview: Santa Clara vs Saint Louis

The Santa Clara Broncos go up against the Saint Louis Billikens, with tip-off scheduled for 19:00 on Thursday, November 27.

There’s merit in backing Santa Clara on the Moneyline considering our prediction is that the road team will have the edge over Saint Louis. Especially as +105 is on offer about this happening.

Saint Louis Billikens won their previous game which was at home. It was a 91-60 triumph against Purdue Fort Wayne Mastodons.

Santa Clara Broncos won their last game, beating Louisiana Ragin' Cajuns at home. It was a 80-43 win.

Head-to-Head Statistics

The last head-to-head saw Santa Clara claim a 85-78 win over Saint Louis.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Saint Louis	28-5	2879	2294	585	21-2	7-3	1L
Santa Clara	26-8	2817	2463	354	16-3	10-5	1L

View Full Standings

Santa Clara vs Saint Louis Prediction & Picks

We dive into the top Santa Clara vs Saint Louis betting angles, including our main match prediction, best correct score play and a bet builder tailored for value.

Game Prediction

There’s a juicy +105 that Santa Clara are able to get the better of their opponents. This value pick can be wagered on the Moneyline for this college showdown.

Tracking injury updates is a big part of our college hoops analysis and team news plays a major role in shaping our basketball picks. We combine this with recent form and the most important stats to get a complete picture.

Key Santa Clara vs Saint Louis stats:

• Santa Clara have won 6 consecutive games.
• Santa Clara have won 8 of their last 10 games.
• Santa Clara have won 14 of their last 20 games.

Santa Clara Moneyline Probability

When you look at the latest odds, our pick has a 48.8% chance of landing a return. However, we have this number between 55-60% based on our in-depth research. It’s the reason why we are recommending this college basketball bet.

If you can correctly predict that Santa Clara will win along with the number of points, then you are able to combine the two options and getting larger odds on the Match Result & Total market.

Don’t place a bet without checking our guide full of top-tier betting offers, from free bets to welcome bonus incentives.

Our Game Prediction

Santa Clara Moneyline @ +105 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Nov 26, 23:55). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Santa Clara 79 - 76 Saint Louis

We’ll roll the dice and go for Santa Clara to register a 79-76 victory. We don’t think that there will be too much between the teams and we’re happy to take the massive odds.

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Santa Clara vs Saint Louis Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

You can choose Saint Louis at -122 or alternatively Santa Clara who have betting odds of +102. This means the leading sportsbooks give the visiting team a 50% chance of success.

There is a spread of 1.5 and total points has a line of 158.5. There is no denying the popularity of betting on the Totals. If you fancy Under 158.5, then the odds are -110.

Consider every angle when placing your college hoops bets. The top basketball betting sites offer a huge selection of game lines and team props, and it’s all about finding a wager that fits your prediction of the game.

Moneyline

Santa Clara

+102

SLU

-122

Point Spread

Santa Clara +1.5

-114

SLU -1.5

-106

Total Points

Under 158.5

-110

Over 158.5

-110

The gambling sites will have player props available for each game. Check out the various betting odds and take a view on whether a player’s Total Points, Three-Pointers, Blocks or Steals will hit over or under a certain line.

There are some exciting college basketball micro betting lines that are created and they are available in-game. Among them are Next Field Goal, where you select if the shot will be a two or three-pointer. The long-ball option pays better, and in today’s game, you can never discount the three-pointer.

Latest regular season and playoff games stats.

Santa Clara Stats

Saint Louis Stats

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 9 wins and 1 defeat in the last 10 home games

Point Spread

• +1.5 Betting Line: Have covered the spread in 8 of the last 10 games
• +1.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road

Point Spread

• -1.5 Betting Line: Have covered the spread in 7 of the last 10 games
• -1.5 Betting Line at Home: Have covered the spread in 9 of the last 10 home games

Total Points

• Game Totals: An average of 151.20 pts in the previous 10 games
• Game Totals on the Road: An average of 160.70 pts in the previous 10 games on the road
• Over 159.5: Covered in 4 of the previous 10 games
• Over 159.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 84.90 pts and allowed 66.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 85.50 pts and allowed 75.20 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 161.60 pts in the previous 10 games
• Game Totals at Home: An average of 161.90 pts in the previous 10 home games
• Over 159.5: Covered in 4 of the previous 10 games
• Over 159.5 at Home: Covered in 4 of the previous 10 home games
• Team Totals: Have scored an average of 86.00 pts and allowed 75.60 pts in the last 10 games
• Team Totals at Home: Have scored an average of 90.40 pts and allowed 71.50 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic 10	Overall	PF	PA	N. Pts	Home	Away	Strk
Saint Louis	28-5	2879	2294	585	21-2	7-3	1L
VCU	27-7	2773	2430	343	19-3	8-4	6W
George Mason	23-9	2347	2160	187	17-3	6-6	1L
Dayton	23-11	2528	2376	152	16-4	7-7	1L
Saint Joseph's	22-11	2419	2306	113	16-3	6-8	1L
Davidson	20-13	2367	2225	142	12-8	8-5	1L
Duquesne	18-15	2584	2481	103	13-7	5-8	1L
George Washington	18-15	2708	2433	275	13-5	5-10	1L
Fordham	17-15	2235	2095	140	12-8	5-7	1L
Rhode Island	16-16	2236	2182	54	10-7	6-9	2L
St. Bonaventure	17-17	2596	2532	64	10-7	7-10	1L
Richmond	15-17	2455	2366	89	11-8	4-9	4L
La Salle	9-23	2148	2370	-222	7-9	2-14	2L
Loyola Chicago	9-24	2204	2500	-296	6-12	3-12	1L

West Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Gonzaga	30-3	2809	2178	631	20-0	10-3	2W
Saint Mary's	27-5	2502	2066	436	18-1	9-4	1L
Santa Clara	26-8	2817	2463	354	16-3	10-5	1L
Seattle	20-13	2373	2211	162	15-5	5-8	1L
Pacific	18-15	2399	2271	128	13-3	5-12	1L
Oregon State	17-16	2347	2447	-100	13-8	4-8	1L
San Francisco	17-16	2464	2414	50	11-6	6-10	1L
Loyola Marymount	15-17	2376	2306	70	10-10	5-7	2L
Portland	14-19	2426	2582	-156	12-6	2-13	1L
San Diego	12-21	2458	2570	-112	9-8	3-13	1L
Washington State	11-20	2435	2495	-60	9-8	2-12	4L
Pepperdine	9-23	2312	2546	-234	7-10	2-13	1L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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