Southern Illinois vs Bradley Prediction, Picks & Odds | 21 Dec 2025

College Basketball Betting Preview: Southern Illinois vs Bradley

The Southern Illinois Salukis face the Bradley Braves, with tip-off scheduled for 14:00 on Sunday, December 21.

Bradley are capable of covering the -5.5 line when they go up against Southern Illinois. We’re confident of a strong showing and a bet against the spread could be the best play at -120.

Southern Illinois Salukis lost when they last took to the court. They were turned over 75-68 at home to Illinois State Redbirds.

Bradley Braves won last time out by a 108-99 (OT) scoreline. It was on the road against Indiana State Sycamores.

Head-to-Head Statistics

Bradley won the most recent matchup between these teams. A 78-64 victory was registered against Southern Illinois. Bradley have six straight victories against Southern Illinois. They’ve also claimed 7 wins in the past 10 head-to-head meetings.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Bradley	21-12	2560	2422	138	17-4	4-8	1L
Southern Illinois	16-16	2336	2226	110	8-8	8-8	1L

View Full Standings

Southern Illinois vs Bradley Prediction & Picks

Get fully prepped for Southern Illinois vs Bradley with our betting guide, featuring our expert match pick, predicted scoreline and a value-focused bet builder. Read on for the full breakdown.

Game Prediction

We’re confident of backing Bradley to cover the -5.5 spread in this college game. This is a more than generous line and the favorites look a value bet at odds of -120.

The handicappers at Sportsgambler.com stay on top of the latest injuries, while recent form also shapes our basketball predictions. We combine this insight with up-to-date college hoops stats for sharper picks.

Key Southern Illinois vs Bradley stats:

• The -5.5 line has been covered by Bradley in 4 of their last 5 games.
• The -5.5 line has been covered by Bradley in 6 of their last 10 games.
• The -5.5 line has been covered by Bradley in 3 consecutive games.
• The +5.5 line hasn’t been covered by Southern Illinois in 3 of their last 5 games on the road.
• The +5.5 line hasn’t been covered by Southern Illinois in 6 of their last 10 games on the road.
• The +5.5 line hasn’t been covered by Southern Illinois in 2 consecutive games.
• The -5.5 line has been covered by Bradley in 3 consecutive games against Southern Illinois.

Bradley -5.5 Probability

According to the best betting apps, our pick has a 54.6% chance of delivering a return. In our opinion, there’s actually a probability of success closer to 60%. It is the reason why we are recommending this college basketball wager.

It’s possible to move the line for your selection and this allows bettors to get increasingly bigger odds. If you’re looking for more juice, then this option could tick the boxes.

Searching for betting perks? Explore our bonus guide for the freshest sportsbook promo codes, free bets, and offers today.

Our Game Prediction

Bradley -5.5 @ -120 Bet Now

BetMGM Promo Up To $1500 in Bonus Bets Get Bonus T&C apply. Gamble responsibly 18+

Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Dec 20, 20:57). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Southern Illinois 72 - 82 Bradley

We’re going for Bradley to win by a 82-72 scoreline, something which is available at huge odds. This speculative wager can provide a big return for a small stake.

T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Southern Illinois vs Bradley Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The sportsbooks’ betting odds have Bradley as -278 favorites for this college game, implying that they are 74% likely to win. For those wanting to oppose the market leader, you can get +225 about Southern Illinois.

The spread is calculated to be 5.5, while total points comes in at 149.5. There are many ways to bet on basketball including the Totals. If you’re wanting to back Over 149.5, the odds are -110.

The best betting sites offer stacks of team props and game lines when it comes to most college basketball contests. Make sure you look through all the available options before deciding which bet to place.

Moneyline

Southern Illinois

+225

Bradley

-278

Point Spread

Southern Illinois +5.5

-102

Bradley -5.5

-120

Total Points

Under 149.5

-110

Over 149.5

-110

Should you be more interested in a specific individual who is competing, check out the gambling sites’ prop bets where you can pick out player lines that focus on performance rather than the game result.

It’s good to consider all wagering options when it comes to college basketball and micro betting can be an exciting way to get involved in the action. When everything goes in-game, consider whether the next shot will be a Two or a Three-pointer.

Latest regular season and playoff games stats.

Southern Illinois Stats

Bradley Stats

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +5.5 Betting Line: Have covered the spread in 5 of the last 10 games
• +5.5 Betting Line on the Road: Have covered the spread in 4 of the last 10 games on the road

Point Spread

• -5.5 Betting Line: Have covered the spread in 6 of the last 10 games
• -5.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games

Total Points

• Game Totals: An average of 153.40 pts in the previous 10 games
• Game Totals on the Road: An average of 152.00 pts in the previous 10 games on the road
• Over 149.5: Covered in 5 of the previous 10 games
• Over 149.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 77.10 pts and allowed 76.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 72.70 pts and allowed 79.30 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 151.10 pts in the previous 10 games
• Game Totals at Home: An average of 143.60 pts in the previous 10 home games
• Over 149.5: Covered in 4 of the previous 10 games
• Over 149.5 at Home: Covered in 3 of the previous 10 home games
• Team Totals: Have scored an average of 79.90 pts and allowed 71.20 pts in the last 10 games
• Team Totals at Home: Have scored an average of 77.70 pts and allowed 65.90 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Missouri Valley	Overall	PF	PA	N. Pts	Home	Away	Strk
Belmont	26-6	2684	2347	337	15-3	11-3	2L
Northern Iowa	23-12	2447	2144	303	13-5	10-7	5W
Bradley	21-12	2560	2422	138	17-4	4-8	1L
Illinois State	20-12	2404	2190	214	15-4	5-8	1L
Murray State	20-12	2667	2558	109	14-4	6-8	2L
UIC	19-15	2567	2379	188	11-7	8-8	1L
Valparaiso	17-15	2278	2300	-22	13-4	4-11	1L
Southern Illinois	16-16	2336	2226	110	8-8	8-8	1L
Drake	14-20	2552	2544	8	7-12	7-8	1L
Indiana State	11-21	2354	2383	-29	8-7	3-14	1L
Evansville	7-25	2143	2447	-304	5-12	2-13	2L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

Top Basketball Pages