Syracuse vs SMU Prediction, Picks & Odds | 10 Mar 2026

College Basketball Betting Preview: Syracuse vs SMU

The Syracuse Orange battle the SMU Mustangs, with tip-off scheduled for 16:30 on Tuesday, March 10.

There’s a strong case for backing SMU on the spread when they face Syracuse. The line looks really appealing considering you can get -120 when it comes to the favorites at -4.5.

Syracuse Orange were beaten 71-69 (OT) in their previous game, being turned over at home to Pittsburgh Panthers.

SMU Mustangs were defeated in their last game. On the road, they suffered a 91-78 reverse against Florida State Seminoles.

Head-to-Head Statistics

It was a 79-78 win for Syracuse when they last played SMU. SMU have won two of the past 3 games that these teams have played.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
SMU	19-12	2635	2430	205	16-3	3-9	4L
Syracuse	15-16	2331	2290	41	12-6	3-10	5L

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Syracuse vs SMU Prediction & Picks

Explore our best Syracuse vs SMU picks, including a main match prediction, correct score forecast and a bet builder ready to use. Scroll down for full analysis.

Game Prediction

SMU should be able to cover the -4.5 betting line in this college matchup. We’re confident of a strong showing and a bet against the spread could be the best play at -120.

The college basketball handicappers at Sportsgambler.com stay on top of injuries and team form that could impact the outcome. We also leave no stone unturned when analyzing the latest stats to support every prediction.

Key Syracuse vs SMU stats:

• The -4.5 line has been covered by SMU in 13 of their last 20 games at home.
• The -4.5 line has been covered by SMU in 3 of their last 5 games at home.
• The +4.5 line hasn’t been covered by Syracuse in 7 consecutive games on the road.
• The +4.5 line hasn’t been covered by Syracuse in 8 of their last 10 games on the road.
• The +4.5 line hasn’t been covered by Syracuse in 13 of their last 20 games on the road.

SMU -4.5 Probability

The top betting apps imply that our pick has a 54.6% prospect of delivering a return. After careful examination, our experts have this probability close to 60%. This is why we can recommend this college basketball wager.

Buying and selling points with a sportsbook gives you the chance to choose different lines. The former will mean shorter odds, while a sell leads to a bigger potential return.

Discover valuable betting promo codes, welcome offers, and free bets in our updated bonus guide before you play.

Our Game Prediction

SMU -4.5 @ -120 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Mar 9, 21:02). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Syracuse 79 - 86 SMU

Should you wish to go for a speculative bet, try the Mustangs to win 86-79 on the correct score lines. This should be a fun wager which could potentially yield a huge return.

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Syracuse vs SMU Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

With the sportsbooks giving them a 67% probability of winning this college game, SMU might be a popular parlay pick. That is reflected in their -200 Moneyline betting odds. If you’re looking for an alternative angle, Syracuse are trading at +164.

There is a spread of 4.5 and total points has a line of 156.5. There are many ways to bet on basketball including the Totals. The Over 156.5 selection is available to back at -110.

If you’re planning to place a bet on a college basketball contest, visit the best sportsbooks and check out the wide range of team props and game lines. Find the lines which are the most attractive.

Moneyline

Syracuse

+164

SMU

-200

Point Spread

Syracuse +4.5

-102

SMU -4.5

-120

Total Points

Under 156.5

-110

Over 156.5

-110

The gambling sites will have player props available for each game. Check out the various betting odds and take a view on whether a player’s Total Points, Three-Pointers, Blocks or Steals will hit over or under a certain line.

Micro betting is an exciting way to wager on college basketball. There are many live lines and it’s a simple case of predicting what is going to happen. Next Field Goal, where you select if the shot will be a two or three-pointer are among the options.

Latest regular season and playoff games stats.

Syracuse Stats

SMU Stats

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +4.5 Betting Line: Have covered the spread in 4 of the last 10 games
• +4.5 Betting Line on the Road: Have covered the spread in 2 of the last 10 games on the road

Point Spread

• -4.5 Betting Line: Have covered the spread in 4 of the last 10 games
• -4.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games

Total Points

• Game Totals: An average of 157.30 pts in the previous 10 games
• Game Totals on the Road: An average of 154.80 pts in the previous 10 games on the road
• Over 157.5: Covered in 5 of the previous 10 games
• Over 157.5 on the Road: Covered in 4 of the previous 10 games on the road
• Team Totals: Have scored an average of 75.00 pts and allowed 82.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 71.50 pts and allowed 83.30 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 161.80 pts in the previous 10 games
• Game Totals at Home: An average of 163.60 pts in the previous 10 home games
• Over 157.5: Covered in 6 of the previous 10 games
• Over 157.5 at Home: Covered in 7 of the previous 10 home games
• Team Totals: Have scored an average of 81.60 pts and allowed 80.20 pts in the last 10 games
• Team Totals at Home: Have scored an average of 86.50 pts and allowed 77.10 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	29-2	2571	1937	634	18-0	11-2	8W
Virginia	27-4	2507	2116	391	17-1	10-3	2W
Miami	24-7	2564	2192	372	15-4	9-3	1L
North Carolina	24-7	2474	2202	272	19-0	5-7	1L
Clemson	22-9	2309	2055	254	15-3	7-6	1W
Louisville	22-9	2662	2246	416	15-2	7-7	2W
California	21-10	2403	2249	154	17-4	4-6	1L
Stanford	20-11	2368	2262	106	12-6	8-5	4W
NC State	19-12	2590	2356	234	12-7	7-5	4L
SMU	19-12	2635	2430	205	16-3	3-9	4L
Virginia Tech	19-12	2432	2301	131	15-3	4-9	1L
Florida State	17-14	2478	2403	75	11-8	6-6	3W
Wake Forest	16-15	2445	2383	62	12-6	4-9	1W
Syracuse	15-16	2331	2290	41	12-6	3-10	5L
Notre Dame	13-18	2308	2335	-27	11-7	2-11	2L
Pittsburgh	12-19	2175	2209	-34	8-10	4-9	1W
Boston College	11-20	2090	2191	-101	10-10	1-10	1W
Georgia Tech	11-20	2287	2400	-113	10-10	1-10	12L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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