Virginia vs Louisville Prediction, Picks & Odds | 13 Jan 2026

College Basketball Betting Preview: Virginia vs Louisville

The Virginia Cavaliers go up against the Louisville Cardinals, with tip-off scheduled for 19:00 on Tuesday, January 13.

There’s a strong case for backing Louisville on the spread when they face Virginia. The line looks really appealing considering you can get -110 when it comes to the favorites at -3.5.

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Virginia Cavaliers won their previous game, beating Stanford Cardinal at home. It was a 70-55 win.

Louisville Cardinals were winners last time out. It was a 75-62 home victory against Boston College Eagles.

Head-to-Head Statistics

Louisville have beaten Virginia in their most recent meetings. On the road, a 70-50 scoreline was enjoyed before a home win by 81-67. The previous 10 games featuring these teams have resulted in eight Virginia victories.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Virginia	14-2	1361	1069	292	11-0	3-2	3W
Louisville	12-4	1413	1114	299	9-1	3-3	1W

View Full Standings

Virginia vs Louisville Prediction & Picks

Step into Virginia vs Louisville with confidence, armed with our expert match prediction, likely scoreline and a custom-built bet builder for maximum value.

Game Prediction

We are predicting that Louisville will cover the spread in this college contest. -3.5 seems a more than generous line and you can get -110 that the favorites will win by a bigger margin.

The college hoops handicappers at Sportsgambler.com start by analyzing recent form and staying on top of injury news before making any basketball picks. From there, we interpret the story the stats are telling to help shape our predictions.

Key Virginia vs Louisville stats:

• The -3.5 line has been covered by Louisville in 9 of their last 10 games at home.
• The -3.5 line has been covered by Louisville in 16 of their last 20 games at home.
• The +3.5 line hasn’t been covered by Virginia in 11 of their last 19 games on the road.
• The -3.5 line has been covered by Louisville in 2 consecutive games against Virginia.

Louisville -3.5 Probability

The top betting sites are estimating that there is a 52.4% likelihood of this pick winning. After careful examination, our analysts calculate this probability to be closer to 60%. This is why we regard this as a value bet.

If you’re hunting for bigger odds and feel confident your selection is going to perform well, then consider moving the line and land a bigger potential return.

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Our Game Prediction

Louisville -3.5 @ -110 Bet Now

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Correct Score Prediction

Virginia 75 - 82 Louisville

There are lots of different betting angles including the chance to back Louisville on the correct score lines. For example, a 82-75 victory in their favor is available at massive odds.

Virginia vs Louisville Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

The sportsbooks have Louisville at -192 when it comes to the Moneyline betting, implying the favorites are 66% likely to win this game according to the latest odds. For those wanting to back Virginia, you will find +158 about the underdogs.

The current spread is 3.5 and the total points line is 153.5. A Total bet is always available and can often provide value selections. If you want to back Over 153.5, it’s -110.

College basketball bettors are spoilt for choice thanks to the huge selection of game lines and team props which are available for most matchups on the coupon. Head to the top betting apps and find the best value picks.

Moneyline

Virginia

+158

Louisville

-192

Point Spread

Virginia +3.5

-110

Louisville -3.5

-110

Total Points

Under 153.5

-110

Over 153.5

-110

If you’re looking for an alternative to the main game lines, check out the player props instead. It’s great to wager on Total Points, Three-Pointers, Assists, Steals, Blocks and Rebounds as potential options.

You don’t have to wait for the final outcome when it comes to college basketball micro betting. Instead, there’s the opportunity to wager on live lines which tend to be settled in a shorter space of time and the in-game odds are always changing.

Latest regular season and playoff games stats.

Virginia Stats

Louisville Stats

Moneyline

• 9 wins and 1 defeat in the last 10 games
• 5 wins and 5 defeats in the last 10 games on the road

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 9 wins and 1 defeat in the last 10 home games

Point Spread

• +3.5 Betting Line: Have covered the spread in 9 of the last 10 games
• +3.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• -3.5 Betting Line: Have covered the spread in 6 of the last 10 games
• -3.5 Betting Line at Home: Have covered the spread in 9 of the last 10 home games

Total Points

• Game Totals: An average of 150.70 pts in the previous 10 games
• Game Totals on the Road: An average of 151.60 pts in the previous 10 games on the road
• Over 153.5: Covered in 4 of the previous 10 games
• Over 153.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 84.20 pts and allowed 66.50 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 75.70 pts and allowed 75.90 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 156.00 pts in the previous 10 games
• Game Totals at Home: An average of 159.40 pts in the previous 10 home games
• Over 153.5: Covered in 6 of the previous 10 games
• Over 153.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 84.00 pts and allowed 72.00 pts in the last 10 games
• Team Totals at Home: Have scored an average of 94.40 pts and allowed 65.00 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	15-1	1388	1065	323	10-0	5-1	4W
Miami	14-2	1411	1107	304	11-1	3-1	9W
Virginia	14-2	1361	1069	292	11-0	3-2	3W
North Carolina	14-2	1307	1073	234	12-0	2-2	1W
Clemson	14-3	1323	1116	207	10-0	4-3	7W
Virginia Tech	13-4	1399	1254	145	11-1	2-3	1W
Stanford	13-4	1308	1201	107	8-3	5-1	1L
California	13-4	1357	1190	167	13-1	0-3	2L
Louisville	12-4	1413	1114	299	9-1	3-3	1W
SMU	12-4	1426	1233	193	11-0	1-4	2L
NC State	12-5	1471	1211	260	9-3	3-2	2W
Syracuse	11-5	1196	1051	145	8-2	3-3	2W
Notre Dame	10-6	1176	1077	99	8-2	2-4	2L
Wake Forest	10-7	1390	1282	108	8-3	2-4	2L
Georgia Tech	10-7	1292	1225	67	10-3	0-4	2L
Pittsburgh	7-9	1171	1113	58	6-5	1-4	3L
Florida State	7-9	1327	1301	26	7-5	0-4	3L
Boston College	7-9	1104	1086	18	6-6	1-3	3L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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