Clemson vs West Virginia Prediction, Picks & Odds | 21 Nov 2025

College Basketball Betting Preview: Clemson vs West Virginia

The Clemson Tigers battle the West Virginia Mountaineers, with tip-off scheduled for 18:30 on Friday, November 21.

The best bet could involve backing West Virginia against the spread. There’s an attractive +3.5 available at -102 that they cover the line against Clemson and that has to be our prediction.

Clemson Tigers previous game saw them claim a 81-61 home win over North Alabama Lions.

West Virginia Mountaineers last game saw them claim a 81-59 home win over Lafayette Leopards.

Head-to-Head Statistics

West Virginia beat Clemson in their last head-to-head matchup. It was a 66-59 scoreline.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Clemson	24-10	2521	2269	252	16-3	8-7	1L
West Virginia	18-14	2214	2072	142	15-6	3-8	1L

View Full Standings

Clemson vs West Virginia Prediction & Picks

From our main match prediction to correct score advice, must-watch player props and a custom bet builder — this Clemson vs West Virginia betting preview covers it all.

Game Prediction

We’re confident that West Virginia can either win or suffer a narrow defeat in this college matchup. That makes the underdogs at +3.5 the best pick and odds of -102 are available.

We closely track recent form and look for patterns that may impact the outcome. The same goes for injuries to key players. When combined with the most relevant college hoops stats, this gives us a strong foundation for accurate basketball picks.

Key Clemson vs West Virginia stats:

• The +3.5 line has been covered by WVU in 5 consecutive games.
• The +3.5 line has been covered by WVU in 8 of their last 10 games.
• The +3.5 line has been covered by WVU in 15 of their last 20 games at home.
• The -3.5 line hasn’t been covered by Clemson in 2 consecutive games on the road.

WVU +3.5 Probability

The top sportsbooks make it a 50.5% chance that our pick is settled as a winner. Based on our analysts in-depth research, we calculate the actual probability to be 55-60%. This is why we regard this as a value wager.

If you want to pimp the odds about WVU covering the line, you might consider going down the Bet Builder route and combine this prediction with other selections.

Start your betting journey with value. Our guide features the best free bets and sign-up bonuses available today.

Our Game Prediction

West Virginia +3.5 @ -102 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Nov 20, 22:55). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Brenen Lorient Over 10.5 Points -105

Brenen Lorient (West Virginia) can be backed to register Over 10.5 points at -105. We’ve found an opportunity to bet on Player Points where we’re able to back him to cover the line.

Latest Brenen Lorient Player Prop Odds

Points

Over 10.5

-105

Under 10.5

-125

Assists

Over 1.5

-118

Under 1.5

-110

Rebounds

Over 7.5

-105

Under 7.5

-125

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Harlan Obioha Over 8.5 Points -125

Harlan Obioha (West Virginia) can be wagered to score Over 8.5 points at -125. We have a strong conviction that he is able to cover the total when it comes to betting on Player Points.

Latest Harlan Obioha Player Prop Odds

Points

Over 8.5

-125

Under 8.5

-105

Assists

Over 0.5

-222

Under 0.5

+165

Rebounds

Over 5.5

-141

Under 5.5

+105

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Clemson 69 - 71 West Virginia

A close game could be on the cards. We’ll bet on the Mountaineers to secure a 71-69 win at huge odds and this correct score selection should hopefully be a fun one.

T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Clemson vs West Virginia Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Clemson are +146 favorites and that means a 41% chance of winning this college game according to the Moneyline betting odds with the sportsbooks. The market suggests that West Virginia are least likely to win at -175.

The spread is 3.5 and the total points line is currently 133.5. Having a wager on the Totals is one of the most popular basketball bets. If you’re wanting to back Over 133.5, the odds are -112.

College basketball bettors are spoilt for choice thanks to the huge selection of game lines and team props which are available for most matchups on the coupon. Head to the top betting apps and find the best value picks.

Moneyline

Clemson

+146

WVU

-175

Point Spread

Clemson +3.5

-110

WVU -3.5

-110

Total Points

Under 133.5

-108

Over 133.5

-112

Honor Huff is favorite when it comes to landing the most baskets. You can get -105 that he goes Over 14.5 points and -125 when it comes to Under.

Honor Huff (WVU)

Over 14.5

-105

Under 14.5

-125

Brenen Lorient (WVU)

Over 10.5

-105

Under 10.5

-125

Jasper Floyd (WVU)

Over 9.5

-115

Under 9.5

-115

Harlan Obioha (WVU)

Over 8.5

-125

Under 8.5

-105

Jake Wahlin (Clemson)

Over 8.5

+105

Under 8.5

-141

Treysen Eaglestaff (WVU)

Over 6.5

-110

Under 6.5

-120

Jasper Floyd (WVU)

Over 4.5

+105

Under 4.5

-135

Brenen Lorient (WVU)

Over 1.5

-118

Under 1.5

-110

Honor Huff (WVU)

Over 0.5

-164

Under 0.5

+130

Harlan Obioha (WVU)

Over 0.5

-222

Under 0.5

+165

Jake Wahlin (Clemson)

Over 0.5

-222

Under 0.5

+165

Treysen Eaglestaff (WVU)

Over 0.5

-189

Under 0.5

+140

Brenen Lorient (WVU)

Over 7.5

-105

Under 7.5

-125

Harlan Obioha (WVU)

Over 5.5

-141

Under 5.5

+105

Jake Wahlin (Clemson)

Over 5.5

+115

Under 5.5

-149

Jasper Floyd (WVU)

Over 3.5

-135

Under 3.5

-100

Treysen Eaglestaff (WVU)

Over 3.5

-141

Under 3.5

+110

Honor Huff (WVU)

Over 2.5

+110

Under 2.5

-149

For those looking to enjoy a thrilling in-game wager, college basketball micro betting could be up your street. You are now able to wager on the Next Field Goal, with the options being for a two-pointer or a three-pointer.

Latest regular season and playoff games stats.

Clemson Stats

West Virginia Stats

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 8 wins and 2 defeats in the last 10 games on the road

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 8 wins and 2 defeats in the last 10 home games

Point Spread

• -3.5 Betting Line: Have covered the spread in 6 of the last 10 games
• -3.5 Betting Line on the Road: Have covered the spread in 7 of the last 10 games on the road

Point Spread

• +3.5 Betting Line: Have covered the spread in 8 of the last 10 games
• +3.5 Betting Line at Home: Have covered the spread in 8 of the last 10 home games

Total Points

• Game Totals: An average of 137.10 pts in the previous 10 games
• Game Totals on the Road: An average of 138.10 pts in the previous 10 games on the road
• Over 133.5: Covered in 7 of the previous 10 games
• Over 133.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 76.30 pts and allowed 60.80 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 73.50 pts and allowed 64.60 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 130.30 pts in the previous 10 games
• Game Totals at Home: An average of 129.30 pts in the previous 10 home games
• Over 133.5: Covered in 4 of the previous 10 games
• Over 133.5 at Home: Covered in 4 of the previous 10 home games
• Team Totals: Have scored an average of 69.60 pts and allowed 60.70 pts in the last 10 games
• Team Totals at Home: Have scored an average of 70.00 pts and allowed 59.30 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big 12	Overall	PF	PA	N. Pts	Home	Away	Strk
Arizona	32-2	2929	2339	590	21-1	11-1	9W
Houston	28-6	2623	2137	486	20-2	8-4	1L
Iowa State	27-7	2781	2215	566	19-1	8-6	1L
Kansas	23-10	2496	2290	206	17-2	6-8	1L
Texas Tech	22-10	2573	2324	249	16-4	6-6	3L
BYU	23-11	2853	2561	292	17-4	6-7	1L
TCU	22-11	2584	2378	206	16-5	6-6	1L
UCF	21-11	2591	2511	80	15-5	6-6	1L
Oklahoma State	19-14	2781	2736	45	14-5	5-9	1L
West Virginia	18-14	2214	2072	142	15-6	3-8	1L
Cincinnati	18-15	2413	2230	183	16-4	2-11	1L
Colorado	17-15	2559	2542	17	15-7	2-8	2L
Arizona State	17-16	2519	2585	-66	13-6	4-10	1L
Baylor	16-16	2642	2469	173	12-8	4-8	1L
Kansas State	12-20	2546	2619	-73	11-8	1-12	2L
Utah	10-22	2379	2531	-152	9-9	1-13	6L

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	32-2	2798	2147	651	21-0	11-2	11W
Virginia	29-5	2742	2326	416	19-1	10-4	1L
Miami	25-8	2704	2349	355	16-4	9-4	1L
North Carolina	24-8	2553	2282	271	19-1	5-7	2L
Clemson	24-10	2521	2269	252	16-3	8-7	1L
Louisville	23-10	2797	2382	415	16-2	7-8	1L
California	21-11	2492	2344	148	17-4	4-7	2L
Stanford	20-12	2431	2326	105	12-7	8-5	1L
NC State	20-13	2762	2525	237	13-7	7-6	1L
SMU	20-13	2779	2561	218	17-3	3-10	1L
Virginia Tech	19-13	2521	2396	125	15-4	4-9	2L
Florida State	18-15	2652	2572	80	12-8	6-7	1L
Wake Forest	17-16	2602	2543	59	12-6	5-10	1L
Syracuse	15-17	2400	2376	24	12-6	3-11	6L
Notre Dame	13-18	2308	2335	-27	11-7	2-11	2L
Pittsburgh	13-20	2327	2370	-43	8-10	5-10	1L
Boston College	11-20	2090	2191	-101	10-10	1-10	1W
Georgia Tech	11-20	2287	2400	-113	10-10	1-10	12L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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