Louisville vs Indiana Prediction, Picks & Odds | 06 Dec 2025
College Basketball Betting Preview: Louisville vs Indiana
The Louisville Cardinals face the Indiana Hoosiers, with tip-off scheduled for 14:15 on Saturday, December 6.
Let’s shoot for a total bet between Louisville and Indiana, with Under 157.5 points available at odds of -105. This betting prediction has plenty of juice in the price.
Louisville Cardinals were defeated in their previous game. On the road, they suffered a 89-80 reverse against Arkansas Razorbacks.
Indiana Hoosiers were defeated in their last game. On the road, they suffered a 73-64 reverse against Minnesota Golden Gophers.
Head-to-Head Statistics
Louisville triumphed 89-61 when they last played Indiana. It’s been two Indiana wins in the past 3 games between these teams.
| NCAAB | Overall | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|
Louisville
|
23-10 | 2797 | 2382 | 415 | 16-2 | 7-8 | 1L |
Indiana
|
18-14 | 2501 | 2309 | 192 | 15-6 | 3-8 | 2L |
Louisville vs Indiana Prediction & Picks
We dive into the best Louisville vs Indiana betting angles, including an expert match prediction, correct score forecast, top player prop bets and a value-focused bet builder.
Game Prediction
The -105 about Under 157.5 points makes lots of appeal. We’re not sure that the teams can combine to reach that number for this college matchup.
We track all injuries that could impact each team before making our basketball picks. The form guide and latest stats also help the Sportsgambler.com team crunch the numbers ahead of the college hoops action.
Key Louisville vs Indiana stats:
Under 157.5 Probability
The best sportsbooks are estimating that there is a 51.3% likelihood of this pick delivering a return. In the opinion of our analysts, there’s actually a probability of success closer to 60%. It’s why we think it’s worth placing this college basketball wager.
More juice from your Unders wager can be found by combining this selection on the Match Result & Total lines. Choose the odds which match your prediction.
Don’t place another bet without seeing the best betting offers available—free bets and welcome promos included.
Player Prop Picks
Isaac McKneely (Louisville) is available at +180 to record Under 0.5 assists. There’s no reason to oppose our instinct, so we’ll bet on him failing to cover the Player Assists total here.
Latest Isaac McKneely Player Prop Odds
Tucker DeVries (Indiana) can be backed to have Under 5.5 rebounds at -154. There’s every chance that he will go Under as we’re confident he’ll fail to cover the Player Rebounds line.
Latest Tucker DeVries Player Prop Odds
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Picks
We’ve compiled a same game parlay that includes Under 161.5, combined with Indiana +4.5 on the spread and Isaac McKneely (Louisville) to get Under 0.5 assists.
There are many options when you place a same game parlay. You can go through the available basketball lines and identify your favorite picks before combining the odds on the bet slip. Personalised wagering doesn’t come any better.
Correct Score Prediction
77
-
75
Indiana
We’ll roll the dice and go for Louisville to register a 77-75 victory. We don’t think that there will be too much between the teams and we’re happy to take the massive odds.
Louisville vs Indiana Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
For this college game, the sportsbooks’ Moneyline betting odds mean Louisville are -169 favorites to win and that means a 63% chance of landing a victory. Indiana are trading at bigger odds than their opponents and they can be backed at +140.
3.5 is where the spread lies, with total points being 161.5 right now. A Total bet is always available and can often provide value selections. If you want to bet Under 161.5, there are odds of -105.
You can find a nice selection of game lines and team props for most college basketball matchups, with the top betting apps creating many different options. Check out the pre-game and in-game selections before placing your bets.
Ryan Conwell is favorite when it comes to hitting the most buckets. You can get -105 that he goes Over 19.5 points and -123 when it comes to Under.
An increasing number of bettors are now enjoying micro betting on college basketball and it’s something which is available on an in-game basis. Wait for the action to start and then wager on something specific to happen.
Latest regular season and playoff games stats.
Louisville Stats
Indiana Stats
- 7 wins and 3 defeats in the last 10 games
- 7 wins and 3 defeats in the last 10 games on the road
- -5.5 Betting Line: Have covered the spread in 7 of the last 10 games
- -5.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road
- +5.5 Betting Line: Have covered the spread in 8 of the last 10 games
- +5.5 Betting Line at Home: Have covered the spread in the last 10 home games
- Game Totals: An average of 158.60 pts in the previous 10 games
- Game Totals on the Road: An average of 147.70 pts in the previous 10 games on the road
- Over 157.5: Covered in 5 of the previous 10 games
- Over 157.5 on the Road: Covered in 2 of the previous 10 games on the road
- Team Totals: Have scored an average of 89.40 pts and allowed 69.20 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 79.00 pts and allowed 68.70 pts in the last 10 games on the road
- Game Totals: An average of 145.80 pts in the previous 10 games
- Game Totals at Home: An average of 148.20 pts in the previous 10 home games
- Over 157.5: Covered in 2 of the previous 10 games
- Over 157.5 at Home: Covered in 3 of the previous 10 home games
- Team Totals: Have scored an average of 81.60 pts and allowed 64.20 pts in the last 10 games
- Team Totals at Home: Have scored an average of 84.90 pts and allowed 63.30 pts in the last 10 home games
NCAAB Table Select Season
| Big Ten | Overall | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|
Michigan
|
31-3 | 2952 | 2353 | 599 | 19-2 | 12-1 | 1L |
Nebraska
|
26-6 | 2473 | 2119 | 354 | 19-3 | 7-3 | 1L |
Michigan State
|
25-7 | 2526 | 2189 | 337 | 17-3 | 8-4 | 2L |
Purdue
|
27-8 | 2858 | 2455 | 403 | 16-5 | 11-3 | 4W |
Illinois
|
24-8 | 2700 | 2234 | 466 | 15-6 | 9-2 | 1L |
Wisconsin
|
24-10 | 2822 | 2581 | 241 | 16-2 | 8-8 | 1L |
UCLA
|
23-11 | 2643 | 2414 | 229 | 18-3 | 5-8 | 1L |
Ohio State
|
21-12 | 2633 | 2402 | 231 | 15-5 | 6-7 | 1L |
Iowa
|
21-12 | 2482 | 2177 | 305 | 17-3 | 4-9 | 1L |
|
Indiana
|
18-14 | 2501 | 2309 | 192 | 15-6 | 3-8 | 2L |
USC
|
18-14 | 2515 | 2494 | 21 | 11-7 | 7-7 | 8L |
Washington
|
16-17 | 2545 | 2430 | 115 | 11-6 | 5-11 | 1L |
Minnesota
|
15-17 | 2241 | 2193 | 48 | 13-8 | 2-9 | 1L |
Northwestern
|
15-19 | 2487 | 2447 | 40 | 11-9 | 4-10 | 1L |
Rutgers
|
14-19 | 2329 | 2479 | -150 | 11-7 | 3-12 | 1L |
Oregon
|
12-20 | 2267 | 2366 | -99 | 10-10 | 2-10 | 1L |
Penn State
|
12-20 | 2358 | 2539 | -181 | 10-10 | 2-10 | 3L |
Maryland
|
12-21 | 2300 | 2527 | -227 | 9-8 | 3-13 | 1L |
| Atlantic Coast | Overall | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|
Duke
|
32-2 | 2798 | 2147 | 651 | 21-0 | 11-2 | 11W |
Virginia
|
29-5 | 2742 | 2326 | 416 | 19-1 | 10-4 | 1L |
Miami
|
25-8 | 2704 | 2349 | 355 | 16-4 | 9-4 | 1L |
North Carolina
|
24-8 | 2553 | 2282 | 271 | 19-1 | 5-7 | 2L |
Clemson
|
24-10 | 2521 | 2269 | 252 | 16-3 | 8-7 | 1L |
|
Louisville
|
23-10 | 2797 | 2382 | 415 | 16-2 | 7-8 | 1L |
California
|
21-11 | 2492 | 2344 | 148 | 17-4 | 4-7 | 2L |
Stanford
|
20-12 | 2431 | 2326 | 105 | 12-7 | 8-5 | 1L |
NC State
|
20-13 | 2762 | 2525 | 237 | 13-7 | 7-6 | 1L |
SMU
|
20-13 | 2779 | 2561 | 218 | 17-3 | 3-10 | 1L |
Virginia Tech
|
19-13 | 2521 | 2396 | 125 | 15-4 | 4-9 | 2L |
Florida State
|
18-15 | 2652 | 2572 | 80 | 12-8 | 6-7 | 1L |
Wake Forest
|
17-16 | 2602 | 2543 | 59 | 12-6 | 5-10 | 1L |
Syracuse
|
15-17 | 2400 | 2376 | 24 | 12-6 | 3-11 | 6L |
Notre Dame
|
13-18 | 2308 | 2335 | -27 | 11-7 | 2-11 | 2L |
Pittsburgh
|
13-20 | 2327 | 2370 | -43 | 8-10 | 5-10 | 1L |
Boston College
|
11-20 | 2090 | 2191 | -101 | 10-10 | 1-10 | 1W |
Georgia Tech
|
11-20 | 2287 | 2400 | -113 | 10-10 | 1-10 | 12L |
- Overall = Overall Wins-Losses
- PF = Total Points For
- PA = Total Points Against
- N. Pts = Point Differential
- Home = Home Record
- Away = Away Record
- Strk = Current Streak
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