Michigan vs Duke Prediction, Picks & Odds | 21 Feb 2026

College Basketball Betting Preview: Michigan vs Duke

The Michigan Wolverines go up against the Duke Blue Devils, with tip-off scheduled for 18:30 on Saturday, February 21.

We’ll take a chance on Duke who have been given an appealing +3.5 on the spread. We think -120 can be taken with confidence that they cover the line against Michigan.

Michigan Wolverines triumphed in their previous game. It was on the road where Purdue Boilmakers were beaten 91-80.

Duke Blue Devils were winners last time out. It was a 101-64 home victory against Syracuse Orange.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Michigan	25-1	2356	1788	568	15-1	10-0	11W
Duke	24-2	2157	1642	515	15-0	9-2	3W

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Michigan vs Duke Prediction & Picks

Gear up for Michigan vs Duke with our betting guide, featuring an expert match prediction, scoreline advice and a hand-picked bet builder. Explore each section below for detailed insights.

Game Prediction

We’re confident that Duke can either win or suffer a narrow defeat in this college matchup. That makes the underdogs at +3.5 the best pick and odds of -120 are available.

Incoming team news often impacts the betting lines and odds in significant ways. Our college hoops handicappers factor this in alongside recent form, while key stats are also carefully weighed to strengthen each basketball pick.

Key Michigan vs Duke stats:

• The +3.5 line has been covered by Duke in 20 consecutive games at home.

Duke +3.5 Probability

According to the top betting apps, there’s a 54.6% likelihood of our pick delivering a return. However, we have this number closer to 60% based on our in-depth research. This is why we can recommend this college basketball wager.

There’s often the option to sell points and that allows you to leverage a bigger potential return. Conversely, buying points will give you a less-risky bet but smaller odds.

Thinking about claiming free bets? Our bonus guide lists the best sign-up offers from the biggest names in betting.

Our Game Prediction

Duke +3.5 @ -120 Bet Now

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Correct Score Prediction

Michigan 71 - 74 Duke

Duke are available at massive odds to register a 74-71 victory and they might have the edge. This should be a close game and there won’t be much between the teams.

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Michigan vs Duke Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The sportsbooks’ betting odds have Michigan as -172 favorites for this college game, implying that they are 63% likely to win. Duke are regarded as a long shot to win and you can currently back them at +142.

The spread is calculated to be 3.5, while total points comes in at 150.5. A bet on the Totals allows fans to use the latest basketball data to good effect. If you want to bet Under 150.5, there are odds of -110.

The best betting sites offer stacks of team props and game lines when it comes to most college basketball contests. Make sure you look through all the available options before deciding which bet to place.

Moneyline

Michigan

-172

Duke

+142

Point Spread

Michigan -3.5

-102

Duke +3.5

-120

Total Points

Under 150.5

-110

Over 150.5

-110

Should you be more interested in a specific individual who is competing, check out the gambling sites’ prop bets where you can pick out player lines that focus on performance rather than the game result.

An increasing number of bettors are now enjoying micro betting on college basketball and it’s something which is available on an in-game basis. Wait for the action to start and then wager on something specific to happen.

Latest regular season and playoff games stats.

Michigan Stats

Duke Stats

Moneyline

• 10 wins and 0 defeats in the last 10 games
• 10 wins and 0 defeats in the last 10 games on the road

Moneyline

• 9 wins and 1 defeat in the last 10 games
• 10 wins and 0 defeats in the last 10 home games

Point Spread

• -3.5 Betting Line: Have covered the spread in 9 of the last 10 games
• -3.5 Betting Line on the Road: Have covered the spread in 9 of the last 10 games on the road

Point Spread

• +3.5 Betting Line: Have covered the spread in the last 10 games
• +3.5 Betting Line at Home: Have covered the spread in the last 10 home games

Total Points

• Game Totals: An average of 154.40 pts in the previous 10 games
• Game Totals on the Road: An average of 157.00 pts in the previous 10 games on the road
• Over 149.5: Covered in 6 of the previous 10 games
• Over 149.5 on the Road: Covered in 7 of the previous 10 games on the road
• Team Totals: Have scored an average of 85.50 pts and allowed 68.90 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 85.00 pts and allowed 72.00 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 134.60 pts in the previous 10 games
• Game Totals at Home: An average of 146.90 pts in the previous 10 home games
• Over 149.5: Covered in 2 of the previous 10 games
• Over 149.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 76.90 pts and allowed 57.70 pts in the last 10 games
• Team Totals at Home: Have scored an average of 83.20 pts and allowed 63.70 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	24-2	2157	1642	515	15-0	9-2	3W
Virginia	23-3	2129	1753	376	13-1	10-2	7W
Miami	21-5	2156	1818	338	14-3	7-2	4W
North Carolina	20-6	2103	1843	260	16-0	4-6	1L
Clemson	20-7	2022	1767	255	13-2	7-5	3L
Louisville	19-7	2257	1868	389	13-2	6-5	1L
NC State	19-8	2291	1992	299	12-5	7-3	1W
SMU	18-8	2250	2024	226	15-2	3-6	1W
California	18-8	2053	1897	156	15-3	3-5	1W
Virginia Tech	17-10	2124	2010	114	13-3	4-7	2L
Stanford	16-10	1961	1886	75	10-6	6-4	1L
Syracuse	15-12	2053	1977	76	12-4	3-8	1L
Wake Forest	14-12	2077	2002	75	10-6	4-6	3W
Florida State	13-13	2089	2032	57	10-7	3-6	2W
Notre Dame	12-14	1941	1909	32	10-5	2-9	1W
Georgia Tech	11-16	2005	2078	-73	10-8	1-8	8L
Pittsburgh	9-17	1818	1866	-48	7-9	2-8	5L
Boston College	9-17	1758	1813	-55	8-10	1-7	7L

Big Ten	Overall	PF	PA	N. Pts	Home	Away	Strk
Michigan	25-1	2356	1788	568	15-1	10-0	11W
Nebraska	22-4	2036	1706	330	16-2	6-2	1L
Illinois	22-5	2290	1838	452	14-4	8-1	2W
Purdue	22-5	2239	1870	369	15-3	7-2	1W
Michigan State	21-5	2052	1726	326	15-2	6-3	1W
Iowa	19-7	1981	1674	307	15-2	4-5	1W
Wisconsin	18-8	2161	1976	185	13-2	5-6	1L
USC	18-8	2097	1997	100	11-4	7-4	2L
UCLA	17-9	2007	1844	163	14-2	3-7	2L
Ohio State	17-9	2110	1908	202	12-5	5-4	1W
Indiana	17-10	2153	1948	205	14-3	3-7	2L
Washington	13-13	1998	1883	115	9-5	4-8	1W
Minnesota	12-14	1835	1767	68	10-7	2-7	1W
Rutgers	11-15	1835	1963	-128	10-6	1-9	2W
Northwestern	11-16	2002	1972	30	9-8	2-8	1W
Penn State	11-16	2033	2139	-106	9-9	2-7	2L
Maryland	10-16	1859	2033	-174	8-6	2-10	2L
Oregon	9-17	1850	1933	-83	8-9	1-8	1L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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