Old Dominion vs Southern Miss Prediction, Picks & Odds | 21 Feb 2026

College Basketball Betting Preview: Old Dominion vs Southern Miss

The Old Dominion Monarchs square off against the Southern Miss Golden Eagles, with tip-off scheduled for 15:00 on Saturday, February 21.

If you agree that Old Dominion can push Southern Miss to the wire, then bet the underdogs against the spread here. The +3.5 makes plenty of appeal at odds of -105.

Old Dominion Monarchs claimed a victory in their previous game. A 83-72 home win occurred against Louisiana Ragin' Cajuns.

Southern Miss Golden Eagles won their last game, beating Troy Trojans at home. It was a 69-65 win.

Head-to-Head Statistics

It was Old Dominion who came out on top when they last played Southern Miss. A 74-71 win was recorded. The past 7 clashes between these teams have seen five Old Dominion wins.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Southern Miss	14-14	2054	2052	2	11-3	3-11	1W
Old Dominion	10-18	2093	2146	-53	7-6	3-12	2W

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Old Dominion vs Southern Miss Prediction & Picks

This Old Dominion vs Southern Miss betting guide features sharp analysis across major markets, including an expert match prediction, correct score bet and a strategic bet builder.

Game Prediction

There’s a great opportunity to back Old Dominion against the spread considering they should perform well in this college contest. Snap up the -105 when it comes to the underdogs covering the +3.5.

We use the latest team news and injury updates to help shape the best possible basketball predictions. You’ll also notice we take a stats-led approach by factoring in the key college hoops numbers that truly make a difference.

Key Old Dominion vs Southern Miss stats:

• The +3.5 line has been covered by Old Dominion in 4 consecutive games.
• The +3.5 line has been covered by Old Dominion in 7 of their last 10 games.
• The +3.5 line has been covered by Old Dominion in 11 of their last 20 games.
• The -3.5 line hasn’t been covered by Southern Miss in 8 of their last 10 games.
• The -3.5 line hasn’t been covered by Southern Miss in 12 of their last 20 games.
• The -3.5 line hasn’t been covered by Southern Miss in 5 of their last 7 games against Old Dominion.

Old Dominion +3.5 Probability

Based on the latest odds from the top sportsbooks, our pick carries a 51.3% chance of winning. Taking all factors into consideration, our analysts think there’s a stronger chance of success and have a probability interval between 55-60%. The bet can be recommended for this precise reason.

Selling points can be a great alternative and allows bettors to enjoy a bigger return on the same selection. For a more conservative pick, you can alternatively buy points.

Thinking of placing a bet? Make sure to check our guide first — it’s full of the latest offers and welcome bonuses worth claiming.

Our Game Prediction

Old Dominion +3.5 @ -105 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Feb 20, 23:04). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Old Dominion 71 - 70 Southern Miss

There might not be too much between these teams, with our correct score pick being a 71-70 win for Old Dominion. There are huge odds available when it comes to this selection.

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Old Dominion vs Southern Miss Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Southern Miss are massive favorites for this college game, with some sportsbooks not even offering Moneyline wagering. Therefore, they’re available on the spread depending on what you expect the winning margin to be.

3.5 is where the spread lies, with total points being 147.5 right now. There is no denying the popularity of betting on the Totals. If you want to bet Under 147.5, there are odds of -108.

If you’re planning to place a bet on a college hoops matchup, visit the top basketball betting sites and check out the many available game lines and team props. Find the lines which are the most attractive.

Moneyline

Old Dominion

-

Southern Miss

-

Point Spread

Old Dominion +3.5

-105

Southern Miss -3.5

-115

Total Points

Under 147.5

-108

Over 147.5

-112

As an alternative to the game lines and team props, check out the player props that are available. These can be a great alternative if you want to focus on a player’s performance. The best gambling sites will provide lots of options.

It’s possible to use stats to your advantage when it comes to college basketball micro betting, especially if you’re predicting outcomes such as the Next Field Goal. Check out the live player, score and team props to see if you can find an angle.

Latest regular season and playoff games stats.

Old Dominion Stats

Southern Miss Stats

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 3 wins and 7 defeats in the last 10 games on the road

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +3.5 Betting Line: Have covered the spread in 7 of the last 10 games
• +3.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• -3.5 Betting Line: Have covered the spread in 2 of the last 10 games
• -3.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games

Total Points

• Game Totals: An average of 153.20 pts in the previous 10 games
• Game Totals on the Road: An average of 147.60 pts in the previous 10 games on the road
• Over 147.5: Covered in 7 of the previous 10 games
• Over 147.5 on the Road: Covered in 4 of the previous 10 games on the road
• Team Totals: Have scored an average of 77.20 pts and allowed 76.00 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 70.80 pts and allowed 76.80 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 143.60 pts in the previous 10 games
• Game Totals at Home: An average of 140.10 pts in the previous 10 home games
• Over 147.5: Covered in 4 of the previous 10 games
• Over 147.5 at Home: Covered in 3 of the previous 10 home games
• Team Totals: Have scored an average of 68.70 pts and allowed 74.90 pts in the last 10 games
• Team Totals at Home: Have scored an average of 71.50 pts and allowed 68.60 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Sun Belt	Overall	PF	PA	N. Pts	Home	Away	Strk
South Alabama	19-9	2093	1964	129	10-3	9-6	2L
Troy	18-10	2282	2092	190	8-4	10-6	1W
Marshall	18-10	2264	2149	115	12-3	6-7	2W
Appalachian State	18-11	2086	1894	192	11-4	7-7	2L
Texas State	18-11	2174	2066	108	15-2	3-9	7W
Arkansas State	17-11	2306	2155	151	9-4	8-7	1W
Coastal Carolina	16-12	2050	2013	37	7-5	9-7	1L
Georgia Southern	15-13	2254	2223	31	9-6	6-7	1L
James Madison	15-13	2063	2079	-16	11-3	4-10	4W
Southern Miss	14-14	2054	2052	2	11-3	3-11	1W
Georgia State	10-18	1969	2070	-101	7-5	3-13	1W
Old Dominion	10-18	2093	2146	-53	7-6	3-12	2W
Louisiana	9-19	1761	1957	-196	6-8	3-11	3L
UL Monroe	4-24	2025	2327	-302	3-11	1-13	4L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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