Santa Clara vs Saint Louis Prediction, Picks & Odds | 27 Nov 2025

College Basketball Betting Preview: Santa Clara vs Saint Louis

The Santa Clara Broncos go up against the Saint Louis Billikens, with tip-off scheduled for 19:00 on Thursday, November 27.

There’s merit in backing Santa Clara on the Moneyline considering our prediction is that the road team will have the edge over Saint Louis. Especially as +105 is on offer about this happening.

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Saint Louis Billikens won their previous game which was at home. It was a 91-60 triumph against Purdue Fort Wayne Mastodons.

Santa Clara Broncos won their last game, beating Louisiana Ragin' Cajuns at home. It was a 80-43 win.

Head-to-Head Statistics

The last head-to-head saw Santa Clara claim a 85-78 win over Saint Louis.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Saint Louis	5-0	478	343	135	5-0	0-0	5W
Santa Clara	6-0	491	369	122	5-0	1-0	6W

View Full Standings

Santa Clara vs Saint Louis Prediction & Picks

We dive into the top Santa Clara vs Saint Louis betting angles, including our main match prediction, best correct score play and a bet builder tailored for value.

Game Prediction

There’s a juicy +105 that Santa Clara are able to get the better of their opponents. This value pick can be wagered on the Moneyline for this college showdown.

Tracking injury updates is a big part of our college hoops analysis and team news plays a major role in shaping our basketball picks. We combine this with recent form and the most important stats to get a complete picture.

Key Santa Clara vs Saint Louis stats:

• Santa Clara have won 6 consecutive games.
• Santa Clara have won 8 of their last 10 games.
• Santa Clara have won 14 of their last 20 games.

Santa Clara Moneyline Probability

When you look at the latest odds, our pick has a 48.8% chance of landing a return. However, we have this number between 55-60% based on our in-depth research. It’s the reason why we are recommending this college basketball bet.

If you can correctly predict that Santa Clara will win along with the number of points, then you are able to combine the two options and getting larger odds on the Match Result & Total market.

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Our Game Prediction

Santa Clara Moneyline @ +105 Bet Now

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Correct Score Prediction

Santa Clara 79 - 76 Saint Louis

We’ll roll the dice and go for Santa Clara to register a 79-76 victory. We don’t think that there will be too much between the teams and we’re happy to take the massive odds.

Santa Clara vs Saint Louis Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

You can choose Saint Louis at -130 or alternatively Santa Clara who have betting odds of +108. This means the leading sportsbooks give the visiting team a 48% chance of success.

There is a spread of 1.5 and total points has a line of 159.5. There is no denying the popularity of betting on the Totals. If you fancy Under 159.5, then the odds are -112.

Consider every angle when placing your college hoops bets. The top basketball betting sites offer a huge selection of game lines and team props, and it’s all about finding a wager that fits your prediction of the game.

Moneyline

Santa Clara

+108

Saint Louis

-130

Point Spread

Santa Clara +1.5

-106

Saint Louis -1.5

-114

Total Points

Under 159.5

-112

Over 159.5

-108

The gambling sites will have player props available for each game. Check out the various betting odds and take a view on whether a player’s Total Points, Three-Pointers, Blocks or Steals will hit over or under a certain line.

There are some exciting college basketball micro betting lines that are created and they are available in-game. Among them are Next Field Goal, where you select if the shot will be a two or three-pointer. The long-ball option pays better, and in today’s game, you can never discount the three-pointer.

Latest regular season and playoff games stats.

Santa Clara Stats

Saint Louis Stats

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 9 wins and 1 defeat in the last 10 home games

Point Spread

• +1.5 Betting Line: Have covered the spread in 8 of the last 10 games
• +1.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road

Point Spread

• -1.5 Betting Line: Have covered the spread in 7 of the last 10 games
• -1.5 Betting Line at Home: Have covered the spread in 9 of the last 10 home games

Total Points

• Game Totals: An average of 151.20 pts in the previous 10 games
• Game Totals on the Road: An average of 160.70 pts in the previous 10 games on the road
• Over 159.5: Covered in 4 of the previous 10 games
• Over 159.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 84.90 pts and allowed 66.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 85.50 pts and allowed 75.20 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 161.60 pts in the previous 10 games
• Game Totals at Home: An average of 161.90 pts in the previous 10 home games
• Over 159.5: Covered in 4 of the previous 10 games
• Over 159.5 at Home: Covered in 4 of the previous 10 home games
• Team Totals: Have scored an average of 86.00 pts and allowed 75.60 pts in the last 10 games
• Team Totals at Home: Have scored an average of 90.40 pts and allowed 71.50 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic 10	Overall	PF	PA	N. Pts	Home	Away	Strk
Saint Louis	5-0	478	343	135	5-0	0-0	5W
George Mason	7-0	558	433	125	5-0	2-0	7W
Richmond	5-0	450	335	115	5-0	0-0	5W
George Washington	7-1	737	595	142	6-0	1-1	1L
Dayton	5-1	469	401	68	4-0	1-1	3W
Davidson	5-1	454	417	37	3-1	2-0	1L
St. Bonaventure	5-1	462	425	37	5-0	0-1	1L
Rhode Island	6-2	629	541	88	3-1	3-1	2W
Duquesne	5-2	618	562	56	5-1	0-1	1W
Fordham	4-2	466	361	105	4-1	0-1	2W
VCU	4-2	516	424	92	3-0	1-2	2W
La Salle	3-3	422	408	14	3-1	0-2	1W
Saint Joseph's	3-3	479	478	1	3-0	0-3	1W
Loyola Chicago	1-7	520	611	-91	1-5	0-2	7L

West Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Saint Mary's	7-0	592	412	180	6-0	1-0	7W
Santa Clara	6-0	491	369	122	5-0	1-0	6W
Gonzaga	7-1	726	536	190	5-0	2-1	1L
Loyola Marymount	7-1	659	517	142	4-1	3-0	1W
San Francisco	5-1	484	392	92	4-0	1-1	4W
Seattle	4-1	409	356	53	3-1	1-0	3W
Pacific	5-2	527	466	61	3-0	2-2	2W
Portland	5-3	668	633	35	5-2	0-1	1W
San Diego	3-3	444	433	11	3-2	0-1	2L
Pepperdine	3-4	548	536	12	3-2	0-2	2L
Oregon State	3-4	502	526	-24	3-3	0-1	4L
Washington State	3-5	643	654	-11	2-3	1-2	2L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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