Southern Illinois vs Northern Iowa Prediction, Picks & Odds | 21 Feb 2026

College Basketball Betting Preview: Southern Illinois vs Northern Iowa

The Southern Illinois Salukis face the Northern Iowa Panthers, with tip-off scheduled for 18:00 on Saturday, February 21.

Our best wager is that Northern Iowa are going to cover a generous -6.5 on the spread. You can get -110 that there’s a bigger margin of victory against Southern Illinois.

Southern Illinois Salukis triumphed in their previous game. It was on the road where Drake Bulldogs were beaten 66-61.

Northern Iowa Panthers got the win in their last game. A 81-60 triumph occurred on the road when meeting Indiana State Sycamores.

Head-to-Head Statistics

Southern Illinois have won two on the bounce against Northern Iowa. Both victories came at home by 73-49 and 65-50 scorelines. In the past 10 H2H meetings, Northern Iowa have won six.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Northern Iowa	18-10	1947	1712	235	12-3	6-7	2W
Southern Illinois	13-15	2067	1980	87	7-7	6-8	1W

View Full Standings

Southern Illinois vs Northern Iowa Prediction & Picks

We cover the key Southern Illinois vs Northern Iowa betting angles, showcasing our expert match prediction, correct score selection and a bet builder tailored for the best value.

Game Prediction

Our best pick is that Northern Iowa will gain the upper hand in this college game. This leads us to back the favorites against the spread at -110, with the -6.5 line offering plenty of appeal.

The college hoops handicappers at Sportsgambler.com always keep close tabs on team news as it develops. We also rely on recent form and key stats to help shape our basketball picks and guide the final call.

Key Southern Illinois vs Northern Iowa stats:

• The -6.5 line has been covered by UNI in 4 of their last 5 games.
• The -6.5 line has been covered by UNI in 13 of their last 20 games at home.
• The -6.5 line has been covered by UNI in 3 consecutive games at home.

UNI -6.5 Probability

The best betting apps make it a 52.4% chance that our pick is settled as a winner. However, we think that the probability sits between 55-60% taking all factors into consideration. This is why we regard this as a value bet.

It’s good to explore all avenues and you might prefer bigger odds about the selection you want to make. Go ahead and move the line until you’re happy with the price.

Start wagering with a boost! Find the best welcome bonuses in our complete and updated betting offers guide.

Our Game Prediction

Northern Iowa -6.5 @ -110 Bet Now

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Correct Score Prediction

Southern Illinois 60 - 69 Northern Iowa

There are lots of different ways to back the Panthers on the correct score betting and something like 69-60 in their favor might be along the right lines at massive odds.

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Southern Illinois vs Northern Iowa Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

For this college game, the sportsbooks’ Moneyline betting odds mean Northern Iowa are -323 favorites to win and that means a 76% chance of landing a victory. The market suggests that Southern Illinois are least likely to win at +255.

There is a spread of 6.5 and total points has a line of 132.5. A Total wager relates to the number of points that will be scored overall. Those that want to back Under 132.5 can find odds of -115 available.

If you’re betting on college basketball, it’s a good idea to visit the best sportsbooks and browse the wide range of game lines and team props available. You’ll have the option to place wagers both pre-game and in-game.

Moneyline

Southern Illinois

+255

UNI

-323

Point Spread

Southern Illinois +6.5

-110

UNI -6.5

-110

Total Points

Under 132.5

-115

Over 132.5

-105

The best gambling sites offer player prop betting to their customers. These can be a great alternative if you want to focus on an individual’s performance within a game and it often involves wagering over or under a line.

Instead of focusing on the overall outcome, some bettors prefer to look at the college basketball micro betting lines. As the name suggests, it means placing short-term in-game wagers and this might include Next Field Goal, with the options being for a two-pointer or a three-pointer.

Latest regular season and playoff games stats.

Southern Illinois Stats

Northern Iowa Stats

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 games on the road

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +6.5 Betting Line: Have covered the spread in 8 of the last 10 games
• +6.5 Betting Line on the Road: Have covered the spread in 8 of the last 10 games on the road

Point Spread

• -6.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -6.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games

Total Points

• Game Totals: An average of 134.60 pts in the previous 10 games
• Game Totals on the Road: An average of 142.40 pts in the previous 10 games on the road
• Over 132.5: Covered in 5 of the previous 10 games
• Over 132.5 on the Road: Covered in 6 of the previous 10 games on the road
• Team Totals: Have scored an average of 68.90 pts and allowed 65.70 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 70.80 pts and allowed 71.60 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 133.40 pts in the previous 10 games
• Game Totals at Home: An average of 134.20 pts in the previous 10 home games
• Over 132.5: Covered in 5 of the previous 10 games
• Over 132.5 at Home: Covered in 6 of the previous 10 home games
• Team Totals: Have scored an average of 70.30 pts and allowed 63.10 pts in the last 10 games
• Team Totals at Home: Have scored an average of 70.20 pts and allowed 64.00 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Missouri Valley	Overall	PF	PA	N. Pts	Home	Away	Strk
Belmont	24-4	2346	2032	314	13-2	11-2	2W
Murray State	19-10	2422	2304	118	13-3	6-7	2L
Bradley	18-10	2154	2034	120	14-3	4-7	1L
Illinois State	18-10	2140	1899	241	14-3	4-7	1W
Northern Iowa	18-10	1947	1712	235	12-3	6-7	2W
UIC	16-12	2111	1929	182	9-5	7-7	3W
Valparaiso	14-13	1907	1930	-23	11-4	3-9	2W
Southern Illinois	13-15	2067	1980	87	7-7	6-8	1W
Drake	12-17	2210	2181	29	7-11	5-6	7L
Indiana State	10-18	2088	2104	-16	7-7	3-11	4L
Evansville	6-21	1798	2033	-235	4-11	2-10	2L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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