Tennessee vs Iowa State Prediction, Picks & Odds | 27 Mar 2026
NCAA Tournament Sweet 16 Betting Preview: Tennessee vs Iowa State
The No. 6 Tennessee Volunteers go up against the No. 2 Iowa State Cyclones in this NCAA Tournament Sweet 16 Midwest Region matchup at the United Center in Chicago, with tip-off scheduled for 22:10 on Friday, March 27.
Tennessee and Iowa State should be able to accumulate enough points for our prediction to win. We’re forecasting Over 139.5 and odds of -108 are available for this outcome.
Tennessee (24-11, 4th in SEC) enter this matchup having made tournament history as the first team to defeat 30-win opponents in both the Round of 64 and the Round of 32. The Vols’ path to the Sweet 16 began with a dominant 78-56 opening-round win over the Miami-Ohio RedHawks, followed by a gritty 79-72 victory against the Virginia Cavaliers in the Second Round.
Iowa State (29-7, 3rd in Big 12) arrive in the Sweet 16 boasting one of the most explosive offenses in the field. The Cyclones kickstarted their tournament with a 108-74 blowout of the Tennessee State Tigers and maintained that high-scoring pace with a dominant 82-63 win over the Kentucky Wildcats in the Second Round.
Head-to-Head Statistics
Tennessee claimed a dominant 68-45 victory over Iowa State in their most recent meeting on January 29, 2022.
| NCAAB Regular Season | Overall | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|
Iowa State
|
27-7 | 2781 | 2215 | 566 | 19-1 | 8-6 | 1L |
Tennessee
|
22-11 | 2622 | 2289 | 333 | 16-5 | 6-6 | 1L |
Tennessee vs Iowa State Prediction & Picks
From our main match prediction to correct score advice, must-watch player props and a custom bet builder — this Tennessee vs Iowa State betting preview covers it all.
Game Prediction
We’ll take a chance on a total wager after finding that the line is set at a generous 139.5. Expect this number to be surpassed at -108 for this college matchup.
Recent form is always part of the equation and we combine it with team news as soon as it’s available. To deliver expert basketball predictions, our handicappers also analyze the latest college hoops stats to ensure we’re working with the best information possible.
Key Tennessee vs Iowa State stats:
Over 139.5 Probability
According to the best sportsbooks, there’s a 51.8% likelihood of our pick landing a return. After careful examination, our analysts have this probability close to 60%. It is the reason why we are recommending this college basketball wager.
It’s possible to increase the odds on your Over wager by combining it with other picks. A Bet Builder allows you to connect multiple outcomes of the same game within a single bet.
Take full advantage of our betting promo codes. Browse our up-to-date guide featuring top bonuses and exclusive offers.
Player Prop Picks
Tamin Lipsey (Iowa State) can be wagered to secure Over 5.5 assists at -133. There’s an opportunity to enjoy a Player Assists bet that he is able to cover an appealing line.
Latest Tamin Lipsey Player Prop Odds
J.P. Estrella (Tennessee) is available at -130 to rack up Under 6.5 rebounds. There is plenty of juice when it comes to going under the Player Rebounds line and it looks a bet worth having.
Latest J.P. Estrella Player Prop Odds
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Picks
Get in the game with a same game parlay. Our picks are Over 139.5 on the total, Iowa State to cover the -4.5 spread and Tamin Lipsey (Iowa State) to get Over 5.5 assists.
A basketball same game parlay is an awesome way of cheering on different selections within the same game. You can predict a number of outcomes and get bigger odds than a single wager. The odds can combine to great effect.
Correct Score Prediction
68
-
75
Iowa State
There are lots of different betting angles including the chance to back the Cyclones on the correct score lines. For example, a 75-68 victory in their favor is available at massive odds.
Tennessee vs Iowa State Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
The sportsbooks’ betting odds have Iowa State as -185 favorites for this college game, implying that they are 65% likely to win. Tennessee are regarded as a long shot to win and you can currently back them at +152.
There is a spread of 4.5 and total points has a line of 139.5. A bet on the Totals allows fans to use the latest basketball data to good effect. If you fancy Over 139.5, this outcome can be backed at -108.
Whether you are betting pre-game or in-game, you can feast on a wide range of team props and game lines at the top basketball sportsbooks. The selections are practically endless, and it’s fantastic to have so many options.
In terms of landing the most baskets, favorite Ja'Kobi Gillespie is available at -105 to rack up Over 19.5 points. If you want to go Under, then -123 is available.
Latest regular season and playoff games stats.
Tennessee Stats
Iowa State Stats
- Game Totals: An average of 143.80 pts in the previous 10 games
- Over 139.5: Covered in 6 of the previous 10 games
- Team Totals: Have scored an average of 75.30 pts and allowed 68.50 pts in the last 10 games
NCAAB Regular Season Table Select Season
| Big 12 | Overall | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|
Arizona
|
32-2 | 2929 | 2339 | 590 | 21-1 | 11-1 | 9W |
Houston
|
28-6 | 2623 | 2137 | 486 | 20-2 | 8-4 | 1L |
|
Iowa State
|
27-7 | 2781 | 2215 | 566 | 19-1 | 8-6 | 1L |
Kansas
|
23-10 | 2496 | 2290 | 206 | 17-2 | 6-8 | 1L |
Texas Tech
|
22-10 | 2573 | 2324 | 249 | 16-4 | 6-6 | 3L |
BYU
|
23-11 | 2853 | 2561 | 292 | 17-4 | 6-7 | 1L |
TCU
|
22-11 | 2584 | 2378 | 206 | 16-5 | 6-6 | 1L |
UCF
|
21-11 | 2591 | 2511 | 80 | 15-5 | 6-6 | 1L |
Oklahoma State
|
19-14 | 2781 | 2736 | 45 | 14-5 | 5-9 | 1L |
West Virginia
|
18-14 | 2214 | 2072 | 142 | 15-6 | 3-8 | 1L |
Cincinnati
|
18-15 | 2413 | 2230 | 183 | 16-4 | 2-11 | 1L |
Colorado
|
17-15 | 2559 | 2542 | 17 | 15-7 | 2-8 | 2L |
Arizona State
|
17-16 | 2519 | 2585 | -66 | 13-6 | 4-10 | 1L |
Baylor
|
16-16 | 2642 | 2469 | 173 | 12-8 | 4-8 | 1L |
Kansas State
|
12-20 | 2546 | 2619 | -73 | 11-8 | 1-12 | 2L |
Utah
|
10-22 | 2379 | 2531 | -152 | 9-9 | 1-13 | 6L |
| Southeastern | Overall | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|
Florida
|
26-7 | 2864 | 2376 | 488 | 18-3 | 8-4 | 1L |
Arkansas
|
26-8 | 3058 | 2723 | 335 | 20-3 | 6-5 | 5W |
Vanderbilt
|
26-8 | 2936 | 2557 | 379 | 15-3 | 11-5 | 1L |
Alabama
|
23-9 | 2935 | 2671 | 264 | 15-6 | 8-3 | 1L |
Georgia
|
22-10 | 2874 | 2533 | 341 | 15-6 | 7-4 | 1L |
|
Tennessee
|
22-11 | 2622 | 2289 | 333 | 16-5 | 6-6 | 1L |
Texas A&M
|
21-11 | 2807 | 2546 | 261 | 14-5 | 7-6 | 1L |
Missouri
|
20-12 | 2549 | 2411 | 138 | 15-4 | 5-8 | 3L |
Kentucky
|
21-13 | 2746 | 2510 | 236 | 16-6 | 5-7 | 1L |
Texas
|
18-14 | 2681 | 2458 | 223 | 13-7 | 5-7 | 3L |
Oklahoma
|
19-15 | 2813 | 2621 | 192 | 13-5 | 6-10 | 1L |
Auburn
|
17-16 | 2730 | 2620 | 110 | 14-6 | 3-10 | 1L |
LSU
|
15-17 | 2606 | 2512 | 94 | 10-9 | 5-8 | 4L |
Ole Miss
|
15-20 | 2656 | 2664 | -8 | 9-9 | 6-11 | 1L |
Mississippi State
|
13-19 | 2484 | 2618 | -134 | 9-10 | 4-9 | 6L |
South Carolina
|
13-19 | 2398 | 2447 | -49 | 11-8 | 2-11 | 1L |
- Overall = Overall Wins-Losses
- PF = Total Points For
- PA = Total Points Against
- N. Pts = Point Differential
- Home = Home Record
- Away = Away Record
- Strk = Current Streak
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