USC vs Iowa Prediction, Picks & Odds | 28 Jan 2026

College Basketball Betting Preview: USC vs Iowa

The USC Trojans go up against the Iowa Hawkeyes, with tip-off scheduled for 19:00 on Wednesday, January 28.

We’re really sweet on the big favorites who are -10.5 on the spread. Iowa should enjoy a huge victory against USC and cover the line at -105.

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USC Trojans won their previous game by a 73-71 scoreline. It was on the road against Wisconsin Badgers.

Iowa Hawkeyes last game saw them claim a 68-62 home win over Rutgers Scarlet Knights.

Head-to-Head Statistics

USC had the edge in the most recent matchup between these teams. They recorded a 99-89 win over Iowa.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
USC	15-5	1642	1509	133	9-3	6-2	1W
Iowa	14-5	1480	1185	295	12-1	2-4	2W

View Full Standings

USC vs Iowa Prediction & Picks

Step into USC vs Iowa with confidence as we bring you our main match prediction, projected scoreline and a custom-built bet builder. Dive into each section below for the latest insights.

Game Prediction

There’s a case for taking the -105 that Iowa can overcome the -10.5 in this college showdown. They should be capable of a sizeable win and that means we’re backing the favorites against the spread.

Our college basketball handicappers start by reviewing the latest team news for each team, followed by a close look at recent form. That information is then applied to the most relevant stats to reach a well-informed verdict.

Key USC vs Iowa stats:

• The -10.5 line has been covered by Iowa in 7 of their last 10 games at home.
• The -10.5 line has been covered by Iowa in 12 of their last 20 games.

Iowa -10.5 Probability

The latest odds at the best betting apps suggest our pick carries a 51.3% chance of winning. Our cappers think there’s a stronger chance of success and calculate the probability to be 55-60%. The bet can be recommended for this precise reason.

In the quest to secure bigger odds, there’s the possibility of moving the line. There are plenty of choices when it comes to doing this, so you can choose the option that suits you.

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Our Game Prediction

Iowa -10.5 @ -105 Bet Now

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Correct Score Prediction

USC 68 - 81 Iowa

There is a speculative wager that can be enjoyed on Iowa when it comes to the correct score lines. Taking them to win 81-68 should provide some entertainment.

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USC vs Iowa Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

With an estimated 86% chance of winning, the sportsbooks are taking no chances with their -625 betting odds about Iowa triumphing in this college game. If you’re looking for an alternative angle, USC are trading at +450.

The spread currently stands at 10.5 and the total points line is 141.5. Basketball bettors love the chance to get an alternative angle by going for a Total wager. If you want to back Over 141.5, it’s -110.

Consider every angle when placing your college hoops bets. The top basketball betting sites offer a huge selection of game lines and team props, and it’s all about finding a wager that fits your prediction of the game.

Moneyline

USC

+450

Iowa

-625

Point Spread

USC +10.5

-115

Iowa -10.5

-105

Total Points

Under 141.5

-110

Over 141.5

-110

If you have a view on Total Points, Three-Pointers, Assists, Double-Doubles or Triple-Doubles, then the player prop betting could be up your street. It’s a great way of wagering on individual performance.

It’s good to consider all wagering options when it comes to college basketball and micro betting can be an exciting way to get involved in the action. When everything goes in-game, consider whether the next shot will be a Two or a Three-pointer.

Latest regular season and playoff games stats.

USC Stats

Iowa Stats

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 games on the road

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 9 wins and 1 defeat in the last 10 home games

Point Spread

• +10.5 Betting Line: Have covered the spread in 8 of the last 10 games
• +10.5 Betting Line on the Road: Have covered the spread in 8 of the last 10 games on the road

Point Spread

• -10.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -10.5 Betting Line at Home: Have covered the spread in 7 of the last 10 home games

Total Points

• Game Totals: An average of 147.10 pts in the previous 10 games
• Game Totals on the Road: An average of 154.30 pts in the previous 10 games on the road
• Over 141.5: Covered in 6 of the previous 10 games
• Over 141.5 on the Road: Covered in 7 of the previous 10 games on the road
• Team Totals: Have scored an average of 74.70 pts and allowed 72.40 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 76.20 pts and allowed 78.10 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 138.30 pts in the previous 10 games
• Game Totals at Home: An average of 144.20 pts in the previous 10 home games
• Over 141.5: Covered in 4 of the previous 10 games
• Over 141.5 at Home: Covered in 7 of the previous 10 home games
• Team Totals: Have scored an average of 76.10 pts and allowed 62.20 pts in the last 10 games
• Team Totals at Home: Have scored an average of 83.50 pts and allowed 60.70 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big Ten	Overall	PF	PA	N. Pts	Home	Away	Strk
Nebraska	20-1	1690	1374	316	15-0	5-1	1L
Michigan	19-1	1817	1376	441	13-1	6-0	5W
Michigan State	18-2	1582	1255	327	13-1	5-1	6W
Illinois	17-3	1709	1366	343	11-3	6-0	9W
Purdue	17-4	1747	1454	293	13-2	4-2	3L
USC	15-5	1642	1509	133	9-3	6-2	1W
Iowa	14-5	1480	1185	295	12-1	2-4	2W
UCLA	14-6	1547	1382	165	12-1	2-5	2W
Wisconsin	14-6	1672	1506	166	10-2	4-4	1L
Ohio State	14-6	1644	1451	193	10-3	4-3	1W
Indiana	14-7	1695	1455	240	12-3	2-4	2W
Washington	11-9	1580	1465	115	8-3	3-6	1W
Minnesota	10-10	1441	1370	71	9-6	1-4	5L
Rutgers	9-11	1394	1490	-96	9-4	0-7	3L
Northwestern	9-11	1530	1434	96	7-6	2-5	1L
Penn State	9-11	1532	1555	-23	8-7	1-4	7L
Oregon	8-12	1462	1483	-21	7-6	1-6	6L
Maryland	8-12	1459	1580	-121	7-4	1-8	2L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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