Drake vs Southern Illinois Prediction, Picks & Odds | 14 Jan 2026

College Basketball Betting Preview: Drake vs Southern Illinois

The Drake Bulldogs go up against the Southern Illinois Salukis, with tip-off scheduled for 21:00 on Wednesday, January 14.

We’re bullish about Southern Illinois on the spread at -5.5. They should be able to win by a comfortable margin against Drake and you can get -115.

Drake Bulldogs lost their previous game, being beaten at home to Belmont Bruins 78-76.

Southern Illinois Salukis suffered a defeat in their last game. A 70-57 scoreline occurred on the road against UIC Flames.

Head-to-Head Statistics

The scoreline was 70-53 in favor of Drake when they last played Southern Illinois. Drake have enjoyed six consecutive wins against Southern Illinois. They’ve landed 9 victories from the past 10 head-to-head meetings.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Southern Illinois	16-16	2336	2226	110	8-8	8-8	1L
Drake	14-20	2552	2544	8	7-12	7-8	1L

View Full Standings

Drake vs Southern Illinois Prediction & Picks

Discover our expert Drake vs Southern Illinois betting tips, featuring a match prediction, correct score suggestion and bet builder advice. Scroll down for full analysis.

Game Prediction

There’s a strong case for backing Southern Illinois on the spread in this college contest. The line looks really appealing considering you can get -115 when it comes to the favorites at -5.5.

The college hoops handicappers at Sportsgambler.com start by analyzing recent form and staying on top of injury news before making any basketball picks. From there, we interpret the story the stats are telling to help shape our predictions.

Key Drake vs Southern Illinois stats:

• The -5.5 line has been covered by Southern Illinois in 5 of their last 10 games at home.

Southern Illinois -5.5 Probability

According to the best betting apps, our pick has a 53.5% chance of delivering a return. Our analysts think there’s a stronger chance of success and calculate the probability to be closer to 60%. The wager can be recommended for this precise reason.

If you’re searching for bigger odds and feel confident that your selection will perform well, then moving the betting line can secure an increased potential payout.

Power up your bet with the latest free bets, sign-up bonuses and premium betting offers found in our in-depth guide.

Our Game Prediction

Southern Illinois -5.5 @ -115 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Jan 14, 01:56). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Drake 72 - 80 Southern Illinois

There is a speculative wager that can be enjoyed on Southern Illinois when it comes to the correct score lines. Taking them to win 80-72 should provide some entertainment.

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Drake vs Southern Illinois Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Southern Illinois are -294 favorites and that means a 75% chance of winning this college game according to the Moneyline betting odds with the sportsbooks. For those wanting to back Drake, you will find +225 about the underdogs.

The current spread is 5.5 and total points is 145.5. A Total bet is always available and can often provide value selections. If you want to wager Over 145.5, there are odds of -112.

Consider every angle when placing your college basketball wagers. The best sportsbooks have a huge selection of game lines and team props and it’s all about finding a bet which matches your prediction of the game.

Moneyline

Drake

+225

Southern Illinois

-294

Point Spread

Drake +5.5

-104

Southern Illinois -5.5

-118

Total Points

Under 145.5

-108

Over 145.5

-112

If you have a view on Total Points, Three-Pointers, Assists, Double-Doubles or Triple-Doubles, then the player prop betting could be up your street. It’s a great way of wagering on individual performance.

Micro betting provides a rollercoaster ride for college basketball bettors. It can be great to enjoy the live lines, with the opportunity to bet on the Next Field Goal. Watch the live action before deciding which way to go.

Latest regular season and playoff games stats.

Drake Stats

Southern Illinois Stats

Moneyline

• 1 win and 9 defeats in the last 10 games
• 3 wins and 7 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 4 wins and 6 defeats in the last 10 home games

Point Spread

• +4.5 Betting Line: Have covered the spread in 2 of the last 10 games
• +4.5 Betting Line on the Road: Have covered the spread in 4 of the last 10 games on the road

Point Spread

• -4.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -4.5 Betting Line at Home: Have covered the spread in 4 of the last 10 home games

Total Points

• Game Totals: An average of 153.00 pts in the previous 10 games
• Game Totals on the Road: An average of 151.90 pts in the previous 10 games on the road
• Over 137.5: Covered in 8 of the previous 10 games
• Over 137.5 on the Road: Covered in 9 of the previous 10 games on the road
• Team Totals: Have scored an average of 71.40 pts and allowed 81.60 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 72.20 pts and allowed 79.70 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 134.30 pts in the previous 10 games
• Game Totals at Home: An average of 139.60 pts in the previous 10 home games
• Over 137.5: Covered in 4 of the previous 10 games
• Over 137.5 at Home: Covered in 6 of the previous 10 home games
• Team Totals: Have scored an average of 69.90 pts and allowed 64.40 pts in the last 10 games
• Team Totals at Home: Have scored an average of 70.80 pts and allowed 68.80 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Missouri Valley	Overall	PF	PA	N. Pts	Home	Away	Strk
Belmont	26-6	2684	2347	337	15-3	11-3	2L
Northern Iowa	23-12	2447	2144	303	13-5	10-7	5W
Bradley	21-12	2560	2422	138	17-4	4-8	1L
Illinois State	20-12	2404	2190	214	15-4	5-8	1L
Murray State	20-12	2667	2558	109	14-4	6-8	2L
UIC	19-15	2567	2379	188	11-7	8-8	1L
Valparaiso	17-15	2278	2300	-22	13-4	4-11	1L
Southern Illinois	16-16	2336	2226	110	8-8	8-8	1L
Drake	14-20	2552	2544	8	7-12	7-8	1L
Indiana State	11-21	2354	2383	-29	8-7	3-14	1L
Evansville	7-25	2143	2447	-304	5-12	2-13	2L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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