Once Caldas vs Santa Fe Prediction, Betting Tips & Odds | 25 Jan 2026

Primera A Betting Preview: Once Caldas vs Santa Fe

Once Caldas clash with Santa Fe, with kick-off set for 20:20 on Sunday 25 January.

The best plan could involve backing Santa Fe with a +0.25 Asian Handicap at -123 when clashing with Once Caldas. Our stake is split between 0 and +0.5, allowing us to land a return in the event of a draw.

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Once Caldas won last time out by a 2-1 scoreline. It was away from home against Cucuta.

Santa Fe drew their previous Primera A game which was at home. The action ended 1-1 against Águilas Doradas.

Head-to-Head Statistics

Once Caldas defeated Santa Fe away when the sides last clashed. It was a 2-1 scoreline. The 10 H2H games most recently played have featured six Santa Fe wins, one draw and three victories for Once Caldas.

Categoria Primera A		G	W	D	L	GF	GA	GD	GD	P
9	Once Caldas	1	1	0	0	2	1	1	2:1	3
13	Santa Fe	1	0	1	0	1	1	0	1:1	1

View Full Table

Once Caldas vs Santa Fe Prediction & Betting Tips

This Once Caldas vs Santa Fe betting breakdown features a main match prediction, a correct score insight, expert player prop picks and a sharply constructed bet builder to guide your wagers.

Match Prediction

Santa Fe +0.25 on the Asian Handicap looks like a sensible play at a price of -123. They should be able to swerve a loss in this Primera A game and we’re confident that the away team can land a victory.

The Primera A form is always taken into consideration and it’s great to combine this with team news as it becomes available. In order to provide expert football betting tips, the latest stats are analysed so that we have the best information.

Key Once Caldas vs Santa Fe league stats:

• The +0.25 line has been covered by Santa Fe in 3 consecutive games.
• The +0.25 line has been covered by Santa Fe in 15 of their last 20 games on the road.
• The +0.25 line has been covered by Santa Fe in 7 of their last 10 games.
• The -0.25 line hasn’t been covered by Once Caldas in 12 of their last 20 games.
• The -0.25 line hasn’t been covered by Once Caldas in 7 of their last 10 games against Santa Fe.

If you go by the top bookies, there’s a 55.2% likelihood of our pick winning. However, our tipsters in-depth research has found that the actual probability is between 60-65%. This is why we regard this as a value bet.

If you’re in search of a larger price, there are lots of options for those wanting to sell goals. The wager is riskier but will provide a bigger reward should it win.

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Our Match Prediction

Santa Fe Asian Hcp +0.25 @ -123 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (02:37, 24 January 2026). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Once Caldas 1 - 2 Santa Fe

Let’s take a chance on the +750 available that Santa Fe secure a 2-1 victory. There’s a nice potential return waiting if we’re able to predict the correct score.

Player Prop Picks

Top Pick: Hugo Rodallega To Score +180

Hugo Rodallega (Santa Fe) can be backed at +180 to find the net. There are appealing odds on offer for this Anytime Goalscorer pick and we think this is an attractive wager for him to be on the scoresheet.

Latest Hugo Rodallega Player Prop Odds

Goalscorer

Anytime

+145

First

+300

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Once Caldas vs Santa Fe Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

The bookmakers have Once Caldas at +118 when it comes to 1x2. This suggests that the favourites have a 46% chance of winning this Primera A clash based on the betting odds. If you’re looking for an alternative angle, Santa Fe are trading at +230.

It sometimes pays to take the Draw No Bet option meaning there’s a safety net if the game ends all square. Once Caldas can be backed at -182 or alternatively Santa Fe are on offer at +128.

The Total Goals odds suggest that Under 2.5 is the likelier outcome in this contest. If you’re betting on Both Teams to Score, you can back Yes at -116 and No at -122.

The best football betting sites will provide a first-class service and that includes getting hundreds of markets. Scan through them for any Primera A game and take your pick.

Full-Time Result

1

+118

X

+205

2

+230

Half-Time Result

1

+180

X

+108

2

+285

Double Chance

1X

-357

12

-333

X2

-175

Draw No Bet

1

-182

2

+128

Asian Handicap

1 Hcp -0.25

-118

2 Hcp +0.25

-120

Total Goals

Under 2.5

-172

Over 2.5

+118

Both Teams to Score

Yes

-116

No

-122

Dayro Moreno can be backed to find the net anytime at -102. There is the chance to back the market leader to score the first goal at +210.

Dayro Moreno (Once Caldas)

First

-102

Anytime

+210

Hugo Rodallega (Santa Fe)

First

+145

Anytime

+300

Michael Barrios (Once Caldas)

First

+295

Anytime

+600

Nahuel Bustos (Santa Fe)

First

+360

Anytime

+700

Luis Angel Palacios (Once Caldas)

First

+510

Anytime

+950

Jorge Ramos (Santa Fe)

First

+510

Anytime

+1050

Edwin Mosquera (Santa Fe)

First

+525

Anytime

+1100

Luis Sanchez (Once Caldas)

First

+550

Anytime

+1100

Déinner Quiñones (Once Caldas)

First

+575

Anytime

+1200

Jaime Alvarado (Once Caldas)

First

+650

Anytime

+1300

Christian Mafla (Santa Fe)

First

+700

Anytime

+1300

Yilmar Andres Velasquez (Santa Fe)

First

+750

Anytime

+1500

Alexis Zapata (Santa Fe)

First

+750

Anytime

+1600

Iván Rojas (Once Caldas)

First

+850

Anytime

+1900

Kilian Toscano (Santa Fe)

First

+900

Anytime

+1800

Johan Esteban Beltran (Once Caldas)

First

+950

Anytime

+2000

Daniel Torres (Santa Fe)

First

+950

Anytime

+2000

Jhojan Torres (Santa Fe)

First

+1000

Anytime

+2000

Omar Fernandez (Santa Fe)

First

+1000

Anytime

+2000

Yeferson Rodallega (Once Caldas)

First

+1050

Anytime

+2200

Juan David Cuesta Santos (Once Caldas)

First

+1150

Anytime

+2200

Leyder Morán (Once Caldas)

First

+1200

Anytime

+2200

Once Caldas vs Santa Fe Lineups & Team News

Don’t miss the latest Once Caldas vs Santa Fe team news before you bet. We’ll provide the confirmed lineups for the Primera A plus the latest injury updates.

Once Caldas Team Page Santa Fe Team Page

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