Notre Dame vs Syracuse Prediction, Picks & Odds | 31 Jan 2026

College Basketball Betting Preview: Notre Dame vs Syracuse

The Notre Dame Fighting Irish battle the Syracuse Orange, with tip-off scheduled for 18:00 on Saturday, January 31.

The best betting angle could be Syracuse against the spread. You can land -110 that the market leaders are able to cover the -4.5 line and they are more than capable when playing Notre Dame.

Like our read on the spread? Grab the latest BetMGM promo code and read our honest review of the site before you decide where to put your money.

Notre Dame Fighting Irish lost when they last took to the court. They were turned over 100-97 (OT) at home to Virginia Cavaliers.

Syracuse Orange were defeated in their last game. On the road, they suffered a 88-68 reverse against NC State Wolfpack.

Head-to-Head Statistics

Syracuse had the edge in the most recent matchup between these teams. They recorded a 77-69 win over Notre Dame. The previous 10 H2H meetings have involved Syracuse winning seven times.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Syracuse	12-9	1581	1467	114	9-4	3-5	4L
Notre Dame	11-10	1555	1502	53	9-4	2-6	1L

View Full Standings

Notre Dame vs Syracuse Prediction & Picks

Our expert Notre Dame vs Syracuse betting tips include a main match prediction, a correct score pick and bet builder advice. Explore each section below for detailed insights.

Game Prediction

We’re excited to see Syracuse at -4.5 on the spread in this college matchup. We think it’s a great number for the betting favorites to cover at odds of -110.

Tracking injury updates is a big part of our college hoops analysis and team news plays a major role in shaping our basketball picks. We combine this with recent form and the most important stats to get a complete picture.

Key Notre Dame vs Syracuse stats:

• The -4.5 line has been covered by Syracuse in 12 of their last 20 games at home.
• The +4.5 line hasn’t been covered by Notre Dame in 12 of their last 20 games on the road.
• The +4.5 line hasn’t been covered by Notre Dame in 3 of their last 5 games.
• The +4.5 line hasn’t been covered by Notre Dame in 2 consecutive games on the road.

Syracuse -4.5 Probability

According to the latest betting odds, our pick has a 52.4% chance of winning. Taking all factors into consideration, our cappers think there’s a stronger chance of success and estimate the probability to be closer to 60%. That means we’re regarding it as a value bet.

Looking for more juice from your selection? By moving the betting line, you are able to get bigger odds although you will need to take a riskier bet.

Your next bet could start with a welcome bonus. Explore our expert guide to the newest sign-up and betting offers.

Our Game Prediction

Syracuse -4.5 @ -110 Bet Now

BetMGM Promo Up To $1500 in Bonus Bets Get Bonus T&C apply. Gamble responsibly 18+

Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (15:56, 31 January 2026). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Notre Dame 73 - 80 Syracuse

Let’s roll the dice and try Syracuse to achieve a 80-73 winning scoreline. There are huge betting odds for this potential outcome and it’s a fun type of wager to enjoy.

T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Notre Dame vs Syracuse Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Syracuse are -227 favorites and that means a 69% chance of winning this college game according to the Moneyline betting odds with the sportsbooks. For those wanting to oppose the market leader, you can get +184 about Notre Dame.

The current spread is 4.5 and total points is 147.5. There is no denying the popularity of betting on the Totals. If you’re going for Over 147.5, then the odds are -110.

If you’re betting on college basketball, we recommend heading to the top betting sites and scanning through the wide range of team props and game lines. There’s the opportunity to wager pre-game and in-game.

Moneyline

Notre Dame

+184

Syracuse

-227

Point Spread

Notre Dame +4.5

-110

Syracuse -4.5

-110

Total Points

Under 147.5

-110

Over 147.5

-110

There is regularly betting value to be found from wagering on the player props with the best online gambling sites. You can find lots of ways to back for or against a specific player lining up for one of the two teams.

You don’t have to wait for the final outcome when it comes to college basketball micro betting. Instead, there’s the opportunity to wager on live lines which tend to be settled in a shorter space of time and the in-game odds are always changing.

Latest regular season and playoff games stats.

Notre Dame Stats

Syracuse Stats

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 home games

Point Spread

• +4.5 Betting Line: Have covered the spread in 6 of the last 10 games
• +4.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• -4.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -4.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games

Total Points

• Game Totals: An average of 145.20 pts in the previous 10 games
• Game Totals on the Road: An average of 138.50 pts in the previous 10 games on the road
• Over 145.5: Covered in 4 of the previous 10 games
• Over 145.5 on the Road: Covered in 3 of the previous 10 games on the road
• Team Totals: Have scored an average of 70.90 pts and allowed 74.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 65.70 pts and allowed 72.80 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 153.40 pts in the previous 10 games
• Game Totals at Home: An average of 144.80 pts in the previous 10 home games
• Over 145.5: Covered in 8 of the previous 10 games
• Over 145.5 at Home: Covered in 4 of the previous 10 home games
• Team Totals: Have scored an average of 77.90 pts and allowed 75.50 pts in the last 10 games
• Team Totals at Home: Have scored an average of 75.10 pts and allowed 69.70 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	20-1	1784	1350	434	12-0	8-1	9W
Virginia	18-3	1765	1455	310	11-1	7-2	2W
Clemson	18-4	1682	1420	262	13-1	5-3	2W
Miami	17-4	1778	1456	322	12-2	5-2	2W
North Carolina	17-4	1742	1476	266	13-0	4-4	3W
NC State	16-6	1890	1583	307	10-4	6-2	4W
Louisville	15-6	1808	1480	328	11-2	4-4	1W
SMU	15-6	1819	1628	191	13-1	2-5	1L
California	15-6	1636	1468	168	14-2	1-4	1L
Virginia Tech	16-7	1840	1703	137	13-2	3-5	1L
Stanford	14-7	1589	1528	61	9-5	5-2	3L
Syracuse	12-9	1581	1467	114	9-4	3-5	4L
Notre Dame	11-10	1555	1502	53	9-4	2-6	1L
Wake Forest	11-11	1761	1707	54	8-5	3-6	4L
Georgia Tech	11-11	1639	1627	12	10-6	1-5	3L
Florida State	9-12	1689	1671	18	8-6	1-6	1W
Boston College	9-12	1430	1436	-6	8-7	1-5	2L
Pittsburgh	9-13	1585	1564	21	7-7	2-6	1L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

Top Basketball Pages