América de Cali vs Santa Fe Prediction, Betting Tips & Odds | 09 May 2026

Primera A Betting Preview: América de Cali vs Santa Fe

América de Cali clash with Santa Fe, with kick-off set for 21:20 on Saturday 9 May.

Santa Fe look a nice wager to topple América de Cali and we can take them at -103 with a +0.25 goal headstart on the Asian Handicap. This means dividing our stake equally between 0 and +0.5 in the hope of a payout.

América de Cali won their last league match 1-0. This was a win against Deportivo Pereira, making it three Primera A home victories on the bounce.

On Thursday, América travelled to Alianza Atlético in the Copa Sudamericana and won 2-0.

Santa Fe have won three on the spin after recently recording a 3-1 home victory over Inter Bogotá.

Three days ago, Santa Fe played out a 1-1 Copa Libertadores home draw against Corinthians.

Head-to-Head Statistics

América defeated Santa Fe in their last head-to-head clash. It was a 1-0 scoreline at home. We’ve seen four Santa Fe wins, three América victories and three draws for the past 10 matches involving these teams.

Categoria Primera A		G	W	D	L	GF	GA	GD	GD	P
4	América de Cali	19	10	3	6	25	15	10	25:15	33
7	Santa Fe	19	7	8	4	29	22	7	29:22	29

View Full Table

América de Cali vs Santa Fe Prediction & Betting Tips

Get set for América de Cali vs Santa Fe with our full betting breakdown, complete with an expert match prediction, a likely final score, top player prop picks and a value-driven bet builder.

Match Prediction

Santa Fe +0.25 on the Asian Handicap looks like a sensible play at a price of -103. They should be able to swerve a loss in this Primera A game and we’re confident that the away team can land a victory.

Knowing the players that are injured give us a helping hand when putting together football betting tips. Once we’ve also looked at the Primera A form guide, we use the available stats and make predictions.

Key América de Cali vs Santa Fe league stats:

• The +0.25 line has been covered by Santa Fe in 5 consecutive games.
• The +0.25 line has been covered by Santa Fe in 9 of their last 10 games.
• The +0.25 line has been covered by Santa Fe in 16 of their last 20 games.
• The -0.25 line hasn’t been covered by América in 7 of their last 10 games against Santa Fe.

The best football bookies are estimating that there is a 50.8% likelihood of this pick landing a return. Taking all factors into consideration, our tipsters think there’s a stronger chance of success and estimate the probability to be closer to 60%. This bet can therefore be backed with confidence.

If you want to back Santa Fe without taking them on the Asian Handicap, there’s the alternative to go for a Winning Margin wager instead. There are lots of different options here.

Don’t miss out. Check our expert guide for the most rewarding betting offers, including top free bets and bonuses.

Our Match Prediction

Santa Fe Asian Hcp +0.25 @ -103 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (May 8, 03:27). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

América 0 - 1 Santa Fe

Our correct score prediction is a 1-0 win for Santa Fe which is available at odds of +650. We think they’ll achieve victory and this is a way of getting bigger odds and more excitement.

Player Prop Picks

Top Pick: Franco Fagúndez To Score +330

Franco Fagúndez (Santa Fe) can be backed to be among the goals at +330. We’ll happily take the odds that he is able to score at least one goal when it comes to wagering on Anytime Goalscorer.

Latest Franco Fagúndez Player Prop Odds

Goalscorer

Anytime

+330

First

+750

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

América de Cali vs Santa Fe Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

América de Cali are forecasted to have a 50% chance of triumphing in this Primera A encounter according to the bookmakers. It leads to their latest betting odds being -100. Santa Fe are trading at a bigger price than their opponents and the outsiders can be backed at +250.

The Draw No Bet market simplifies things as it offers two options and money back if the game finishes level. América are -213, while Santa Fe are alternatively priced at +145.

A low-scoring contest will be anticipated by many and Under 2.5 Goals currently has the shortest odds. BTTS is always an intriguing wager to have and the Yes/No selections are regarded as being evenly-matched.

The leading betting sites provide a quality service including hundreds of markets being created for every Primera A match. It’s great for football bettors to choose from so many options.

Full-Time Result

1

-100

X

+235

2

+250

Half-Time Result

1

+160

X

+114

2

+290

Double Chance

1X

-400

12

-370

X2

-147

Draw No Bet

1

-213

2

+145

Asian Handicap

1 Hcp -0.25

-137

2 Hcp +0.25

-103

Total Goals

Under 2.5

-143

Over 2.5

-100

Both Teams to Score

Yes

-123

No

-115

Those interested in favourite Jorge Daniel Valencia to find the net first are able to get +450. If the Anytime Goalscorer angle makes more appeal, then this is +200.

Jorge Daniel Valencia (América)

First

+200

Anytime

+450

Hugo Rodallega (Santa Fe)

First

+215

Anytime

+480

Yeison Guzmán (América)

First

+225

Anytime

+500

Omar Fernandez (Santa Fe)

First

+255

Anytime

+575

Adrián Ramos (América)

First

+265

Anytime

+575

Darwin Machís (América)

First

+300

Anytime

+650

Franco Fagúndez (Santa Fe)

First

+330

Anytime

+750

Joel Romero (América)

First

+340

Anytime

+750

Yojan Garcés (América)

First

+340

Anytime

+750

Tomás Ángel (América)

First

+340

Anytime

+750

Nahuel Bustos (Santa Fe)

First

+380

Anytime

+850

Jan Lucumí (América)

First

+390

Anytime

+850

Dylan Borrero (América)

First

+410

Anytime

+900

Jáder Obrian (Santa Fe)

First

+460

Anytime

+1000

Luis Angel Palacios (Santa Fe)

First

+500

Anytime

+1050

Alexis Zapata (Santa Fe)

First

+510

Anytime

+1100

Carlos Sierra (América)

First

+510

Anytime

+1100

Edwin Mosquera (Santa Fe)

First

+550

Anytime

+1100

Maximiliano Lovera (Santa Fe)

First

+550

Anytime

+1200

Rafael Carrascal (América)

First

+575

Anytime

+1200

Josen Escobar (América)

First

+575

Anytime

+1300

Mateo Castillo (América)

First

+600

Anytime

+1200

Christian Mafla (Santa Fe)

First

+700

Anytime

+1600

Yilmar Andres Velasquez (Santa Fe)

First

+750

Anytime

+1700

David Mina (América)

First

+900

Anytime

+1800

América de Cali vs Santa Fe Lineups & Team News

Make sure to look over the América vs Santa Fe team news before betting. Get the confirmed lineups for the Primera A plus the newest injury news.

América de Cali Team Page Santa Fe Team Page

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