Atlético Nacional vs Santa Fe Prediction, Betting Tips & Odds | 29 Oct 2026

Atlético Nacional vs Santa Fe Predictions

Main Match Prediction

Santa Fe Asian Hcp +1.25 @ -137

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Santa Fe +1.25 at odds of -137 allows us to split our money between +1 and +1.5. A win or draw against Atlético Nacional will result in a payout on the Asian Handicap, with a one goal defeat still seeing a return.

Continue reading for our full Atlético Nacional vs Santa Fe betting analysis, outlining the core arguments for our main match prediction, alongside our correct score prediction, player prop picks and bet builder tips.

Atlético Nacional vs Santa Fe Preview

Atlético Nacional take on Santa Fe, with kick-off set for 21:30 on Thursday 29 October.

Atlético Nacional have recorded back-to-back Primera A wins. They recently secured a 2-1 home triumph against DIM.

Santa Fe have won back-to-back Primera A games, recently registering a 2-1 home victory against Atlético Bucaramanga.

H2H: 2-1 Win for Nacional in Last Head-to-Head Clash

Nacional are unbeaten when it comes to the past three meetings against Santa Fe. In their last clash, Nacional bagged a 2-1 away win. The previous 10 H2H meetings have involved five Nacional wins, one Santa Fe victory and four draws.

Categoria Primera A		G	W	D	L	GF	GA	GD	GD	P
1	Atlético Nacional	15	10	2	3	30	13	17	30:13	32
4	Santa Fe	15	8	4	3	23	15	8	23:15	28

View Full Table

Main Match Prediction

Santa Fe enjoying a +1.25 goal start on the Asian Handicap could be a wise move at odds of -137. We anticipate a close battle when it comes to this Primera A game, so let’s back our selection with confidence.

Key stats supporting our main match prediction (league matches):

• The +1.25 line has been covered by Santa Fe in 20 consecutive games.
• The -1.25 line hasn’t been covered by Nacional in 6 of their last 10 games.
• The -1.25 line hasn’t been covered by Nacional in 12 of their last 20 games.
• The -1.25 line hasn’t been covered by Nacional in 5 consecutive games against Santa Fe.

When it comes to making our expert football predictions, it’s important to study team news and observe the latest form. There are lots of Primera A stats that can also help to shape our picks.

According to the top betting sites, our pick has a 57.8% chance of landing a return. After careful examination, our tipsters have this probability somewhere between 60-65%. The wager can be recommended for this precise reason.

Looking for a larger price when placing your wager? The good news is that you can visit the betting sites and adjust the line until you’re satisfied with the odds.

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Santa Fe Asian Hcp +1.25 @ -137 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Oct 28, 03:57). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Nacional 1 - 1 Santa Fe

There’s plenty of juice to be found by backing the two teams to draw 1-1. We can’t pass up the odds of +550 when it comes to correct score betting and it’s a fun wager.

Player Prop Picks

Top Pick: Juan Rengifo To Score +180

Juan Rengifo (Nacional) can be wagered to score at +180. We’ll take a chance with this Anytime Goalscorer wager as the betting odds look really appealing.

Latest Juan Rengifo Player Prop Odds

Goalscorer

Anytime

+180

First

+450

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Atlético Nacional vs Santa Fe Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Atlético Nacional are available at -238 to come away with a triumph in this Primera A clash, meaning a 70% likelihood of winning according to the published betting odds. If you want to back the outsider, Santa Fe are available at +575.

There’s a Half-Time Result market should you wish to predict the outcome at the break. Santa Fe are +475 here and the draw is +145, with Nacional on offer at -112.

Over 2.5 Goals is trading at a shorter price than Under 2.5 Goals right now. For Both Teams to Score betting opportunities, the market suggests that BTTS Yes and No are both equally as likely to happen.

The best football betting sites are on hand to provide lots of choice to bettors. It’s now the case that you can select from hundreds of markets for all of the Primera A matches.

Full-Time Result

1

-238

X

+335

2

+575

Half-Time Result

1

-112

X

+145

2

+475

Double Chance

1X

-1111

12

-588

X2

+148

Draw No Bet

1

-667

2

+350

Asian Handicap

1 Hcp -1.25

-104

2 Hcp +1.25

-137

Total Goals

Under 2.5

+104

Over 2.5

-149

Both Teams to Score

Yes

-120

No

-119

Those interested in Alfredo Morelos to find the net anytime are able to get -100. There is the chance to back the favourite to score the first goal at odds of +270.

Alfredo Morelos (Nacional)

First

+270

Anytime

-100

Cristian Arango (Nacional)

First

+430

Anytime

+170

Juan Rengifo (Nacional)

First

+450

Anytime

+180

James Rodríguez (Nacional)

First

+500

Anytime

+195

Marlos Moreno (Nacional)

First

+525

Anytime

+205

Ian Poveda (Nacional)

First

+550

Anytime

+225

Andres Sarmiento (Nacional)

First

+575

Anytime

+235

Hugo Rodallega (Santa Fe)

First

+650

Anytime

+260

Edwin Cardona (Nacional)

First

+650

Anytime

+270

Nicolás Rodríguez (Nacional)

First

+750

Anytime

+310

Omar Fernandez (Santa Fe)

First

+850

Anytime

+350

Franco Fagúndez (Santa Fe)

First

+950

Anytime

+390

Kevin Parra (Nacional)

First

+1000

Anytime

+420

Nahuel Bustos (Santa Fe)

First

+1100

Anytime

+430

Elias Cabrera (Nacional)

First

+1100

Anytime

+460

Jersson Gonzalez (Santa Fe)

First

+1150

Anytime

+480

Andrés Reyes (Nacional)

First

+1300

Anytime

+510

Jáder Obrian (Santa Fe)

First

+1300

Anytime

+540

Andrés Felipe Román (Nacional)

First

+1300

Anytime

+550

Luis Angel Palacios (Santa Fe)

First

+1400

Anytime

+600

Alexis Zapata (Santa Fe)

First

+1400

Anytime

+600

Mateus Uribe (Nacional)

First

+1400

Anytime

+600

Samuel Velásquez (Nacional)

First

+1400

Anytime

+600

Yeicar Alberto Perlaza Perea (Nacional)

First

+1500

Anytime

+650

William Tesillo (Nacional)

First

+1600

Anytime

+650

Atlético Nacional vs Santa Fe Lineups & Team News

Atlético Nacional Team Page Santa Fe Team Page

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