Cruzeiro vs Santos Prediction, Betting Tips, Lineups & Odds | 22 Mar 2026

Série A Betting Preview: Cruzeiro vs Santos

Cruzeiro square off against Santos, with kick-off set for 14:00 on Sunday 22 March.

We can’t pass up the chance to back BTTS Yes at -130, with both Cruzeiro and Santos expected to find the net. The Both Teams to Score market provides a great angle for a wager.

Cruzeiro were defeated in their last game. Away from home, they suffered a 2-1 loss against Athletico Paranaense. The Foxes had 52% possession and managed two shots on target, with Keny Arroyo bagging the goal.

Santos lost when they last played, being beaten 2-1 at home to Internacional. Juan Pablo Vojvoda's team had the lion’s share of the ball boasting 60% possession and two shots on goal, with Neymar on the scoresheet.

Head-to-Head Statistics

Santos have claimed back-to-back wins over Cruzeiro. There was a 3-0 home triumph after winning 2-1 away. The teams have claimed three victories in the past 6 H2H matches.

Série A		G	W	D	L	GF	GA	GD	GD	P
11	Cruzeiro	18	6	6	6	24	28	-4	24:28	24
15	Santos	18	5	6	7	26	29	-3	26:29	21

View Full Table

Cruzeiro have 5 losses and 5 draws, averaging 1.1 goals from 3.9 shots on goal and 9.5 attempts. The Belo Horizonte outfit have averaged 52.9% possession and 5.4 corners per match, with the opposition scoring 2.2 goals from 5.3 shots on goal, 10.3 attempts and 5.0 corners.

Matheus Pereira is the top goalscorer with 3, Christian Cardoso has 2, with Keny Arroyo and two other players on 1. Kaiki and Lucas Daniel Romero have racked up the most assists with 2 each.

Santos have 4 victories, 3 defeats and 3 draws, averaging 4.4 shots on goal, 10.1 attempts and 1.9 goals. The Fish average 50.6% possession, 6.3 corners awarded and 4.5 corners against, while 1.3 goals have been conceded from 8.1 attempts and 4.2 shots on goal.

Neymar has top scored with 7, while Gabriel Barbosa and Thaciano are next best on 3. Guilherme Augusto has been the top assist maker with 4 in the last 10 games.

Confirmed Lineups

Cruzeiro confirmed lineup (4-2-3-1): Matheus Cunha (GK), William, Fabricio Bruno, Lucas Villalba, Kaiki, Matheus Henrique, Gerson, Christian Cardoso, Matheus Pereira, Keny Arroyo, Neyser Villarreal.

Santos confirmed lineup (4-3-3): Gabriel Brazao (GK), Igor Vinicius, Lucas Verissimo, Luan Peres, Gonzalo Escobar, Gabriel Menino, Christian Oliva, Gustavo Henrique, Alvaro Barreal, Rony, Moises Vieira.

Cruzeiro vs Santos Prediction & Betting Tips

We’ve broken down Cruzeiro vs Santos from every angle, offering our expert match prediction, expected final score, best corners pick, player prop recommendations and a well-constructed bet builder.

Match Prediction

The teams both look good to find the net when it comes to this Série A showdown and that leads us to a BTTS Yes wager. We can land odds of -130 for this outcome and that’s an appealing price.

The latest Série A team news and current form are always useful information when it comes to providing football betting tips. It’s also important to pay attention to the available stats so that we make the best picks.

Key Cruzeiro vs Santos league stats:

• BTTS Yes has been covered in 4 straight Cruzeiro games at home.
• BTTS Yes has been covered in 7 of the last 10 Cruzeiro games.
• BTTS Yes has been covered in 13 of the last 20 Cruzeiro games at home.
• BTTS Yes has been covered in 7 straight Santos games.
• BTTS Yes has been covered in 13 of the last 20 Santos games.

The latest betting odds imply that our pick has a 56.5% prospect of winning. Based on our in-depth research, we calculate the actual probability to be 60-65%. That means we’re regarding it as a value bet.

If you want more juice from your BTTS Yes price, the Total Goals & Both Teams to Score market provides the chance to land bigger odds by combining this pick with Over 2.5 Goals.

Give your wagers a boost. Explore our bonus guide for the latest free bets, welcome bonuses and promo codes.

Our Match Prediction

Both Teams To Score - Yes @ -130 Bet Now

BetMGM Promo Up To $1500 in Bonus Bets Get Bonus T&C apply. Gamble responsibly 18+

Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Mar 20, 20:28). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Cruzeiro 1 - 1 Santos

We think there’s a chance of a 1-1 draw and this can be backed at odds of +480. We like placing a bet on correct score due to the fun element and the big potential return.

Player Prop Picks

Top Pick: Christian Roberto Cardoso to Score +500

Christian Roberto Cardoso (Cruzeiro) has scored two goals in his past five Série A games on home soil. We think there’s value in backing him for an Anytime Goalscorer prop bet at +500 which will hopefully see him find the net.

Latest Christian Roberto Cardoso Player Prop Odds

Goalscorer

Anytime

+480

First

+1200

Shots

Over 1.5

+130

Under 1.5

-

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Corners Prediction

Santos Under 4.5 Corners -156

Santos have failed to cover the 4.5 corners line in two straight games, with Cruzeiro conceding under 4.5 corners in the past four matches. When it comes to Team Corners, we’re expecting Santos to fall short and you can get odds of -156.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

Cruzeiro

Total

10.40 5.40 5.00

Home

9.80 6.20 3.60

Away

10.30 5.50 4.80

Santos

Total

10.80 6.30 4.50

Home

10.20 5.90 4.30

Away

11.60 5.40 6.20

Latest Corner Odds

Total Corners

Over 10.5

-110

Under 10.5

-130

Cruzeiro Corners

Over 6.5

+110

Under 6.5

-149

Santos Corners

Over 3.5

-147

Under 3.5

+106

Most Corners

1

-233

X

+700

2

+220

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Cruzeiro vs Santos Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The bookmakers have Cruzeiro at -139 when it comes to 1x2. This suggests that the favourites have a 58% chance of winning this Série A clash based on the betting odds. Santos are the +390 underdogs, while the draw can also be backed as an alternative.

One Asian Handicap bet involves backing Cruzeiro -0.75 at -106. If they beat Santos by 2+ goals, you get a full payout. You also get a return on half your stake if they win by one and the other half is refunded.

A low-scoring contest will be predicted by several which is reflected in the fact that Under 2.5 Goals has the shortest odds. For those anticipating both sides finding the net, then BTTS Yes might prove attractive. Alternatively, you can wager BTTS No.

When it comes to every Série A match, you will find hundreds of markets available. Go through the various attractive options which are available at the best football betting sites.

Full-Time Result

1

-139

X

+265

2

+390

Half-Time Result

1

+128

X

+123

2

+400

Double Chance

1X

-588

12

-370

X2

+106

Draw No Bet

1

-370

2

+235

Asian Handicap

1 Hcp -0.75

-106

2 Hcp +0.75

-116

Total Goals

Under 2.5

-128

Over 2.5

-100

Both Teams to Score

Yes

-115

No

-120

Francisco Da Costa is the market leader at +525 to be the First Goalscorer. Should you think he will score the last goal, then a similar price can be found.

Francisco Da Costa (Cruzeiro)

First

+210

Anytime

+525

Neymar (Santos)

First

+290

Anytime

+700

Gabriel Barbosa "Gabigol" (Santos)

First

+300

Anytime

+750

Gabigol (Santos)

First

+300

Anytime

+750

Matheus Pereira (Cruzeiro)

First

+300

Anytime

+750

Neisser Villarreal (Cruzeiro)

First

+320

Anytime

+800

Ronielson Da Silva Barbosa "Rony" (Santos)

First

+380

Anytime

+1000

Keny Arroyo (Cruzeiro)

First

+400

Anytime

+950

Ronielson Rony (Santos)

First

+400

Anytime

+1000

Gerson Santos da Silva (Cruzeiro)

First

+400

Anytime

+1000

João Japa (Cruzeiro)

First

+430

Anytime

+1100

João Melo de Oliveira "Japa" (Cruzeiro)

First

+450

Anytime

+1150

Christian Roberto Cardoso (Cruzeiro)

First

+480

Anytime

+1200

Vitor Hugo Amorim de Assis (Cruzeiro)

First

+500

Anytime

+1200

Bruno Rafael Rodrigues (Cruzeiro)

First

+500

Anytime

+1200

Lautaro Díaz (Santos)

First

+525

Anytime

+1200

Álvaro Barreal (Santos)

First

+525

Anytime

+1300

Matheus Henrique (Cruzeiro)

First

+550

Anytime

+1400

Miguel Terceros (Santos)

First

+575

Anytime

+1500

Wanderson Sousa Campos (Cruzeiro)

First

+650

Anytime

+1500

Thaciano Mickael Silva (Santos)

First

+650

Anytime

+1600

Benjamín Rollheiser (Santos)

First

+700

Anytime

+1700

Christian Oliva (Santos)

First

+700

Anytime

+1800

Kaiki Bruno da Silva (Cruzeiro)

First

+800

Anytime

+2000

Fabrício Bruno Soares de Faria (Cruzeiro)

First

+800

Anytime

+2000

Gabriel Menino (Santos)

First

+800

Anytime

+2000

Fágner Conserva Lemos (Cruzeiro)

First

+850

Anytime

+2200

Gabriel Bontempo (Santos)

First

+850

Anytime

+2200

William de Asevedo Furtado (Cruzeiro)

First

+850

Anytime

+2200

João Marcelo Ferreira (Cruzeiro)

First

+900

Anytime

+2200

Francisco Da Costa (Cruzeiro)

Over 3.5

+133

Under 3.5

-

Gabriel Barbosa "Gabigol" (Santos)

Over 2.5

+143

Under 2.5

-

Gabigol (Santos)

Over 2.5

+143

Under 2.5

-

Neisser Villarreal (Cruzeiro)

Over 2.5

+117

Under 2.5

-

Neymar (Santos)

Over 2.5

+112

Under 2.5

-

João Melo de Oliveira "Japa" (Cruzeiro)

Over 1.5

+118

Under 1.5

-

Miguel Terceros (Santos)

Over 1.5

+165

Under 1.5

-

Álvaro Barreal (Santos)

Over 1.5

+135

Under 1.5

-

Christian Roberto Cardoso (Cruzeiro)

Over 1.5

+130

Under 1.5

-

Lautaro Díaz (Santos)

Over 1.5

+123

Under 1.5

-

João Japa (Cruzeiro)

Over 1.5

+108

Under 1.5

-

Ronielson Rony (Santos)

Over 1.5

-141

Under 1.5

-

Keny Arroyo (Cruzeiro)

Over 1.5

-164

Under 1.5

-

Ronielson Da Silva Barbosa "Rony" (Santos)

Over 1.5

-147

Under 1.5

-

Matheus Pereira (Cruzeiro)

Over 1.5

-182

Under 1.5

-

Gerson Santos da Silva (Cruzeiro)

Over 1.5

+128

Under 1.5

-

Fabrício Bruno Soares de Faria (Cruzeiro)

Over 0.5

-143

Under 0.5

-

William de Asevedo Furtado (Cruzeiro)

Over 0.5

-105

Under 0.5

-

Gabriel Bontempo (Santos)

Over 0.5

-128

Under 0.5

-

Fágner Conserva Lemos (Cruzeiro)

Over 0.5

+116

Under 0.5

-

Gabriel Menino (Santos)

Over 0.5

-185

Under 0.5

-

Thaciano Mickael Silva (Santos)

Over 0.5

-244

Under 0.5

-

Kaiki Bruno da Silva (Cruzeiro)

Over 0.5

-208

Under 0.5

-

Christian Oliva (Santos)

Over 0.5

-208

Under 0.5

-

Benjamín Rollheiser (Santos)

Over 0.5

-217

Under 0.5

-

Wanderson Sousa Campos (Cruzeiro)

Over 0.5

-263

Under 0.5

-

Matheus Henrique (Cruzeiro)

Over 0.5

-270

Under 0.5

-

Bruno Rafael Rodrigues (Cruzeiro)

Over 0.5

-313

Under 0.5

-

João Marcelo Ferreira (Cruzeiro)

Over 0.5

+117

Under 0.5

-

Cruzeiro vs Santos Lineups & Team News

Stay informed and review the Cruzeiro vs Santos team news before placing your bets. We’ll share both predicted and confirmed lineups for Série A along with the latest injury news.

Cruzeiro Team Page Santos Team Page

Where to Bet on Football Games

Top Football Pages