Hoffenheim vs Lyon Prediction, Betting Tips, Lineups & Odds | 22 Oct 2026
Hoffenheim vs Lyon Predictions
If you agree with our verdict that Hoffenheim will have the edge when clashing with Lyon, then you can back the home team at -100. We’re expecting a return with this Full-Time Result bet.
Read our complete Hoffenheim vs Lyon betting preview for the full analysis behind our main match prediction, as well as our correct score prediction, player prop picks, corners prediction and bet builder tips.
Hoffenheim vs Lyon Preview
German Bundesliga team Hoffenheim host French Ligue 1 side Lyon at PreZero Arena, with kick-off set for 15:00 on Thursday 22 October.
Hoffenheim won their last game. It was on the road in the Bundesliga where Borussia Monchengladbach were beaten 2-1 at Borussia-Park. The Baden-Wurttemberg outfit managed eight shots on target and had 52% possession, with Bambase Conte and Alexander Prass scoring one goal apiece.
Lyon claimed a home win in their previous game. A 2-1 Ligue 1 victory occurred against Nice at Parc Olympique Lyonnais. Paulo Fonseca's team recorded four shots on goal and had 48% possession, while Pavel Sulc and Tanner Tessmann were both on target.
In their previous Europa League matches, Hoffenheim were beaten 3-2 when hosting Besiktas, while there was a 3-2 Lyon win at home to Crystal Palace.
H2H: 2-2 Draw in Pair’s Last Encounter
The last head-to-head saw home team Hoffenheim draw 2-2 with Lyon at PreZero Arena.
| Europa League | G | W | D | L | GF | GA | GD | GD | P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 8 |  Lyon |
2 | 2 | 0 | 0 | 5 | 3 | 2 | 5:3 | 6 |
| 30 |  Hoffenheim |
2 | 0 | 0 | 2 | 2 | 5 | -3 | 2:5 | 0 |
3 wins and 7 losses, averaging 1.4 goals from 16.4 attempts and 4.7 shots on goal. Hoffenheim have had 58.2% possession and 7.2 corners per match. On average, they have conceded 2.3 goals from 12.3 attempts and 4.3 shots on goal, while their opponents have earned 4.2 corners.
Bambase Conte, Adam Daghim and Adam Hlozek are joint-top scorers with 2 goals on the board. Vladimir Coufal is the leading assists maker with 3, while goalie Oliver Baumann has one clean sheet.
Lyon have won 6, lost 2 and drawn 2, with an average of 1.8 goals from 5.2 shots on goal and 13.0 attempts. The Auvergne-Rhône-Alpes side have averaged 51.3% possession, 5.9 corners taken and 6.1 corners against, while conceding 1.2 goals from 4.1 shots on goal and 12.3 attempts.
Ernest Nuamah is top of the team’s scoring charts with 4, while Pavel Sulc, Corentin Tolisso, Zachary Athekame and Noah Nartey have 2. Zachary Athekame and Pavel Sulc have managed 3 assists in the last 10 games, while Dominik Greif has 2 clean sheets to his name.
Predicted & Confirmed Lineups
Hoffenheim predicted lineup (4-2-3-1): Oliver Baumann (GK), Vladimir Coufal, Ozan Kabak, Koki Machida, Bernardo, Wouter Burger, Leon Avdullahu, Andrej Kramaric, Fisnik Asllani, Adam Daghim, Adam Hlozek.
Lyon predicted lineup (4-2-3-1): Dominik Greif (GK), Zachary Athekame, Felix Bacher, Ruben Kluivert, Abner Vinicius, Noah Nartey, Tyler Morton, Ernest Nuamah, Khalis Merah, Corentin Tolisso, Keito Nakamura.
Main Match Prediction
There’s a strong chance that we’ll see Hoffenheim record a victory and they are priced at -100 to win this Europa League clash. We think that the latest odds offer bettors plenty of value.
Key stats supporting our main match prediction (domestic league and Europa League matches):
Sportsgambler.com has plenty of Europa League insights and that includes getting the team news immediately. The recent form will also help deliver our expert football predictions and we ensure that the most relevant stats are used to good effect.
The betting odds at the top bookies suggest our pick carries a 50% chance of winning. After careful examination, our team calculate this probability to be closer to 60%. It is therefore regarded as a value bet.
For those bettors who want to boost their odds for Hoffenheim to secure a victory, why not combine this pick with some of the other available options in a Bet Builder.
Stop! Before you bet, grab a top welcome bonus. Check out our guide for the latest betting offers available now.
Correct Score Prediction
2
-
1
Lyon
You can secure odds of +600 that Hoffenheim are able to land a 2-1 victory. Correct score betting can provide plenty of fun and it’s a way of landing bigger odds.
Player Prop Picks
Ernest Nuamah (OL) can be wagered at -109 to record a minimum of one shot on goal. He stands out as a value pick when it comes to Shots on Target, with the recommendation being to wager this player prop pick.
Andrej Kramaric (Hoffenheim) has managed four goals in his past ten home games. He looks like a value bet to find the net and you’re able to back this Anytime Goalscorer pick at odds of +160.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Corners Prediction
Hoffenheim have had over 4.5 corners in ten straight matches, while the last 5 Lyon games have seen them concede an average of 6.60 corners. We think that there’s a strong case for this outcome and we’ll back Hoffenheim to cover the Team Corners line which is available at odds of -159.
Hoffenheim
Lyon
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Bet Builder Tips
It’s great fun to place a same-game multi and our picks are Hoffenheim to come out on top, Over 2.5 goals accompanied by Ernest Nuamah (OL) to finish with a minimum of one shot on target.
A football bet builder is a fantastic way of cheering on different selections within the same game. It results in you being able to place a tailored bet at a larger price based on the number of predictions made.
Hoffenheim vs Lyon Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
Some will want to go ahead and back Hoffenheim at -100 to win this Europa League encounter. After all, this betting price suggests a 50% chance that the favourites end up succeeding. For those wanting to oppose the market leader, you can get +230 about Lyon.
The Asian Handicap -0.5 option is the same as a win on the 1x2 market. Hoffenheim are -108 when it comes to this selection, with their opponents Lyon +0.5 at -128 which means the draw is also included with this pick.
If you’re anticipating a high-scoring contest, Over 2.5 Goals has the shortest odds. BTTS betting is always a warm order and you can bet Yes at -217 on the Both Teams to Score market.
Bettors love the flexibility that hundreds of markets provide and that is for every Europa League game. The best football betting sites ensure that their customers always have plenty of options.
Those interested in Adam Hlozek to find the net anytime can get +155, with the favourite on offer to score the first goal at odds of +460.
Latest Europa League and domestic league stats. Full Time Result, Goals, Corners and Possession.
Hoffenheim Stats
Lyon Stats
- 3 wins and 7 defeats in the previous 10 matches
- 3 wins, 5 defeats and 2 draws in the previous 10 home matches
- 6 wins, 2 defeats and 2 draws in the previous 10 matches
- 3 wins, 3 defeats and 4 draws in the previous 10 away matches
- An average of 1.40 goals scored and 2.30 conceded in the previous 10 matches
- An average of 1.60 goals scored and 1.80 conceded in the previous 10 home matches
- An average of 3.70 goals per game in the previous 10 matches
- An average of 3.40 goals per game in the previous 10 home matches
- BTTS Yes in 7 of the previous 10 matches
- BTTS Yes in 8 of the previous 10 home matches
- Over 2.5 Goals in 8 of the previous 10 matches
- Over 2.5 Goals in 7 of the previous 10 home matches
- An average of 1.80 goals scored and 1.20 conceded in the previous 10 matches
- An average of 1.10 goals scored and 1.00 conceded in the previous 10 away matches
- An average of 3.00 goals per game in the previous 10 matches
- An average of 2.10 goals per game in the previous 10 away matches
- BTTS Yes in 6 of the previous 10 matches
- BTTS Yes in 6 of the previous 10 away matches
- Over 2.5 Goals in 7 of the previous 10 matches
- Over 2.5 Goals in 5 of the previous 10 away matches
- An average of 7.20 corners awarded and 4.20 corners conceded in the last 10 matches
- An average of 7.80 corners awarded and 3.90 corners against in the last 10 home matches
- An average of 11.40 corners awarded in the last 10 matches
- An average of 11.70 corners awarded in the last 10 home matches
- Had the most corners in 8 and least corners in 2 of the last 10 matches
- Had the most corners in 8 and least corners in 2 of the last 10 home matches
- An average of 5.90 corners awarded and 6.10 corners conceded in the last 10 matches
- An average of 4.60 corners awarded and 5.60 corners against in the last 10 away matches
- An average of 12.00 corners awarded in the last 10 matches
- An average of 10.20 corners awarded in the last 10 away matches
- Had the most corners in 3 and least corners in 6 of the last 10 matches
- Had the most corners in 3 and least corners in 6 of the last 10 away matches
- An average of 58.20% possession in the last 10 matches
- An average of 57.10% possession in the last 10 home matches
- Most possession in 9 of the last 10 matches
- Most possession in 7 of the last 10 home matches
Hoffenheim vs Lyon Lineups & Team News
Make sure to look over the Hoffenheim vs OL team news before betting. We’ll provide full coverage of predicted and confirmed Europa League lineups alongside the newest injury information.
Hoffenheim Predicted Lineup 4-2-3-1
Lyon Predicted Lineup 4-2-3-1
Hoffenheim Predicted Lineup 4-2-3-1
Lyon Predicted Lineup 4-2-3-1
Previous Hoffenheim Lineups
Previous Lyon Lineups
Injuries & Suspensions
Hoffenheim Player Stats & Squad
Manager: Christian Ilzer
Lyon Player Stats & Squad
Europa League Table| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | Juventus | 2 | 2 | 0 | 0 | 7:1 | 6 |
| 2 | Leverkusen | 2 | 2 | 0 | 0 | 6:0 | 6 |
| 3 | Benfica | 2 | 2 | 0 | 0 | 6:1 | 6 |
| 4 | Besiktas | 2 | 2 | 0 | 0 | 7:3 | 6 |
| 5 | Bournemouth | 2 | 2 | 0 | 0 | 5:1 | 6 |
| 6 | Omonia Nicosia | 2 | 2 | 0 | 0 | 4:0 | 6 |
| 7 | Ferencvaros | 2 | 2 | 0 | 0 | 5:2 | 6 |
| 8 | Lyon | 2 | 2 | 0 | 0 | 5:3 | 6 |
| 9 | Sunderland | 2 | 2 | 0 | 0 | 3:1 | 6 |
| 10 | Olympiacos | 2 | 2 | 0 | 0 | 3:1 | 6 |
| 11 | Sparta Prague | 2 | 1 | 1 | 0 | 5:2 | 4 |
| 12 | Union S-G | 2 | 1 | 1 | 0 | 4:1 | 4 |
| 13 | Rennes | 2 | 1 | 1 | 0 | 2:1 | 4 |
| 14 | Dinamo Zagreb | 2 | 1 | 1 | 0 | 1:0 | 4 |
| 15 | Crystal Palace | 2 | 1 | 0 | 1 | 6:3 | 3 |
| 16 | AC Milan | 2 | 1 | 0 | 1 | 4:2 | 3 |
| 17 | Jagiellonia | 2 | 1 | 0 | 1 | 4:3 | 3 |
| 18 | OFI Crete | 2 | 1 | 0 | 1 | 3:2 | 3 |
| 19 | Torreense | 2 | 1 | 0 | 1 | 3:3 | 3 |
| 20 | AZ Alkmaar | 2 | 1 | 0 | 1 | 2:2 | 3 |
| 21 | RB Salzburg | 2 | 1 | 0 | 1 | 1:4 | 3 |
| 22 | Real Sociedad | 2 | 0 | 1 | 1 | 2:3 | 1 |
| 22 | Lillestrom | 2 | 0 | 1 | 1 | 2:3 | 1 |
| 24 | Hapoel Be'er-Sheva | 2 | 0 | 1 | 1 | 1:2 | 1 |
| 24 | Levski Sofia | 2 | 0 | 1 | 1 | 1:2 | 1 |
| 26 | Sturm Graz | 2 | 0 | 1 | 1 | 0:3 | 1 |
| 27 | NEC Nijmegen | 2 | 0 | 1 | 1 | 1:6 | 1 |
| 28 | Anderlecht | 2 | 0 | 0 | 2 | 1:3 | 0 |
| 28 | Celta Vigo | 2 | 0 | 0 | 2 | 1:3 | 0 |
| 30 | Hoffenheim | 2 | 0 | 0 | 2 | 2:5 | 0 |
| 31 | Marseille | 2 | 0 | 0 | 2 | 1:5 | 0 |
| 31 | Viktoria Plzeň | 2 | 0 | 0 | 2 | 1:5 | 0 |
| 33 | Ararat Armenia | 2 | 0 | 0 | 2 | 2:7 | 0 |
| 33 | Celtic | 2 | 0 | 0 | 2 | 2:7 | 0 |
| 35 | NK Celje | 2 | 0 | 0 | 2 | 0:5 | 0 |
| 36 | Lech | 2 | 0 | 0 | 2 | 0:8 | 0 |
| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | Juventus | 1 | 1 | 0 | 0 | 5:0 | 3 |
| 2 | Crystal Palace | 1 | 1 | 0 | 0 | 4:0 | 3 |
| 3 | Benfica | 1 | 1 | 0 | 0 | 4:1 | 3 |
| 4 | Besiktas | 1 | 1 | 0 | 0 | 4:1 | 3 |
| 5 | Bournemouth | 1 | 1 | 0 | 0 | 3:0 | 3 |
| 6 | Jagiellonia | 1 | 1 | 0 | 0 | 3:1 | 3 |
| 7 | Leverkusen | 1 | 1 | 0 | 0 | 2:0 | 3 |
| 8 | OFI Crete | 1 | 1 | 0 | 0 | 2:0 | 3 |
| 9 | Lyon | 1 | 1 | 0 | 0 | 3:2 | 3 |
| 10 | Ferencvaros | 1 | 1 | 0 | 0 | 2:1 | 3 |
| 11 | Olympiacos | 1 | 1 | 0 | 0 | 2:1 | 3 |
| 12 | Rennes | 1 | 1 | 0 | 0 | 2:1 | 3 |
| 13 | AZ Alkmaar | 1 | 1 | 0 | 0 | 2:1 | 3 |
| 14 | Omonia Nicosia | 1 | 1 | 0 | 0 | 1:0 | 3 |
| 15 | Sunderland | 1 | 1 | 0 | 0 | 1:0 | 3 |
| 16 | Dinamo Zagreb | 1 | 1 | 0 | 0 | 1:0 | 3 |
| 17 | Sparta Prague | 1 | 0 | 1 | 0 | 1:1 | 1 |
| 18 | Union S-G | 1 | 0 | 1 | 0 | 1:1 | 1 |
| 19 | NEC Nijmegen | 1 | 0 | 1 | 0 | 1:1 | 1 |
| 20 | Hapoel Be'er-Sheva | 1 | 0 | 1 | 0 | 0:0 | 1 |
| 21 | Sturm Graz | 1 | 0 | 1 | 0 | 0:0 | 1 |
| 22 | Hoffenheim | 1 | 0 | 0 | 1 | 2:3 | 0 |
| 23 | Torreense | 1 | 0 | 0 | 1 | 1:2 | 0 |
| 24 | Lillestrom | 1 | 0 | 0 | 1 | 1:2 | 0 |
| 25 | Real Sociedad | 1 | 0 | 0 | 1 | 1:2 | 0 |
| 26 | Anderlecht | 1 | 0 | 0 | 1 | 1:2 | 0 |
| 27 | Celta Vigo | 1 | 0 | 0 | 1 | 1:2 | 0 |
| 28 | Levski Sofia | 1 | 0 | 0 | 1 | 0:1 | 0 |
| 29 | Marseille | 1 | 0 | 0 | 1 | 0:1 | 0 |
| 30 | Celtic | 1 | 0 | 0 | 1 | 1:3 | 0 |
| 31 | AC Milan | 1 | 0 | 0 | 1 | 0:2 | 0 |
| 32 | Ararat Armenia | 1 | 0 | 0 | 1 | 1:4 | 0 |
| 33 | Viktoria Plzeň | 1 | 0 | 0 | 1 | 0:3 | 0 |
| 34 | NK Celje | 1 | 0 | 0 | 1 | 0:3 | 0 |
| 35 | RB Salzburg | 1 | 0 | 0 | 1 | 0:4 | 0 |
| 36 | Lech | 1 | 0 | 0 | 1 | 0:4 | 0 |
Bundesliga Table
| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | Bayern Munich | 6 | 4 | 2 | 0 | 22:5 | 14 |
| 2 | Dortmund | 6 | 4 | 2 | 0 | 11:4 | 14 |
| 3 | Freiburg | 6 | 4 | 1 | 1 | 15:6 | 13 |
| 4 | Leverkusen | 6 | 4 | 1 | 1 | 16:9 | 13 |
| 5 | Mainz 05 | 6 | 3 | 1 | 2 | 14:10 | 10 |
| 6 | Elversberg | 6 | 3 | 1 | 2 | 12:11 | 10 |
| 7 | RB Leipzig | 6 | 3 | 0 | 3 | 16:11 | 9 |
| 8 | Werder Bremen | 6 | 2 | 3 | 1 | 12:12 | 9 |
| 9 | Hamburger SV | 6 | 3 | 0 | 3 | 6:15 | 9 |
| 10 | Augsburg | 6 | 2 | 2 | 2 | 16:12 | 8 |
| 11 | Frankfurt | 6 | 2 | 2 | 2 | 10:16 | 8 |
| 12 | FC Koln | 6 | 2 | 1 | 3 | 8:11 | 7 |
| 13 | Stuttgart | 6 | 2 | 0 | 4 | 8:10 | 6 |
| 14 | Hoffenheim | 6 | 2 | 0 | 4 | 11:14 | 6 |
| 15 | Schalke 04 | 6 | 1 | 2 | 3 | 4:7 | 5 |
| 16 | Paderborn | 6 | 1 | 2 | 3 | 5:9 | 5 |
| 17 | Union Berlin | 6 | 1 | 2 | 3 | 5:17 | 5 |
| 18 | B. M'gladbach | 6 | 0 | 0 | 6 | 8:20 | 0 |
| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | Bayern Munich | 3 | 3 | 0 | 0 | 18:2 | 9 |
| 2 | RB Leipzig | 3 | 3 | 0 | 0 | 14:0 | 9 |
| 3 | Freiburg | 3 | 3 | 0 | 0 | 11:2 | 9 |
| 4 | Leverkusen | 3 | 3 | 0 | 0 | 8:1 | 9 |
| 5 | Dortmund | 3 | 2 | 1 | 0 | 7:2 | 7 |
| 6 | Werder Bremen | 3 | 2 | 1 | 0 | 8:5 | 7 |
| 7 | FC Koln | 3 | 2 | 1 | 0 | 6:4 | 7 |
| 8 | Elversberg | 3 | 2 | 0 | 1 | 8:7 | 6 |
| 9 | Hamburger SV | 3 | 2 | 0 | 1 | 3:6 | 6 |
| 10 | Augsburg | 3 | 1 | 2 | 0 | 7:4 | 5 |
| 11 | Union Berlin | 4 | 1 | 2 | 1 | 5:6 | 5 |
| 12 | Frankfurt | 3 | 1 | 1 | 1 | 4:6 | 4 |
| 13 | Stuttgart | 2 | 1 | 0 | 1 | 4:2 | 3 |
| 14 | Hoffenheim | 3 | 1 | 0 | 2 | 6:7 | 3 |
| 15 | Paderborn | 3 | 1 | 0 | 2 | 3:4 | 3 |
| 16 | Schalke 04 | 3 | 0 | 2 | 1 | 0:1 | 2 |
| 17 | Mainz 05 | 3 | 0 | 1 | 2 | 4:7 | 1 |
| 18 | B. M'gladbach | 3 | 0 | 0 | 3 | 7:10 | 0 |
Ligue 1 Table
| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | Lyon | 7 | 4 | 2 | 1 | 13:5 | 14 |
| 2 | PSG | 7 | 4 | 2 | 1 | 14:9 | 14 |
| 3 | Paris FC | 7 | 4 | 2 | 1 | 12:7 | 14 |
| 4 | Lille | 7 | 4 | 2 | 1 | 10:5 | 14 |
| 5 | Monaco | 7 | 4 | 2 | 1 | 10:6 | 14 |
| 6 | Rennes | 7 | 4 | 1 | 2 | 15:14 | 13 |
| 7 | Lorient | 7 | 3 | 2 | 2 | 7:6 | 11 |
| 8 | Lens | 7 | 3 | 1 | 3 | 14:11 | 10 |
| 9 | Marseille | 7 | 3 | 0 | 4 | 14:10 | 9 |
| 10 | Brest | 7 | 2 | 3 | 2 | 13:10 | 9 |
| 11 | Toulouse | 7 | 2 | 3 | 2 | 12:11 | 9 |
| 12 | Auxerre | 7 | 3 | 0 | 4 | 11:17 | 9 |
| 13 | Nice | 7 | 2 | 2 | 3 | 6:9 | 8 |
| 14 | Strasbourg | 7 | 2 | 1 | 4 | 12:15 | 7 |
| 15 | Angers | 7 | 2 | 1 | 4 | 9:15 | 7 |
| 16 | Le Mans | 7 | 1 | 3 | 3 | 10:15 | 6 |
| 17 | Troyes | 7 | 1 | 1 | 5 | 5:16 | 4 |
| 18 | Le Havre | 7 | 0 | 2 | 5 | 5:11 | 2 |
| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | Lyon | 4 | 3 | 1 | 0 | 10:3 | 10 |
| 2 | Rennes | 4 | 3 | 1 | 0 | 10:5 | 10 |
| 3 | Paris FC | 4 | 3 | 1 | 0 | 9:4 | 10 |
| 4 | Lille | 4 | 2 | 2 | 0 | 6:3 | 8 |
| 5 | Nice | 4 | 2 | 2 | 0 | 5:3 | 8 |
| 6 | Monaco | 3 | 2 | 1 | 0 | 6:3 | 7 |
| 7 | Lorient | 4 | 2 | 1 | 1 | 5:4 | 7 |
| 8 | Lens | 3 | 2 | 0 | 1 | 7:4 | 6 |
| 9 | Auxerre | 3 | 2 | 0 | 1 | 4:4 | 6 |
| 10 | Le Mans | 4 | 1 | 2 | 1 | 6:8 | 5 |
| 11 | Brest | 3 | 1 | 1 | 1 | 7:4 | 4 |
| 12 | Strasbourg | 3 | 1 | 1 | 1 | 4:5 | 4 |
| 13 | Marseille | 3 | 1 | 0 | 2 | 7:5 | 3 |
| 14 | PSG | 2 | 1 | 0 | 1 | 4:3 | 3 |
| 15 | Toulouse | 3 | 1 | 0 | 2 | 3:5 | 3 |
| 16 | Angers | 4 | 1 | 0 | 3 | 5:9 | 3 |
| 17 | Le Havre | 4 | 0 | 1 | 3 | 2:6 | 1 |
| 18 | Troyes | 4 | 0 | 1 | 3 | 3:11 | 1 |
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