Manchester City vs Southampton Prediction, Betting Tips, Lineups & Odds | 25 Apr 2026

FA Cup Betting Preview: Manchester City vs Southampton

Premier League outfit Manchester City host Championship club Southampton at Wembley, with kick-off set for 12:15 on Saturday 25 April.

We’re excited to back Southampton +2 at an Asian Handicap price of -118, with Man City unlikely to achieve a big victory. Our stake will be refunded if the away team lose by exactly two goals.

Manchester City won their last game 1-0. This was a Premier League road win against Burnley at Turf Moor. The Citizens recorded nine shots on target and boasted 65% possession, with Erling Haaland netting the winner early in the first half.

Southampton drew 2-2 in their previous game. This was at home in the Championship against Bristol City at St. Mary's. The South Coast outfit had four shots on goal and enjoyed 54% possession, with Cyle Larin and Ross Stewart on the scoresheet.

When last playing in the FA Cup, City were at home to Liverpool and won 4-0, while Southampton hosted Arsenal and landed a 2-1 victory.

Head-to-Head Statistics

City haven’t lost to Southampton in their past nine games, with the last clash ending in a 0-0 Premier League draw at St. Mary's. The previous 10 H2H matches have ended up with six City wins, one Southampton victory and three draws.

Premier League		G	W	D	L	GF	GA	GD	GD	P
1	Man City	33	21	7	5	66	29	37	66:29	70

Championship		G	W	D	L	GF	GA	GD	GD	P
4	Southampton	44	21	13	10	77	53	24	77:53	76

8 wins and 2 draws, averaging 2.1 goals from 18.5 attempts and 6.4 shots on goal. City have had 64.4% possession and 8.0 corners per match. On average, the opposition have scored 0.6 goals from 9.6 attempts and 3.3 shots on goal, while earning 3.5 corners.

Erling Haaland is the top scorer with 5 goals, while Nico O'Reilly and Antoine Semenyo each have 3. Rayan Cherki has the most assists with 4, while goalkeepers Gianluigi Donnarumma and James Trafford have recorded 5 clean sheets between them.

Southampton have won 8 and drawn 2, with an average of 2.2 goals from 11.8 attempts and 5.2 shots on goal. There’s been an average of 53.7% possession, 5.9 corners awarded and 4.6 corners against them, while they’ve conceded 0.8 goals from 11.5 attempts and 4.3 shots on goal.

Cyle Larin is top of the team’s scoring charts with 5, while Ross Stewart and Shea Charles both have 3. Look no further than Tom Fellows for the top assist maker (3) in the last 10 games.

Manchester City vs Southampton Prediction & Betting Tips

The Manchester City vs Southampton betting tips feature sharp analysis across major markets, including a key match prediction, player prop bets, correct score guidance and a ready-made bet builder.

Match Prediction

Betting on Southampton +2 at -118 could be a sensible play when it comes to this FA Cup clash. We expect the away team to keep the scoreline relatively close which makes this a value pick.

The first step involves analysing the form and also getting an idea of the injury situation before making any football picks. Then it’s a case of consulting the latest FA Cup stats and seeing if they can inform our opinion.

Key Manchester City vs Southampton FA Cup & league stats:

• The +2 line has been covered by Southampton in 20 consecutive games.
• The -2 line hasn’t been covered by City in 8 of their last 10 games.
• The -2 line hasn’t been covered by City in 16 of their last 20 games.
• The -2 line hasn’t been covered by City in 2 consecutive games.
• The -2 line hasn’t been covered by City in 2 consecutive games against Southampton.

The betting apps are estimating that there is a 54.1% likelihood of this pick landing a return. Based on our experts research, we calculate the actual probability to be closer to 60%. This is why we can recommend this wager.

In the quest to secure larger odds, there’s the possibility of moving the line. There are plenty of choices when it comes to doing this, so you can choose the option that suits you.

Make your bet go further. Browse our updated guide packed with the best free bets, sign-up offers and betting bonuses.

Our Match Prediction

Southampton Asian Hcp +2 @ -118 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Apr 23, 18:28). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Man City 2 - 1 Southampton

Man City can be backed to win 2-1 when it comes to the correct score. We’ll go for the +750 that this happens and hopefully we’ll get a good run for our money.

Player Prop Picks

Top Pick: Cyle Larin to Score +450

Cyle Larin (Southampton) has racked up three goals in his past five games. The odds that he will be an Anytime Goalscorer look attractive considering the numbers and we’ll plump for him to find the net at odds of +450.

Latest Cyle Larin Player Prop Odds

Goalscorer

Anytime

+450

First

+1500

Shots

Over 1.5

+112

Under 1.5

-

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Manchester City vs Southampton Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The latest Full-Time Result odds give Manchester City a 84% chance of triumphing which means that they’re overwhelming -526 favourites to win this FA Cup clash. If you want to back the outsider, Southampton are available at +1200.

Should you want to back City to lead at the break, then there is -185 available on the Half-Time Result market. Opponents Southampton have been chalked up at +700 and the draw is +205.

The Over 2.5 option is currently favourite on the Total Goals betting market. Both Teams to Score is a two-way market and, in terms of price, there’s not much to split Yes and No.

The recommended football betting sites will provide a first-class service and that includes getting hundreds of markets. Scan through them for any FA Cup match and take your pick.

Full-Time Result

1

-526

X

+600

2

+1200

Half-Time Result

1

-185

X

+205

2

+700

Double Chance

1X

-5000

12

-1111

X2

+330

Draw No Bet

1

-2000

2

+750

Asian Handicap

1 Hcp -2

-105

2 Hcp +2

-118

Total Goals

Under 2.5

+205

Over 2.5

-278

Both Teams to Score

Yes

-122

No

-114

Erling Haaland is the market leader at +215 to be First Goalscorer but if you think he will score the last goal, then a similar price can be found.

Erling Haaland (City)

First

-189

Anytime

+215

Antoine Semenyo (City)

First

+120

Anytime

+400

Omar Marmoush (City)

First

+120

Anytime

+400

Phil Foden (City)

First

+150

Anytime

+500

Rayan Cherki (City)

First

+230

Anytime

+750

Sávio de Oliveira (City)

First

+250

Anytime

+750

Tijjani Reijnders (City)

First

+250

Anytime

+850

Nico O'Reilly (City)

First

+300

Anytime

+950

Jérémy Doku (City)

First

+330

Anytime

+1050

Leo Scienza (Southampton)

First

+380

Anytime

+1200

Cyle Larin (Southampton)

First

+450

Anytime

+1500

Ross Cameron Stewart (Southampton)

First

+475

Anytime

+1500

Finn Azaz (Southampton)

First

+500

Anytime

+1500

Cameron Archer (Southampton)

First

+525

Anytime

+1700

Nico Gonzalez (City)

First

+525

Anytime

+1700

Bernardo Silva (City)

First

+575

Anytime

+1900

Ruben Dias (City)

First

+650

Anytime

+1900

Marc Guéhi (City)

First

+650

Anytime

+2000

Rodri (City)

First

+650

Anytime

+2000

Nathan Aké (City)

First

+650

Anytime

+2000

John Stones (City)

First

+650

Anytime

+2000

Josko Gvardiol (City)

First

+650

Anytime

+2200

Rico Lewis (City)

First

+650

Anytime

+2200

Rayan Aït Nouri (City)

First

+700

Anytime

+2200

Max Alleyne (City)

First

+700

Anytime

+2200

Erling Haaland (City)

Over 5.5

+104

Under 5.5

-

Omar Marmoush (City)

Over 3.5

-112

Under 3.5

-

Antoine Semenyo (City)

Over 3.5

-110

Under 3.5

-

Phil Foden (City)

Over 2.5

-139

Under 2.5

-

Leo Scienza (Southampton)

Over 1.5

-104

Under 1.5

-

Cameron Archer (Southampton)

Over 1.5

+150

Under 1.5

-

Ross Cameron Stewart (Southampton)

Over 1.5

+130

Under 1.5

-

Cyle Larin (Southampton)

Over 1.5

+112

Under 1.5

-

Finn Azaz (Southampton)

Over 1.5

+135

Under 1.5

-

Jérémy Doku (City)

Over 1.5

-135

Under 1.5

-

Nico O'Reilly (City)

Over 1.5

-114

Under 1.5

-

Tijjani Reijnders (City)

Over 1.5

-172

Under 1.5

-

Sávio de Oliveira (City)

Over 1.5

-161

Under 1.5

-

Rayan Cherki (City)

Over 1.5

-200

Under 1.5

-

Nico Gonzalez (City)

Over 0.5

-263

Under 0.5

-

Bernardo Silva (City)

Over 0.5

-156

Under 0.5

-

Ruben Dias (City)

Over 0.5

+104

Under 0.5

-

Marc Guéhi (City)

Over 0.5

+106

Under 0.5

-

Rodri (City)

Over 0.5

-133

Under 0.5

-

Nathan Aké (City)

Over 0.5

+106

Under 0.5

-

John Stones (City)

Over 0.5

+107

Under 0.5

-

Josko Gvardiol (City)

Over 0.5

+102

Under 0.5

-

Rico Lewis (City)

Over 0.5

+112

Under 0.5

-

Rayan Aït Nouri (City)

Over 0.5

-100

Under 0.5

-

Max Alleyne (City)

Over 0.5

+120

Under 0.5

-

Latest FA Cup and domestic league stats. Full Time Result, Goals, Corners and Possession.

Manchester City Stats

Southampton Stats

Full-Time Result

• 8 wins and 2 draws in the previous 10 matches
• 7 wins and 3 draws in the previous 10 home matches

Full-Time Result

• 8 wins and 2 draws in the previous 10 matches
• 8 wins and 2 draws in the previous 10 away matches

Goals

• An average of 2.10 goals scored and 0.60 conceded in the previous 10 matches
• An average of 2.90 goals scored and 0.70 conceded in the previous 10 home matches
• An average of 2.70 goals per game in the previous 10 matches
• An average of 3.60 goals per game in the previous 10 home matches
• BTTS Yes in 5 of the previous 10 matches
• BTTS Yes in 6 of the previous 10 home matches
• Over 2.5 Goals in 6 of the previous 10 matches
• Over 2.5 Goals in 6 of the previous 10 home matches

Goals

• An average of 2.20 goals scored and 0.80 conceded in the previous 10 matches
• An average of 2.40 goals scored and 1.10 conceded in the previous 10 away matches
• An average of 3.00 goals per game in the previous 10 matches
• An average of 3.50 goals per game in the previous 10 away matches
• BTTS Yes in 7 of the previous 10 matches
• BTTS Yes in 8 of the previous 10 away matches
• Over 2.5 Goals in 7 of the previous 10 matches
• Over 2.5 Goals in 6 of the previous 10 away matches

Corners

• An average of 8.00 corners awarded and 3.50 corners conceded in the last 10 matches
• An average of 5.78 corners awarded and 3.67 corners against in the last 9 home matches
• An average of 11.50 corners awarded in the last 10 matches
• An average of 9.44 corners awarded in the last 9 home matches
• Had the most corners in 8 and least corners in 1 of the last 10 matches
• Had the most corners in 6 and least corners in 1 of the last 9 home matches

Corners

• An average of 5.90 corners awarded and 4.60 corners conceded in the last 10 matches
• An average of 5.78 corners awarded and 5.56 corners against in the last 9 away matches
• An average of 10.50 corners awarded in the last 10 matches
• An average of 11.33 corners awarded in the last 9 away matches
• Had the most corners in 6 and least corners in 3 of the last 10 matches
• Had the most corners in 5 and least corners in 4 of the last 9 away matches

Possession

• An average of 64.40% possession in the last 10 matches
• An average of 61.22% possession in the last 9 home matches
• Most possession in 9 of the last 10 matches
• Most possession in 8 of the last 9 home matches

Possession

• An average of 53.70% possession in the last 10 matches
• An average of 50.89% possession in the last 9 away matches
• Most possession in 6 of the last 10 matches
• Most possession in 4 of the last 9 away matches

Manchester City vs Southampton Lineups & Team News

Before making your bets, take a look at the City vs Southampton team news. Expect the predicted and confirmed FA Cup lineups along with timely injury updates.

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