Real Madrid vs RB Leipzig Prediction, Betting Tips, Lineups & Odds | 21 Oct 2026
Real Madrid vs RB Leipzig Predictions
Real Madrid could enjoy a convincing win against Leipzig. We’re backing them at -120 with a -2 Asian Handicap, meaning money back for a two-goal victory and a bigger return if the favourites triumph by more.
Continue reading for our complete Real Madrid vs Leipzig betting analysis, delivering an in-depth look at our main match prediction, as well as our correct score prediction, player prop picks, corners prediction and bet builder tips.
Real Madrid vs RB Leipzig Preview
Spanish La Liga club Real Madrid host German Bundesliga side RB Leipzig at Santiago Bernabéu, with kick-off set for 15:00 on Wednesday 21 October.
Real Madrid won their last game 4-1 and that was in La Liga. This was recorded at Santiago Bernabéu at home to Sevilla. Jose Mourinho's men had seven shots on target and boasted 65% possession, with Kylian Mbappe bagging two, while Arda Guler and Yan Diomande also scored a goal.
RB Leipzig were defeated in their previous game. On their travels, they suffered a 6-1 Bundesliga loss against Bayern Munich at Allianz Arena. The Red Bulls had just 38% possession and totalled four shots on goal, with Andrija Maksimovic finding the net.
In the last round of the Champions League, Real overcame Roma 4-3 away, while Leipzig triumphed 1-0 at home to PSV Eindhoven.
H2H: Teams Drew 1-1 in Last Head-to-Head Encounter
A 1-1 draw occurred in the last head-to-head when Real hosted Leipzig at the Santiago Bernabéu. We’ve seen the past 4 H2H meetings involve two wins for Real, one draw and one victory for Leipzig.
| Champions League | G | W | D | L | GF | GA | GD | GD | P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 8 |  Real Madrid |
2 | 2 | 0 | 0 | 6 | 4 | 2 | 6:4 | 6 |
| 21 |  RB Leipzig |
2 | 1 | 0 | 1 | 2 | 4 | -2 | 2:4 | 3 |
8 wins and 2 losses, averaging 2.7 goals from 7.1 shots on goal and 16.5 attempts. Real have had 50.2% possession, 502.0 passes and 6.3 corners per game. On average, their opponents have scored 1.2 goals from 5.0 shots on goal and 13.7 attempts, while being awarded 5.0 corners.
Kylian Mbappe is the top scorer with 11 goals, while Arda Guler, Yan Diomande, Antonio Ruediger and Carlos Espi each have 2. Jude Bellingham, Yan Diomande and Arda Guler have recorded the most assists with 3 apiece. Meanwhile, goalkeeper Thibaut Courtois has kept 2 clean sheets.
Leipzig have won 5 and lost 5, with an average of 16.1 attempts, 6.0 shots on goal and 2.1 goals. The Saxony team average 54.0% possession, 514.5 passes, 4.9 corners in their favour and 6.0 corners against, while 2.0 goals have been conceded from 6.5 shots on goal and 13.7 attempts.
Christopher Nkunku got 4 goals, Antonio Nusa notched 3, while Andrija Maksimovic and two other players scored 2. Antonio Nusa has been chief assist maker on 3, with Maarten Vandevoordt recording 4 clean sheets in the previous 10 games.
Predicted & Confirmed Lineups
Real Madrid predicted lineup (4-2-3-1): Thibaut Courtois (GK), Denzel Dumfries, Ibrahima Konate, Antonio Ruediger, Marc Cucurella, Federico Valverde, Aurelien Tchouameni, Yan Diomande, Jude Bellingham, Brahim Diaz, Kylian Mbappe.
RB Leipzig predicted lineup (4-2-3-1): Maarten Vandevoordt (GK), Ridle Baku, Willi Orban, Castello Lukeba, David Raum, Neil El Aynaoui, Ezechiel Banzuzi, Brajan Gruda, Christopher Nkunku, Antonio Nusa, Romulo Cruz.
Main Match Prediction
We think Real Madrid can land a big win in this Champions League match. That leads us to back the favourites -2 at odds of -120 which looks like a value proposition. They should be able to score some goals.
Key stats supporting our main match prediction (domestic league and Champions League matches):
Our football betting tips are provided off the back of having access to the very latest team news. We also think it’s vital to study the form guide and delve into the most pertinent Champions League stats before coming up with a verdict.
According to the odds, there’s a 54.6% likelihood of our pick winning. However, we have this number closer to 60% based on our in-depth research. This is why we regard this as a value wager.
Want to back Madrid to cover the line at bigger odds? Get more juice by taking the Bet Builder route where different legs can be combined to good effect.
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Correct Score Prediction
3
-
0
Leipzig
Real Madrid are available at +850 when it comes to them winning 3-0. We like a correct score play and the chance to bag a nice return if our prediction is right.
Player Prop Picks
Antonio Nusa (Leipzig) has registered a minimum of one shot on goal in seven of his past ten matches. We are in favour of betting the -132 that he is able to cover the line, with this Shots on Target wager looking like it might yield dividends.
Yan Diomande (Real Madrid) has been on the scoresheet in back-to-back home games. This statistic guides us towards Anytime Goalscorer where we’re able to back him to find the net at appealing odds of +150.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Corners Prediction
In their past eight games, Leipzig have covered the 2.5 corners line, with Real Madrid conceding 5.40 corners on average in their previous 5 home matches. We endorse betting on the -143 that Leipzig successfully cover the line, with this Team Corners wager hopefully providing a return.
Real Madrid
Leipzig
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Bet Builder Tips
Our same-game multi picks are Real Madrid with an Asian Handicap of -2, BTTS No together with Antonio Nusa (Leipzig) to finish with a minimum of one shot on target.
Placing a bet builder offers a great option for football punters who are looking to focus specifically on one match. You’re able to scan through each market and pick out the selections that make the most appeal. The odds for each pick are multiplied together.
Real Madrid vs RB Leipzig Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
Real Madrid are overwhelming -435 favourites to win this Champions League clash based on the latest betting odds. The bookmakers afford them a 81% probability of claiming the spoils. If you’re looking for an alternative angle, the underdogs RB Leipzig are trading at +950.
The Half-Time Result market means that your bet will always be settled at the interval. Real are -189, while Leipzig are alternatively priced at +575 and the draw is +245.
The lowest odds can be found for Over 2.5 Goals, which means at least three goals being netted. Punters anticipating that both teams will find the net are able to land -200 for the BTTS Yes option.
For those wanting hundreds of football markets, it’s great that the top betting sites are on hand to offer this service. When it comes to every Champions League game, go for the pick which stands out the most.
There’s the chance to back Kylian Mbappé at +195 to be the First Goalscorer. He’s the favourite and available at similar odds to find the net last instead.
Latest Champions League and domestic league stats. Full Time Result, Goals, Corners and Possession.
Real Madrid Stats
RB Leipzig Stats
- 8 wins and 2 defeats in the previous 10 matches
- 9 wins and 1 draw in the previous 10 home matches
- 5 wins and 5 defeats in the previous 10 matches
- 3 wins and 7 defeats in the previous 10 away matches
- An average of 2.70 goals scored and 1.20 conceded in the previous 10 matches
- An average of 2.80 goals scored and 0.80 conceded in the previous 10 home matches
- An average of 3.90 goals per game in the previous 10 matches
- An average of 3.60 goals per game in the previous 10 home matches
- BTTS Yes in 7 of the previous 10 matches
- BTTS Yes in 7 of the previous 10 home matches
- Over 2.5 Goals in 8 of the previous 10 matches
- Over 2.5 Goals in 7 of the previous 10 home matches
- An average of 2.10 goals scored and 2.00 conceded in the previous 10 matches
- An average of 1.20 goals scored and 2.70 conceded in the previous 10 away matches
- An average of 4.10 goals per game in the previous 10 matches
- An average of 3.90 goals per game in the previous 10 away matches
- BTTS Yes in 5 of the previous 10 matches
- BTTS Yes in 8 of the previous 10 away matches
- Over 2.5 Goals in 8 of the previous 10 matches
- Over 2.5 Goals in 8 of the previous 10 away matches
- An average of 6.30 corners awarded and 5.00 corners conceded in the last 10 matches
- An average of 6.30 corners awarded and 4.70 corners against in the last 10 home matches
- An average of 11.30 corners awarded in the last 10 matches
- An average of 11.00 corners awarded in the last 10 home matches
- Had the most corners in 6 and least corners in 4 of the last 10 matches
- Had the most corners in 6 and least corners in 4 of the last 10 home matches
- An average of 4.90 corners awarded and 6.00 corners conceded in the last 10 matches
- An average of 4.70 corners awarded and 4.60 corners against in the last 10 away matches
- An average of 10.90 corners awarded in the last 10 matches
- An average of 9.30 corners awarded in the last 10 away matches
- Had the most corners in 4 and least corners in 5 of the last 10 matches
- Had the most corners in 6 and least corners in 4 of the last 10 away matches
- An average of 50.20% possession in the last 10 matches
- An average of 57.70% possession in the last 10 home matches
- Most possession in 5 of the last 10 matches
- Most possession in 8 of the last 10 home matches
Real Madrid vs RB Leipzig Lineups & Team News
Check the Real vs Leipzig team news before you place your bets. Get the latest predicted and confirmed Champions League lineups and injury news right here.
Real Madrid Predicted Lineup 4-2-3-1
RB Leipzig Predicted Lineup 4-2-3-1
Real Madrid Predicted Lineup 4-2-3-1
RB Leipzig Predicted Lineup 4-2-3-1
Previous Real Madrid Lineups
Previous RB Leipzig Lineups
Injuries & Suspensions
Real Madrid Player Stats & Squad
Manager: Jose Mourinho
RB Leipzig Player Stats & Squad
Champions League Table| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | PSG | 2 | 2 | 0 | 0 | 10:3 | 6 |
| 2 | Barcelona | 2 | 2 | 0 | 0 | 9:2 | 6 |
| 3 | Aston Villa | 2 | 2 | 0 | 0 | 9:2 | 6 |
| 4 | Stuttgart | 2 | 2 | 0 | 0 | 6:1 | 6 |
| 5 | Liverpool | 2 | 2 | 0 | 0 | 8:4 | 6 |
| 6 | Sporting | 2 | 2 | 0 | 0 | 5:1 | 6 |
| 7 | Arsenal | 2 | 2 | 0 | 0 | 4:0 | 6 |
| 8 | Real Madrid | 2 | 2 | 0 | 0 | 6:4 | 6 |
| 9 | Real Betis | 2 | 2 | 0 | 0 | 6:4 | 6 |
| 10 | Bayern Munich | 2 | 1 | 1 | 0 | 8:3 | 4 |
| 11 | Sh. Donetsk | 2 | 1 | 1 | 0 | 4:2 | 4 |
| 12 | Como | 2 | 1 | 0 | 1 | 6:4 | 3 |
| 13 | Man United | 2 | 1 | 0 | 1 | 4:2 | 3 |
| 14 | Villarreal | 2 | 1 | 0 | 1 | 5:4 | 3 |
| 15 | Atlético Madrid | 2 | 1 | 0 | 1 | 3:2 | 3 |
| 16 | Club Brugge | 2 | 1 | 0 | 1 | 6:6 | 3 |
| 17 | Man City | 2 | 1 | 0 | 1 | 4:4 | 3 |
| 18 | Dortmund | 2 | 1 | 0 | 1 | 3:3 | 3 |
| 19 | Lens | 2 | 1 | 0 | 1 | 3:4 | 3 |
| 20 | AEK | 2 | 1 | 0 | 1 | 2:3 | 3 |
| 21 | RB Leipzig | 2 | 1 | 0 | 1 | 2:4 | 3 |
| 22 | Sabah FK | 2 | 1 | 0 | 1 | 2:4 | 3 |
| 23 | Feyenoord | 2 | 1 | 0 | 1 | 4:7 | 3 |
| 24 | Bodo/Glimt | 2 | 1 | 0 | 1 | 1:5 | 3 |
| 25 | Roma | 2 | 0 | 1 | 1 | 4:5 | 1 |
| 26 | PSV | 2 | 0 | 1 | 1 | 1:2 | 1 |
| 27 | Viking | 2 | 0 | 1 | 1 | 4:6 | 1 |
| 28 | Fenerbahce | 2 | 0 | 1 | 1 | 1:7 | 1 |
| 29 | Inter Milan | 2 | 0 | 0 | 2 | 4:6 | 0 |
| 30 | Porto | 2 | 0 | 0 | 2 | 2:5 | 0 |
| 31 | Slavia Prague | 2 | 0 | 0 | 2 | 2:5 | 0 |
| 32 | Napoli | 2 | 0 | 0 | 2 | 1:4 | 0 |
| 33 | LASK | 2 | 0 | 0 | 2 | 3:7 | 0 |
| 34 | Lille | 2 | 0 | 0 | 2 | 2:6 | 0 |
| 35 | Galatasaray | 2 | 0 | 0 | 2 | 2:7 | 0 |
| 36 | Slovan Bratislava | 2 | 0 | 0 | 2 | 1:9 | 0 |
| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | Aston Villa | 1 | 1 | 0 | 0 | 6:0 | 3 |
| 2 | PSG | 1 | 1 | 0 | 0 | 6:1 | 3 |
| 3 | Bayern Munich | 1 | 1 | 0 | 0 | 5:0 | 3 |
| 4 | Barcelona | 1 | 1 | 0 | 0 | 5:1 | 3 |
| 5 | Man United | 1 | 1 | 0 | 0 | 4:0 | 3 |
| 6 | Como | 1 | 1 | 0 | 0 | 4:1 | 3 |
| 7 | Arsenal | 1 | 1 | 0 | 0 | 3:0 | 3 |
| 8 | Stuttgart | 1 | 1 | 0 | 0 | 3:1 | 3 |
| 9 | Sporting | 1 | 1 | 0 | 0 | 3:1 | 3 |
| 10 | Sh. Donetsk | 1 | 1 | 0 | 0 | 3:1 | 3 |
| 11 | Villarreal | 1 | 1 | 0 | 0 | 3:1 | 3 |
| 12 | Atlético Madrid | 1 | 1 | 0 | 0 | 2:0 | 3 |
| 13 | Sabah FK | 1 | 1 | 0 | 0 | 2:0 | 3 |
| 14 | Real Betis | 1 | 1 | 0 | 0 | 3:2 | 3 |
| 15 | Dortmund | 1 | 1 | 0 | 0 | 3:2 | 3 |
| 16 | Feyenoord | 1 | 1 | 0 | 0 | 3:2 | 3 |
| 17 | Liverpool | 1 | 1 | 0 | 0 | 2:1 | 3 |
| 18 | Real Madrid | 1 | 1 | 0 | 0 | 2:1 | 3 |
| 19 | AEK | 1 | 1 | 0 | 0 | 1:0 | 3 |
| 20 | RB Leipzig | 1 | 1 | 0 | 0 | 1:0 | 3 |
| 21 | Bodo/Glimt | 1 | 1 | 0 | 0 | 1:0 | 3 |
| 22 | Viking | 1 | 0 | 1 | 0 | 3:3 | 1 |
| 23 | PSV | 1 | 0 | 1 | 0 | 1:1 | 1 |
| 24 | Fenerbahce | 1 | 0 | 1 | 0 | 1:1 | 1 |
| 25 | Roma | 1 | 0 | 0 | 1 | 3:4 | 0 |
| 26 | Inter Milan | 1 | 0 | 0 | 1 | 3:4 | 0 |
| 27 | Club Brugge | 1 | 0 | 0 | 1 | 2:3 | 0 |
| 28 | Slavia Prague | 1 | 0 | 0 | 1 | 2:3 | 0 |
| 29 | Lille | 1 | 0 | 0 | 1 | 2:3 | 0 |
| 30 | Napoli | 1 | 0 | 0 | 1 | 0:1 | 0 |
| 31 | Man City | 1 | 0 | 0 | 1 | 2:4 | 0 |
| 32 | Lens | 1 | 0 | 0 | 1 | 0:2 | 0 |
| 33 | Porto | 1 | 0 | 0 | 1 | 0:2 | 0 |
| 34 | LASK | 1 | 0 | 0 | 1 | 3:6 | 0 |
| 35 | Galatasaray | 1 | 0 | 0 | 1 | 1:4 | 0 |
| 36 | Slovan Bratislava | 1 | 0 | 0 | 1 | 0:3 | 0 |
La Liga Table
| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | Barcelona | 9 | 9 | 0 | 0 | 39:9 | 27 |
| 2 | Atlético Madrid | 9 | 7 | 1 | 1 | 19:8 | 22 |
| 3 | Real Madrid | 9 | 7 | 0 | 2 | 23:9 | 21 |
| 4 | Real Betis | 9 | 6 | 1 | 2 | 16:14 | 19 |
| 5 | Real Sociedad | 9 | 5 | 1 | 3 | 17:17 | 16 |
| 6 | Sevilla | 9 | 4 | 2 | 3 | 14:16 | 14 |
| 7 | Alavés | 9 | 3 | 2 | 4 | 13:10 | 11 |
| 8 | Celta Vigo | 9 | 2 | 5 | 2 | 10:7 | 11 |
| 9 | Deportivo | 9 | 2 | 5 | 2 | 13:12 | 11 |
| 10 | Osasuna | 9 | 3 | 2 | 4 | 10:18 | 11 |
| 11 | Athletic Club | 7 | 2 | 3 | 2 | 7:6 | 9 |
| 12 | Villarreal | 9 | 2 | 3 | 4 | 13:13 | 9 |
| 13 | Rayo Vallecano | 8 | 2 | 3 | 3 | 12:17 | 9 |
| 14 | Getafe | 9 | 2 | 3 | 4 | 5:11 | 9 |
| 15 | Espanyol | 9 | 2 | 2 | 5 | 11:12 | 8 |
| 16 | Racing Club | 9 | 2 | 2 | 5 | 13:25 | 8 |
| 17 | Levante | 8 | 1 | 4 | 3 | 12:16 | 7 |
| 18 | Elche | 9 | 1 | 4 | 4 | 11:17 | 7 |
| 19 | Valencia | 9 | 1 | 3 | 5 | 6:15 | 6 |
| 20 | Málaga | 9 | 0 | 4 | 5 | 6:18 | 4 |
| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | Real Madrid | 5 | 5 | 0 | 0 | 17:3 | 15 |
| 2 | Barcelona | 4 | 4 | 0 | 0 | 17:4 | 12 |
| 3 | Real Betis | 5 | 4 | 0 | 1 | 10:7 | 12 |
| 4 | Atlético Madrid | 4 | 3 | 1 | 0 | 10:3 | 10 |
| 5 | Alavés | 5 | 3 | 0 | 2 | 10:5 | 9 |
| 6 | Getafe | 5 | 2 | 3 | 0 | 5:3 | 9 |
| 7 | Racing Club | 4 | 2 | 2 | 0 | 9:7 | 8 |
| 8 | Osasuna | 5 | 2 | 2 | 1 | 4:3 | 8 |
| 9 | Celta Vigo | 5 | 2 | 1 | 2 | 9:6 | 7 |
| 10 | Rayo Vallecano | 3 | 2 | 1 | 0 | 6:4 | 7 |
| 11 | Real Sociedad | 4 | 2 | 1 | 1 | 5:6 | 7 |
| 12 | Deportivo | 5 | 1 | 3 | 1 | 6:5 | 6 |
| 13 | Sevilla | 4 | 2 | 0 | 2 | 5:7 | 6 |
| 14 | Athletic Club | 4 | 1 | 2 | 1 | 5:4 | 5 |
| 15 | Levante | 3 | 1 | 1 | 1 | 10:9 | 4 |
| 16 | Villarreal | 4 | 1 | 1 | 2 | 6:6 | 4 |
| 17 | Espanyol | 5 | 1 | 1 | 3 | 6:7 | 4 |
| 18 | Málaga | 5 | 0 | 3 | 2 | 5:10 | 3 |
| 19 | Valencia | 5 | 0 | 2 | 3 | 2:9 | 2 |
| 20 | Elche | 4 | 0 | 1 | 3 | 4:11 | 1 |
Bundesliga Table
| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | Bayern Munich | 6 | 4 | 2 | 0 | 22:5 | 14 |
| 2 | Dortmund | 6 | 4 | 2 | 0 | 11:4 | 14 |
| 3 | Freiburg | 6 | 4 | 1 | 1 | 15:6 | 13 |
| 4 | Leverkusen | 6 | 4 | 1 | 1 | 16:9 | 13 |
| 5 | Mainz 05 | 6 | 3 | 1 | 2 | 14:10 | 10 |
| 6 | Elversberg | 6 | 3 | 1 | 2 | 12:11 | 10 |
| 7 | RB Leipzig | 6 | 3 | 0 | 3 | 16:11 | 9 |
| 8 | Werder Bremen | 6 | 2 | 3 | 1 | 12:12 | 9 |
| 9 | Hamburger SV | 6 | 3 | 0 | 3 | 6:15 | 9 |
| 10 | Augsburg | 6 | 2 | 2 | 2 | 16:12 | 8 |
| 11 | Frankfurt | 6 | 2 | 2 | 2 | 10:16 | 8 |
| 12 | FC Koln | 6 | 2 | 1 | 3 | 8:11 | 7 |
| 13 | Stuttgart | 6 | 2 | 0 | 4 | 8:10 | 6 |
| 14 | Hoffenheim | 6 | 2 | 0 | 4 | 11:14 | 6 |
| 15 | Schalke 04 | 6 | 1 | 2 | 3 | 4:7 | 5 |
| 16 | Paderborn | 6 | 1 | 2 | 3 | 5:9 | 5 |
| 17 | Union Berlin | 6 | 1 | 2 | 3 | 5:17 | 5 |
| 18 | B. M'gladbach | 6 | 0 | 0 | 6 | 8:20 | 0 |
| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | Bayern Munich | 3 | 3 | 0 | 0 | 18:2 | 9 |
| 2 | RB Leipzig | 3 | 3 | 0 | 0 | 14:0 | 9 |
| 3 | Freiburg | 3 | 3 | 0 | 0 | 11:2 | 9 |
| 4 | Leverkusen | 3 | 3 | 0 | 0 | 8:1 | 9 |
| 5 | Dortmund | 3 | 2 | 1 | 0 | 7:2 | 7 |
| 6 | Werder Bremen | 3 | 2 | 1 | 0 | 8:5 | 7 |
| 7 | FC Koln | 3 | 2 | 1 | 0 | 6:4 | 7 |
| 8 | Elversberg | 3 | 2 | 0 | 1 | 8:7 | 6 |
| 9 | Hamburger SV | 3 | 2 | 0 | 1 | 3:6 | 6 |
| 10 | Augsburg | 3 | 1 | 2 | 0 | 7:4 | 5 |
| 11 | Union Berlin | 4 | 1 | 2 | 1 | 5:6 | 5 |
| 12 | Frankfurt | 3 | 1 | 1 | 1 | 4:6 | 4 |
| 13 | Stuttgart | 2 | 1 | 0 | 1 | 4:2 | 3 |
| 14 | Hoffenheim | 3 | 1 | 0 | 2 | 6:7 | 3 |
| 15 | Paderborn | 3 | 1 | 0 | 2 | 3:4 | 3 |
| 16 | Schalke 04 | 3 | 0 | 2 | 1 | 0:1 | 2 |
| 17 | Mainz 05 | 3 | 0 | 1 | 2 | 4:7 | 1 |
| 18 | B. M'gladbach | 3 | 0 | 0 | 3 | 7:10 | 0 |
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