Sassuolo vs Lazio Prediction, Betting Tips, Lineups & Odds | 27 Oct 2026

Sassuolo vs Lazio Predictions

Main Match Prediction

Lazio To Win @ +123

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Lazio are capable of delivering a nice payout when they clash with Sassuolo and the price of +123 really stands out. We think that the Full-Time Result market is the best route to a potential return.

Continue reading for our full Sassuolo vs Lazio betting analysis, outlining the core arguments for our main match prediction, alongside our correct score prediction, player prop picks, corners prediction and bet builder tips.

Sassuolo vs Lazio Preview

Sassuolo host Lazio at Stadio Mapei, with kick-off set for 13:30 on Tuesday 27 October.

Sassuolo lost on the road in their last Serie A game, making it back-to-back league defeats. Como won 2-0 at Stadio Giuseppe Sinigaglia. I Neroverdi were dominated in possession with 45%, while they couldn’t manage a single shot on target.

Lazio claimed a home win in their previous game. A 2-1 triumph against Parma at Stadio Olimpico made it four consecutive victories. The Rome team racked up five shots on goal and enjoyed 68% possession, with Kenneth Taylor and Diego Carlos (own goal) finding the net.

H2H: Lazio 2-1 Winners in Last Head-to-Head Battle

It was Lazio who came out on top when they last played Sassuolo. At Stadio Olimpico, a 2-1 home win was recorded. The previous 10 H2H games have included six wins for Lazio, three triumphs for Sassuolo and a single draw.

Serie A		G	W	D	L	GF	GA	GD	GD	P
2	Lazio	8	7	1	0	16	5	11	16:5	22
14	Sassuolo	8	2	2	4	12	16	-4	12:16	8

View Full Table

Sassuolo have 2 wins, 6 losses and 2 draws, averaging 1.4 goals from 5.2 shots on goal and 13.5 attempts. The Emilia-Romagna outfit have averaged 50.3% possession, 465.5 passes and 3.7 corners per match, with their opponents getting 2.0 goals from 6.2 shots on goal, 14.8 attempts and 5.9 corners.

Vasilije Adzic leads the way with 3 goals, with Domenico Berardi and Cas Odenthal scoring 2 each. Darryl Bakola is the leading assists maker with 2.

Lazio have 8 victories, 1 defeat and 1 draw, averaging 13.6 attempts, 4.6 shots on goal and 1.8 goals. Gennaro Gattuso's side average 50.8% possession, 475.5 passes, 5.2 corners awarded and 4.7 corners against them, while 0.8 goals have been conceded from 4.7 shots on goal and 12.3 attempts.

Davide Frattesi has top scored with 3, while Gustav Isaksen, Fisayo Dele-Bashiru and Tijjani Noslin are next on 2. Mattia Zaccagni, Nuno Tavares and Tijjani Noslin are top assists providers with 3, while Christos Mandas has recorded 4 clean sheets in the previous 10 games.

Predicted & Confirmed Lineups

Sassuolo predicted lineup (4-3-3): Stefano Turati (GK), Ignace Van Der Brempt, Duje Caleta-Car, Fali Cande, Rafael Obrador, Vasilije Adzic, Nemanja Matic, Darryl Bakola, Domenico Berardi, Kieron Bowie, Benjamin Dominguez.

Lazio predicted lineup (4-3-3): Christos Mandas (GK), Romano Floriani Mussolini, Josip Sutalo, Oliver Provstgaard, Nuno Tavares, Davide Frattesi, Reda Belahyane, Kenneth Taylor, Gustav Isaksen, Tijjani Noslin, Mattia Zaccagni.

Main Match Prediction

We are big fans of Lazio at a price of +123 to win this Serie A encounter, with this wager making plenty of appeal. A nice return could be on the cards and we think a victory is within their grasp.

Key stats supporting our main match prediction (league matches):

• Lazio have won 4 consecutive games.
• Lazio have won 8 of their last 10 games.
• Lazio have won 13 of their last 20 games.
• Sassuolo have lost 6 of their last 10 games.
• Sassuolo have lost 3 of their last 5 games.
• Sassuolo have lost their last 2 games.
• Sassuolo have lost 6 of their last 10 games against Lazio.

The Serie A experts at Sportsgambler.com always keep close tabs on team news. We also use a form guide for our football betting tips along with checking out the stats that are going to help inform our final decision.

Based on the odds from the best betting apps, our pick carries a 44.8% chance of winning. Taking all factors into consideration, our experts think there’s a stronger chance of success and estimate the probability to be closer to 50%. This is why we can recommend this bet.

If you want to boost the price for Lazio to win on the Full-Time Result market, you might contemplate the Bet Builder option and combine this selection with other possible outcomes.

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Lazio To Win @ +123 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Oct 25, 19:57). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Sassuolo 1 - 2 Lazio

We’re taking a correct score bet which involves Lazio to win 2-1. The odds of +600 make plenty of appeal and you should hopefully get some entertainment with this wager.

Player Prop Picks

Top Pick: Mattia Zaccagni Over 0.5 Shots On Target -167

Mattia Zaccagni (Lazio) has had a minimum of one shot on goal in six of his past eight Serie A games. We think that the value can be found by wagering on Shots on Target and you can get -167 that he goes over the line.

Latest Mattia Zaccagni Player Prop Odds

Goalscorer

Anytime

+230

First

+700

Shots On Target

Over 0.5

-167

Under 0.5

-

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Davide Frattesi to Score +270

Davide Frattesi (Lazio) has registered two goals in his past four Serie A games on the road. Based on the numbers, we are looking to bet the +270 for him to find the net on the Anytime Goalscorer market.

Latest Davide Frattesi Player Prop Odds

Goalscorer

Anytime

+270

First

+750

Shots On Target

Over 0.5

-128

Under 0.5

-

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Corners Prediction

Lazio Over 4.5 Corners -105

Lazio have had over 4.5 corners in three consecutive games, with Sassuolo conceding over 4.5 corners in the past six matches. The Lazio Team Corners line looks attractive and we’re going to take the -105 that it’s covered.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

Sassuolo

Total

9.60 3.70 5.90

Home

9.40 3.70 5.70

Away

10.20 4.10 6.10

Lazio

Total

9.90 5.20 4.70

Home

8.40 4.40 4.00

Away

10.30 4.50 5.80

Latest Corner Odds

Total Corners

Over 8.5

-149

Under 8.5

+102

Sassuolo Corners

Over 4.5

+105

Under 4.5

-152

Lazio Corners

Over 4.5

-111

Under 4.5

-130

Most Corners

1

+105

X

+550

2

-114

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Sassuolo vs Lazio Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

With the bookies giving them a 45% probability of winning, Lazio might be a popular acca pick. Their current betting odds are +123 when it comes to triumphing in this Serie A clash. If you’re searching for a different slant, Sassuolo are available at +200.

Lazio are available at odds of -112 on the Asian Handicap -0.25. With this bet, you need them to simply beat Sassuolo to win, although a draw would see half your stake returned.

Over 2.5 Goals is the market leader and that means three or more goals are predicted. Punters anticipating that both teams will find the net are able to land -175 for the BTTS Yes option.

For those wanting hundreds of football markets, it’s great that the best sports betting sites are on hand to offer this service. When it comes to every Serie A match, go for the pick which stands out the most.

Full-Time Result

1

+200

X

+245

2

+123

Half-Time Result

1

+240

X

+128

2

+175

Double Chance

1X

-161

12

-345

X2

-270

Draw No Bet

1

+112

2

-164

Asian Handicap

1 Hcp +0.25

-123

2 Hcp -0.25

-112

Total Goals

Under 2.5

+108

Over 2.5

-139

Both Teams to Score

Yes

-175

No

+128

Gustav Isaksen is favourite to be First Goalscorer at +550, while you can get similar odds if you want him to score the last goal.

Gustav Isaksen (Lazio)

First

+550

Anytime

+190

Andrea Pinamonti (Lazio)

First

+600

Anytime

+200

Mattia Zaccagni (Lazio)

First

+700

Anytime

+230

Domenico Berardi (Sassuolo)

First

+650

Anytime

+240

Kieron Bowie (Sassuolo)

First

+700

Anytime

+240

Tijjani Noslin (Lazio)

First

+700

Anytime

+250

Matteo Cancellieri (Lazio)

First

+750

Anytime

+250

Sebastiano Esposito (Sassuolo)

First

+700

Anytime

+260

Armand Laurienté (Sassuolo)

First

+700

Anytime

+270

Davide Frattesi (Lazio)

First

+750

Anytime

+270

Vasilije Adzic (Sassuolo)

First

+900

Anytime

+310

Adrian Przyborek (Lazio)

First

+950

Anytime

+330

Kenneth Taylor (Lazio)

First

+950

Anytime

+350

Simone Cinquegrano (Sassuolo)

First

+1000

Anytime

+380

Cristian Volpato (Sassuolo)

First

+1050

Anytime

+380

Benjamín Domínguez (Sassuolo)

First

+1000

Anytime

+390

Kristian Thorstvedt (Sassuolo)

First

+1050

Anytime

+400

Danilo Cataldi (Lazio)

First

+1150

Anytime

+440

Fisayo Dele-Bashiru (Lazio)

First

+1400

Anytime

+500

Danilho Doekhi (Lazio)

First

+1400

Anytime

+500

Darryl Bakola (Sassuolo)

First

+1400

Anytime

+525

Luca Lipani (Sassuolo)

First

+1400

Anytime

+525

Ibrahim Sulemana (Sassuolo)

First

+1500

Anytime

+600

Nicolò Rovella (Lazio)

First

+1800

Anytime

+700

Andrea Ghion (Sassuolo)

First

+1900

Anytime

+750

Gustav Isaksen (Lazio)

Over 0.5

-227

Under 0.5

-

Domenico Berardi (Sassuolo)

Over 0.5

-213

Under 0.5

-

Andrea Pinamonti (Lazio)

Over 0.5

-208

Under 0.5

-

Kieron Bowie (Sassuolo)

Over 0.5

-185

Under 0.5

-

Mattia Zaccagni (Lazio)

Over 0.5

-167

Under 0.5

-

Sebastiano Esposito (Sassuolo)

Over 0.5

-167

Under 0.5

-

Armand Laurienté (Sassuolo)

Over 0.5

-164

Under 0.5

-

Tijjani Noslin (Lazio)

Over 0.5

-154

Under 0.5

-

Matteo Cancellieri (Lazio)

Over 0.5

-154

Under 0.5

-

Davide Frattesi (Lazio)

Over 0.5

-128

Under 0.5

-

Vasilije Adzic (Sassuolo)

Over 0.5

-122

Under 0.5

-

Cristian Volpato (Sassuolo)

Over 0.5

-100

Under 0.5

-

Adrian Przyborek (Lazio)

Over 0.5

+102

Under 0.5

-

Simone Cinquegrano (Sassuolo)

Over 0.5

+105

Under 0.5

-

Kenneth Taylor (Lazio)

Over 0.5

+110

Under 0.5

-

Benjamín Domínguez (Sassuolo)

Over 0.5

+110

Under 0.5

-

Kristian Thorstvedt (Sassuolo)

Over 0.5

+110

Under 0.5

-

Danilo Cataldi (Lazio)

Over 0.5

+135

Under 0.5

-

Darryl Bakola (Sassuolo)

Over 0.5

+155

Under 0.5

-

Fisayo Dele-Bashiru (Lazio)

Over 0.5

+160

Under 0.5

-

Danilho Doekhi (Lazio)

Over 0.5

+170

Under 0.5

-

Stats: Last 10 Serie A matches only.
Sassuolo have not tasted defeat at Stadio Mapei in three straight matches. I Neroverdi have collected seven victories, two losses and one draw in the last 10 home games, recording an average of 1.90 goals per match and conceding 1.10.

Lazio have secured four straight victories on their travels. The Rome team have seven wins and three defeats in the last 10 away games, scoring an average of 1.40 goals per match and conceding 0.70.

Sassuolo overcame Lazio 1-0 when the sides last met at Stadio Mapei. Both teams have secured three victories in the past 6 H2H matches at Stadio Mapei.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
Sassuolo Home Stats		7-1-2	3.00	1.90	1.10	7	3	7	3
Lazio Away Stats		7-0-3	2.10	1.40	0.70	3	7	2	8

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

Sassuolo vs Lazio Lineups & Team News

Sassuolo Team Page Lazio Team Page

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