Universidad Católica vs Cruzeiro Prediction, Betting Tips, Lineups & Odds | 06 May 2026

Copa Libertadores Betting Preview: Universidad Católica vs Cruzeiro

Chilean Primera División outfit Universidad Católica host Brazilian Série A club Cruzeiro, with kick-off set for 22:00 on Wednesday 6 May.

Universidad Católica +0.25 look like a value bet on the Asian Handicap. This involves splitting our stake between 0 and +0.5, with a win against Cruzeiro the desired outcome at betting odds of -133.

Universidad Católica won their last game 2-1. This was a Copa Libertadores away victory against Barcelona SC.

Cruzeiro were defeated in their previous game, being beaten at home to Atlético Mineiro in Série A by a 3-1 scoreline. The Foxes boasted 69% possession and had two shots on goal, while Kaio Jorge was on the scoresheet.

In the last Copa Libertadores round, Cruzeiro won 1-0 at home to Boca Juniors.

Head-to-Head Statistics

The scoreline was 2-1 in favour of away team U. Católica when they last faced Cruzeiro.

Copa Libertadores		G	W	D	L	GF	GA	GD	GD	P
1	U. Católica	4	2	1	1	5	4	1	5:4	7
2	Cruzeiro	4	2	1	1	3	2	1	3:2	7

View Full Table

Confirmed Lineups

Universidad Católica confirmed lineup (4-1-4-1): Vicente Bernedo (GK), Sebastian Arancibia, Branco Ampuero, Juan Diaz, Eugenio Mena, Jhojan Valencia, Clemente Montes, Fernando Zuqui, Cristian Cuevas, Justo Giani, Fernando Zampedri.

Cruzeiro confirmed lineup (4-2-3-1): Otavio Costa (GK), Fagner, Fabricio Bruno, Jonathan Jesus, Kaiki, Gerson, Lucas Daniel Romero, Keny Arroyo, Matheus Pereira, Christian Cardoso, Kaio Jorge.

Universidad Católica vs Cruzeiro Prediction & Betting Tips

This Universidad Católica vs Cruzeiro betting breakdown features a main match prediction, a correct score insight, expert player prop picks and a sharply constructed bet builder to guide your wagers.

Match Prediction

Universidad Católica +0.25 on the Asian Handicap could be the way forward at odds of -133. The home team should be able to avoid defeat in this Copa Libertadores clash and we’re optimistic that they can land a win.

Our football experts study the form, while injuries and suspensions can also affect the potential outcome. Before coming up with a verdict, we combine this data with the latest Copa Libertadores stats.

Key Universidad Católica vs Cruzeiro Copa Libertadores & league stats:

• The +0.25 line has been covered by U. Católica in 14 of their last 19 games at home.
• The +0.25 line has been covered by U. Católica in 7 of their last 10 games at home.
• The -0.25 line hasn’t been covered by Cruzeiro in 8 of their last 10 games on the road.
• The -0.25 line hasn’t been covered by Cruzeiro in 14 of their last 20 games.

When you look at the latest odds, our pick has a 57.1% chance of winning. However, we think that the probability sits between 60-65% taking all factors into consideration. This is why we regard this as a value wager.

If you’re looking to move the line, then you have a dual option of either buying or selling goals. It’s a case of assuming a position based on your view and attitude to risk.

Check our complete list of betting promo codes, free bet deals and the latest welcome bonuses before wagering.

Our Match Prediction

U. Católica Asian Hcp +0.25 @ -133 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (May 5, 04:27). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

U. Católica 1 - 0 Cruzeiro

U. Católica are available at +650 when it comes to them winning 1-0. We like a correct score play and the chance to bag a nice return if our prediction is right.

Player Prop Picks

Top Pick: Fernando Zampedri to Score +200

Fernando Zampedri (U. Católica) has racked up five goals in his past five home games. This data directs us to the Anytime Goalscorer market where we can bet him to find the net at attractive odds of +200.

Latest Fernando Zampedri Player Prop Odds

Goalscorer

Anytime

+200

First

+480

Shots

Over 2.5

-104

Under 2.5

-

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Universidad Católica vs Cruzeiro Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

You can get betting odds of +140 for Cruzeiro winning this Copa Libertadores clash and the bookies have Universidad Católica available at +205. If you want to back the draw, it’s on offer at +215.

There’s sometimes a case for betting on the Draw No Bet market, with Cruzeiro available at -152 for those who want insurance on their bet. The same applies to opponents U. Católica at +107.

If you’re anticipating that two goals or less will be netted throughout the contest, then Under 2.5 Goals is a definite runner. BTTS betting is always a warm order and you can bet Yes at -139 on the Both Teams to Score market.

The best football betting sites have excellent coverage for the latest Copa Libertadores games. They supply customers with hundreds of markets and it’s down to you to find the best angle.

Full-Time Result

1

+205

X

+215

2

+140

Half-Time Result

1

+245

X

+110

2

+200

Double Chance

1X

-189

12

-313

X2

-286

Draw No Bet

1

+107

2

-152

Asian Handicap

1 Hcp +0.25

-128

2 Hcp -0.25

+104

Total Goals

Under 2.5

-133

Over 2.5

+102

Both Teams to Score

Yes

-139

No

-103

Kaio Jorge can be backed to find the net anytime at +160, with +400 available that the market leader scores the first goal.

Kaio Jorge (Cruzeiro)

First

+160

Anytime

+400

Fernando Zampedri (U. Católica)

First

+200

Anytime

+480

Diego Valencia (U. Católica)

First

+250

Anytime

+600

Justo Giani (U. Católica)

First

+260

Anytime

+650

Francisco Da Costa (Cruzeiro)

First

+290

Anytime

+700

Christian Roberto Cardoso (Cruzeiro)

First

+300

Anytime

+700

Cristian Cuevas (U. Católica)

First

+320

Anytime

+800

Diego Corral (U. Católica)

First

+320

Anytime

+800

Matheus Pereira (Cruzeiro)

First

+320

Anytime

+850

Clemente Montes (U. Católica)

First

+330

Anytime

+800

Vicente Carcamo (U. Católica)

First

+400

Anytime

+950

Matías Palavecino (U. Católica)

First

+430

Anytime

+1050

Keny Arroyo (Cruzeiro)

First

+475

Anytime

+1200

Gerson Santos da Silva (Cruzeiro)

First

+525

Anytime

+1300

Jimmy Martinez (U. Católica)

First

+650

Anytime

+1700

Fernando Zuqui (U. Católica)

First

+700

Anytime

+1700

Kaiki Bruno da Silva (Cruzeiro)

First

+800

Anytime

+1900

Agustin Farias (U. Católica)

First

+800

Anytime

+2000

Alfred Canales (U. Católica)

First

+800

Anytime

+2000

Jhojan Valencia (U. Católica)

First

+850

Anytime

+2200

Bernardo Cerezo (U. Católica)

First

+900

Anytime

+2200

Kaio Jorge (Cruzeiro)

Over 3.5

-104

Under 3.5

-

Diego Valencia (U. Católica)

Over 2.5

+120

Under 2.5

-

Justo Giani (U. Católica)

Over 2.5

-112

Under 2.5

-

Fernando Zampedri (U. Católica)

Over 2.5

-104

Under 2.5

-

Clemente Montes (U. Católica)

Over 1.5

-135

Under 1.5

-

Keny Arroyo (Cruzeiro)

Over 1.5

-139

Under 1.5

-

Matías Palavecino (U. Católica)

Over 1.5

+110

Under 1.5

-

Vicente Carcamo (U. Católica)

Over 1.5

+112

Under 1.5

-

Matheus Pereira (Cruzeiro)

Over 1.5

-135

Under 1.5

-

Diego Corral (U. Católica)

Over 1.5

-143

Under 1.5

-

Cristian Cuevas (U. Católica)

Over 1.5

-137

Under 1.5

-

Christian Roberto Cardoso (Cruzeiro)

Over 1.5

-114

Under 1.5

-

Francisco Da Costa (Cruzeiro)

Over 1.5

-167

Under 1.5

-

Gerson Santos da Silva (Cruzeiro)

Over 0.5

-192

Under 0.5

-

Jimmy Martinez (U. Católica)

Over 0.5

-159

Under 0.5

-

Fernando Zuqui (U. Católica)

Over 0.5

-154

Under 0.5

-

Kaiki Bruno da Silva (Cruzeiro)

Over 0.5

-111

Under 0.5

-

Agustin Farias (U. Católica)

Over 0.5

-103

Under 0.5

-

Alfred Canales (U. Católica)

Over 0.5

-104

Under 0.5

-

Jhojan Valencia (U. Católica)

Over 0.5

-102

Under 0.5

-

Bernardo Cerezo (U. Católica)

Over 0.5

+112

Under 0.5

-

Latest Copa Libertadores and domestic league stats. Full Time Result, Goals, Corners and Possession.

Universidad Católica Stats

Cruzeiro Stats

Full-Time Result

• 5 wins, 4 defeats and 1 draw in the previous 10 matches
• 6 wins, 3 defeats and 1 draw in the previous 10 home matches

Full-Time Result

• 6 wins, 3 defeats and 1 draw in the previous 10 matches
• 2 wins, 5 defeats and 3 draws in the previous 10 away matches

Goals

• An average of 2.00 goals scored and 1.50 conceded in the previous 10 matches
• An average of 2.00 goals scored and 1.20 conceded in the previous 10 home matches
• An average of 3.50 goals per game in the previous 10 matches
• An average of 3.20 goals per game in the previous 10 home matches
• BTTS Yes in 8 of the previous 10 matches
• BTTS Yes in 7 of the previous 10 home matches
• Over 2.5 Goals in 8 of the previous 10 matches
• Over 2.5 Goals in 7 of the previous 10 home matches

Goals

• An average of 1.30 goals scored and 1.00 conceded in the previous 10 matches
• An average of 1.00 goals scored and 2.10 conceded in the previous 10 away matches
• An average of 2.30 goals per game in the previous 10 matches
• An average of 3.10 goals per game in the previous 10 away matches
• BTTS Yes in 4 of the previous 10 matches
• BTTS Yes in 5 of the previous 10 away matches
• Over 2.5 Goals in 5 of the previous 10 matches
• Over 2.5 Goals in 6 of the previous 10 away matches

Corners

• An average of 4.43 corners awarded and 4.29 corners conceded in the last 7 matches
• An average of 5.00 corners awarded and 4.78 corners against in the last 9 home matches
• An average of 8.71 corners awarded in the last 7 matches
• An average of 9.78 corners awarded in the last 9 home matches
• Had the most corners in 4 and least corners in 3 of the last 7 matches
• Had the most corners in 5 and least corners in 4 of the last 9 home matches

Corners

• An average of 3.86 corners awarded and 3.57 corners conceded in the last 7 matches
• An average of 5.00 corners awarded and 5.22 corners against in the last 9 away matches
• An average of 7.43 corners awarded in the last 7 matches
• An average of 10.22 corners awarded in the last 9 away matches
• Had the most corners in 3 and least corners in 4 of the last 7 matches
• Had the most corners in 5 and least corners in 4 of the last 9 away matches

Possession

• An average of 57.43% possession in the last 7 matches
• An average of 53.89% possession in the last 9 home matches
• Most possession in 7 of the last 7 matches
• Most possession in 6 of the last 9 home matches

Possession

• An average of 59.43% possession in the last 7 matches
• An average of 55.33% possession in the last 9 away matches
• Most possession in 7 of the last 7 matches
• Most possession in 7 of the last 9 away matches

Universidad Católica vs Cruzeiro Lineups & Team News

Don’t bet on U. Católica vs Cruzeiro without reviewing the latest team news. Get the latest predicted and confirmed Copa Libertadores lineups and injury news right here.

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