Buffalo vs Penn State Prediction, Picks & Odds | 19 Sep 2026
College Football Betting Preview: Buffalo vs Penn State
Buffalo face Penn State at Beaver Stadium, with kickoff scheduled for 12:00 on Saturday, September 19.
Buffalo might be the underdogs but +40.5 looks way too big on the spread. We’re keen to snap up the -105 that the line is covered against Penn State.
Buffalo Bulls were defeated in their previous game. On the road, they suffered a 33-20 reverse against Florida International Panthers at Pitbull Stadium.
Penn State Nittany Lions won their last game 27-9, making it back-to-back successes. This was a road victory at Lincoln Financial Field against Temple Owls.
Head-to-Head Statistics
Penn State beat Buffalo when the teams last met. It was a 45-13 scoreline at Beaver Stadium.
Buffalo vs Penn State Prediction & Picks
Our Buffalo vs Penn State tips include the main match prediction, a correct score forecast, bet builder advice and top player prop picks. Each section below offers expert insight into the key betting angles.
Game Prediction
The best wager could be Buffalo at -105 on the spread. They’ve been given a +40.5 points start and should be able to stay relatively close to the favorites in this college football showdown.
To deliver the best possible college football picks, we start by locking in the team news and taking time to review the latest form. There’s also no shortage of data to crunch from the most up-to-date stats available.
Key Buffalo vs Penn State stats:
Buffalo +40.5 Probability
According to the best betting apps, our pick has a 51.3% chance of winning. Our cappers think there’s a stronger chance of success and calculate the probability to be closer to 60%. This is why we regard this as a value wager.
There’s often the alternative to sell points and that allows you to leverage a bigger potential payout. Conversely, buying points will give you a less-risky bet but smaller odds.
Ready to wager? First, explore top-tier betting promo codes, free bets, and welcome bonuses with our expert bonus guide.
Player Prop Picks
The odds for Rocco Becht (Penn State) to end with fewer than 259.5 passing yards stand at -114. There’s no reason to doubt our instinct, so we’ll bet on him falling short of the QB Passing Yards line.
You can place a bet on Carson Hansen (Penn State) at -114 to record fewer than 88.5 rushing yards. He is likely to fall short of the line, making this Player Rushing Yards bet an appealing option.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Picks
Get in the game with a same game parlay. Our picks are Buffalo to cover the +40.5 spread, Under 49.5 on the total and Rocco Becht (Penn State) to go Under 259.5 passing yards.
We recommend a same game parlay as it’s a great way of betting on a single event. Many football bettors like to create a personalised wager which reflects their predictions for how a game is going to play out.
Correct Score Prediction
6
-
38
Penn State
There’s lots of entertainment when it comes to a correct score wager. A play on the Lions to achieve a 38-6 win should give bettors a good run for their money.
Buffalo vs Penn State Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
Due to Penn State being overwhelming favorites, you are unlikely to find any juice on the Moneyline. However, there’s an alternative angle by looking at the spread for this college game.
The current spread is 40.5 and the total points line is 49.5. A Total bet relates to the number of points that will be scored overall. If you’re going for Under 49.5, this outcome can be backed at -115.
The good news is that you can access a wide range of team props and game lines for most college football clashes. The top betting sites offer a great selection of pre-game and in-game wagering options.
Receiving Yards
Rushing Yards
Penn State Hold Seven Wins From Last Ten at Home
Penn State have a 7-3 record in their last 10 home games, putting up 36.50 points on average and giving up 12.30.
Buffalo are 6-4 in their last 10 road games, averaging 25.60 points scored and 25.00 points allowed.
The last Beaver Stadium meeting saw Penn State beat Buffalo 45-13.
| Last 10 Games | W-L | P | PF | PA | O49.5 | U49.5 | |
|---|---|---|---|---|---|---|---|
 Penn State Home Stats |
7-3 | 48.80 | 36.50 | 12.30 | 5 | 5 | |
 Buffalo Away Stats |
6-4 | 50.60 | 25.60 | 25.00 | 6 | 4 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O49.5 = Games Over 49.5 Points
- U49.5 = Games Under 49.5 Points
Latest regular season and playoff games stats.
Buffalo Bulls Stats
Penn State Nittany Lions Stats
- 4 wins and 6 defeats in the last 10 games
- 6 wins and 4 defeats in the last 10 games on the road
- +40.5 Betting Line: Have covered the spread in the last 10 games
- +40.5 Betting Line on the Road: Have covered the spread in the last 10 games on the road
- -40.5 Betting Line: Have covered the spread in 1 of the last 10 games
- -40.5 Betting Line at Home: Have covered the spread in 2 of the last 10 home games
- Game Totals: An average of 48.00 pts in the previous 10 games
- Game Totals on the Road: An average of 50.60 pts in the previous 10 games on the road
- Over 49.5: Covered in 5 of the previous 10 games
- Over 49.5 on the Road: Covered in 6 of the previous 10 games on the road
- Team Totals: Have scored an average of 22.60 pts and allowed 25.40 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 25.60 pts and allowed 25.00 pts in the last 10 games on the road
- Game Totals: An average of 46.90 pts in the previous 10 games
- Game Totals at Home: An average of 48.80 pts in the previous 10 home games
- Over 49.5: Covered in 3 of the previous 10 games
- Over 49.5 at Home: Covered in 5 of the previous 10 home games
- Team Totals: Have scored an average of 28.20 pts and allowed 18.70 pts in the last 10 games
- Team Totals at Home: Have scored an average of 34.50 pts and allowed 14.30 pts in the last 10 home games
| Big Ten | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Indiana
|
2 | 0 | 107 | 16 | 91 | 2-0 | 0-0 | 2W |
Washington
|
2 | 0 | 40 | 24 | 16 | 2-0 | 0-0 | 2W |
Wisconsin
|
1 | 1 | 49 | 50 | -1 | 1-0 | 0-1 | 1W |
Purdue
|
1 | 1 | 80 | 57 | 23 | 1-1 | 0-0 | 1L |
Oregon
|
1 | 1 | 65 | 66 | -1 | 1-0 | 0-1 | 1L |
Ohio State
|
1 | 1 | 79 | 27 | 52 | 1-0 | 0-1 | 1L |
Minnesota
|
1 | 1 | 72 | 45 | 27 | 1-1 | 0-0 | 1L |
Illinois
|
1 | 1 | 69 | 54 | 15 | 1-1 | 0-0 | 1L |
USC
|
3 | 0 | 130 | 56 | 74 | 3-0 | 0-0 | 3W |
Iowa
|
2 | 0 | 56 | 13 | 43 | 2-0 | 0-0 | 2W |
UCLA
|
2 | 0 | 73 | 34 | 39 | 1-0 | 1-0 | 2W |
|
Penn State
|
2 | 0 | 72 | 9 | 63 | 1-0 | 1-0 | 2W |
Northwestern
|
1 | 0 | 34 | 18 | 16 | 1-0 | 0-0 | 1W |
Nebraska
|
2 | 0 | 105 | 28 | 77 | 2-0 | 0-0 | 2W |
Michigan
|
2 | 0 | 30 | 22 | 8 | 2-0 | 0-0 | 2W |
Michigan State
|
2 | 0 | 65 | 27 | 38 | 2-0 | 0-0 | 2W |
Maryland
|
2 | 0 | 100 | 14 | 86 | 1-0 | 1-0 | 2W |
Rutgers
|
0 | 2 | 42 | 65 | -23 | 0-1 | 0-1 | 2L |
| Mid-American | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Eastern Michigan
|
1 | 2 | 56 | 79 | -23 | 1-1 | 0-1 | 2L |
UMass
|
2 | 0 | 74 | 31 | 43 | 1-0 | 1-0 | 2W |
Akron
|
1 | 1 | 61 | 48 | 13 | 1-0 | 0-1 | 1W |
Ball State
|
1 | 1 | 44 | 73 | -29 | 1-0 | 0-1 | 1W |
|
Buffalo
|
1 | 1 | 41 | 50 | -9 | 1-0 | 0-1 | 1L |
Central Michigan
|
1 | 1 | 20 | 48 | -28 | 1-0 | 0-1 | 1W |
Kent State
|
1 | 1 | 36 | 72 | -36 | 1-0 | 0-1 | 1W |
Miami (OH)
|
1 | 1 | 59 | 66 | -7 | 1-0 | 0-1 | 1W |
Ohio
|
1 | 1 | 50 | 76 | -26 | 1-0 | 0-1 | 1W |
Toledo
|
1 | 1 | 83 | 40 | 43 | 1-0 | 0-1 | 1W |
Western Michigan
|
1 | 1 | 61 | 27 | 34 | 1-0 | 0-1 | 1W |
Bowling Green
|
0 | 2 | 20 | 76 | -56 | 0-1 | 0-1 | 2L |
Sacramento State
|
1 | 2 | 72 | 77 | -5 | 1-0 | 0-2 | 1L |
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