Iowa vs Michigan Prediction, Picks & Odds | 26 Sep 2026

College Football Betting Preview: Iowa vs Michigan

Iowa go up against Michigan at Michigan Stadium, with kickoff scheduled for 15:30 on Saturday, September 26.

We’re expecting Over 38.5 points to be scored by Michigan and Iowa combined. There’s an attractive -110 for our prediction and we’re anticipating that the scoreboard will tick over.

Iowa Hawkeyes beat Northern Iowa Panthers in their previous game, making it three straight victories. It was a 55-0 home win at Kinnick Stadium.

Michigan Wolverines won their last game 52-17, making it three victories on the bounce. This was a home win at Michigan Stadium against UTEP Miners.

Head-to-Head Statistics

Michigan beat Iowa when the teams last met. It was a 26-0 scoreline at Kinnick Stadium. Michigan have a 100% win record when it comes to the previous 4 H2H meetings.

Quarterbacks

Hank Brown

155.5 Passing Yards

Over -114

Under -114

Bryce Underwood

174.5 Passing Yards

Over -114

Under -114

Iowa vs Michigan Prediction & Picks

Get fully prepped for Iowa vs Michigan with our betting guide, featuring our expert match pick, predicted scoreline, top player props and a value-focused bet builder.

Game Prediction

We think that 38.5 is a more than generous total for Over backers in this college football showdown. Take the -110 that we see the teams combine to good effect.

The CFB handicappers at Sportsgambler.com regularly track injury updates and pair that with current form. We also tap into a deep stats database to highlight the key numbers that help shape our picks.

Key Iowa vs Michigan stats:

• The 38.5 line has been covered in 4 of the last 5 Iowa games.
• The 38.5 line has been covered in 7 of the last 10 Iowa games.
• The 38.5 line has been covered in the last 3 Iowa games on the road.
• The 38.5 line has been covered in 13 of the last 20 Michigan games at home.

Over 38.5 Probability

The top sportsbooks imply that our pick has a 52.4% prospect of winning. However, our cappers think that the probability sits between 55-60% taking all factors into consideration. It's therefore regarded as a value wager.

If you want to get bigger odds on your Over wager, there’s a smart way of doing this. The top sportsbooks will allow you to move the line on the Totals.

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Our Game Prediction

Over 38.5 Points @ -110 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Sep 24, 22:25). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Hank Brown Over 155.5 Passing Yards -114

The odds for Hank Brown (Iowa) to go beyond 155.5 passing yards are -114. We believe it makes sense to stick with him on the Over and bettors can be confident in this QB Passing Yards pick.

Latest Hank Brown Player Prop Odds

Passing Yards

Over 155.5

-114

Under 155.5

-114

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Bryce Underwood Over 38.5 Rushing Yards -114

Bryce Underwood (Iowa) is priced at -114 to go over 38.5 rushing yards. With confidence, we can back him to cover the generous Player Rushing Yards line, as all the signs point to him reaching the expected total.

Latest Bryce Underwood Player Prop Odds

Passing Yards

Over 174.5

-114

Under 174.5

-114

Rushing Yards

Over 38.5

-114

Under 38.5

-114

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Iowa 23 - 21 Michigan

There are massive odds available when it comes to Iowa claiming a 23-21 victory. A close battle is anticipated between two evenly-matched teams.

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Iowa vs Michigan Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

For this college game, the sportsbooks’ Moneyline betting odds mean Michigan are -222 favorites to win and that means a 69% chance of landing a victory. Iowa are the underdogs at +180 and they’re regarded as least likely to win.

The spread is calculated to be 5.5, while total points comes in at 38.5. Having a bet on the Totals is one of the most popular football wagers. The Over 38.5 selection is available to back at -110.

You’ll find a great variety of team props and game lines for most college football showdowns. The best betting apps provide a strong mix of pre-game and in-game options to suit your betting style.

Moneyline

Iowa

+180

Michigan

-222

Point Spread

Iowa +5.5

-112

Michigan -5.5

-108

Total Points

Under 38.5

-110

Over 38.5

-110

Receiving Yards

JJ Buchanan (Michigan)

Over 58.5

-114

Under 58.5

-114

Tony Diaz (Iowa)

Over 54.5

-114

Under 54.5

-114

Andrew Marsh (Michigan)

Over 45.5

-114

Under 45.5

-114

Reece Vander Zee (Iowa)

Over 17.5

-114

Under 17.5

-114

Rushing Yards

Bryce Underwood (Michigan)

Over 38.5

-114

Under 38.5

-114

Passing Yards

Bryce Underwood (Michigan)

Over 174.5

-114

Under 174.5

-114

Hank Brown (Iowa)

Over 155.5

-114

Under 155.5

-114

Can Michigan Make It Another Home Victory?

Michigan have strung together three consecutive wins at Michigan Stadium. They have nine wins and one loss in the last 10 home games, averaging 30.70 points scored and 12.50 points allowed.

Iowa have five wins and five losses in the last 10 road games, averaging 27.30 points scored and 20.50 points allowed.

Michigan earned a 10-3 win against Iowa in the teams’ last meeting at Michigan Stadium.

Last 10 Games		W-L	P	PF	PA	O38.5	U38.5
Michigan Home Stats		9-1	43.20	30.70	12.50	4	6
Iowa Away Stats		5-5	47.80	27.30	20.50	7	3

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O38.5 = Games Over 38.5 Points
• U38.5 = Games Under 38.5 Points

Latest regular season and playoff games stats.

Iowa Hawkeyes Stats

Michigan Wolverines Stats

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 games on the road

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 9 wins and 1 defeat in the last 10 home games

Point Spread

• +5.5 Betting Line: Have covered the spread in the last 10 games
• +5.5 Betting Line on the Road: Have covered the spread in 9 of the last 10 games on the road

Point Spread

• -5.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -5.5 Betting Line at Home: Have covered the spread in 7 of the last 10 home games

Total Points

• Game Totals: An average of 45.20 pts in the previous 10 games
• Game Totals on the Road: An average of 47.80 pts in the previous 10 games on the road
• Over 38.5: Covered in 7 of the previous 10 games
• Over 38.5 on the Road: Covered in 7 of the previous 10 games on the road
• Team Totals: Have scored an average of 30.80 pts and allowed 14.40 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 27.30 pts and allowed 20.50 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 45.50 pts in the previous 10 games
• Game Totals at Home: An average of 40.80 pts in the previous 10 home games
• Over 38.5: Covered in 5 of the previous 10 games
• Over 38.5 at Home: Covered in 3 of the previous 10 home games
• Team Totals: Have scored an average of 26.30 pts and allowed 19.20 pts in the last 10 games
• Team Totals at Home: Have scored an average of 27.60 pts and allowed 13.20 pts in the last 10 home games

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