Notre Dame vs North Carolina Prediction, Picks & Odds | 03 Oct 2026
Notre Dame vs North Carolina Predictions
We like Notre Dame to win comfortably against North Carolina and cover the spread in the process. That’s why we’re backing the Irish at -21.5 on the spread at -110.
For Notre Dame vs North Carolina, our betting coverage includes our Best Bet, Same Game Parlay and Correct Score Prediction. Full breakdowns and the reasoning behind the picks are available below.
Notre Dame vs North Carolina Preview
No. 3 Notre Dame takes on North Carolina in this Week 5 game at Kenan Stadium, with kickoff scheduled for 12:00 on Saturday, October 3.
Notre Dame’s first matchup against an ACC opponent this season sends the Irish to Chapel Hill for a nationally televised road test. Bill Belichick facing one of college football’s premier programs provides the obvious headline, while Notre Dame has little room for a stumble with its national championship ambitions firmly established.
The Notre Dame Fighting Irish are 4-0 this season after making it four straight wins with a dominant 49-10 road victory over the Purdue Boilermakers. Quarterback CJ Carr completed 14 of 22 passes for 237 yards and three touchdowns while adding a rushing score. Aneyas Williams rushed for 80 yards and a touchdown as Notre Dame finished with 444 total yards.
The North Carolina Tar Heels are 2-1 after suffering their first defeat in a 28-20 road loss to the Clemson Tigers. Running back Benjamin Hall rushed for 130 yards on 18 carries and caught a 15-yard touchdown pass, while quarterback Billy Edwards Jr. threw for 135 yards and a score. North Carolina finished with 214 rushing yards.
H2H: Notre Dame 45-32 Victors When Teams Met Last
Notre Dame won the last meeting against North Carolina, earning a 45-32 victory at Kenan Stadium. The Irish have won each of the past five matchups between the teams.
Quarterbacks
CJ Carr
Billy Edwards Jr.
Best Bet
Notre Dame at -21.5 on the spread really stand out in this college football showdown. We are prepared to bet at odds of -110 and expect them to cover this line.
Key stats supporting our main match prediction:
Team news plays a key role in our college football forecasts and we’re always tracking players with injury concerns. We also stay on top of the form guide, supported by detailed stats that help paint a clearer picture of what to expect
Notre Dame -21.5 Probability
According to the top sportsbooks, our pick has a 52.4% chance of delivering a return. Taking all factors into consideration, our analysts think there’s a stronger chance of success and have a probability interval between 55-60%. It's why we think it’s worth placing this college wager.
If you want to land a big potential return from a small stake, then a Bet Builder could be a way to go. Bet on Notre Dame to cover the line in a combination with other selections.
Before your next wager, read our guide featuring today’s top betting offers, free bet deals, and sign-up bonuses.
Same Game Parlay Pick
We’ve loaded up a same game parlay with the combined picks of Notre Dame -21.5, Over 47.5 and the Second Half to feature most points.
A football same game parlay is a single event wager where you make predictions that are going to happen in a particular game. Should a bettor get these picks correct, then they can achieve a big return from a small stake.
Correct Score Prediction
38
-
13
North Carolina
A 38-13 win for the Irish is clearly a risky bet although this could be an exciting correct score option where there’s the chance to enjoy a massive potential return.
Notre Dame vs North Carolina Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
The sportsbooks are taking no chances with their Moneyline odds of -2000 about Notre Dame which reflects they have a 95% chance of winning this college game. For those wanting to back North Carolina, you will find +1000 about the underdogs.
The current spread is 21.5 and total points is 46.5. Football bettors regularly enjoy the opportunity to wager on the Totals. If you fancy Under 46.5, then the odds are -106.
The best betting apps provide tons of game lines and team props for nearly every college football matchup. Take a few moments to browse all the markets so you can place a bet that matches your insight.
Receiving Yards
Rushing Yards
Passing Yards
North Carolina Have Six Losses From Last Ten Home Games
North Carolina has a 4-6 record in their last 10 home games, averaging 25.60 points scored and 25.90 points allowed.
Notre Dame has strung together five consecutive road wins. They own a 9-1 mark in their past 10 games away from home, putting up 39.00 points per contest and giving up 17.80.
Notre Dame earned a 45-32 win over North Carolina the last time they played at Kenan Stadium.
| Last 10 Games | W-L | P | PF | PA | O47.5 | U47.5 | |
|---|---|---|---|---|---|---|---|
 North Carolina Home Stats |
4-6 | 51.50 | 25.60 | 25.90 | 6 | 4 | |
 Notre Dame Away Stats |
9-1 | 56.80 | 39.00 | 17.80 | 8 | 2 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O47.5 = Games Over 47.5 Points
- U47.5 = Games Under 47.5 Points
Latest regular season and playoff games stats.
Notre Dame Fighting Irish Stats
North Carolina Tar Heels Stats
- 10 wins and 0 defeats in the last 10 games
- 9 wins and 1 defeat in the last 10 games on the road
- -21.5 Betting Line: Have covered the spread in 7 of the last 10 games
- -21.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road
- +21.5 Betting Line: Have covered the spread in 9 of the last 10 games
- +21.5 Betting Line at Home: Have covered the spread in 8 of the last 10 home games
- Game Totals: An average of 55.20 pts in the previous 10 games
- Game Totals on the Road: An average of 56.80 pts in the previous 10 games on the road
- Over 47.5: Covered in 8 of the previous 10 games
- Over 47.5 on the Road: Covered in 8 of the previous 10 games on the road
- Team Totals: Have scored an average of 43.30 pts and allowed 11.90 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 39.00 pts and allowed 17.80 pts in the last 10 games on the road
- Game Totals: An average of 41.30 pts in the previous 10 games
- Game Totals at Home: An average of 48.10 pts in the previous 10 home games
- Over 47.5: Covered in 3 of the previous 10 games
- Over 47.5 at Home: Covered in 5 of the previous 10 home games
- Team Totals: Have scored an average of 20.70 pts and allowed 20.60 pts in the last 10 games
- Team Totals at Home: Have scored an average of 23.60 pts and allowed 24.50 pts in the last 10 home games
| Atlantic Coast | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Miami
|
5 | 0 | 248 | 49 | 199 | 2-0 | 3-0 | 5W |
Pittsburgh
|
5 | 0 | 192 | 67 | 125 | 4-0 | 1-0 | 5W |
Duke
|
4 | 0 | 145 | 44 | 101 | 3-0 | 1-0 | 4W |
California
|
2 | 3 | 135 | 133 | 2 | 1-2 | 1-1 | 2L |
SMU
|
4 | 1 | 173 | 115 | 58 | 3-0 | 1-1 | 2W |
Wake Forest
|
4 | 1 | 183 | 115 | 68 | 2-1 | 2-0 | 2W |
Virginia
|
3 | 2 | 169 | 90 | 79 | 3-1 | 0-1 | 1L |
NC State
|
3 | 2 | 184 | 128 | 56 | 3-0 | 0-2 | 2W |
Florida State
|
3 | 2 | 166 | 108 | 58 | 3-1 | 0-1 | 2W |
Virginia Tech
|
4 | 1 | 206 | 99 | 107 | 2-1 | 2-0 | 1L |
Louisville
|
2 | 3 | 193 | 146 | 47 | 2-1 | 0-2 | 2L |
Stanford
|
2 | 3 | 87 | 191 | -104 | 2-1 | 0-2 | 1L |
|
North Carolina
|
2 | 2 | 96 | 78 | 18 | 1-1 | 1-1 | 2L |
Clemson
|
3 | 2 | 97 | 129 | -32 | 2-1 | 1-1 | 1L |
Syracuse
|
2 | 2 | 139 | 92 | 47 | 1-1 | 1-1 | 1W |
Boston College
|
2 | 3 | 95 | 117 | -22 | 2-1 | 0-2 | 2L |
Georgia Tech
|
1 | 3 | 108 | 104 | 4 | 1-2 | 0-1 | 1L |
| Independents I-A | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
|
Notre Dame
|
5 | 0 | 206 | 59 | 147 | 3-0 | 2-0 | 5W |
UConn
|
2 | 3 | 180 | 131 | 49 | 1-2 | 1-1 | 2L |
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