USC vs Penn State Prediction, Picks & Odds | 10 Oct 2026
USC vs Penn State Predictions
We think that Penn State should prove too strong for USC. Therefore, it’s all about going to the Moneyline to back them and there’s juice in the -114 available.
Our experts have identified their Best Bet for USC vs Penn State, along with Player Props, a Same Game Parlay and Correct Score Prediction. Explore the complete analysis behind each pick further down the page.
USC vs Penn State Preview
USC square off against Penn State at Beaver Stadium, with kickoff scheduled for 19:30 on Saturday, October 10.
USC Trojans won their previous game which was at home. It was a 25-21 triumph at LA Memorial Coliseum against Washington Huskies.
Penn State Nittany Lions have been defeated in back-to-back games. On the road at Ryan Field, Northwestern Wildcats recently beat them 34-13.
H2H: Overtime Win for Penn State in Last H2H
The last head-to-head saw Penn State claim a 33-30 (OT) win over USC at LA Memorial Coliseum.
Quarterbacks
Jayden Maiava
Rocco Becht
Best Bet
For this college football matchup, we are going to bet against USC with our pick. One way of doing this is by siding with the opposition and we really like the -114 about the home team winning on the Moneyline.
Key stats supporting our main match prediction:
Tracking injury updates is a big part of our CFB analysis and team news plays a major role in shaping our picks. We combine this with recent form and the most important stats to get a complete picture.
Penn State Moneyline Probability
The best sportsbooks make it a 53.2% chance that our pick is settled as a winner. However, our cappers think that the probability is close to 60% taking all factors into consideration. This is why we can recommend this college wager.
Fancy Penn State to win but want more juice in the odds? Why not take a look at the spread and consider them to cover one of the available lines.
Don’t bet without checking our complete guide to the latest betting promo codes, free bets, and welcome bonuses.
Player Prop Picks
The odds for Jayden Maiava (USC) to end with fewer than 257.5 passing yards stand at -114. There’s a strong case for choosing him to fall short of the required line in the QB Passing Yards market.
Waymond Jordan (Penn State) is available at -114 to finish with fewer than 38.5 rushing yards. He is likely to fall short of the line, making this Player Rushing Yards bet an appealing option.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Pick
Our same game parlay pick includes Penn State on the moneyline, Over 54.5 and Jayden Maiava (USC) to go Under 257.5 passing yards.
We recommend a same game parlay as it’s a great way of betting on a single event. Many football bettors like to create a personalised wager which reflects their predictions for how a game is going to play out.
Correct Score Prediction
27
-
31
Penn State
There’s every chance that this is going to be a close matchup and we’ll have a play on the Lions achieving a 31-27 winning scoreline. Hopefully this can go close.
USC vs Penn State Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
The latest Moneyline odds are -114 that Penn State win, while USC have been chalked up at -105. The probability of the home team winning this college game is 53% according to the sportsbooks.
1.5 is the spread and 54.5 is the total points line. Having a bet on the Totals is one of the most popular football wagers. If you fancy Under 54.5, then the odds are -104.
The best betting apps offer a wide range of game lines and team props when it comes to most college football games. Make sure you look through all the available options before deciding which bet to place.
Receiving Yards
Rushing Yards
Passing Yards
Penn State Count Six Wins in Previous Ten at Home
Penn State own a 6-4 mark in their past 10 home games, averaging 35.80 points on offense and surrendering 14.30 on defense.
USC are 4-6 in their last 10 road games, averaging 27.40 points scored and 27.70 points allowed.
| Last 10 Games | W-L | P | PF | PA | O54.5 | U54.5 | |
|---|---|---|---|---|---|---|---|
 Penn State Home Stats |
6-4 | 50.10 | 35.80 | 14.30 | 3 | 7 | |
 USC Away Stats |
4-6 | 55.10 | 27.40 | 27.70 | 6 | 4 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O54.5 = Games Over 54.5 Points
- U54.5 = Games Under 54.5 Points
Latest regular season and playoff games stats.
USC Stats
Penn State Nittany Lions Stats
- 7 wins and 3 defeats in the last 10 games
- 4 wins and 6 defeats in the last 10 games on the road
- +1.5 Betting Line: Have covered the spread in 7 of the last 10 games
- +1.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road
- -1.5 Betting Line: Have covered the spread in 7 of the last 10 games
- -1.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games
- Game Totals: An average of 58.90 pts in the previous 10 games
- Game Totals on the Road: An average of 55.10 pts in the previous 10 games on the road
- Over 54.5: Covered in 6 of the previous 10 games
- Over 54.5 on the Road: Covered in 6 of the previous 10 games on the road
- Team Totals: Have scored an average of 33.30 pts and allowed 25.60 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 27.40 pts and allowed 27.70 pts in the last 10 games on the road
- Game Totals: An average of 48.40 pts in the previous 10 games
- Game Totals at Home: An average of 50.10 pts in the previous 10 home games
- Over 54.5: Covered in 2 of the previous 10 games
- Over 54.5 at Home: Covered in 3 of the previous 10 home games
- Team Totals: Have scored an average of 31.10 pts and allowed 17.30 pts in the last 10 games
- Team Totals at Home: Have scored an average of 35.80 pts and allowed 14.30 pts in the last 10 home games
| Big Ten | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Indiana
|
5 | 0 | 221 | 54 | 167 | 4-0 | 1-0 | 5W |
Ohio State
|
4 | 1 | 211 | 63 | 148 | 3-0 | 1-1 | 3W |
UCLA
|
4 | 0 | 179 | 75 | 104 | 2-0 | 2-0 | 4W |
Nebraska
|
5 | 0 | 218 | 71 | 147 | 4-0 | 1-0 | 5W |
Wisconsin
|
4 | 1 | 158 | 83 | 75 | 3-0 | 1-1 | 4W |
Minnesota
|
4 | 1 | 160 | 90 | 70 | 3-1 | 1-0 | 3W |
Oregon
|
3 | 1 | 190 | 93 | 97 | 2-0 | 1-1 | 2W |
|
USC
|
5 | 1 | 224 | 153 | 71 | 4-1 | 1-0 | 1W |
Iowa
|
4 | 1 | 145 | 63 | 82 | 3-1 | 1-0 | 1L |
Northwestern
|
3 | 1 | 132 | 67 | 65 | 3-0 | 0-1 | 1W |
Purdue
|
2 | 3 | 152 | 175 | -23 | 1-2 | 1-1 | 1W |
Michigan
|
3 | 2 | 115 | 79 | 36 | 3-1 | 0-1 | 2L |
|
Penn State
|
3 | 2 | 160 | 80 | 80 | 2-1 | 1-1 | 2L |
Washington
|
3 | 2 | 133 | 92 | 41 | 3-1 | 0-1 | 2L |
Illinois
|
2 | 3 | 153 | 130 | 23 | 2-2 | 0-1 | 2L |
Maryland
|
2 | 3 | 152 | 151 | 1 | 1-2 | 1-1 | 3L |
Michigan State
|
2 | 3 | 91 | 116 | -25 | 2-1 | 0-2 | 3L |
Rutgers
|
1 | 4 | 150 | 161 | -11 | 1-3 | 0-1 | 1L |
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