Wake Forest vs Purdue Prediction, Picks & Odds | 12 Sep 2026

College Football Betting Preview: Wake Forest vs Purdue

Wake Forest square off against Purdue at Ross-Ade Stadium, with kickoff scheduled for 12:00 on Saturday, September 12.

Wake Forest at -3.5 could be the best wager to have on the spread. -100 is available and our betting prediction is for the favorites to secure a solid victory when they meet Purdue.

Wake Forest Demon Deacons won their previous game which was at home. It was a 38-16 triumph at Allegacy Federal Credit Union Stadium against Akron Zips.

Purdue Boilermakers last game saw them claim a 44-19 home win over Indiana State Sycamores at Ross-Ade Stadium.

Wake Forest vs Purdue Prediction & Picks

This expert Wake Forest vs Purdue betting breakdown features our match prediction, a correct score pick and a carefully constructed bet builder to guide your wagers.

Game Prediction

We’re excited to see the favorites at -3.5 on the spread in this college football matchup. We think it’s a really good number for Wake Forest to cover at odds of -100.

Tracking injury updates is a big part of our CFB analysis and team news plays a major role in shaping our picks. We combine this with recent form and the most important stats to get a complete picture.

Key Wake Forest vs Purdue stats:

• The -3.5 line has been covered by Wake Forest in 4 of their last 5 games.
• The -3.5 line has been covered by Wake Forest in 7 of their last 10 games.
• The -3.5 line has been covered by Wake Forest in 2 consecutive games.
• The +3.5 line hasn’t been covered by Purdue in 8 of their last 10 games.
• The +3.5 line hasn’t been covered by Purdue in 4 of their last 5 games.

Wake Forest -3.5 Probability

According to the best betting apps, our pick has a 50% chance of winning. Based on our in-depth research, we calculate the actual probability to be closer to 60%. It is the reason why we are recommending this college wager.

It’s good to explore all avenues and you might prefer bigger odds about the selection you want to make. Go ahead and move the line until you’re happy with the price.

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Our Game Prediction

Wake Forest -3.5 @ -100 Bet Now

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Correct Score Prediction

Wake Forest 34 - 21 Purdue

A 34-21 win for the Demon Deacons is clearly a risky bet although this could be an exciting correct score option where there’s the chance to enjoy a massive potential return.

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Wake Forest vs Purdue Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Wake Forest are regarded as having a 62% chance of winning this college game according to the latest betting odds. The sportsbooks have priced them up at -161. Purdue are trading at bigger odds than their opponents and they can be backed at +134.

The spread currently stands at 3.5 and the total points line is 49.5. A wager on the Totals allows football bettors to use the latest data to good effect. Those who wager Under 49.5 can get -105.

Whether you are betting pre-game or in-game on college football, the best sportsbooks let you feast on a wide range of game lines and team props. The selections are practically endless, and it’s fantastic to have so many options.

Moneyline

Wake Forest

-161

Purdue

+134

Point Spread

Wake Forest -3.5

-100

Purdue +3.5

-122

Total Points

Under 49.5

-105

Over 49.5

-115

There is regularly value to be found from betting the quarterback and player props with the best online gambling sites. You can find lots of ways to back for or against a specific player lining up for one of the two teams.

Micro betting is an exciting way to wager on college football. There are a huge range of live lines and it’s a simple case of predicting what is going to happen next. Field Goal Outcome, Next Drive Result and Next Play Result are often among the options.

Purdue On Seven Losses From Previous Ten at Home

Purdue own a 3-7 mark in their past 10 home games, posting 22.00 points per contest while yielding 30.40.

Wake Forest are 6-4 in their last 10 games away from home, scoring 25.50 points per contest and conceding 28.30.

Last 10 Games		W-L	P	PF	PA	O49.5	U49.5
Purdue Home Stats		3-7	52.40	22.00	30.40	7	3
Wake Forest Away Stats		6-4	53.80	25.50	28.30	7	3

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O49.5 = Games Over 49.5 Points
• U49.5 = Games Under 49.5 Points

Latest regular season and playoff games stats.

Wake Forest Stats

Purdue Boilermakers Stats

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 1 win and 9 defeats in the last 10 games
• 3 wins and 7 defeats in the last 10 home games

Point Spread

• -3.5 Betting Line: Have covered the spread in 7 of the last 10 games
• -3.5 Betting Line on the Road: Have covered the spread in 4 of the last 10 games on the road

Point Spread

• +3.5 Betting Line: Have covered the spread in 2 of the last 10 games
• +3.5 Betting Line at Home: Have covered the spread in 4 of the last 10 home games

Total Points

• Game Totals: An average of 51.80 pts in the previous 10 games
• Game Totals on the Road: An average of 53.80 pts in the previous 10 games on the road
• Over 49.5: Covered in 6 of the previous 10 games
• Over 49.5 on the Road: Covered in 7 of the previous 10 games on the road
• Team Totals: Have scored an average of 29.80 pts and allowed 22.00 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 25.50 pts and allowed 28.30 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 53.80 pts in the previous 10 games
• Game Totals at Home: An average of 52.40 pts in the previous 10 home games
• Over 49.5: Covered in 6 of the previous 10 games
• Over 49.5 at Home: Covered in 7 of the previous 10 home games
• Team Totals: Have scored an average of 18.70 pts and allowed 35.10 pts in the last 10 games
• Team Totals at Home: Have scored an average of 22.00 pts and allowed 30.40 pts in the last 10 home games

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