Texans vs Colts Prediction, Picks & Odds | 27 Sep 2026

NFL Betting Preview: Texans vs Colts

The Houston Texans square off against the Indianapolis Colts in this Week 3 matchup at Lucas Oil Stadium, with kickoff scheduled for 13:00 on Sunday, September 27.

The -130 about the Texans beating the Colts makes lots of appeal and they are our betting prediction on the Moneyline. Hopefully this can secure a profit.

AFC South stakes give Houston’s trip to Indianapolis added importance, with two familiar rivals carrying postseason expectations into an early divisional test. C.J. Stroud faces a Colts defense featuring star cornerback Sauce Gardner, while Jonathan Taylor presents a major challenge for a talented Texans defense in a matchup that could eventually carry tiebreaker significance.

Houston Texans have been defeated in back-to-back games. They were recently beaten at home to Cincinnati Bengals by a 20-6 scoreline at NRG Stadium. The Texans generated 374 yards, including 314 passing and 60 rushing yards. They converted for 22 first downs and allowed 12.

Indianapolis Colts have suffered defeat in their last two games. Most recently, a 33-30 (OT) scoreline occurred on the road at GEHA Field at Arrowhead Stadium against Kansas City Chiefs. The Colts finished with 329 total yards, breaking down to 210 passing and 119 rushing yards. The offense scored 3 touchdowns and moved the chains 24 times.

Head-to-Head Statistics

The last matchup between the Texans and the Colts saw the former win. It was a 38-30 scoreline at NRG Stadium. Looking at the past 10 H2H clashes, there has been one draw. The Texans have won six games and the Colts three.

Quarterbacks

C.J. Stroud

239.5 Passing Yards

Over -114

Under -114

Daniel Jones

214.5 Passing Yards

Over -114

Under -114

Texans vs Colts Prediction & Picks

Our Texans vs Colts betting outlook has it all, including a trusted match forecast, our predicted score, top player prop picks and a hand-picked bet builder.

Game Prediction

We are eager to back the Texans to win this NFL matchup and that leads us to the Moneyline for our pick. It’s difficult to turn down the -130 that they claim the win.

Our NFL handicappers start by reviewing the latest team news for each franchise, followed by a close look at recent form. That information is then applied to the most relevant stats to reach a well-informed verdict.

Key Texans vs Colts stats:

• Texans have won 4 of their last 5 games on the road.
• Texans have won 7 of their last 10 games.
• Colts have lost their last 9 games.
• Colts have lost 11 of their last 20 games.
• Colts have lost their last 5 games against Texans.

Texans Moneyline Probability

The top betting sites imply that our pick has a 56.5% prospect of winning. Based on our analysts in-depth research, we calculate the actual probability to be 60-65%. It’s the reason why we are recommending this bet.

If you’re looking for bigger odds, then the Texans on the Double Result lines could be a good way forward. You need them to lead at the halfway stage and then claim a victory.

Explore the latest free bet promotions and welcome bonuses in our expert betting guide, updated with the best offers.

Our Game Prediction

Texans Moneyline @ -130 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Sep 25, 19:25). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: David Montgomery Anytime TD -110

David Montgomery (Texans) is priced at -110 to hit the end zone. There are appealing odds on offer for this Anytime Touchdown Scorer pick, and we believe it's an attractive wager for him to punch it in.

Latest David Montgomery Player Prop Odds

Touchdown

Anytime

-105

First

+550

Receiving Yards

Over 9.5

-114

Under 9.5

-114

Rushing Yards

Over 50.5

-114

Under 50.5

-114

---

C.J. Stroud Over 243.5 Passing Yards -114

C.J. Stroud (Texans) is available at -114 to go over 243.5 passing yards. We believe it makes sense to stick with him on the Over and bettors can be confident in this QB Passing Yards pick.

Latest C.J. Stroud Player Prop Odds

Touchdown

Anytime

+750

First

+3300

Passing Yards

Over 239.5

-114

Under 239.5

-114

Rushing Yards

Over 10.5

-114

Under 10.5

-114

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Texans 27 - 24 Colts

A close matchup could be on the cards. We’ll wager the Texans to secure a 27-24 win at massive odds and this correct score prediction should hopefully be a fun one.

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Texans vs Colts Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

There’s the opportunity to back Indianapolis Colts at +104 on the Moneyline although Houston Texans are priced up at betting odds of -122. If you want to know the probability of the road team winning this game, it’s 55% according to the most popular sportsbooks.

1.5 is where the spread lies, with total points being 42.5 right now. NFL fans regularly enjoy the opportunity to bet on the Totals. If you're keen on Over 42.5, this selection is available at -112.

The top NFL sportsbooks offer a huge selection of game lines and team props when it comes to this popular league. Make sure you look through all the available options before deciding which bet to place.

Moneyline

Texans

-122

Colts

+104

Point Spread

Texans -1.5

-112

Colts +1.5

-108

Total Points

Under 42.5

-108

Over 42.5

-112

The First TD Scorer favorite is Jonathan Taylor at +360. Similar odds can be found if you’re interested in this player to register the last touchdown.

Touchdown

Jonathan Taylor (Colts)

First TD

+360

Anytime TD

-149

David Montgomery (Texans)

First TD

+550

Anytime TD

-105

Tyler Warren (Colts)

First TD

+1100

Anytime TD

+230

Dalton Schultz (Texans)

First TD

+1200

Anytime TD

+220

Josh Downs (Colts)

First TD

+1200

Anytime TD

+270

Woody Marks (Texans)

First TD

+1200

Anytime TD

+260

Keenan Allen (Colts)

First TD

+1600

Anytime TD

+340

Kayshon Boutte (Texans)

First TD

+1600

Anytime TD

+300

Xavier Hutchinson (Texans)

First TD

+1800

Anytime TD

+370

Jaylin Noel (Texans)

First TD

+2200

Anytime TD

+460

Darius Slayton (Colts)

First TD

+2500

Anytime TD

+600

Daniel Jones (Colts)

First TD

+2700

Anytime TD

+650

Ashton Dulin (Colts)

First TD

+2700

Anytime TD

+700

Laquon Treadwell (Colts)

First TD

+3000

Anytime TD

+800

C.J. Stroud (Texans)

First TD

+3300

Anytime TD

+750

Jared Wayne (Texans)

First TD

+3500

Anytime TD

+750

Seth McGowan (Colts)

First TD

+4500

Anytime TD

+1000

DJ Giddens (Colts)

First TD

+4500

Anytime TD

+1000

Mo Alie-Cox (Colts)

First TD

+4500

Anytime TD

+1300

Nick Westbrook-Ikhine (Colts)

First TD

+4500

Anytime TD

+1300

Foster Moreau (Texans)

First TD

+5000

Anytime TD

+1000

Drew Ogletree (Colts)

First TD

+5500

Anytime TD

+1700

Deion Burks (Colts)

First TD

+8000

Anytime TD

+2500

Marlin Klein (Texans)

First TD

+8000

Anytime TD

+2200

Brevin Jordan (Texans)

First TD

+8000

Anytime TD

+2200

Cade Stover (Texans)

First TD

+8000

Anytime TD

+1800

Anthony Gould (Colts)

First TD

+8000

Anytime TD

+2500

British Brooks (Texans)

First TD

+10000

Anytime TD

+1900

Lewis Bond (Texans)

First TD

+10000

Anytime TD

+3300

Receiving Yards

Josh Downs (Colts)

Over 50.5

-114

Under 50.5

-114

Dalton Schultz (Texans)

Over 49.5

-114

Under 49.5

-114

Tyler Warren (Colts)

Over 46.5

-114

Under 46.5

-114

Xavier Hutchinson (Texans)

Over 38.5

-114

Under 38.5

-114

Kayshon Boutte (Texans)

Over 36.5

-114

Under 36.5

-114

Keenan Allen (Colts)

Over 32.5

-114

Under 32.5

-114

Jaylin Noel (Texans)

Over 27.5

-114

Under 27.5

-114

Jonathan Taylor (Colts)

Over 21.5

-114

Under 21.5

-114

Laquon Treadwell (Colts)

Over 16.5

-114

Under 16.5

-114

Jared Wayne (Texans)

Over 15.5

-114

Under 15.5

-114

Woody Marks (Texans)

Over 11.5

-114

Under 11.5

-114

David Montgomery (Texans)

Over 9.5

-114

Under 9.5

-114

Darius Slayton (Colts)

Over 8.5

-114

Under 8.5

-114

Rushing Yards

Jonathan Taylor (Colts)

Over 81.5

-114

Under 81.5

-114

David Montgomery (Texans)

Over 50.5

-114

Under 50.5

-114

Woody Marks (Texans)

Over 30.5

-114

Under 30.5

-114

C.J. Stroud (Texans)

Over 10.5

-114

Under 10.5

-114

Daniel Jones (Colts)

Over 9.5

-114

Under 9.5

-114

Passing Yards

C.J. Stroud (Texans)

Over 239.5

-114

Under 239.5

-114

Daniel Jones (Colts)

Over 214.5

-114

Under 214.5

-114

You don’t have to wait for the final outcome when it comes to NFL micro betting. Instead, there’s the opportunity to wager on live lines which tend to be settled in a shorter space of time and the in-game odds are always changing.

Colts On a Run of Four Home Defeats

The Colts have fallen to four defeats in succession at Lucas Oil Stadium. They own a 6-4 mark in their past 10 home games, averaging 28.00 points on offense and surrendering 23.80 on defense.

The Texans have six wins and four losses in the last 10 games away from home, putting up 20.40 points per contest and giving up 15.70.

In their last matchup at Lucas Oil Stadium, the Texans came out on top 20-16 against the Colts. Looking at the last 7 head-to-head matchups at Lucas Oil Stadium, the Texans have four victories and the Colts three.

Last 10 Games		W-L	P	PF	PA	O42.5	U42.5
Colts Home Stats		6-4	51.80	28.00	23.80	7	3
Texans Away Stats		6-4	36.10	20.40	15.70	3	7

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O42.5 = Games Over 42.5 Points
• U42.5 = Games Under 42.5 Points

Latest regular season and playoff games stats.

Houston Texans Stats

Indianapolis Colts Stats

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 1 win and 9 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 home games

Point Spread

• -1.5 Betting Line: Have covered the spread in 7 of the last 10 games
• -1.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road

Point Spread

• +1.5 Betting Line: Have covered the spread in 1 of the last 10 games
• +1.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games

Total Points

• Game Totals: An average of 44.70 pts in the previous 10 games
• Game Totals on the Road: An average of 36.10 pts in the previous 10 games on the road
• Over 42.5: Covered in 5 of the previous 10 games
• Over 42.5 on the Road: Covered in 3 of the previous 10 games on the road
• Team Totals: Have scored an average of 24.40 pts and allowed 20.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 20.40 pts and allowed 15.70 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 53.40 pts in the previous 10 games
• Game Totals at Home: An average of 52.50 pts in the previous 10 home games
• Over 42.5: Covered in 7 of the previous 10 games
• Over 42.5 at Home: Covered in 7 of the previous 10 home games
• Team Totals: Have scored an average of 22.90 pts and allowed 30.50 pts in the last 10 games
• Team Totals at Home: Have scored an average of 28.50 pts and allowed 24.00 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 340.60 Yds. Allowed 290.50 Yds
• Rushing Yards: Gained 106.40 Yds. Allowed 91.80 Yds
• Passing Yards: Gained 234.20 Yds. Allowed 198.70 Yds
• Total Touchdowns: Scored 2.40 TD. Allowed 2.40 TD
• Rushing Touchdowns: Scored 0.50 TD. Allowed 0.40 TD
• Passing Touchdowns: Scored 1.00 TD. Allowed 1.30 TD
• Total 1st Downs: Picked up 20.00. Allowed 15.90
• Total Turnovers: Committed 1.30. Committed by opponents 1.50
• Total Penalties: Committed 6.70. Committed by opponents 5.90
• Penalty Yards: Lost 62.50 Yds. Gained 51.30 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 300.50 Yds. Allowed 399.00 Yds
• Rushing Yards: Gained 109.30 Yds. Allowed 130.30 Yds
• Passing Yards: Gained 191.20 Yds. Allowed 268.70 Yds
• Total Touchdowns: Scored 2.50 TD. Allowed 2.90 TD
• Rushing Touchdowns: Scored 0.80 TD. Allowed 1.00 TD
• Passing Touchdowns: Scored 1.10 TD. Allowed 0.90 TD
• Total 1st Downs: Picked up 18.10. Allowed 23.50
• Total Turnovers: Committed 1.60. Committed by opponents 0.90
• Total Penalties: Committed 5.80. Committed by opponents 6.50
• Penalty Yards: Lost 46.10 Yds. Gained 61.50 Yds

Last 10 Games on the Road

• Total Yards: Gained 316.50 Yds. Allowed 259.20 Yds
• Rushing Yards: Gained 101.90 Yds. Allowed 83.20 Yds
• Passing Yards: Gained 214.60 Yds. Allowed 176.00 Yds
• Total Touchdowns: Scored 2.00 TD. Allowed 1.80 TD
• Rushing Touchdowns: Scored 0.30 TD. Allowed 0.70 TD
• Passing Touchdowns: Scored 1.20 TD. Allowed 0.90 TD
• Total 1st Downs: Picked up 18.70. Allowed 15.40
• Total Turnovers: Committed 1.70. Committed by opponents 1.90
• Total Penalties: Committed 7.20. Committed by opponents 6.50
• Penalty Yards: Lost 62.00 Yds. Gained 48.40 Yds

Last 10 Home Games

• Total Yards: Gained 355.00 Yds. Allowed 354.20 Yds
• Rushing Yards: Gained 137.10 Yds. Allowed 121.90 Yds
• Passing Yards: Gained 217.90 Yds. Allowed 232.30 Yds
• Total Touchdowns: Scored 3.40 TD. Allowed 2.80 TD
• Rushing Touchdowns: Scored 1.30 TD. Allowed 0.90 TD
• Passing Touchdowns: Scored 1.50 TD. Allowed 1.30 TD
• Total 1st Downs: Picked up 21.70. Allowed 22.00
• Total Turnovers: Committed 0.90. Committed by opponents 1.40
• Total Penalties: Committed 5.80. Committed by opponents 5.70
• Penalty Yards: Lost 47.00 Yds. Gained 55.90 Yds

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