Colts vs Jaguars Prediction, Picks & Odds | 07 Dec 2025

NFL Betting Preview: Colts vs Jaguars

The Indianapolis Colts go up against the Jacksonville Jaguars at EverBank Stadium, with kickoff scheduled for 13:00 on Sunday, December 7.

We think that the Colts should prove too strong for the Jaguars. Therefore, it’s all about going to the Moneyline to back the Shoe and there’s juice in the -123 available.

Indianapolis Colts suffered a second consecutive defeat when losing 20-16 in their previous game. This was at home to Houston Texans at Lucas Oil Stadium. The Colts recorded 281 yards, split between 195 passing and 86 rushing yards. They scored two touchdowns and picked up 17 first downs.

Jacksonville Jaguars got a third straight win in their last game. It was a 25-3 road triumph at Nissan Stadium when meeting Tennessee Titans. The Jaguars recorded 272 yards, with 202 through the air and 70 on the ground. They converted for 20 first downs and reached the end zone 3 times.

Head-to-Head Statistics

These two teams last met at Lucas Oil Stadium, with the Colts claiming the win. Beating the Jaguars by a 26-23 (OT) scoreline. The previous 10 games featuring these teams have resulted in six Jaguars victories.

Quarterbacks

Daniel Jones

221.5 Passing Yards

Over -112

Under -112

Trevor Lawrence

210.5 Passing Yards

Over -112

Under -112

Colts vs Jaguars Prediction & Picks

Prepare for Colts vs Jaguars with our expert betting guide featuring a trusted match prediction, likely scoreline, key player props and a well-crafted bet builder.

Game Prediction

The wager we really like for this NFL showdown is the Colts on the Moneyline. Our pick is trading at -123 and this looks great value out of all the options.

The NFL handicappers at Sportsgambler.com regularly track injury updates and pair that with current form. We also tap into a deep stats database to highlight the key numbers that help shape our predictions.

Key Colts vs Jaguars stats:

• Colts have won 8 of their last 12 games this season.
• Colts have won 6 of their last 10 games.

Colts Moneyline Probability

The top NFL sportsbooks make it a 55.2% chance that our pick is settled as a winner. Our analysts think there’s a stronger chance of success and calculate the probability to be 60-65%. It's therefore regarded as a value wager.

If you can correctly predict that the Colts will triumph along with the number of points, then you are able to combine the two picks and get bigger odds on the Result & Total lines.

Discover valuable betting promo codes, welcome offers, and free bets in our updated bonus guide before you play.

Our Game Prediction

Colts Moneyline @ -123 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Dec 5, 19:25). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Daniel Jones Over 230.5 Passing Yards -114

The odds for Daniel Jones (Colts) to exceed 230.5 passing yards are -114. We’re tempted to back him to cover the QB Passing Yards line, with plenty of juice on offer.

Latest Daniel Jones Player Prop Odds

Touchdown

Anytime

+650

First

+3000

Passing Yards

Over 221.5

-112

Under 221.5

-112

Rushing Yards

Over 5.5

-108

Under 5.5

-118

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Michael Pittman Jr. Anytime TD +195

Michael Pittman Jr. (Colts) is available at +195 to reach the goal line. We’ll take a chance with this Anytime Touchdown Scorer wager as the betting odds look really appealing.

Latest Michael Pittman Jr. Player Prop Odds

Touchdown

Anytime

+200

First

+1000

Receiving Yards

Over 45.5

-112

Under 45.5

-112

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Colts 27 - 24 Jaguars

There’s every chance that this is going to be a close battle and we’ll have a play on the Colts enjoying a 27-24 winning scoreline. Hopefully this can go close.

T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Colts vs Jaguars Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

When you consider the latest Moneyline odds, you can find Jacksonville Jaguars at -154 whereas Indianapolis Colts are +130. The hosts have a 61% chance of victory in the eyes of the leading sportsbooks.

The current spread is 3 and total points is 46.5. There is no denying the popularity of betting on the Totals. There’s the chance to back Under 46.5 at -110.

If you’re betting on the National Football League, we recommend visiting the top betting apps and scanning through the many team props and game lines. There’s the opportunity to wager pre-game and in-game.

Moneyline

Colts

+130

Jaguars

-154

Point Spread

Colts +3

-110

Jaguars -3

-110

Total Points

Under 46.5

-110

Over 46.5

-110

Those interested in Jonathan Taylor to score a touchdown at anytime are able to get -208. There is an opportunity to back the favorite to get the first TD at odds of +310.

Touchdown

Jonathan Taylor (Colts)

First TD

+310

Anytime TD

-208

Travis Etienne Jr. (Jaguars)

First TD

+700

Anytime TD

+115

Tyler Warren (Colts)

First TD

+900

Anytime TD

+170

Michael Pittman Jr. (Colts)

First TD

+1000

Anytime TD

+200

Alec Pierce (Colts)

First TD

+1100

Anytime TD

+230

Bhayshul Tuten (Jaguars)

First TD

+1200

Anytime TD

+195

Jakobi Meyers (Jaguars)

First TD

+1200

Anytime TD

+200

Brian Thomas Jr (Jaguars)

First TD

+1300

Anytime TD

+240

Josh Downs (Colts)

First TD

+1600

Anytime TD

+350

Brenton Strange (Jaguars)

First TD

+1700

Anytime TD

+330

Trevor Lawrence (Jaguars)

First TD

+2000

Anytime TD

+380

Parker Washington (Jaguars)

First TD

+2500

Anytime TD

+370

Tim Patrick (Jaguars)

First TD

+3000

Anytime TD

+500

Daniel Jones (Colts)

First TD

+3000

Anytime TD

+650

Dyami Brown (Jaguars)

First TD

+4000

Anytime TD

+650

Austin Trammell (Jaguars)

First TD

+4000

Anytime TD

+650

LeQuint Allen Jr. (Jaguars)

First TD

+5500

Anytime TD

+900

Cody Schrader (Jaguars)

First TD

+6000

Anytime TD

+900

Johnny Mundt (Jaguars)

First TD

+6500

Anytime TD

+1200

Ameer Abdullah (Colts)

First TD

+8000

Anytime TD

+1700

Drew Ogletree (Colts)

First TD

+10000

Anytime TD

+1400

Quintin Morris (Jaguars)

First TD

+10000

Anytime TD

+2200

Laquon Treadwell (Colts)

First TD

+10000

Anytime TD

+2500

Anthony Gould (Colts)

First TD

+10000

Anytime TD

+2500

Mo Alie-Cox (Colts)

First TD

+10000

Anytime TD

+2500

Tyler Goodson (Colts)

First TD

+10000

Anytime TD

+3300

Hunter Long (Jaguars)

First TD

+10000

Anytime TD

+2200

Will Mallory (Colts)

First TD

+10000

Anytime TD

+2500

DJ Giddens (Colts)

First TD

+10000

Anytime TD

+3300

Receiving Yards

Alec Pierce (Colts)

Over 51.5

-112

Under 51.5

-112

Jakobi Meyers (Jaguars)

Over 51.5

-112

Under 51.5

-112

Tyler Warren (Colts)

Over 50.5

-112

Under 50.5

-112

Michael Pittman Jr. (Colts)

Over 45.5

-112

Under 45.5

-112

Brian Thomas Jr (Jaguars)

Over 43.5

-112

Under 43.5

-112

Brenton Strange (Jaguars)

Over 38.5

-112

Under 38.5

-112

Josh Downs (Colts)

Over 33.5

-112

Under 33.5

-112

Jonathan Taylor (Colts)

Over 17.5

-112

Under 17.5

-112

Travis Etienne Jr. (Jaguars)

Over 13.5

-112

Under 13.5

-112

Rushing Yards

Jonathan Taylor (Colts)

Over 93.5

-112

Under 93.5

-112

Travis Etienne Jr. (Jaguars)

Over 53.5

-112

Under 53.5

-112

Bhayshul Tuten (Jaguars)

Over 25.5

-112

Under 25.5

-112

Trevor Lawrence (Jaguars)

Over 15.5

-112

Under 15.5

-112

Daniel Jones (Colts)

Over 5.5

-108

Under 5.5

-118

Passing Yards

Daniel Jones (Colts)

Over 221.5

-112

Under 221.5

-112

Trevor Lawrence (Jaguars)

Over 210.5

-112

Under 210.5

-112

Micro betting is something that’s really popular with bettors, with NFL fans essentially being able to wager in-game when it comes to score, player and team props. Sometimes these are two-way lines where you can bet on the Next Play or Next Drive.

Jaguars Have Won Last Six Head-to-Head Meetings at EverBank Stadium

The Jaguars have five wins and five losses in the last 10 games at home, averaging 22.60 points scored and 19.00 points allowed.

The Colts own a 4-6 mark in their past 10 games on the road, scoring 25.10 points per contest and conceding 26.90.

The Jaguars defeated the Colts 37-34 when the teams last met at EverBank Stadium. Across the previous 6 head-to-head meetings at EverBank Stadium, the Jaguars have prevailed every time.

Last 10 Games		W-L	P	PF	PA	O46.5	U46.5
Jaguars Home Stats		8-2	44.30	30.80	13.50	4	6
Colts Away Stats		2-8	49.70	23.50	26.20	6	4

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O46.5 = Games Over 46.5 Points
• U46.5 = Games Under 46.5 Points

Latest regular season and playoff games stats.

Indianapolis Colts Stats

Jacksonville Jaguars Stats

Moneyline

• 2 wins and 8 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +10.5 Betting Line: Have covered the spread in 7 of the last 10 games
• +10.5 Betting Line on the Road: Have covered the spread in 8 of the last 10 games on the road

Point Spread

• -10.5 Betting Line: Have covered the spread in 4 of the last 10 games
• -10.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games

Total Points

• Game Totals: An average of 51.70 pts in the previous 10 games
• Game Totals on the Road: An average of 49.70 pts in the previous 10 games on the road
• Over 46.5: Covered in 5 of the previous 10 games
• Over 46.5 on the Road: Covered in 6 of the previous 10 games on the road
• Team Totals: Have scored an average of 22.80 pts and allowed 28.90 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 23.50 pts and allowed 26.20 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 45.10 pts in the previous 10 games
• Game Totals at Home: An average of 49.10 pts in the previous 10 home games
• Over 46.5: Covered in 4 of the previous 10 games
• Over 46.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 27.60 pts and allowed 17.50 pts in the last 10 games
• Team Totals at Home: Have scored an average of 31.00 pts and allowed 18.10 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 295.60 Yds. Allowed 353.10 Yds
• Rushing Yards: Gained 102.60 Yds. Allowed 127.10 Yds
• Passing Yards: Gained 193.00 Yds. Allowed 226.00 Yds
• Total Touchdowns: Scored 2.20 TD. Allowed 2.90 TD
• Rushing Touchdowns: Scored 0.50 TD. Allowed 0.30 TD
• Passing Touchdowns: Scored 0.60 TD. Allowed 0.80 TD
• Total 1st Downs: Picked up 18.90. Allowed 19.60
• Total Turnovers: Committed 1.90. Committed by opponents 0.60
• Total Penalties: Committed 5.40. Committed by opponents 6.30
• Penalty Yards: Lost 44.20 Yds. Gained 56.60 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 348.00 Yds. Allowed 325.90 Yds
• Rushing Yards: Gained 109.70 Yds. Allowed 75.90 Yds
• Passing Yards: Gained 238.30 Yds. Allowed 250.00 Yds
• Total Touchdowns: Scored 3.20 TD. Allowed 1.90 TD
• Rushing Touchdowns: Scored 0.40 TD. Allowed 0.60 TD
• Passing Touchdowns: Scored 1.30 TD. Allowed 0.60 TD
• Total 1st Downs: Picked up 21.50. Allowed 18.20
• Total Turnovers: Committed 0.80. Committed by opponents 1.50
• Total Penalties: Committed 6.00. Committed by opponents 7.80
• Penalty Yards: Lost 51.70 Yds. Gained 59.90 Yds

Last 10 Games on the Road

• Total Yards: Gained 301.40 Yds. Allowed 363.40 Yds
• Rushing Yards: Gained 97.80 Yds. Allowed 104.20 Yds
• Passing Yards: Gained 203.60 Yds. Allowed 259.20 Yds
• Total Touchdowns: Scored 2.30 TD. Allowed 2.30 TD
• Rushing Touchdowns: Scored 0.80 TD. Allowed 0.60 TD
• Passing Touchdowns: Scored 0.80 TD. Allowed 0.80 TD
• Total 1st Downs: Picked up 18.80. Allowed 20.40
• Total Turnovers: Committed 1.70. Committed by opponents 0.70
• Total Penalties: Committed 5.50. Committed by opponents 6.90
• Penalty Yards: Lost 45.80 Yds. Gained 55.70 Yds

Last 10 Home Games

• Total Yards: Gained 366.40 Yds. Allowed 275.60 Yds
• Rushing Yards: Gained 118.60 Yds. Allowed 81.20 Yds
• Passing Yards: Gained 247.80 Yds. Allowed 194.40 Yds
• Total Touchdowns: Scored 3.90 TD. Allowed 2.00 TD
• Rushing Touchdowns: Scored 0.80 TD. Allowed 0.70 TD
• Passing Touchdowns: Scored 1.90 TD. Allowed 1.00 TD
• Total 1st Downs: Picked up 22.50. Allowed 17.00
• Total Turnovers: Committed 0.80. Committed by opponents 1.50
• Total Penalties: Committed 6.20. Committed by opponents 6.70
• Penalty Yards: Lost 52.50 Yds. Gained 53.70 Yds

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