Raiders vs Chargers Prediction, Picks & Odds | 20 Sep 2026

NFL Betting Preview: Raiders vs Chargers

The Las Vegas Raiders face the Los Angeles Chargers at SoFi Stadium, with kickoff scheduled for 16:05 on Sunday, September 20.

The -110 for Under 43.5 points to be scored by the two teams looks like great value. Our prediction is that the Chargers and the Raiders might not collectively reach this total.

The AFC West rarely needs much help generating tension, and Raiders-Chargers brings divisional stakes to Los Angeles early in the season. Justin Herbert leads a Chargers team with postseason expectations, while Las Vegas arrives with Kirk Cousins at quarterback and the opportunity to make an early mark in one of the league's toughest divisions.

Las Vegas Raiders opened the Klint Kubiak era with a 27-13 home win against Miami Dolphins at Allegiant Stadium. Las Vegas generated 290 total yards, including 160 net passing yards and 130 on the ground, while recording 21 first downs and scoring three touchdowns.

Ashton Jeanty led the way with 147 yards from scrimmage on 29 touches, including 102 rushing yards, and caught two touchdown passes. Kirk Cousins completed 21 of 30 passes for 160 yards and three touchdowns, although he was intercepted twice.

Los Angeles Chargers began their season with a 26-14 home defeat against Arizona Cardinals at SoFi Stadium. Los Angeles finished with 268 total yards, including 187 net passing yards and 81 rushing yards, while recording 17 first downs and scoring two touchdowns.

Justin Herbert completed 17 of 27 passes for 209 yards and a touchdown with one interception, while also rushing for 29 yards. The Chargers struggled to sustain drives, converting just two of eight third-down opportunities, with Herbert also taking three sacks for 22 yards.

Head-to-Head Statistics

The last head-to-head saw the Chargers claim a 31-14 win over the Raiders at SoFi Stadium. In the past 10 H2H meetings, the Chargers have won seven.

Quarterbacks

Kirk Cousins

192.5 Passing Yards

Over -114

Under -114

Justin Herbert

223.5 Passing Yards

Over -114

Under -114

Raiders vs Chargers Prediction & Picks

Get ahead of the game with our Raiders vs Chargers betting rundown, featuring our trusted match prediction, likely score outcome, standout player prop plays and a fully loaded bet builder.

Game Prediction

The Unders looks the way to go for this NFL matchup. The line looks too high at 43.5 and odds of -110 could favor bettors who go below that total.

Tracking injury updates is a big part of our analysis and team news plays a major role in shaping our NFL predictions. We combine this with recent form and the most important stats to get a complete picture.

Key Raiders vs Chargers stats:

• The 43.5 line hasn’t been covered in 6 of the last 10 Raiders games.
• The 43.5 line hasn’t been covered in 3 of the last 5 Raiders games.
• The 43.5 line hasn’t been covered in the last 2 Raiders games.
• The 43.5 line hasn’t been covered in the last 4 Chargers games.
• The 43.5 line hasn’t been covered in 8 of the last 10 Chargers games.
• The 43.5 line hasn’t been covered in 12 of the last 20 Chargers games.

Under 43.5 Probability

The best betting apps imply that our pick has a 52.4% chance of winning. Taking all factors into consideration, our analysts think there’s a stronger chance of success and estimate the probability to be closer to 60%. It’s why we think it’s worth placing this wager.

More juice from your Unders wager can be found by combining this pick on the Result & Total lines. Choose the price which match your prediction.

Get more from your wager using our bonus guide, which highlights top betting offers, free bets, and welcome promotions.

Our Game Prediction

Under 43.5 Points @ -110 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Sep 18, 22:25). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Quentin Johnston Anytime TD +130

Quentin Johnston (Chargers) is available at +130 to record a TD. Based on all the evidence, we're happy to back him to punch it in on the Anytime Touchdown Scorer market.

Latest Quentin Johnston Player Prop Odds

Touchdown

Anytime

+185

First

+900

Receiving Yards

Over 46.5

-114

Under 46.5

-114

---

Omarion Hampton Under 62.5 Rushing Yards -114

You can back Omarion Hampton (Raiders) at -114 to finish with fewer than 62.5 rushing yards. Several factors suggest he will fall short of the Player Rushing Yards line, making this an appealing wager.

Latest Omarion Hampton Player Prop Odds

Touchdown

Anytime

-154

First

+380

Receiving Yards

Over 10.5

-114

Under 10.5

-114

Rushing Yards

Over 62.5

-114

Under 62.5

-114

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Raiders 13 - 21 Chargers

There are some big returns lying in wait if you can get the correct score right. With this in mind, we’ll have a play on the Chargers to enjoy a 21-13 winning scoreline.

T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Raiders vs Chargers Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

With a 76% chance of securing victory, Los Angeles Chargers are favorites for this game and the sportsbooks have them at betting odds of -312. Las Vegas Raiders are the underdogs at +250 and they’re regarded as least likely to win.

6.5 is the spread and 43.5 is the total points line. NFL bettors love the chance to get an alternative angle by going for a Total wager. If you want to bet Under 43.5, there are odds of -110.

If you’re planning to place a bet on a National Football League matchup, visit the top sportsbooks and check out the hundreds of available game lines and team props. Find the betting lines and odds which are the most attractive.

Moneyline

Raiders

+250

Chargers

-312

Point Spread

Raiders +6.5

-105

Chargers -6.5

-115

Total Points

Under 43.5

-110

Over 43.5

-110

Omarion Hampton is priced at +380 when it comes to First TD Scorer. He’s the favorite and also available at odds of -154 to score a touchdown at anytime.

Touchdown

Omarion Hampton (Chargers)

First TD

+380

Anytime TD

-154

Ashton Jeanty (Raiders)

First TD

+600

Anytime TD

-100

Quentin Johnston (Chargers)

First TD

+900

Anytime TD

+185

Ladd McConkey (Chargers)

First TD

+1100

Anytime TD

+230

Tre Harris (Chargers)

First TD

+1400

Anytime TD

+310

Brock Bowers (Raiders)

First TD

+1400

Anytime TD

+230

Michael Mayer (Raiders)

First TD

+1600

Anytime TD

+250

David Njoku (Chargers)

First TD

+1900

Anytime TD

+420

Tre Tucker (Raiders)

First TD

+1900

Anytime TD

+350

Justin Herbert (Chargers)

First TD

+2000

Anytime TD

+470

Jalen Nailor (Raiders)

First TD

+2000

Anytime TD

+420

Oronde Gadsden II (Chargers)

First TD

+2000

Anytime TD

+500

Keaton Mitchell (Chargers)

First TD

+2000

Anytime TD

+470

Mike Washington Jr. (Raiders)

First TD

+2700

Anytime TD

+600

Charlie Kolar (Chargers)

First TD

+2700

Anytime TD

+700

Jack Bech (Raiders)

First TD

+3500

Anytime TD

+750

Kimani Vidal (Chargers)

First TD

+3500

Anytime TD

+800

Malik Benson (Raiders)

First TD

+5000

Anytime TD

+1100

Brenen Thompson (Chargers)

First TD

+6000

Anytime TD

+1600

Derius Davis (Chargers)

First TD

+6000

Anytime TD

+1500

Connor Heyward (Raiders)

First TD

+7000

Anytime TD

+1700

Ian Thomas (Raiders)

First TD

+7500

Anytime TD

+1600

Dylan Laube (Raiders)

First TD

+8000

Anytime TD

+2000

Gary Jennings (Chargers)

First TD

+8000

Anytime TD

+2200

Kirk Cousins (Raiders)

First TD

+8000

Anytime TD

+2200

Dareke Young (Raiders)

First TD

+8000

Anytime TD

+2200

Alec Ingold (Chargers)

First TD

+10000

Anytime TD

+2500

Cody White (Raiders)

First TD

+10000

Anytime TD

+2500

Chris Myarick (Raiders)

First TD

+10000

Anytime TD

+2200

Receiving Yards

Quentin Johnston (Chargers)

Over 46.5

-114

Under 46.5

-114

Michael Mayer (Raiders)

Over 43.5

-114

Under 43.5

-114

Ladd McConkey (Chargers)

Over 42.5

-114

Under 42.5

-114

Tre Tucker (Raiders)

Over 36.5

-114

Under 36.5

-114

Jalen Nailor (Raiders)

Over 32.5

-114

Under 32.5

-114

Tre Harris (Chargers)

Over 30.5

-114

Under 30.5

-114

Ashton Jeanty (Raiders)

Over 26.5

-114

Under 26.5

-114

David Njoku (Chargers)

Over 23.5

-114

Under 23.5

-114

Oronde Gadsden II (Chargers)

Over 12.5

-114

Under 12.5

-114

Omarion Hampton (Chargers)

Over 10.5

-114

Under 10.5

-114

Rushing Yards

Ashton Jeanty (Raiders)

Over 62.5

-114

Under 62.5

-114

Omarion Hampton (Chargers)

Over 62.5

-114

Under 62.5

-114

Keaton Mitchell (Chargers)

Over 23.5

-114

Under 23.5

-114

Justin Herbert (Chargers)

Over 19.5

-114

Under 19.5

-114

Mike Washington Jr. (Raiders)

Over 18.5

-114

Under 18.5

-114

Kirk Cousins (Raiders)

Over 0.5

+136

Under 0.5

-175

Passing Yards

Justin Herbert (Chargers)

Over 223.5

-114

Under 223.5

-114

Kirk Cousins (Raiders)

Over 192.5

-114

Under 192.5

-114

It’s good to consider all wagering options when it comes to NFL and micro betting can be an exciting way to get involved in the action. When everything goes in-game, consider whether a player will make or miss a field goal.

Chargers Have Won the Previous Five Head-to-Head Matchups at SoFi Stadium

The Chargers have gone 6-4 across their last 10 home games, putting up 22.90 points per contest and giving up 20.50.

The Raiders are on a skid of seven straight road defeats. They have two wins and eight losses in the last 10 games away from home, averaging 13.00 points on offense and surrendering 25.80 on defense.

When the teams last met at SoFi Stadium, the Chargers beat the Raiders 31-14. Over the previous 6 head-to-head clashes at SoFi Stadium, the Chargers have collected five victories, while the Raiders have one.

Last 10 Games		W-L	P	PF	PA	O43.5	U43.5
Chargers Home Stats		6-4	43.40	22.90	20.50	4	6
Raiders Away Stats		2-8	38.80	13.00	25.80	4	6

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O43.5 = Games Over 43.5 Points
• U43.5 = Games Under 43.5 Points

Latest regular season and playoff games stats.

Las Vegas Raiders Stats

Los Angeles Chargers Stats

Moneyline

• 2 wins and 8 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 home games

Point Spread

• +6.5 Betting Line: Have covered the spread in 4 of the last 10 games
• +6.5 Betting Line on the Road: Have covered the spread in 4 of the last 10 games on the road

Point Spread

• -6.5 Betting Line: Have covered the spread in 3 of the last 10 games
• -6.5 Betting Line at Home: Have covered the spread in 3 of the last 10 home games

Total Points

• Game Totals: An average of 37.10 pts in the previous 10 games
• Game Totals on the Road: An average of 38.80 pts in the previous 10 games on the road
• Over 43.5: Covered in 4 of the previous 10 games
• Over 43.5 on the Road: Covered in 4 of the previous 10 games on the road
• Team Totals: Have scored an average of 13.60 pts and allowed 23.50 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 13.00 pts and allowed 25.80 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 35.90 pts in the previous 10 games
• Game Totals at Home: An average of 43.40 pts in the previous 10 home games
• Over 43.5: Covered in 2 of the previous 10 games
• Over 43.5 at Home: Covered in 4 of the previous 10 home games
• Team Totals: Have scored an average of 17.00 pts and allowed 18.90 pts in the last 10 games
• Team Totals at Home: Have scored an average of 22.90 pts and allowed 20.50 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 219.20 Yds. Allowed 299.50 Yds
• Rushing Yards: Gained 73.40 Yds. Allowed 118.50 Yds
• Passing Yards: Gained 145.80 Yds. Allowed 181.00 Yds
• Total Touchdowns: Scored 1.40 TD. Allowed 2.60 TD
• Rushing Touchdowns: Scored 0.20 TD. Allowed 1.00 TD
• Passing Touchdowns: Scored 0.90 TD. Allowed 1.20 TD
• Total 1st Downs: Picked up 14.00. Allowed 18.20
• Total Turnovers: Committed 1.20. Committed by opponents 1.00
• Total Penalties: Committed 6.20. Committed by opponents 6.70
• Penalty Yards: Lost 51.10 Yds. Gained 51.00 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 277.90 Yds. Allowed 304.20 Yds
• Rushing Yards: Gained 111.90 Yds. Allowed 106.60 Yds
• Passing Yards: Gained 166.00 Yds. Allowed 197.60 Yds
• Total Touchdowns: Scored 1.60 TD. Allowed 1.80 TD
• Rushing Touchdowns: Scored 0.60 TD. Allowed 0.60 TD
• Passing Touchdowns: Scored 0.80 TD. Allowed 0.90 TD
• Total 1st Downs: Picked up 16.90. Allowed 17.80
• Total Turnovers: Committed 1.20. Committed by opponents 1.70
• Total Penalties: Committed 5.20. Committed by opponents 4.80
• Penalty Yards: Lost 42.60 Yds. Gained 46.20 Yds

Last 10 Games on the Road

• Total Yards: Gained 254.20 Yds. Allowed 339.40 Yds
• Rushing Yards: Gained 82.30 Yds. Allowed 128.40 Yds
• Passing Yards: Gained 171.90 Yds. Allowed 211.00 Yds
• Total Touchdowns: Scored 1.40 TD. Allowed 3.20 TD
• Rushing Touchdowns: Scored 0.40 TD. Allowed 0.90 TD
• Passing Touchdowns: Scored 1.00 TD. Allowed 1.80 TD
• Total 1st Downs: Picked up 14.20. Allowed 19.80
• Total Turnovers: Committed 1.00. Committed by opponents 1.00
• Total Penalties: Committed 6.20. Committed by opponents 6.60
• Penalty Yards: Lost 56.60 Yds. Gained 52.40 Yds

Last 10 Home Games

• Total Yards: Gained 344.30 Yds. Allowed 306.30 Yds
• Rushing Yards: Gained 124.30 Yds. Allowed 100.50 Yds
• Passing Yards: Gained 220.00 Yds. Allowed 205.80 Yds
• Total Touchdowns: Scored 2.40 TD. Allowed 2.10 TD
• Rushing Touchdowns: Scored 0.60 TD. Allowed 0.80 TD
• Passing Touchdowns: Scored 1.60 TD. Allowed 1.10 TD
• Total 1st Downs: Picked up 21.20. Allowed 16.60
• Total Turnovers: Committed 1.40. Committed by opponents 1.30
• Total Penalties: Committed 6.20. Committed by opponents 6.80
• Penalty Yards: Lost 46.60 Yds. Gained 63.00 Yds

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