Chargers vs Chiefs Prediction, Picks & Odds | 14 Dec 2025

NFL Betting Preview: Chargers vs Chiefs

The Los Angeles Chargers go up against the Kansas City Chiefs at GEHA Field at Arrowhead Stadium, with kickoff scheduled for 13:00 on Sunday, December 14.

It’s time to go for the Chiefs against the spread, especially with an attractive -5.5 line at -110. Our prediction is that this can be comfortably achieved in their meeting with the Chargers.

Los Angeles Chargers claimed a home victory in their previous game. A 22-19 (OT) triumph against Philadelphia Eagles at SoFi Stadium made it back-to-back wins. The Chargers moved the ball for 275 yards, breaking down to 106 passing and 169 rushing yards. The offense scored one passing TD and moved the chains 16 times.

Kansas City Chiefs were defeated last time, making it back-to-back losses. GEHA Field at Arrowhead Stadium saw them beaten 20-10 at home to Houston Texans. The Chiefs finished with 274 total yards, breaking down to 148 passing and 126 rushing yards. The offense picked up 15 first downs and reached the end zone once.

Head-to-Head Statistics

The last head-to-head saw the Chargers claim a 27-21 win over the Chiefs at SoFi Stadium. The previous 10 games featuring these teams have resulted in seven Chiefs victories.

Quarterbacks

Justin Herbert

202.5 Passing Yards

Over -112

Under -112

Patrick Mahomes

236.5 Passing Yards

Over -112

Under -112

Chargers vs Chiefs Prediction & Picks

From our main match prediction to correct score advice, must-watch player props and a custom bet builder — this Chargers vs Chiefs betting preview covers it all.

Game Prediction

The Chiefs are capable of covering the -5.5 line. We’re confident of a strong showing in this NFL showdown and a wager against the spread is the best play at -110.

We track all injuries that could impact each franchise before making our NFL predictions. The form guide and latest stats also help the Sportsgambler.com team crunch the numbers ahead of the action.

Key Chargers vs Chiefs stats:

• The -5.5 line has been covered by Chiefs in 6 of their last 10 games at home.
• The -5.5 line has been covered by Chiefs in 3 of their last 5 games at home.

Chiefs -5.5 Probability

When you look at the latest betting odds, our pick has a 52.4% chance of winning. However, our analysts research has found that the actual probability is closer to 60%. The wager can be recommended for this precise reason.

If you want to land bigger odds, you might be interested to know that you can move the line. There’s extra juice depending on how risky you want your wager to be.

Thinking about placing a wager? Explore our updated guide filled with top betting offers, free bets, and promotions.

Our Game Prediction

Chiefs -5.5 @ -110 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Dec 12, 19:25). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Kareem Hunt Anytime TD +110

Kareem Hunt (Chiefs) is available at +110 to record a TD. We’ll have a play on this Anytime Touchdown Scorer wager as the betting odds look pretty attractive.

Latest Kareem Hunt Player Prop Odds

Touchdown

Anytime

+115

First

+600

Receiving Yards

Over 7.5

-112

Under 7.5

-112

Rushing Yards

Over 36.5

-112

Under 36.5

-112

---

Travis Kelce Over 43.5 Receiving Yards -114

You can back Travis Kelce (Chargers) at -114 to go over 43.5 receiving yards. There’s an opportunity to place a Player Receiving Yards bet, with him capable of covering an appealing line.

Latest Travis Kelce Player Prop Odds

Touchdown

Anytime

+220

First

+900

Receiving Yards

Over 39.5

-112

Under 39.5

-112

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Chargers 21 - 30 Chiefs

Correct score betting might be tough to predict but there’s a huge potential return if you get it right. We’ll try the Chiefs to achieve a 30-21 victory at monster odds.

T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Chargers vs Chiefs Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The Kansas City Chiefs odds have been priced up by the sportsbooks and they are -192 betting favorites to land victory in this game which means a 66% chance of winning. If you’re looking for an alternative angle, Los Angeles Chargers are trading at +160.

4.5 is where the spread lies, with total points being 45.5 right now. The Totals offers NFL fans an alternative way of getting involved. There’s the chance to back Under 45.5 at -110.

Whether you're placing bets before kickoff or during the game, the best NFL sportsbooks delivers a massive range of game lines and team props. The betting sites give you endless ways to get involved with plenty of exciting alternatives.

Moneyline

Chargers

+160

Chiefs

-192

Point Spread

Chargers +4.5

-110

Chiefs -4.5

-110

Total Points

Under 45.5

-110

Over 45.5

-110

You will find Rashee Rice at +500 to be First Touchdown Scorer which makes him the favorite. There’s the chance to get +105 that he scores a TD at anytime.

Touchdown

Rashee Rice (Chiefs)

First TD

+500

Anytime TD

+105

Kareem Hunt (Chiefs)

First TD

+600

Anytime TD

+115

Omarion Hampton (Chargers)

First TD

+800

Anytime TD

+165

Travis Kelce (Chiefs)

First TD

+900

Anytime TD

+220

Ladd McConkey (Chargers)

First TD

+1100

Anytime TD

+230

Xavier Worthy (Chiefs)

First TD

+1200

Anytime TD

+300

Oronde Gadsden II (Chargers)

First TD

+1300

Anytime TD

+290

Quentin Johnston (Chargers)

First TD

+1500

Anytime TD

+320

Keenan Allen (Chargers)

First TD

+1500

Anytime TD

+320

Patrick Mahomes (Chiefs)

First TD

+1600

Anytime TD

+410

Isiah Pacheco (Chiefs)

First TD

+1700

Anytime TD

+420

Tre Harris (Chargers)

First TD

+2200

Anytime TD

+480

Kimani Vidal (Chargers)

First TD

+2500

Anytime TD

+500

Marquise Brown (Chiefs)

First TD

+2700

Anytime TD

+800

JuJu Smith-Schuster (Chiefs)

First TD

+2700

Anytime TD

+800

Noah Gray (Chiefs)

First TD

+2700

Anytime TD

+750

Justin Herbert (Chargers)

First TD

+3000

Anytime TD

+700

Tyquan Thornton (Chiefs)

First TD

+3000

Anytime TD

+750

Will Dissly (Chargers)

First TD

+6000

Anytime TD

+1000

Tyler Conklin (Chargers)

First TD

+6000

Anytime TD

+1000

Brashard Smith (Chiefs)

First TD

+8000

Anytime TD

+1500

Elijah Mitchell (Chiefs)

First TD

+8000

Anytime TD

+1500

Jared Wiley (Chiefs)

First TD

+10000

Anytime TD

+4000

Robert Tonyan (Chiefs)

First TD

+10000

Anytime TD

+4000

KeAndre Lambert-Smith (Chargers)

First TD

+10000

Anytime TD

+1600

Scott Matlock (Chargers)

First TD

+10000

Anytime TD

+3000

Hassan Haskins (Chargers)

First TD

+10000

Anytime TD

+3500

Jalen Royals (Chiefs)

First TD

+10000

Anytime TD

+2200

Nikko Remigio (Chiefs)

First TD

+10000

Anytime TD

+2200

Derius Davis (Chargers)

First TD

+10000

Anytime TD

+3300

Receiving Yards

Rashee Rice (Chiefs)

Over 67.5

-112

Under 67.5

-112

Ladd McConkey (Chargers)

Over 43.5

-112

Under 43.5

-112

Travis Kelce (Chiefs)

Over 39.5

-112

Under 39.5

-112

Xavier Worthy (Chiefs)

Over 37.5

-112

Under 37.5

-112

Quentin Johnston (Chargers)

Over 33.5

-114

Under 33.5

-114

Oronde Gadsden II (Chargers)

Over 33.5

-112

Under 33.5

-112

Keenan Allen (Chargers)

Over 29.5

-114

Under 29.5

-114

Marquise Brown (Chiefs)

Over 15.5

-114

Under 15.5

-114

Tyquan Thornton (Chiefs)

Over 13.5

-112

Under 13.5

-112

JuJu Smith-Schuster (Chiefs)

Over 12.5

-112

Under 12.5

-112

Omarion Hampton (Chargers)

Over 11.5

-112

Under 11.5

-112

Noah Gray (Chiefs)

Over 11.5

-112

Under 11.5

-112

Tre Harris (Chargers)

Over 10.5

-114

Under 10.5

-114

Kareem Hunt (Chiefs)

Over 7.5

-112

Under 7.5

-112

Rushing Yards

Omarion Hampton (Chargers)

Over 42.5

-112

Under 42.5

-112

Kareem Hunt (Chiefs)

Over 36.5

-112

Under 36.5

-112

Isiah Pacheco (Chiefs)

Over 30.5

-112

Under 30.5

-112

Kimani Vidal (Chargers)

Over 29.5

-112

Under 29.5

-112

Justin Herbert (Chargers)

Over 22.5

-112

Under 22.5

-112

Patrick Mahomes (Chiefs)

Over 21.5

-112

Under 21.5

-112

Xavier Worthy (Chiefs)

Over 4.5

+116

Under 4.5

-147

Passing Yards

Patrick Mahomes (Chiefs)

Over 236.5

-112

Under 236.5

-112

Justin Herbert (Chargers)

Over 202.5

-112

Under 202.5

-112

It’s good to consider all wagering options when it comes to NFL and micro betting can be an exciting way to get involved in the action. When everything goes in-game, consider whether a player will make or miss a field goal.

Chiefs Hold Advantage in Recent Head-to-Head Meetings at GEHA Field at Arrowhead Stadium

The Chiefs have eight wins and two losses in the last 10 games at home, averaging 25.80 points on offense and surrendering 16.60 on defense.

The Chargers have six wins and four losses in the last 10 road games, scoring 22.00 points per matchup and conceding 20.30.

The Chiefs defeated the Chargers 19-17 when the teams last met at GEHA Field at Arrowhead Stadium. Over the last 6 head-to-head clashes at GEHA Field at Arrowhead Stadium, the Chiefs have secured four victories, as the Chargers have picked up two.

Last 10 Games		W-L	P	PF	PA	O41.5	U41.5
Chiefs Home Stats		7-3	40.90	24.90	16.00	4	6
Chargers Away Stats		4-6	39.70	17.50	22.20	4	6

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O41.5 = Games Over 41.5 Points
• U41.5 = Games Under 41.5 Points

Latest regular season and playoff games stats.

Los Angeles Chargers Stats

Kansas City Chiefs Stats

Moneyline

• 2 wins and 8 defeats in the last 10 games
• 4 wins and 6 defeats in the last 10 games on the road

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +7.5 Betting Line: Have covered the spread in 5 of the last 10 games
• +7.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road

Point Spread

• -7.5 Betting Line: Have covered the spread in 2 of the last 10 games
• -7.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games

Total Points

• Game Totals: An average of 37.00 pts in the previous 10 games
• Game Totals on the Road: An average of 39.70 pts in the previous 10 games on the road
• Over 41.5: Covered in 2 of the previous 10 games
• Over 41.5 on the Road: Covered in 4 of the previous 10 games on the road
• Team Totals: Have scored an average of 15.60 pts and allowed 21.40 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 17.50 pts and allowed 22.20 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 40.70 pts in the previous 10 games
• Game Totals at Home: An average of 40.90 pts in the previous 10 home games
• Over 41.5: Covered in 3 of the previous 10 games
• Over 41.5 at Home: Covered in 4 of the previous 10 home games
• Team Totals: Have scored an average of 20.30 pts and allowed 20.40 pts in the last 10 games
• Team Totals at Home: Have scored an average of 24.90 pts and allowed 16.00 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 291.00 Yds. Allowed 312.00 Yds
• Rushing Yards: Gained 116.10 Yds. Allowed 111.30 Yds
• Passing Yards: Gained 174.90 Yds. Allowed 200.70 Yds
• Total Touchdowns: Scored 1.60 TD. Allowed 2.10 TD
• Rushing Touchdowns: Scored 0.30 TD. Allowed 0.10 TD
• Passing Touchdowns: Scored 0.40 TD. Allowed 0.50 TD
• Total 1st Downs: Picked up 17.60. Allowed 17.90
• Total Turnovers: Committed 1.80. Committed by opponents 1.50
• Total Penalties: Committed 6.80. Committed by opponents 7.00
• Penalty Yards: Lost 53.60 Yds. Gained 64.50 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 296.30 Yds. Allowed 317.40 Yds
• Rushing Yards: Gained 116.00 Yds. Allowed 109.40 Yds
• Passing Yards: Gained 180.30 Yds. Allowed 208.00 Yds
• Total Touchdowns: Scored 2.10 TD. Allowed 1.80 TD
• Rushing Touchdowns: Scored 0.20 TD. Allowed 0.40 TD
• Passing Touchdowns: Scored 0.40 TD. Allowed 0.70 TD
• Total 1st Downs: Picked up 16.40. Allowed 19.10
• Total Turnovers: Committed 0.90. Committed by opponents 1.20
• Total Penalties: Committed 7.40. Committed by opponents 6.50
• Penalty Yards: Lost 57.20 Yds. Gained 48.40 Yds

Last 10 Games on the Road

• Total Yards: Gained 303.90 Yds. Allowed 297.80 Yds
• Rushing Yards: Gained 118.90 Yds. Allowed 129.40 Yds
• Passing Yards: Gained 185.00 Yds. Allowed 168.40 Yds
• Total Touchdowns: Scored 1.50 TD. Allowed 2.40 TD
• Rushing Touchdowns: Scored 0.40 TD. Allowed 0.80 TD
• Passing Touchdowns: Scored 0.80 TD. Allowed 0.60 TD
• Total 1st Downs: Picked up 17.80. Allowed 18.70
• Total Turnovers: Committed 1.40. Committed by opponents 1.50
• Total Penalties: Committed 7.00. Committed by opponents 6.10
• Penalty Yards: Lost 55.20 Yds. Gained 53.50 Yds

Last 10 Home Games

• Total Yards: Gained 366.40 Yds. Allowed 263.80 Yds
• Rushing Yards: Gained 130.70 Yds. Allowed 90.70 Yds
• Passing Yards: Gained 235.70 Yds. Allowed 173.10 Yds
• Total Touchdowns: Scored 2.70 TD. Allowed 1.60 TD
• Rushing Touchdowns: Scored 0.60 TD. Allowed 0.30 TD
• Passing Touchdowns: Scored 1.40 TD. Allowed 0.90 TD
• Total 1st Downs: Picked up 22.90. Allowed 15.00
• Total Turnovers: Committed 1.00. Committed by opponents 1.00
• Total Penalties: Committed 5.70. Committed by opponents 6.20
• Penalty Yards: Lost 47.00 Yds. Gained 51.80 Yds

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