Giants vs Rams Prediction, Picks & Odds | 21 Sep 2026

NFL Betting Preview: Giants vs Rams

The New York Giants go up against the Los Angeles Rams at SoFi Stadium, with kickoff scheduled for 20:15 on Monday, September 21.

The Rams and the Giants should be able to accumulate enough points for our pick to win. We’re predicting Over 47.5 and odds of -115 are available for this outcome.

New York Giants won their previous game, beating Dallas Cowboys at home. It was a 28-20 win at MetLife Stadium. The Giants moved the ball for 394 yards, including 229 passing and 165 rushing yards. They scored 4 touchdowns and picked up 29 first downs.

Los Angeles Rams lost their last game, being beaten to San Francisco 49ers 27-7 at Melbourne Cricket Ground. The Rams moved the ball for 290 yards, breaking down to 168 passing and 122 rushing yards. The offense scored one touchdown and managed 15 first downs.

Head-to-Head Statistics

The Rams won the last matchup between the pair. Enjoying a 26-25 triumph when facing the Giants at MetLife Stadium. In the previous 3 H2H meetings, the Rams have won every time.

Quarterbacks

Jaxson Dart

213.5 Passing Yards

Over -114

Under -114

Matthew Stafford

242.5 Passing Yards

Over -114

Under -114

Giants vs Rams Prediction & Picks

From our key match prediction to correct score pick, top player prop insights and a builder tailored for value — our Giants vs Rams betting tips covers it all.

Game Prediction

Let’s go for Over 47.5 when these NFL teams lock horns. We think the line is too generous and we’re expecting the final total to be higher at -115.

The NFL handicappers at Sportsgambler.com regularly track injury updates and pair that with current form. We also tap into a deep stats database to highlight the key numbers that help shape our predictions.

Key Giants vs Rams stats:

• The 47.5 line has been covered in 3 of the last 5 Giants games.
• The 47.5 line has been covered in 6 of the last 10 Giants games.
• The 47.5 line has been covered in the last 2 Giants games.
• The 47.5 line has been covered in 8 of the last 10 Rams games.
• The 47.5 line has been covered in 12 of the last 20 Rams games.
• The 47.5 line has been covered in the last 2 games between these teams.

Over 47.5 Probability

According to the latest betting odds, our pick has a 53.5% chance of winning. However, our cappers research has found that the actual probability is closer to 60%. It is therefore regarded as a value bet.

There are ways to boost the odds on an Over pick and some bettors go down the Bet Builder route. It’s effectively a same game parlay where you throw in other selections.

Give yourself a head start. Explore the latest free bet promotions and bonus offers in our comprehensive guide.

Our Game Prediction

Over 47.5 Points @ -115 Watch Live Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Sep 20, 02:25). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Matthew Stafford Over 242.5 Passing Yards -114

Matthew Stafford (Rams) is available at -114 to reach over 242.5 passing yards. With confidence, we can back him to cover the generous QB Passing Yards line, as all the signs point to him reaching the expected total.

Latest Matthew Stafford Player Prop Odds

Touchdown

Anytime

+1600

First

+7500

Passing Yards

Over 242.5

-114

Under 242.5

-114

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Isaiah Likely Over 43.5 Receiving Yards -114

You can back Isaiah Likely (Giants) at -114 to reach over 43.5 receiving yards. There’s an opportunity to place a Player Receiving Yards bet, with him capable of covering an appealing line.

Latest Isaiah Likely Player Prop Odds

Touchdown

Anytime

+280

First

+1900

Receiving Yards

Over 43.5

-114

Under 43.5

-114

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Giants 24 - 28 Rams

For a fun wager, consider backing the Rams to claim a 28-24 victory. Although it’s a speculative bet, we are expecting things to be close between the two teams.

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Giants vs Rams Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

For this game, the sportsbooks’ Moneyline betting odds mean Los Angeles Rams are -333 favorites to win and that means a 77% chance of landing a victory. New York Giants are trading at bigger odds than their opponents and they can be backed at +265.

The spread is currently 7.5, with the total points line at 47.5. A Total wager relates to the number of points that will be scored overall. If you’re going for Over 47.5, then the odds are -115.

You can find hundreds of team props and game lines for every National Football League matchup, with the top sportsbooks creating lots of different options. Check out the pre-game and in-game selections before placing your bets.

Moneyline

Giants

+265

Rams

-333

Point Spread

Giants +7.5

-122

Rams -7.5

-100

Total Points

Under 47.5

-105

Over 47.5

-115

Kyren Williams can be backed to score a TD at any stage at -196. There is the opportunity to back the market leader to grab the first touchdown at +370.

Touchdown

Kyren Williams (Rams)

First TD

+370

Anytime TD

-196

Davante Adams (Rams)

First TD

+650

Anytime TD

-105

Puka Nacua (Rams)

First TD

+700

Anytime TD

-105

Cam Skattebo (Giants)

First TD

+750

Anytime TD

+105

Blake Corum (Rams)

First TD

+1100

Anytime TD

+195

Malik Nabers (Giants)

First TD

+1300

Anytime TD

+185

Jaxson Dart (Giants)

First TD

+1500

Anytime TD

+230

Colby Parkinson (Rams)

First TD

+1600

Anytime TD

+280

Tyler Higbee (Rams)

First TD

+1600

Anytime TD

+280

Terrance Ferguson (Rams)

First TD

+1700

Anytime TD

+340

Jordan Whittington (Rams)

First TD

+1700

Anytime TD

+340

Isaiah Likely (Giants)

First TD

+1900

Anytime TD

+280

Najee Harris (Giants)

First TD

+2500

Anytime TD

+410

Devin Singletary (Giants)

First TD

+2500

Anytime TD

+410

Malachi Fields (Giants)

First TD

+2700

Anytime TD

+440

Konata Mumpfield (Rams)

First TD

+3300

Anytime TD

+650

Tutu Atwell (Rams)

First TD

+3300

Anytime TD

+650

Xavier Smith (Rams)

First TD

+4000

Anytime TD

+1000

CJ Daniels (Rams)

First TD

+4000

Anytime TD

+1000

Theo Johnson (Giants)

First TD

+4500

Anytime TD

+750

Darnell Mooney (Giants)

First TD

+4500

Anytime TD

+850

Max Klare (Rams)

First TD

+7000

Anytime TD

+1800

Matthew Stafford (Rams)

First TD

+7500

Anytime TD

+1600

Odell Beckham Jr. (Giants)

First TD

+8000

Anytime TD

+1600

Ronnie Rivers (Rams)

First TD

+10000

Anytime TD

+2700

Thomas Fidone (Giants)

First TD

+10000

Anytime TD

+2700

Chris Manhertz (Giants)

First TD

+10000

Anytime TD

+2700

Patrick Ricard (Giants)

First TD

+10000

Anytime TD

+3000

Receiving Yards

Puka Nacua (Rams)

Over 84.5

-114

Under 84.5

-114

Malik Nabers (Giants)

Over 65.5

-114

Under 65.5

-114

Davante Adams (Rams)

Over 53.5

-114

Under 53.5

-114

Isaiah Likely (Giants)

Over 43.5

-114

Under 43.5

-114

Malachi Fields (Giants)

Over 26.5

-114

Under 26.5

-114

Kyren Williams (Rams)

Over 12.5

-114

Under 12.5

-114

Cam Skattebo (Giants)

Over 11.5

-114

Under 11.5

-114

Odell Beckham Jr. (Giants)

Over 6.5

-102

Under 6.5

-128

Rushing Yards

Kyren Williams (Rams)

Over 61.5

-114

Under 61.5

-114

Cam Skattebo (Giants)

Over 48.5

-114

Under 48.5

-114

Blake Corum (Rams)

Over 45.5

-114

Under 45.5

-114

Jaxson Dart (Giants)

Over 31.5

-114

Under 31.5

-114

Passing Yards

Matthew Stafford (Rams)

Over 242.5

-114

Under 242.5

-114

Jaxson Dart (Giants)

Over 213.5

-114

Under 213.5

-114

Rams Racking Up the Home Wins

The Rams have chalked up five straight victories at SoFi Stadium. They have a 8-2 record in their last 10 home games, putting up 26.90 points on average and giving up 18.40.

The Giants own a 1-9 mark in their past 10 games away from home, averaging 21.80 points on offense and surrendering 27.90 on defense.

The Rams earned a 17-9 win over the Giants the last time they played at SoFi Stadium.

Last 10 Games		W-L	P	PF	PA	O47.5	U47.5
Rams Home Stats		8-2	45.30	26.90	18.40	4	6
Giants Away Stats		1-9	49.70	21.80	27.90	5	5

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O47.5 = Games Over 47.5 Points
• U47.5 = Games Under 47.5 Points

Latest regular season and playoff games stats.

New York Giants Stats

Los Angeles Rams Stats

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 1 win and 9 defeats in the last 10 games on the road

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 8 wins and 2 defeats in the last 10 home games

Point Spread

• +7.5 Betting Line: Have covered the spread in 7 of the last 10 games
• +7.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road

Point Spread

• -7.5 Betting Line: Have covered the spread in 2 of the last 10 games
• -7.5 Betting Line at Home: Have covered the spread in 4 of the last 10 home games

Total Points

• Game Totals: An average of 48.00 pts in the previous 10 games
• Game Totals on the Road: An average of 49.70 pts in the previous 10 games on the road
• Over 47.5: Covered in 6 of the previous 10 games
• Over 47.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 23.60 pts and allowed 24.40 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 21.80 pts and allowed 27.90 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 57.30 pts in the previous 10 games
• Game Totals at Home: An average of 44.60 pts in the previous 10 home games
• Over 47.5: Covered in 8 of the previous 10 games
• Over 47.5 at Home: Covered in 3 of the previous 10 home games
• Team Totals: Have scored an average of 30.00 pts and allowed 27.30 pts in the last 10 games
• Team Totals at Home: Have scored an average of 26.50 pts and allowed 18.10 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 346.10 Yds. Allowed 329.70 Yds
• Rushing Yards: Gained 141.60 Yds. Allowed 134.80 Yds
• Passing Yards: Gained 204.50 Yds. Allowed 194.90 Yds
• Total Touchdowns: Scored 2.80 TD. Allowed 2.80 TD
• Rushing Touchdowns: Scored 1.20 TD. Allowed 1.10 TD
• Passing Touchdowns: Scored 1.00 TD. Allowed 1.20 TD
• Total 1st Downs: Picked up 21.10. Allowed 20.00
• Total Turnovers: Committed 0.90. Committed by opponents 1.10
• Total Penalties: Committed 7.40. Committed by opponents 7.10
• Penalty Yards: Lost 62.90 Yds. Gained 60.00 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 428.70 Yds. Allowed 367.00 Yds
• Rushing Yards: Gained 140.50 Yds. Allowed 124.60 Yds
• Passing Yards: Gained 288.20 Yds. Allowed 242.40 Yds
• Total Touchdowns: Scored 3.60 TD. Allowed 3.30 TD
• Rushing Touchdowns: Scored 1.20 TD. Allowed 0.70 TD
• Passing Touchdowns: Scored 1.90 TD. Allowed 1.60 TD
• Total 1st Downs: Picked up 23.30. Allowed 20.00
• Total Turnovers: Committed 1.10. Committed by opponents 1.20
• Total Penalties: Committed 4.20. Committed by opponents 5.10
• Penalty Yards: Lost 31.30 Yds. Gained 39.40 Yds

Last 10 Games on the Road

• Total Yards: Gained 347.30 Yds. Allowed 389.00 Yds
• Rushing Yards: Gained 113.80 Yds. Allowed 150.20 Yds
• Passing Yards: Gained 233.50 Yds. Allowed 238.80 Yds
• Total Touchdowns: Scored 2.50 TD. Allowed 3.10 TD
• Rushing Touchdowns: Scored 1.00 TD. Allowed 1.10 TD
• Passing Touchdowns: Scored 1.40 TD. Allowed 1.80 TD
• Total 1st Downs: Picked up 19.30. Allowed 22.50
• Total Turnovers: Committed 1.10. Committed by opponents 0.40
• Total Penalties: Committed 7.80. Committed by opponents 6.90
• Penalty Yards: Lost 63.60 Yds. Gained 57.20 Yds

Last 10 Home Games

• Total Yards: Gained 373.00 Yds. Allowed 319.70 Yds
• Rushing Yards: Gained 112.60 Yds. Allowed 101.70 Yds
• Passing Yards: Gained 260.40 Yds. Allowed 218.00 Yds
• Total Touchdowns: Scored 3.30 TD. Allowed 1.70 TD
• Rushing Touchdowns: Scored 0.60 TD. Allowed 0.30 TD
• Passing Touchdowns: Scored 2.40 TD. Allowed 1.10 TD
• Total 1st Downs: Picked up 21.70. Allowed 19.30
• Total Turnovers: Committed 0.80. Committed by opponents 1.80
• Total Penalties: Committed 5.20. Committed by opponents 5.70
• Penalty Yards: Lost 43.20 Yds. Gained 41.30 Yds

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