49ers vs Seahawks Prediction, Picks & Odds | 11 Oct 2026

49ers vs Seahawks Predictions

Best Bet

Seahawks -3 @ -118

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Place a wager on the Seahawks with a -3 spread when they face the Niners. This is an attractive number and we’re confident they can cover the line at -118.

Our expert Niners vs Seahawks betting coverage includes our Best Bet, Player Props, Same Game Parlay and Correct Score Prediction. Read the full analysis behind each pick further down the page.

49ers vs Seahawks Preview

The San Francisco 49ers go up against the Seattle Seahawks at Lumen Field, with kickoff scheduled for 16:25 on Sunday, October 11.

San Francisco 49ers made it four consecutive wins after a 24-14 home success over Denver Broncos at Levi's Stadium. The 49ers recorded 358 yards, with 218 through the air and 140 on the ground. The offense managed 20 first downs and found the end zone 3 times.

Seattle Seahawks last game was a 30-23 victory over Los Angeles Chargers at Lumen Field. That means it’s now been two home wins on the spin. The Seahawks moved the ball for 286 yards, split between 148 passing and 138 rushing yards. The offense picked up 19 first downs and crossed the goal line 4 times.

H2H: 7 Niners Wins in Previous 10 H2H Encounters

The Hawks have beaten the Niners in the last two matchups. A 13-3 victory at Levi's Stadium was followed by a 41-6 win at Lumen Field. It’s been seven Niners wins in the past 10 games between these teams.

Quarterbacks

Brock Purdy

228.5 Passing Yards

Over -114

Under -114

Sam Darnold

231.5 Passing Yards

Over -114

Under -114

Best Bet

The Seahawks are capable of covering the -3 line. We’re confident of a strong showing in this NFL showdown and a wager against the spread is the best play at -118.

Key stats supporting our main match prediction:

• The -3 line has been covered by Seahawks in 4 consecutive games at home.
• The -3 line has been covered by Seahawks in 8 of their last 10 games.
• The -3 line has been covered by Seahawks in 15 of their last 20 games.
• The -3 line has been covered by Seahawks in 2 consecutive games against 49ers.

Knowing which players are injured gives us a valuable edge when making NFL picks. After reviewing the form guide, we turn to the latest stats to shape our predictions.

Hawks -3 Probability

If you go by the best betting sites, our pick has a 54.1% chance of winning. Our analysts think there’s a stronger chance of success and calculate the probability to be closer to 60%. The bet can be recommended for this precise reason.

If you want bigger odds, then you can move the line by selling points. Choose how many points to sell until you are happy with the juice available.

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Seahawks -3 @ -118 Watch Live Bet Now

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Player Prop Picks

Top Pick: Brock Purdy Under 228.5 Passing Yards -114

Brock Purdy (Niners) is available at -114 to have less than 228.5 passing yards. He’s not guaranteed to cover the QB Passing Yards line and we’re happy to take this bet.

Latest Brock Purdy Player Prop Odds

Touchdown

Anytime

+550

First

+2700

Passing Yards

Over 228.5

-114

Under 228.5

-114

Rushing Yards

Over 23.5

-114

Under 23.5

-114

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George Kittle Under 54.5 Receiving Yards -114

George Kittle (Niners) is priced at -114 to have less than 54.5 receiving yards. There’s no reason to doubt our instinct, so we’ll bet on him falling short of the Player Receiving Yards line.

Latest George Kittle Player Prop Odds

Touchdown

Anytime

+170

First

+1100

Receiving Yards

Over 54.5

-114

Under 54.5

-114

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

49ers 14 - 24 Seahawks

There's a speculative wager that can be enjoyed on the Hawks when it comes to the correct score lines. Taking them to triumph 24-14 should provide some entertainment.

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49ers vs Seahawks Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The sportsbooks’ betting odds have Seattle Seahawks as -175 favorites for this game, implying that they are 64% likely to win. San Francisco 49ers are regarded as a long shot to win and you can currently back them at +146.

The spread is currently 3, with the total points line at 46.5. There is no denying the popularity of betting on the Totals. There’s the chance to back Under 46.5 at -115.

Take a well-rounded approach when placing your bets. The top NFL betting sites are packed with team props and game lines, so focus on finding the selection that reflects your read on the matchup.

Moneyline

49ers

+146

Seahawks

-175

Point Spread

49ers +3

-104

Seahawks -3

-118

Total Points

Under 46.5

-115

Over 46.5

-105

The First Touchdown Scorer favorite is Christian McCaffrey at +500. Similar odds can be found if you’re interested in this player to register the final TD.

Touchdown

Christian McCaffrey (49ers)

First TD

+500

Anytime TD

-154

Emanuel Wilson (Seahawks)

First TD

+550

Anytime TD

-135

Jaxon Smith-Njigba (Seahawks)

First TD

+600

Anytime TD

-120

George Kittle (49ers)

First TD

+1100

Anytime TD

+170

George Holani (Seahawks)

First TD

+1200

Anytime TD

+230

Mike Evans (49ers)

First TD

+1300

Anytime TD

+185

Deebo Samuel (49ers)

First TD

+1300

Anytime TD

+210

AJ Barner (Seahawks)

First TD

+1500

Anytime TD

+270

Rashid Shaheed (Seahawks)

First TD

+1600

Anytime TD

+330

Cooper Kupp (Seahawks)

First TD

+1800

Anytime TD

+340

Brock Purdy (49ers)

First TD

+2700

Anytime TD

+550

Kaelon Black (49ers)

First TD

+3000

Anytime TD

+700

Sam Darnold (Seahawks)

First TD

+3000

Anytime TD

+750

Receiving Yards

Jaxon Smith-Njigba (Seahawks)

Over 94.5

-114

Under 94.5

-114

George Kittle (49ers)

Over 54.5

-114

Under 54.5

-114

Mike Evans (49ers)

Over 50.5

-114

Under 50.5

-114

Christian McCaffrey (49ers)

Over 35.5

-114

Under 35.5

-114

Deebo Samuel (49ers)

Over 34.5

-114

Under 34.5

-114

Cooper Kupp (Seahawks)

Over 23.5

-114

Under 23.5

-114

AJ Barner (Seahawks)

Over 21.5

-114

Under 21.5

-114

Rashid Shaheed (Seahawks)

Over 20.5

-114

Under 20.5

-114

Tory Horton (Seahawks)

Over 11.5

-114

Under 11.5

-114

Emanuel Wilson (Seahawks)

Over 11.5

-114

Under 11.5

-114

George Holani (Seahawks)

Over 9.5

-114

Under 9.5

-114

Rushing Yards

Emanuel Wilson (Seahawks)

Over 62.5

-114

Under 62.5

-114

Christian McCaffrey (49ers)

Over 49.5

-114

Under 49.5

-114

Brock Purdy (49ers)

Over 23.5

-114

Under 23.5

-114

George Holani (Seahawks)

Over 19.5

-114

Under 19.5

-114

Kaelon Black (49ers)

Over 16.5

-114

Under 16.5

-114

Deebo Samuel (49ers)

Over 8.5

-114

Under 8.5

-114

Sam Darnold (Seahawks)

Over 4.5

-120

Under 4.5

-108

Passing Yards

Sam Darnold (Seahawks)

Over 231.5

-114

Under 231.5

-114

Brock Purdy (49ers)

Over 228.5

-114

Under 228.5

-114

Can Hawks Make It Another Home Victory?

The Seahawks have reeled off nine in a row at Lumen Field. They own a 9-1 mark in their past 10 home games, putting up 30.30 points per contest and giving up 19.80.

The Niners have gone 7-3 across their last 10 games games on the road, scoring 26.50 points per contest and conceding 22.70.

The Hawks defeated the Niners 41-6 the last time they played at Lumen Field. Over the past 8 head-to-head meetings at Lumen Field, the Niners have collected five wins, while the Hawks have three.

Last 10 Games		W-L	P	PF	PA	O46.5	U46.5
Seahawks Home Stats		9-1	50.10	30.30	19.80	6	4
49ers Away Stats		7-3	49.20	26.50	22.70	6	4

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O46.5 = Games Over 46.5 Points
• U46.5 = Games Under 46.5 Points

Latest regular season and playoff games stats.

San Francisco 49ers Stats

Seattle Seahawks Stats

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 games on the road

Moneyline

• 9 wins and 1 defeat in the last 10 games
• 9 wins and 1 defeat in the last 10 home games

Point Spread

• +3 Betting Line: Have covered the spread in 8 of the last 10 games
• +3 Betting Line on the Road: Have covered the spread in 7 of the last 10 games on the road

Point Spread

• -3 Betting Line: Have covered the spread in 8 of the last 10 games
• -3 Betting Line at Home: Have covered the spread in 7 of the last 10 home games

Total Points

• Game Totals: An average of 50.70 pts in the previous 10 games
• Game Totals on the Road: An average of 49.20 pts in the previous 10 games on the road
• Over 46.5: Covered in 6 of the previous 10 games
• Over 46.5 on the Road: Covered in 6 of the previous 10 games on the road
• Team Totals: Have scored an average of 28.10 pts and allowed 22.60 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 26.50 pts and allowed 22.70 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 45.30 pts in the previous 10 games
• Game Totals at Home: An average of 50.10 pts in the previous 10 home games
• Over 46.5: Covered in 5 of the previous 10 games
• Over 46.5 at Home: Covered in 6 of the previous 10 home games
• Team Totals: Have scored an average of 28.40 pts and allowed 16.90 pts in the last 10 games
• Team Totals at Home: Have scored an average of 30.30 pts and allowed 19.80 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 369.20 Yds. Allowed 324.20 Yds
• Rushing Yards: Gained 126.80 Yds. Allowed 119.80 Yds
• Passing Yards: Gained 242.40 Yds. Allowed 204.40 Yds
• Total Touchdowns: Scored 3.50 TD. Allowed 2.50 TD
• Rushing Touchdowns: Scored 0.40 TD. Allowed 0.90 TD
• Passing Touchdowns: Scored 1.40 TD. Allowed 0.80 TD
• Total 1st Downs: Picked up 22.10. Allowed 19.50
• Total Turnovers: Committed 1.10. Committed by opponents 0.50
• Total Penalties: Committed 3.70. Committed by opponents 6.20
• Penalty Yards: Lost 37.60 Yds. Gained 44.20 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 346.50 Yds. Allowed 292.60 Yds
• Rushing Yards: Gained 134.60 Yds. Allowed 98.50 Yds
• Passing Yards: Gained 211.90 Yds. Allowed 194.10 Yds
• Total Touchdowns: Scored 3.30 TD. Allowed 1.80 TD
• Rushing Touchdowns: Scored 0.80 TD. Allowed 0.20 TD
• Passing Touchdowns: Scored 0.50 TD. Allowed 0.30 TD
• Total 1st Downs: Picked up 21.00. Allowed 17.00
• Total Turnovers: Committed 1.00. Committed by opponents 1.80
• Total Penalties: Committed 6.10. Committed by opponents 6.20
• Penalty Yards: Lost 51.20 Yds. Gained 48.10 Yds

Last 10 Games on the Road

• Total Yards: Gained 331.60 Yds. Allowed 351.00 Yds
• Rushing Yards: Gained 103.00 Yds. Allowed 112.50 Yds
• Passing Yards: Gained 228.60 Yds. Allowed 238.50 Yds
• Total Touchdowns: Scored 2.90 TD. Allowed 2.70 TD
• Rushing Touchdowns: Scored 0.70 TD. Allowed 0.90 TD
• Passing Touchdowns: Scored 1.80 TD. Allowed 1.60 TD
• Total 1st Downs: Picked up 20.90. Allowed 19.90
• Total Turnovers: Committed 1.10. Committed by opponents 1.20
• Total Penalties: Committed 3.90. Committed by opponents 6.30
• Penalty Yards: Lost 30.70 Yds. Gained 44.10 Yds

Last 10 Home Games

• Total Yards: Gained 334.70 Yds. Allowed 326.60 Yds
• Rushing Yards: Gained 126.90 Yds. Allowed 100.60 Yds
• Passing Yards: Gained 207.80 Yds. Allowed 226.00 Yds
• Total Touchdowns: Scored 3.40 TD. Allowed 2.00 TD
• Rushing Touchdowns: Scored 1.10 TD. Allowed 0.40 TD
• Passing Touchdowns: Scored 1.00 TD. Allowed 0.90 TD
• Total 1st Downs: Picked up 19.70. Allowed 19.50
• Total Turnovers: Committed 1.50. Committed by opponents 2.00
• Total Penalties: Committed 6.80. Committed by opponents 7.00
• Penalty Yards: Lost 57.10 Yds. Gained 57.30 Yds

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