DePaul vs Creighton Prediction, Picks & Odds | 25 Feb 2026
College Basketball Betting Preview: DePaul vs Creighton
The DePaul Blue Demons face the Creighton Bluejays, with tip-off scheduled for 21:00 on Wednesday, February 25.
We think a wager on the totals provides value after finding that the line is set at a generous 141.5. Expect DePaul and Creighton to surpass this number at -115.
DePaul Blue Demons were defeated in their previous game. They were beaten at home to Providence Friars by a 71-68 scoreline.
Creighton Bluejays suffered a defeat in their last game. A 81-52 scoreline occurred on the road against St. John's Red Storm.
Head-to-Head Statistics
The scoreline was 72-71 in favor of DePaul when they last played Creighton. In the past 10 games between the teams, Creighton have won nine.
| NCAAB | Overall | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|
DePaul
|
16-16 | 2248 | 2226 | 22 | 12-9 | 4-7 | 3L |
Creighton
|
15-17 | 2404 | 2401 | 3 | 11-6 | 4-11 | 1L |
DePaul vs Creighton Prediction & Picks
Get the edge with our best DePaul vs Creighton tips: a key match prediction, correct score recommendation, top player prop bets and a ready-made bet builder.
Game Prediction
We’re forecasting that the two teams will produce a significant combined points total in this college game. Therefore, our pick is to take the -115 that there are Over 141.5 points.
We track all injuries that could impact each team before making our basketball picks. The form guide and latest stats also help the Sportsgambler.com team crunch the numbers ahead of the college hoops action.
Key DePaul vs Creighton stats:
Over 141.5 Probability
When you look at the latest odds, our pick has a 53.5% chance of landing a return. However, our analysts research has found that the actual probability is closer to 60%. That means we’re regarding it as a value bet.
If you’re wanting bigger odds when wagering on the Totals, then the good news is that you can be in control of the line. Get more juice by betting Over a certain number.
Explore the best betting offers before you stake your money. Our guide showcases a variety of welcome bonuses worth grabbing.
Player Prop Picks
Nik Graves (Creighton) can be backed to register Over 4.5 assists at -154. With some confidence, we can shoot for him to cover the generous Player Assists total.
Latest Nik Graves Player Prop Odds
Josh Dix (Creighton) is available at -135 to have Under 4.5 rebounds. Let’s shoot for a relatively low total and take him to go under the Player Rebounds line.
Latest Josh Dix Player Prop Odds
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Picks
Get in the game with a same game parlay. Our picks are Over 142.5 on the total, DePaul to cover the +3.5 spread and Nik Graves (Creighton) to get Over 4.5 assists.
We recommend a same game parlay as it’s a fantastic way of wagering on a single event. Many basketball bettors like to create a personalised wager which reflects their predictions for how a game is going to play out.
Correct Score Prediction
72
-
75
Creighton
We’ll roll the dice and go for the Bluejays to register a 75-72 victory. We don’t think that there will be too much between the teams and we’re happy to take the massive odds.
DePaul vs Creighton Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
With a 67% chance of securing victory, Creighton are favorites for this college game and the sportsbooks have them at betting odds of -204. For those wanting to oppose the market leader, you can get +168 about DePaul.
The spread is calculated to be 4.5, while total points comes in at 142.5. A Total bet is always available and can often provide value selections. If you’re going for Over 142.5, then the odds are -110.
Whether you’re betting pre-game or in-game, the top basketball sportsbooks serve up a wide range of team props and game lines to choose from. The options are nearly endless, and it’s great to have so much variety.
NJ Benson is the favorite to hit the most buckets. You can get -115 that he scores Over 15.5 points or -110 that he goes Under.
Among the various options for wagering on college basketball, you will find that micro betting is provided. It focuses on short-term in-game outcomes such as Next Field Goal, where you select if the shot will be a two or three-pointer.
- NCAAB: 12/02 2026 Creighton 71 DePaul 72
- NCAAB: 14/03 2025 DePaul 81 Creighton 85
- NCAAB: 27/02 2025 DePaul 65 Creighton 75
- NCAAB: 22/01 2025 Creighton 73 DePaul 49
- NCAAB: 28/01 2024 DePaul 62 Creighton 85
- NCAAB: 10/01 2024 Creighton 84 DePaul 58
- NCAAB: 05/03 2023 Creighton 84 DePaul 70
- NCAAB: 25/12 2022 DePaul 65 Creighton 80
- NCAAB: 18/02 2022 Creighton 71 DePaul 59
- NCAAB: 22/01 2022 DePaul 47 Creighton 60
Latest regular season and playoff games stats.
DePaul Stats
Creighton Stats
- 4 wins and 6 defeats in the last 10 games
- 2 wins and 8 defeats in the last 10 games on the road
- +5.5 Betting Line: Have covered the spread in 6 of the last 10 games
- +5.5 Betting Line on the Road: Have covered the spread in 4 of the last 10 games on the road
- -5.5 Betting Line: Have covered the spread in 1 of the last 10 games
- -5.5 Betting Line at Home: Have covered the spread in 2 of the last 10 home games
- Game Totals: An average of 140.80 pts in the previous 10 games
- Game Totals on the Road: An average of 139.70 pts in the previous 10 games on the road
- Over 141.5: Covered in 4 of the previous 10 games
- Over 141.5 on the Road: Covered in 4 of the previous 10 games on the road
- Team Totals: Have scored an average of 69.10 pts and allowed 71.70 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 66.20 pts and allowed 73.50 pts in the last 10 games on the road
- Game Totals: An average of 154.00 pts in the previous 10 games
- Game Totals at Home: An average of 158.90 pts in the previous 10 home games
- Over 141.5: Covered in 8 of the previous 10 games
- Over 141.5 at Home: Covered in 9 of the previous 10 home games
- Team Totals: Have scored an average of 72.20 pts and allowed 81.80 pts in the last 10 games
- Team Totals at Home: Have scored an average of 79.00 pts and allowed 79.90 pts in the last 10 home games
NCAAB Table Select Season
| Big East | Overall | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|
UConn
|
29-5 | 2635 | 2214 | 421 | 18-2 | 11-3 | 1L |
St. John's
|
28-6 | 2773 | 2379 | 394 | 18-3 | 10-3 | 6W |
Villanova
|
24-8 | 2469 | 2265 | 204 | 15-4 | 9-4 | 1L |
Seton Hall
|
21-12 | 2321 | 2156 | 165 | 13-5 | 8-7 | 1L |
|
DePaul
|
16-16 | 2248 | 2226 | 22 | 12-9 | 4-7 | 3L |
Butler
|
16-16 | 2540 | 2481 | 59 | 13-8 | 3-8 | 1L |
Georgetown
|
16-18 | 2503 | 2479 | 24 | 10-8 | 6-10 | 1L |
|
Creighton
|
15-17 | 2404 | 2401 | 3 | 11-6 | 4-11 | 1L |
Providence
|
15-18 | 2815 | 2772 | 43 | 10-7 | 5-11 | 1L |
Xavier
|
15-18 | 2586 | 2661 | -75 | 13-7 | 2-11 | 1L |
Marquette
|
12-20 | 2405 | 2425 | -20 | 10-9 | 2-11 | 1L |
- Overall = Overall Wins-Losses
- PF = Total Points For
- PA = Total Points Against
- N. Pts = Point Differential
- Home = Home Record
- Away = Away Record
- Strk = Current Streak
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