Michigan State vs Duke Prediction, Picks & Odds | 10 Nov 2026

Michigan State vs Duke Predictions

Best Bet

Duke -6.5 @ -102

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Get with Duke with a -6.5 spread. We’re backing the favorites at -102 to enjoy a solid win when they go head to head with Michigan State.

We highlight the top Michigan State vs Duke predictions with our Best Bet, Same Game Parlay and Correct Score Pick. Scroll down for a detailed breakdown of each play.

Michigan State vs Duke Preview

The Michigan State Spartans go up against the Duke Blue Devils, with tip-off scheduled for 19:00 on Tuesday, November 10.

Michigan State Spartans won their previous game, beating Toledo Rockets at home. It was a 91-61 win.

Duke Blue Devils were winners last time out. It was a 113-52 home victory against Coastal Carolina Chanticleers.

H2H: Duke 66-60 Winners in Most Recent H2H

Duke triumphed 66-60 when they last played Michigan State. Duke have racked up three straight wins over Michigan State. On the head-to-head front, they have won 4 of the past 6.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	2-0	197	102	95	2-0	0-0	2W
Michigan State	2-0	187	120	67	2-0	0-0	2W

View Full Standings

Best Bet

The best betting angle could be Duke against the spread. You can land -102 that the market leaders are able to cover the -6.5 line and they are more than capable in this college contest.

Key stats supporting our main match prediction:

• The -6.5 line has been covered by Duke in 13 of their last 20 games.
• The -6.5 line has been covered by Duke in 3 of their last 5 games.
• The -6.5 line has been covered by Duke in 2 consecutive games.

Sportsgambler.com brings strong college hoops expertise, built on knowing the team news as soon as it’s confirmed. Recent form plays a big part in our basketball picks and we always back it up with the most relevant stats.

Duke -6.5 Probability

If you go by the top sportsbooks, our pick has a 50.5% chance of winning. However, our analysts think that the probability is close to 60% taking all factors into consideration. It’s why we think it’s worth placing this college basketball wager.

A Bet Builder provides you with the chance to combine Duke against the spread with other picks. For every additional selection, the odds are boosted.

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Duke -6.5 @ -102 Bet Now

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Correct Score Prediction

Michigan State 72 - 83 Duke

Should you want to go for a selection at massive odds, head to the correct score lines where the Blue Devils can be backed speculatively to achieve a 83-72 victory.

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Michigan State vs Duke Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The sportsbooks’ betting odds have Duke as -263 favorites for this college game, implying that they are 72% likely to win. Michigan State are the underdogs at +210 and they’re regarded as least likely to win.

6.5 is the spread and 148.5 is the total points line. There are many ways to bet on basketball including the Totals. There’s an opportunity to bet Over 148.5 at -110.

If you’re planning to place a bet on a college hoops matchup, visit the top basketball betting sites and check out the many available game lines and team props. Find the lines which are the most attractive.

Moneyline

MSU

+210

Duke

-263

Point Spread

MSU +6.5

-120

Duke -6.5

-102

Total Points

Under 148.5

-110

Over 148.5

-110

Latest regular season and playoff games stats.

Michigan State Stats

Duke Stats

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 games on the road

Moneyline

• 9 wins and 1 defeat in the last 10 games
• 9 wins and 1 defeat in the last 10 home games

Point Spread

• +6.5 Betting Line: Have covered the spread in 9 of the last 10 games
• +6.5 Betting Line on the Road: Have covered the spread in 8 of the last 10 games on the road

Point Spread

• -6.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -6.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games

Total Points

• Game Totals: An average of 155.30 pts in the previous 10 games
• Game Totals on the Road: An average of 144.70 pts in the previous 10 games on the road
• Over 148.5: Covered in 7 of the previous 10 games
• Over 148.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 82.70 pts and allowed 72.60 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 73.20 pts and allowed 71.50 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 144.80 pts in the previous 10 games
• Game Totals at Home: An average of 144.80 pts in the previous 10 home games
• Over 148.5: Covered in 3 of the previous 10 games
• Over 148.5 at Home: Covered in 3 of the previous 10 home games
• Team Totals: Have scored an average of 80.40 pts and allowed 64.40 pts in the last 10 games
• Team Totals at Home: Have scored an average of 80.40 pts and allowed 64.40 pts in the last 10 home games

NCAAB Table Select Season 2026/20272025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Virginia	3-0	277	204	73	3-0	0-0	3W
Pittsburgh	3-0	257	194	63	3-0	0-0	3W
Notre Dame	3-0	251	198	53	2-0	1-0	3W
Clemson	3-0	259	222	37	3-0	0-0	3W
Duke	2-0	197	102	95	2-0	0-0	2W
Florida State	2-0	203	137	66	2-0	0-0	2W
Louisville	2-0	191	127	64	2-0	0-0	2W
Virginia Tech	2-0	184	121	63	2-0	0-0	2W
North Carolina	2-0	189	142	47	2-0	0-0	2W
Boston College	2-0	147	105	42	2-0	0-0	2W
SMU	2-0	180	142	38	2-0	0-0	2W
NC State	2-0	160	127	33	2-0	0-0	2W
Georgia Tech	2-0	170	138	32	2-0	0-0	2W
Syracuse	2-1	256	190	66	2-0	0-1	1L
Miami	2-1	239	185	54	2-0	0-1	2W
California	2-1	267	242	25	2-1	0-0	1L
Wake Forest	1-1	134	136	-2	1-0	0-1	1L

Big Ten	Overall	PF	PA	N. Pts	Home	Away	Strk
Indiana	3-0	266	206	60	3-0	0-0	3W
Northwestern	3-0	236	180	56	3-0	0-0	3W
Minnesota	3-0	224	173	51	2-0	1-0	3W
Illinois	2-0	232	115	117	2-0	0-0	2W
Michigan State	2-0	187	120	67	2-0	0-0	2W
Iowa	2-0	167	101	66	2-0	0-0	2W
UCLA	2-0	198	138	60	1-0	1-0	2W
Nebraska	2-0	173	122	51	2-0	0-0	2W
Oregon	2-0	185	140	45	2-0	0-0	2W
USC	2-0	188	149	39	1-0	1-0	2W
Washington	2-0	167	140	27	2-0	0-0	2W
Wisconsin	2-0	148	132	16	2-0	0-0	2W
Rutgers	1-0	81	54	27	1-0	0-0	1W
Penn State	2-1	269	232	37	2-0	0-1	1L
Ohio State	2-1	256	233	23	2-0	0-1	2W
Maryland	1-1	170	153	17	1-0	0-1	1L
Michigan	1-1	161	153	8	1-1	0-0	1L
Purdue	1-2	228	220	8	1-2	0-0	1W

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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