Niagara vs Duke Prediction, Picks & Odds | 21 Nov 2025
College Basketball Betting Preview: Niagara vs Duke
The Niagara Purple Eagles square off against the Duke Blue Devils, with tip-off scheduled for 19:00 on Friday, November 21.
Let's take a chance on the underdogs and wager Niagara with a +39.5 points start. They should be able to cover the line against Duke at odds of -110.
Niagara Purple Eagles were defeated in their previous game. On the road, they suffered a 74-68 reverse against Le Moyne Dolphins.
Duke Blue Devils won their last game, beating Kansas Jayhawks at home. It was a 78-66 win.
| NCAAB | Overall | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|
Duke
|
32-2 | 2798 | 2147 | 651 | 21-0 | 11-2 | 11W |
Niagara
|
8-22 | 1916 | 2137 | -221 | 6-7 | 2-15 | 1L |
Niagara vs Duke Prediction & Picks
We’ve lined up expert Niagara vs Duke betting tips, from our match prediction and correct score call to player prop picks and best bet builder advice. Read on for the full breakdown.
Game Prediction
The best bet could be Niagara at -110 on the spread. They have been given a +39.5 points start and should be able to stay relatively close to the big favorites in this college matchup.
The college hoops handicappers at Sportsgambler.com regularly track injury updates and pair that with current form. We also tap into a deep stats database to highlight the key numbers that help shape our basketball picks.
Key Niagara vs Duke stats:
Niagara +39.5 Probability
The top sportsbooks make it a 52.4% chance that our pick is settled as a winner. However, our cappers research has found that the actual probability is between 55-60%. That means we’re regarding it as a value bet.
If you’re searching for bigger odds when it comes to Niagara covering the line, then consider a Bet Builder. This allows you to load additional selections to your wager.
Get more from your bets with our detailed guide, featuring the best free bets and generous welcome bonuses.
Player Prop Picks
Cameron Boozer (Duke) can be backed to have Over 10.5 rebounds at -110. Out of all the prop bets, we’re going Over when it comes to this Player Rebounds wager.
Latest Cameron Boozer Player Prop Odds
Isaiah Evans (Duke) is available at -120 to record Under 14.5 points. There could well be a failure on his part to cover the total and this looks pretty generous to us.
Latest Isaiah Evans Player Prop Odds
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Picks
We’ve compiled a same game parlay that includes Niagara +39.5 on the spread, along with Under 147.5 and Cameron Boozer (Duke) to get Over 10.5 rebounds.
The same game parlay option allows you to combine different outcomes within the same game. You need all your picks to be correct although bettors love to place a tailored basketball bet on the matchup which interests them most.
Correct Score Prediction
Niagara vs Duke Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
The Moneyline betting odds might not be available with some sportsbooks as there’s a big underdog in the form of Niagara. However, the Spread can provide some great alternative wagering options.
39.5 is the spread and 146.5 is the total points line. There is no denying the popularity of betting on the Totals. Those who wager Under 146.5 can get -105.
Whether you are betting pre-game or in-game, you can feast on a wide range of team props and game lines at the top basketball sportsbooks. The selections are practically endless, and it’s fantastic to have so many options.
Cameron Boozer is the favorite to land the most baskets. You can back -115 that he gets Over 21.5 points. Alternatively, Under is trading at the same odds.
Instead of focusing on the overall outcome, some bettors prefer to look at the college basketball micro betting lines. As the name suggests, it means placing short-term in-game wagers and this might include Next Field Goal, with the options being for a two-pointer or a three-pointer.
Latest regular season and playoff games stats.
Niagara Stats
Duke Stats
- 3 wins and 7 defeats in the last 10 games
- 4 wins and 6 defeats in the last 10 games on the road
- +39.5 Betting Line: Have covered the spread in the last 10 games
- +39.5 Betting Line on the Road: Have covered the spread in the last 10 games on the road
- -39.5 Betting Line: Have covered the spread in 3 of the last 10 games
- -39.5 Betting Line at Home: Have covered the spread in 2 of the last 10 home games
- Game Totals: An average of 140.00 pts in the previous 10 games
- Game Totals on the Road: An average of 139.30 pts in the previous 10 games on the road
- Over 146.5: Covered in 3 of the previous 10 games
- Over 146.5 on the Road: Covered in 3 of the previous 10 games on the road
- Team Totals: Have scored an average of 67.40 pts and allowed 72.60 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 67.20 pts and allowed 72.10 pts in the last 10 games on the road
- Game Totals: An average of 154.00 pts in the previous 10 games
- Game Totals at Home: An average of 150.20 pts in the previous 10 home games
- Over 146.5: Covered in 6 of the previous 10 games
- Over 146.5 at Home: Covered in 5 of the previous 10 home games
- Team Totals: Have scored an average of 89.60 pts and allowed 64.40 pts in the last 10 games
- Team Totals at Home: Have scored an average of 85.50 pts and allowed 64.70 pts in the last 10 home games
NCAAB Table Select Season
| Atlantic Coast | Overall | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|
Duke
|
32-2 | 2798 | 2147 | 651 | 21-0 | 11-2 | 11W |
Virginia
|
29-5 | 2742 | 2326 | 416 | 19-1 | 10-4 | 1L |
Miami
|
25-8 | 2704 | 2349 | 355 | 16-4 | 9-4 | 1L |
North Carolina
|
24-8 | 2553 | 2282 | 271 | 19-1 | 5-7 | 2L |
Clemson
|
24-10 | 2521 | 2269 | 252 | 16-3 | 8-7 | 1L |
Louisville
|
23-10 | 2797 | 2382 | 415 | 16-2 | 7-8 | 1L |
California
|
21-11 | 2492 | 2344 | 148 | 17-4 | 4-7 | 2L |
Stanford
|
20-12 | 2431 | 2326 | 105 | 12-7 | 8-5 | 1L |
NC State
|
20-13 | 2762 | 2525 | 237 | 13-7 | 7-6 | 1L |
SMU
|
20-13 | 2779 | 2561 | 218 | 17-3 | 3-10 | 1L |
Virginia Tech
|
19-13 | 2521 | 2396 | 125 | 15-4 | 4-9 | 2L |
Florida State
|
18-15 | 2652 | 2572 | 80 | 12-8 | 6-7 | 1L |
Wake Forest
|
17-16 | 2602 | 2543 | 59 | 12-6 | 5-10 | 1L |
Syracuse
|
15-17 | 2400 | 2376 | 24 | 12-6 | 3-11 | 6L |
Notre Dame
|
13-18 | 2308 | 2335 | -27 | 11-7 | 2-11 | 2L |
Pittsburgh
|
13-20 | 2327 | 2370 | -43 | 8-10 | 5-10 | 1L |
Boston College
|
11-20 | 2090 | 2191 | -101 | 10-10 | 1-10 | 1W |
Georgia Tech
|
11-20 | 2287 | 2400 | -113 | 10-10 | 1-10 | 12L |
| Metro Atlantic Athletic | Overall | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|
Merrimack
|
23-11 | 2330 | 2260 | 70 | 13-2 | 10-9 | 1L |
Siena
|
23-11 | 2398 | 2233 | 165 | 11-4 | 12-7 | 4W |
Fairfield
|
21-13 | 2528 | 2432 | 96 | 13-4 | 8-9 | 1L |
Marist
|
19-12 | 2160 | 1979 | 181 | 11-4 | 8-8 | 1L |
Quinnipiac
|
19-13 | 2411 | 2303 | 108 | 10-6 | 9-7 | 1L |
Saint Peter's
|
17-12 | 2054 | 1984 | 70 | 13-2 | 4-10 | 1L |
Iona
|
18-14 | 2363 | 2340 | 23 | 11-5 | 7-9 | 1L |
Mount St. Mary's
|
15-17 | 2178 | 2244 | -66 | 8-5 | 7-12 | 1L |
Sacred Heart
|
14-19 | 2482 | 2528 | -46 | 8-5 | 6-14 | 1L |
Manhattan
|
12-20 | 2369 | 2526 | -157 | 8-7 | 4-13 | 4L |
Canisius
|
10-21 | 1951 | 2184 | -233 | 7-8 | 3-13 | 1L |
Niagara
|
8-22 | 1916 | 2137 | -221 | 6-7 | 2-15 | 1L |
Rider
|
4-25 | 1840 | 2204 | -364 | 4-9 | 0-16 | 2L |
- Overall = Overall Wins-Losses
- PF = Total Points For
- PA = Total Points Against
- N. Pts = Point Differential
- Home = Home Record
- Away = Away Record
- Strk = Current Streak
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