Ohio State vs Michigan State Prediction, Picks & Odds | 22 Feb 2026

College Basketball Betting Preview: Ohio State vs Michigan State

The Ohio State Buckeyes battle the Michigan State Spartans, with tip-off scheduled for 13:00 on Sunday, February 22.

Ohio State and Michigan State should be able to accumulate enough points for our prediction to win. We’re forecasting Over 144.5 and odds of -115 are available for this outcome.

Ohio State Buckeyes previous game saw them claim a 86-69 home win over Wisconsin Badgers.

Michigan State Spartans last game saw them claim a 82-59 home win over UCLA Bruins.

Head-to-Head Statistics

Michigan State beat Ohio State in their last head-to-head matchup. It was a 69-62 scoreline. We’ve seen six Michigan State wins in the past 10 meetings between the teams.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Michigan State	25-7	2526	2189	337	17-3	8-4	2L
Ohio State	21-12	2633	2402	231	15-5	6-7	1L

View Full Standings

Ohio State vs Michigan State Prediction & Picks

Get the edge with our best Ohio State vs Michigan State picks: a key match prediction, correct score recommendation and a ready-made bet builder. Explore each section below for detailed insights.

Game Prediction

These teams are capable of scoring more than 144.5 points in this college matchup. Therefore, we’re going Over the total line and expect a payout at -115.

The college hoops handicappers at Sportsgambler.com regularly track injury updates and pair that with current form. We also tap into a deep stats database to highlight the key numbers that help shape our basketball picks.

Key Ohio State vs Michigan State stats:

• The 144.5 line has been covered in 6 of the last 10 Ohio State games.
• The 144.5 line has been covered in 12 of the last 20 Ohio State games.
• The 144.5 line has been covered in 4 of the last 5 MSU games.

Over 144.5 Probability

The top betting apps imply that our pick has a 53.5% prospect of delivering a return. However, we think that the probability is close to 60% taking all factors into consideration. This is why we can recommend this college basketball wager.

There are ways to get bigger odds by betting Over on the Totals. Bettors often look to move the line so they can land a more profitable return if the selection wins.

Thinking of betting? Browse our detailed guide for the best current offers, including free bets and the latest bonuses.

Our Game Prediction

Over 144.5 Points @ -115 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Feb 21, 21:03). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Ohio State 67 - 81 Michigan State

There are a range of correct score lines to choose from and we’re taking a chance on the Spartans to record a 81-67 victory. There’s a huge return if we get this right.

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Ohio State vs Michigan State Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The sportsbooks are taking no chances with their Moneyline odds of -588 about Michigan State which reflects they have a 85% chance of winning this college game. Ohio State are trading at bigger odds than their opponents and they can be backed at +420.

The current spread is 9.5 and total points is 146.5. Basketball fans regularly enjoy the opportunity to bet on the Totals. If you're keen on Over 146.5, this selection is available at -105.

The best betting sites offer stacks of team props and game lines when it comes to most college basketball contests. Make sure you look through all the available options before deciding which bet to place.

Moneyline

Ohio State

+420

MSU

-588

Point Spread

Ohio State +9.5

-105

MSU -9.5

-115

Total Points

Under 146.5

-115

Over 146.5

-105

As an alternative to the game lines, check out the player prop bets that are available. It’s especially great if you have a view when it comes to Turnovers, Steals, Blocks and Points, while there are lots of other options.

An increasing number of bettors are now enjoying micro betting on college basketball and it’s something which is available on an in-game basis. Wait for the action to start and then wager on something specific to happen.

Latest regular season and playoff games stats.

Ohio State Stats

Michigan State Stats

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 9 wins and 1 defeat in the last 10 home games

Point Spread

• +10.5 Betting Line: Have covered the spread in 8 of the last 10 games
• +10.5 Betting Line on the Road: Have covered the spread in 9 of the last 10 games on the road

Point Spread

• -10.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -10.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games

Total Points

• Game Totals: An average of 153.70 pts in the previous 10 games
• Game Totals on the Road: An average of 150.00 pts in the previous 10 games on the road
• Over 144.5: Covered in 6 of the previous 10 games
• Over 144.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 78.00 pts and allowed 75.70 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 75.30 pts and allowed 74.70 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 148.40 pts in the previous 10 games
• Game Totals at Home: An average of 153.60 pts in the previous 10 home games
• Over 144.5: Covered in 5 of the previous 10 games
• Over 144.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 79.00 pts and allowed 69.40 pts in the last 10 games
• Team Totals at Home: Have scored an average of 85.10 pts and allowed 68.50 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big Ten	Overall	PF	PA	N. Pts	Home	Away	Strk
Michigan	31-3	2952	2353	599	19-2	12-1	1L
Nebraska	26-6	2473	2119	354	19-3	7-3	1L
Michigan State	25-7	2526	2189	337	17-3	8-4	2L
Purdue	27-8	2858	2455	403	16-5	11-3	4W
Illinois	24-8	2700	2234	466	15-6	9-2	1L
Wisconsin	24-10	2822	2581	241	16-2	8-8	1L
UCLA	23-11	2643	2414	229	18-3	5-8	1L
Ohio State	21-12	2633	2402	231	15-5	6-7	1L
Iowa	21-12	2482	2177	305	17-3	4-9	1L
Indiana	18-14	2501	2309	192	15-6	3-8	2L
USC	18-14	2515	2494	21	11-7	7-7	8L
Washington	16-17	2545	2430	115	11-6	5-11	1L
Minnesota	15-17	2241	2193	48	13-8	2-9	1L
Northwestern	15-19	2487	2447	40	11-9	4-10	1L
Rutgers	14-19	2329	2479	-150	11-7	3-12	1L
Oregon	12-20	2267	2366	-99	10-10	2-10	1L
Penn State	12-20	2358	2539	-181	10-10	2-10	3L
Maryland	12-21	2300	2527	-227	9-8	3-13	1L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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