TCU vs Duke Prediction, Picks & Odds | 21 Mar 2026

College Basketball Betting Preview: TCU vs Duke

No. 9 TCU Horned Frogs battle No. 1 Duke Blue Devils in this NCAA Tournament Second Round matchup at Bon Secours Wellness Arena in Greenville, South Carolina, with tip-off scheduled for 16:15 on Saturday, March 21.

We think a wager on the totals provides value after finding that the line is set at a generous 139.5. Expect TCU and Duke to surpass this number at -115.

The TCU Horned Frogs (23-11, 6th in Big 12) secured a 66-64 win over the Ohio State Buckeyes in a tight First Round matchup.

The Duke Blue Devils (33-2, 1st in ACC), ranked No. 1 in the AP Top 25, beat the Siena Saints 71-65 in the First Round.

NCAAB Regular Season	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	0-0	0	0	0	0-0	0-0	-
TCU	0-0	0	0	0	0-0	0-0	-

View Full Standings

TCU vs Duke Prediction & Picks

Make the most of TCU vs Duke with our betting analysis that includes an expert match prediction, expected scoreline, key player prop picks and a value-focused bet builder.

Game Prediction

The teams are capable of exceeding the set points total line which leads us to predict Over 139.5 as a great pick at -115 for this college matchup.

Our expert college basketball handicappers study recent form and take injuries into account when assessing each matchup. Before delivering a verdict, we combine that insight with the latest stats to strengthen our analysis.

Key TCU vs Duke stats:

• The 139.5 line has been covered in 8 of the last 10 TCU games on the road.
• The 139.5 line has been covered in 14 of the last 20 TCU games.
• The 139.5 line has been covered in 11 of the last 20 Duke games at home.

Over 139.5 Probability

When you look at the latest odds, our pick has a 53.5% chance of landing a return. In the opinion of our analysts, there’s actually a probability of success closer to 60%. That means we’re regarding it as a value bet.

Secure more desirable odds by moving the line when you place an Over wager. You can choose from a range of options on the Totals until you’re happy with your bet.

Maximize your first bet with the latest betting promotions. Our guide covers all the top welcome bonuses out there.

Our Game Prediction

Over 139.5 Points @ -115 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Mar 20, 21:02). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Micah Robinson Over 11.5 Points -105

Micah Robinson (TCU) can be backed to register Over 11.5 points at -105. We think that the line looks really appealing for this Player Points bet as we’re expecting him to cover this total.

Latest Micah Robinson Player Prop Odds

Points

Over 10.5

-114

Under 10.5

-114

Rebounds

Over 4.5

-123

Under 4.5

-104

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Xavier Edmonds Under 6.5 Rebounds +108

Xavier Edmonds (TCU) can be backed to record Under 6.5 rebounds at +108. We really like this player prop so we’re going to bet on him to fall short when it comes to rebounds.

Latest Xavier Edmonds Player Prop Odds

Points

Over 11.5

-114

Under 11.5

-114

Rebounds

Over 6.5

-135

Under 6.5

+105

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

TCU 66 - 81 Duke

For those wanting a big return from a small stake, consider the correct score lines. For example, Duke can be backed to win 81-66 at huge betting odds.

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TCU vs Duke Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The sportsbooks are taking no chances with their Moneyline odds of -833 about Duke which reflects they have a 89% chance of winning this college game. TCU are the underdogs at +570 and they’re regarded as least likely to win.

The spread is 11.5 and the total points line is currently 139.5. The Totals offers basketball fans an alternative way of getting involved. The Over 139.5 selection is available to back at -115.

If you’re planning to place a bet on a college basketball contest, visit the best sportsbooks and check out the wide range of team props and game lines. Find the lines which are the most attractive.

Moneyline

TCU

+570

Duke

-833

Point Spread

TCU +11.5

-110

Duke -11.5

-110

Total Points

Under 139.5

-105

Over 139.5

-115

The favorite to score most points is Cameron Boozer. You can get -112 that he scores Over 23.5 points or -115 that he goes Under.

Cameron Boozer (Duke)

Over 23.5

-112

Under 23.5

-115

Isaiah Evans (Duke)

Over 15.5

-116

Under 15.5

-111

David Punch (TCU)

Over 13.5

-118

Under 13.5

-110

Cayden Boozer (Duke)

Over 12.5

-114

Under 12.5

-114

Xavier Edmonds (TCU)

Over 11.5

-114

Under 11.5

-114

Micah Robinson (TCU)

Over 10.5

-114

Under 10.5

-114

Jayden Pierre (TCU)

Over 9.5

-114

Under 9.5

-114

Dame Sarr (Duke)

Over 7.5

-152

Under 7.5

+117

Cameron Boozer (Duke)

Over 5.5

+128

Under 5.5

-167

Cameron Boozer (Duke)

Over 10.5

-141

Under 10.5

+108

David Punch (TCU)

Over 6.5

-154

Under 6.5

+118

Xavier Edmonds (TCU)

Over 6.5

-135

Under 6.5

+105

Micah Robinson (TCU)

Over 4.5

-123

Under 4.5

-104

Micro betting provides a rollercoaster ride for college basketball bettors. It can be great to enjoy the live lines, with the opportunity to bet on the Next Field Goal. Watch the live action before deciding which way to go.

Latest regular season and playoff games stats.

TCU Stats

Duke Stats

Moneyline

• 8 wins and 2 defeats in the last 10 games

Moneyline

• 10 wins and 0 defeats in the last 10 games

Point Spread

• +11.5 Betting Line: Have covered the spread in the last 10 games

Point Spread

• -11.5 Betting Line: Have covered the spread in 6 of the last 10 games

Total Points

• Game Totals: An average of 150.50 pts in the previous 10 games
• Over 139.5: Covered in 6 of the previous 10 games
• Team Totals: Have scored an average of 77.30 pts and allowed 73.20 pts in the last 10 games

Total Points

• Game Totals: An average of 144.70 pts in the previous 10 games
• Over 139.5: Covered in 5 of the previous 10 games
• Team Totals: Have scored an average of 81.30 pts and allowed 63.40 pts in the last 10 games

NCAAB Regular Season Table Select Season 2026/20272025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Notre Dame	1-0	74	72	2	0-0	1-0	1W
Boston College	0-0	0	0	0	0-0	0-0	-
California	0-0	0	0	0	0-0	0-0	-
Clemson	0-0	0	0	0	0-0	0-0	-
Duke	0-0	0	0	0	0-0	0-0	-
Florida State	0-0	0	0	0	0-0	0-0	-
Georgia Tech	0-0	0	0	0	0-0	0-0	-
Louisville	0-0	0	0	0	0-0	0-0	-
Miami	0-0	0	0	0	0-0	0-0	-
NC State	0-0	0	0	0	0-0	0-0	-
North Carolina	0-0	0	0	0	0-0	0-0	-
Pittsburgh	0-0	0	0	0	0-0	0-0	-
SMU	0-0	0	0	0	0-0	0-0	-
Syracuse	0-0	0	0	0	0-0	0-0	-
Virginia	0-0	0	0	0	0-0	0-0	-
Virginia Tech	0-0	0	0	0	0-0	0-0	-
Wake Forest	0-0	0	0	0	0-0	0-0	-

Big 12	Overall	PF	PA	N. Pts	Home	Away	Strk
Arizona State	0-0	0	0	0	0-0	0-0	-
Arizona	0-0	0	0	0	0-0	0-0	-
Baylor	0-0	0	0	0	0-0	0-0	-
BYU	0-0	0	0	0	0-0	0-0	-
Cincinnati	0-0	0	0	0	0-0	0-0	-
Colorado	0-0	0	0	0	0-0	0-0	-
Houston	0-0	0	0	0	0-0	0-0	-
Iowa State	0-0	0	0	0	0-0	0-0	-
Kansas	0-0	0	0	0	0-0	0-0	-
Kansas State	0-0	0	0	0	0-0	0-0	-
Oklahoma State	0-0	0	0	0	0-0	0-0	-
TCU	0-0	0	0	0	0-0	0-0	-
Texas Tech	0-0	0	0	0	0-0	0-0	-
UCF	0-0	0	0	0	0-0	0-0	-
Utah	0-0	0	0	0	0-0	0-0	-
West Virginia	0-0	0	0	0	0-0	0-0	-

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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