Vanderbilt vs Nebraska Prediction, Picks & Odds | 21 Mar 2026

College Basketball Betting Preview: Vanderbilt vs Nebraska

No. 5 Vanderbilt Commodores face No. 4 Nebraska Cornhuskers in this NCAA Tournament Second Round matchup at Paycom Center in Oklahoma City, with tip-off scheduled for 19:45 on Saturday, March 21.

We’re keeping our betting prediction nice and simple by heading to the Moneyline. Take the more than generous +106 that Nebraska are able to secure a victory over Vanderbilt.

The Vanderbilt Commodores (27-8, 4th in SEC) progressed to the Second Round with a 78-68 win over the McNeese State Cowboys.

The Nebraska Cornhuskers (27-6, 2nd in Big Ten) cruised to a 76-47 win over the Troy Trojans in the First Round.

NCAAB Regular Season	Overall	PF	PA	N. Pts	Home	Away	Strk
Nebraska	0-0	0	0	0	0-0	0-0	-
Vanderbilt	0-0	0	0	0	0-0	0-0	-

View Full Standings

Vanderbilt vs Nebraska Prediction & Picks

This Vanderbilt vs Nebraska betting breakdown features a main match prediction, a correct score insight and a sharply constructed bet builder to guide your wagers.

Game Prediction

For this Second Round matchup, our pick is Nebraska to win against inferior opposition and we think that the +106 represents an attractive wager on the Moneyline.

The formbook is always a smart starting point when making basketball predictions. Up-to-date college hoops team news is just as important, while the stats we provide often reveal valuable insights.

Key Vanderbilt vs Nebraska stats:

• Nebraska have won 17 of their last 20 games at home.
• Nebraska have won 4 of their last 5 games at home.

Nebraska Moneyline Probability

The top betting apps imply that our pick has a 48.5% prospect of delivering a return. In the opinion of our cappers, there’s actually a probability of success between 55-60%. This college basketball wager can therefore be backed with confidence.

If you’re looking for a bet at bigger odds, then Nebraska on the Double Result lines could be a good way forward. You need the Huskers to lead at the halfway stage and then claim a win.

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Our Game Prediction

Nebraska Moneyline @ +106 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Mar 21, 00:02). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Vanderbilt 73 - 78 Nebraska

Should you wish to go for a speculative bet, try the Huskers to win 78-73 on the correct score lines. This should be a fun wager which could potentially yield a huge return.

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Vanderbilt vs Nebraska Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

There are betting odds of +108 that Nebraska land victory, with Vanderbilt alternatively at -130. If you want to know the probability of the road team winning this NCAA Tournament game, it’s 56% according to the most popular sportsbooks.

The current spread is 1.5 and total points is 146.5. The Totals offers basketball fans an alternative way of getting involved. If you're keen on Over 146.5, this selection is available at -115.

There are plenty of team props and game lines when it comes to wagering on college matchups and we recommend visiting the best basketball sportsbooks to find the wager that matches your view on the game.

Moneyline

Vanderbilt

-130

Nebraska

+108

Point Spread

Vanderbilt -1.5

-120

Nebraska +1.5

-102

Total Points

Under 146.5

-105

Over 146.5

-115

As an alternative to the game lines and team props, check out the player props that are available. These can be a great alternative if you want to focus on a player’s performance. The best gambling sites will provide lots of options.

Micro betting is something that’s really popular with bettors, with college basketball fans essentially being able to wager in-game when it comes to score, player and team props. Check out the two-way lines where you can bet whether the next shot will be a Two-pointer or a Three-pointer.

Latest regular season and playoff games stats.

Vanderbilt Stats

Nebraska Stats

Moneyline

• 6 wins and 4 defeats in the last 10 games

Moneyline

• 6 wins and 4 defeats in the last 10 games

Point Spread

• -1.5 Betting Line: Have covered the spread in 6 of the last 10 games

Point Spread

• +1.5 Betting Line: Have covered the spread in 6 of the last 10 games

Total Points

• Game Totals: An average of 158.90 pts in the previous 10 games
• Over 146.5: Covered in 7 of the previous 10 games
• Team Totals: Have scored an average of 80.40 pts and allowed 78.50 pts in the last 10 games

Total Points

• Game Totals: An average of 135.60 pts in the previous 10 games
• Over 146.5: Covered in 4 of the previous 10 games
• Team Totals: Have scored an average of 71.00 pts and allowed 64.60 pts in the last 10 games

NCAAB Regular Season Table Select Season 2026/20272025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big Ten	Overall	PF	PA	N. Pts	Home	Away	Strk
Illinois	0-0	0	0	0	0-0	0-0	-
Indiana	0-0	0	0	0	0-0	0-0	-
Iowa	0-0	0	0	0	0-0	0-0	-
Maryland	0-0	0	0	0	0-0	0-0	-
Michigan State	0-0	0	0	0	0-0	0-0	-
Michigan	0-0	0	0	0	0-0	0-0	-
Minnesota	0-0	0	0	0	0-0	0-0	-
Nebraska	0-0	0	0	0	0-0	0-0	-
Northwestern	0-0	0	0	0	0-0	0-0	-
Ohio State	0-0	0	0	0	0-0	0-0	-
Oregon	0-0	0	0	0	0-0	0-0	-
Penn State	0-0	0	0	0	0-0	0-0	-
Purdue	0-0	0	0	0	0-0	0-0	-
Rutgers	0-0	0	0	0	0-0	0-0	-
USC	0-0	0	0	0	0-0	0-0	-
UCLA	0-0	0	0	0	0-0	0-0	-
Washington	0-0	0	0	0	0-0	0-0	-
Wisconsin	0-0	0	0	0	0-0	0-0	-

Southeastern	Overall	PF	PA	N. Pts	Home	Away	Strk
Alabama	0-0	0	0	0	0-0	0-0	-
Arkansas	0-0	0	0	0	0-0	0-0	-
Auburn	0-0	0	0	0	0-0	0-0	-
Florida	0-0	0	0	0	0-0	0-0	-
Georgia	0-0	0	0	0	0-0	0-0	-
Kentucky	0-0	0	0	0	0-0	0-0	-
LSU	0-0	0	0	0	0-0	0-0	-
Ole Miss	0-0	0	0	0	0-0	0-0	-
Mississippi State	0-0	0	0	0	0-0	0-0	-
Missouri	0-0	0	0	0	0-0	0-0	-
Oklahoma	0-0	0	0	0	0-0	0-0	-
South Carolina	0-0	0	0	0	0-0	0-0	-
Tennessee	0-0	0	0	0	0-0	0-0	-
Texas A&M	0-0	0	0	0	0-0	0-0	-
Texas	0-0	0	0	0	0-0	0-0	-
Vanderbilt	0-0	0	0	0	0-0	0-0	-

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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