Vanderbilt vs Nebraska Prediction, Picks & Odds | 21 Mar 2026

College Basketball Betting Preview: Vanderbilt vs Nebraska

No. 5 Vanderbilt Commodores face No. 4 Nebraska Cornhuskers in this NCAA Tournament Second Round matchup at Paycom Center in Oklahoma City, with tip-off scheduled for 19:45 on Saturday, March 21.

We’re keeping our betting prediction nice and simple by heading to the Moneyline. Take the more than generous +106 that Nebraska are able to secure a victory over Vanderbilt.

The Vanderbilt Commodores (27-8, 4th in SEC) progressed to the Second Round with a 78-68 win over the McNeese State Cowboys.

The Nebraska Cornhuskers (27-6, 2nd in Big Ten) cruised to a 76-47 win over the Troy Trojans in the First Round.

NCAAB Regular Season	Overall	PF	PA	N. Pts	Home	Away	Strk
Nebraska	26-6	2473	2119	354	19-3	7-3	1L
Vanderbilt	26-8	2936	2557	379	15-3	11-5	1L

View Full Standings

Vanderbilt vs Nebraska Prediction & Picks

This Vanderbilt vs Nebraska betting breakdown features a main match prediction, a correct score insight and a sharply constructed bet builder to guide your wagers.

Game Prediction

For this Second Round matchup, our pick is Nebraska to win against inferior opposition and we think that the +106 represents an attractive wager on the Moneyline.

The formbook is always a smart starting point when making basketball predictions. Up-to-date college hoops team news is just as important, while the stats we provide often reveal valuable insights.

Key Vanderbilt vs Nebraska stats:

• Nebraska have won 17 of their last 20 games at home.
• Nebraska have won 4 of their last 5 games at home.

Nebraska Moneyline Probability

The top betting apps imply that our pick has a 48.5% prospect of delivering a return. In the opinion of our cappers, there’s actually a probability of success between 55-60%. This college basketball wager can therefore be backed with confidence.

If you’re looking for a bet at bigger odds, then Nebraska on the Double Result lines could be a good way forward. You need the Huskers to lead at the halfway stage and then claim a win.

Getting ready to bet? Don’t miss out on the latest betting offers! Check out our in-depth guide packed with the best welcome bonuses just for you.

Our Game Prediction

Nebraska Moneyline @ +106 Bet Now

BetMGM Promo Up To $1500 in Bonus Bets Get Bonus T&C apply. Gamble responsibly 18+

Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Mar 21, 00:02). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Vanderbilt 73 - 78 Nebraska

Should you wish to go for a speculative bet, try the Huskers to win 78-73 on the correct score lines. This should be a fun wager which could potentially yield a huge return.

T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Vanderbilt vs Nebraska Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

There are betting odds of +108 that Nebraska land victory, with Vanderbilt alternatively at -130. If you want to know the probability of the road team winning this NCAA Tournament game, it’s 56% according to the most popular sportsbooks.

The current spread is 1.5 and total points is 146.5. The Totals offers basketball fans an alternative way of getting involved. If you're keen on Over 146.5, this selection is available at -115.

There are plenty of team props and game lines when it comes to wagering on college matchups and we recommend visiting the best basketball sportsbooks to find the wager that matches your view on the game.

Moneyline

Vanderbilt

-130

Nebraska

+108

Point Spread

Vanderbilt -1.5

-120

Nebraska +1.5

-102

Total Points

Under 146.5

-105

Over 146.5

-115

As an alternative to the game lines and team props, check out the player props that are available. These can be a great alternative if you want to focus on a player’s performance. The best gambling sites will provide lots of options.

Micro betting is something that’s really popular with bettors, with college basketball fans essentially being able to wager in-game when it comes to score, player and team props. Check out the two-way lines where you can bet whether the next shot will be a Two-pointer or a Three-pointer.

Latest regular season and playoff games stats.

Vanderbilt Stats

Nebraska Stats

Moneyline

• 6 wins and 4 defeats in the last 10 games

Moneyline

• 6 wins and 4 defeats in the last 10 games

Point Spread

• -1.5 Betting Line: Have covered the spread in 6 of the last 10 games

Point Spread

• +1.5 Betting Line: Have covered the spread in 6 of the last 10 games

Total Points

• Game Totals: An average of 158.90 pts in the previous 10 games
• Over 146.5: Covered in 7 of the previous 10 games
• Team Totals: Have scored an average of 80.40 pts and allowed 78.50 pts in the last 10 games

Total Points

• Game Totals: An average of 135.60 pts in the previous 10 games
• Over 146.5: Covered in 4 of the previous 10 games
• Team Totals: Have scored an average of 71.00 pts and allowed 64.60 pts in the last 10 games

NCAAB Regular Season Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big Ten	Overall	PF	PA	N. Pts	Home	Away	Strk
Michigan	31-3	2952	2353	599	19-2	12-1	1L
Nebraska	26-6	2473	2119	354	19-3	7-3	1L
Michigan State	25-7	2526	2189	337	17-3	8-4	2L
Purdue	27-8	2858	2455	403	16-5	11-3	4W
Illinois	24-8	2700	2234	466	15-6	9-2	1L
Wisconsin	24-10	2822	2581	241	16-2	8-8	1L
UCLA	23-11	2643	2414	229	18-3	5-8	1L
Ohio State	21-12	2633	2402	231	15-5	6-7	1L
Iowa	21-12	2482	2177	305	17-3	4-9	1L
Indiana	18-14	2501	2309	192	15-6	3-8	2L
USC	18-14	2515	2494	21	11-7	7-7	8L
Washington	16-17	2545	2430	115	11-6	5-11	1L
Minnesota	15-17	2241	2193	48	13-8	2-9	1L
Northwestern	15-19	2487	2447	40	11-9	4-10	1L
Rutgers	14-19	2329	2479	-150	11-7	3-12	1L
Oregon	12-20	2267	2366	-99	10-10	2-10	1L
Penn State	12-20	2358	2539	-181	10-10	2-10	3L
Maryland	12-21	2300	2527	-227	9-8	3-13	1L

Southeastern	Overall	PF	PA	N. Pts	Home	Away	Strk
Florida	26-7	2864	2376	488	18-3	8-4	1L
Arkansas	26-8	3058	2723	335	20-3	6-5	5W
Vanderbilt	26-8	2936	2557	379	15-3	11-5	1L
Alabama	23-9	2935	2671	264	15-6	8-3	1L
Georgia	22-10	2874	2533	341	15-6	7-4	1L
Tennessee	22-11	2622	2289	333	16-5	6-6	1L
Texas A&M	21-11	2807	2546	261	14-5	7-6	1L
Missouri	20-12	2549	2411	138	15-4	5-8	3L
Kentucky	21-13	2746	2510	236	16-6	5-7	1L
Texas	18-14	2681	2458	223	13-7	5-7	3L
Oklahoma	19-15	2813	2621	192	13-5	6-10	1L
Auburn	17-16	2730	2620	110	14-6	3-10	1L
LSU	15-17	2606	2512	94	10-9	5-8	4L
Ole Miss	15-20	2656	2664	-8	9-9	6-11	1L
Mississippi State	13-19	2484	2618	-134	9-10	4-9	6L
South Carolina	13-19	2398	2447	-49	11-8	2-11	1L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

Top Basketball Pages