Columbus Crew vs LA Galaxy Prediction, Betting Tips, Lineups & Odds | 22 Apr 2026

MLS Betting Preview: Columbus Crew vs LA Galaxy

Columbus Crew take on LA Galaxy at Lower.com Field, with kick-off set for 19:30 on Wednesday 22 April.

Columbus are priced at -152 to secure a Full-Time Result victory and we think these odds are too big. We’re expecting the hosts to land a win against LA Galaxy and a nice potential return is on the cards.

Columbus Crew were beaten in their last game. Away from home at Gillette Stadium, New England Revolution claimed a 2-1 win. Henrik Rydstroem's side had 51% possession and managed four shots on target, while Max Arfsten was the goalscorer.

LA Galaxy had a 2-2 draw at Toyota Stadium in their previous game. This was away to Dallas. Los Galácticos recorded 53% possession and managed four shots on goal, with Lucas Sanabria and Joseph Paintsil both on target.

Head-to-Head Statistics

The scoreline was 2-0 in favour of home side Columbus when they last played Galaxy, with the clash taking place at Lower.com Field.

MLS		G	W	D	L	GF	GA	GD	GD	P
19	LA Galaxy	8	2	3	3	12	13	-1	12:13	9
25	Columbus Crew	8	1	3	4	10	12	-2	10:12	6

View Full Table

Columbus have 2 wins, 5 losses and 3 draws, averaging 1.5 goals from 5.2 shots on goal and 11.0 attempts. The Crew have averaged 55.6% possession and 6.9 corners per match, with the opposition scoring 1.4 goals from 3.6 shots on goal, 7.5 attempts and 4.4 corners.

Top goalscorer is Wessam Abou Ali on 5 goals, while Max Arfsten and Diego Rossi have both bagged 3. Leading assistor is Max Arfsten with 3.

Galaxy have 4 victories, 3 defeats and 3 draws, averaging 12.7 attempts, 6.3 shots on goal and 1.6 goals. The Los Angeles outfit average 54.3% possession, 6.5 corners awarded and 3.1 corners against them, while 1.5 goals have been conceded from 3.5 shots on goal and 8.7 attempts.

Joao Klauss has top scored with 5, while Lucas Sanabria, Joseph Paintsil and Marco Reus are next on 2. Gabriel Pec has been the chief assist maker in the previous 10 games with 4.

Predicted & Confirmed Lineups

Columbus Crew predicted lineup (4-4-2): Patrick Schulte (GK), Steven Moreira, Rudy Camacho, Sean Zawadzki, Malte Amundsen, Hugo Picard, Dylan Chambost, Andre Gomes, Max Arfsten, Dániel Gazdag, Diego Rossi.

LA Galaxy predicted lineup (4-3-3): JT Marcinkowski (GK), John Nelson, Justin Haak, Maya Yoshida, Carlos Garcés, Mauricio Cuevas, Edwin Cerrillo, Lucas Sanabria, Gabriel Pec, João Klauss, Joseph Paintsil.

Columbus Crew vs LA Galaxy Prediction & Betting Tips

Our Columbus Crew vs LA Galaxy betting outlook has it all, including a trusted match forecast, our predicted score, best corners advice, top player prop picks and a hand-picked bet builder.

Match Prediction

There’s every chance that Columbus can win this MLS clash and we’ll happily back the home team to land the glory. Grab the odds of -152 with confidence that a victory can be landed.

Injuries and suspensions are studied by the team at Sportsgambler.com. Our football predictions also come from studying the latest MLS form, with the numbers playing a huge part before the tips are decided.

Key Columbus Crew vs LA Galaxy league stats:

• Galaxy have lost 10 of their last 18 games on the road.

The betting odds at the top bookies suggest our pick carries a 60.2% chance of winning. After careful examination, our experts have this probability close to 70%. It’s why we think it’s worth placing this wager.

As an alternative, you could consider the Asian Handicap where you can back Columbus to cover a particular line. That means you might need a margin of victory to yield a return.

Make your bet go further. Browse our updated guide packed with the best free bets, sign-up offers and betting bonuses.

Our Match Prediction

Columbus To Win @ -152 Watch Live Bet Now

BetMGM Promo Up To $1500 in Bonus Bets Get Bonus T&C apply. Gamble responsibly 18+

Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Apr 21, 01:58). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Columbus 2 - 0 Galaxy

Columbus can be backed at +700 to triumph by a 2-0 scoreline. It can be fun to have a wager on the correct score and there’s a big potential return if the bet wins.

Player Prop Picks

Top Pick: Max Arfsten to Score +300

Max Arfsten (Columbus) has racked up two goals in his past five MLS matches. There are odds of +300 available for this Anytime Goalscorer wager and we think this is a value proposition for the player to find the net.

Latest Max Arfsten Player Prop Odds

Goalscorer

Anytime

+300

First

+900

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Corners Prediction

Galaxy Over 3.5 Corners -159

It’s been an average of 7.40 LA Galaxy corners in the past five games, with Columbus conceding a corner average of 4.40 in their previous ten matches. The Galaxy Team Corners line looks attractive and we’re going to take the -159 that it’s covered.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

Columbus

Total

11.30 6.90 4.40

Home

7.90 5.80 2.10

Away

11.50 5.60 5.90

Galaxy

Total

9.60 6.50 3.10

Home

10.70 6.60 4.10

Away

10.80 5.40 5.40

Latest Corner Odds

Total Corners

Over 10.5

-128

Under 10.5

-111

Columbus Corners

Over 6.5

-103

Under 6.5

-139

Galaxy Corners

Over 3.5

-164

Under 3.5

+115

Most Corners

1

-233

X

+750

2

+215

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Columbus Crew vs LA Galaxy Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

With an approximate 60% chance of succeeding, the bookies are being cautious with their -149 betting odds for Columbus Crew triumphing in this MLS encounter. For those wanting to back LA Galaxy, you will find +360 about this outsider.

A 2+ goal margin of victory for Columbus against Galaxy means a full payout at -118 when backing them on the Asian Handicap -0.75. A one-goal win means half the stake wins and half is refunded.

Over 2.5 Goals is the market leader and that means three or more goals are predicted. The Both Teams to Score market is always popular and BTTS Yes can be backed at -200.

Bettors love the flexibility that hundreds of markets provide and that is for every MLS game. The best football betting sites ensure that their customers always have plenty of options.

Full-Time Result

1

-149

X

+300

2

+360

Half-Time Result

1

+115

X

+150

2

+330

Double Chance

1X

-526

12

-435

X2

+114

Draw No Bet

1

-357

2

+225

Asian Handicap

1 Hcp -0.75

-118

2 Hcp +0.75

-108

Total Goals

Under 2.5

+150

Over 2.5

-200

Both Teams to Score

Yes

-200

No

+140

Those interested in Diego Rossi to find the net anytime are able to get +120. There is the chance to back the favourite to score the first goal at odds of +380.

Diego Rossi (Columbus)

First

+120

Anytime

+380

Nariman Akhundzade (Columbus)

First

+170

Anytime

+500

Jamal Thiaré (Columbus)

First

+230

Anytime

+650

Gabriel Pec (Galaxy)

First

+230

Anytime

+750

João Klauss De Mello (Galaxy)

First

+250

Anytime

+750

Joseph Paintsil (Galaxy)

First

+290

Anytime

+850

Max Arfsten (Columbus)

First

+300

Anytime

+900

Marco Reus (Galaxy)

First

+340

Anytime

+1000

Matheus Nascimento (Galaxy)

First

+370

Anytime

+1150

Erik Thommy (Galaxy)

First

+420

Anytime

+1200

Dylan Chambost (Columbus)

First

+540

Anytime

+1600

André Gomes (Columbus)

First

+550

Anytime

+1600

Sean Zawadzski (Columbus)

First

+600

Anytime

+1800

Rudy Camacho (Columbus)

First

+700

Anytime

+2200

Steven Moreira (Columbus)

First

+700

Anytime

+2200

Malte Amundsen (Columbus)

First

+750

Anytime

+2200

Columbus have not triumphed at Lower.com Field in three straight matches. Henrik Rydstroem's side have secured four wins, three draws and three defeats in the last 10 home matches, scoring an average of 1.40 goals per game and conceding 1.00.

LA Galaxy haven’t lost any of their past three away games. Los Galácticos have six draws, three losses and one victory in the last 10 away matches, recording an average of 1.50 goals per game and conceding 2.00.

The last Lower.com Field meeting saw Columbus beat Galaxy 2-0.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
Columbus Crew Home Stats		4-3-3	2.40	1.40	1.00	5	5	6	4
LA Galaxy Away Stats		1-6-3	3.50	1.50	2.00	7	3	10	0

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

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Columbus Crew vs LA Galaxy Lineups & Team News

Make sure you're up to date on the Columbus vs Galaxy team news before betting. We’ll update you with predicted and confirmed MLS lineups plus current injury reports.

Columbus Crew Team Page LA Galaxy Team Page

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