Puebla vs Santos Laguna Prediction, Betting Tips, Lineups & Odds | 22 Aug 2026

Puebla vs Santos Laguna Predictions

Main Match Prediction

Puebla To Win @ +108

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There’s a strong chance that we’ll see Puebla record a victory and they are priced at +108 to beat Santos Laguna. We think that the Full-Time Result market offers bettors plenty of value.

Take a closer look at our complete Puebla vs Santos Laguna betting analysis, which presents a full breakdown of our main match prediction, plus our correct score prediction, player prop picks, corners prediction and bet builder tips.

Puebla vs Santos Laguna Preview

Puebla go head-to-head with Santos Laguna at Estadio Cuahutehmoc, with kick-off set for 21:00 on Saturday 22 August.

Club Puebla won their last game 3-2. This was an away victory at Estadio Miguel Hidalgo against Pachuca. La Franja had 40% of possession and four shots on target, with Emiliano Gomez, Kevin Velasco and Facundo Almada each scoring one goal.

Santos Laguna suffered a fourth straight defeat when losing 1-0 in their previous game. This was at home to Guadalajara at Estadio Nuevo Corona. Renato Paiva's team finished with just 39% possession and had two shots on goal.

H2H: Santos 2-1 Winners in Last H2H Battle

Santos won the last clash between the pair. Enjoying a 2-1 home triumph when facing Puebla at Estadio Nuevo Corona. In the previous 10 H2H meetings, there have been four wins apiece and two draws.

Liga MX		G	W	D	L	GF	GA	GD	GD	P
9	Puebla	11	4	3	4	12	13	-1	12:13	15
14	Santos Laguna	11	4	1	6	12	16	-4	12:16	13

View Full Table

2 wins, 6 losses and 2 draws, averaging 1.0 goals from 3.1 shots on goal and 6.8 attempts. Club Puebla have had 40.8% possession and 3.7 corners per game. On average, their opponents have scored 1.8 goals from 4.9 shots on goal and 12.4 attempts, while being awarded 6.9 corners.

Emiliano Gomez is the top scorer with 2 goals, while Kevin Velasco, Facundo Almada, Eduardo Mustre and Fernando Monarrez each have 1. Alberto Herrera is the leading assists maker on 2.

Santos have 2 victories, 7 defeats and 1 draw, with an average of 1.0 goals from 3.3 shots on goal and 8.2 attempts. There’s been an average of 46.6% possession, 5.4 corners awarded and 5.0 corners against, while they’ve conceded 1.7 goals from 5.9 shots on goal and 12.4 attempts.

Lucas Di Yorio is the leading scorer with 3 goals, followed by Aldo Lopez on 2, with Eduardo Aguirre and two others bagging 1. Ezequiel Bullaude has had 3 assists in the previous 10 games.

Confirmed Lineups

Puebla confirmed lineup (4-4-1-1): Daniel Gutierrez (GK), Iker Moreno, Facundo Almada, Juan Pablo Vargas, Fernando Monarrez, Brayan Garnica, Alejandro Organista, Alonso Ramirez, Carlos Baltazar, Kevin Velasco, Eduardo Mustre.

Santos Laguna confirmed lineup (4-2-3-1): Carlos Acevedo (GK), Mauricio Cuevas, Franco Pardo, Felipe Sanchez, Emmanuel Echeverria, Salvador Mariscal, Aldo Lopez, Diego Gonzalez, Fran Villalba, Ezequiel Bullaude, Eduardo Aguirre.

Main Match Prediction

We’re keeping things simple with our standout bet considering that Puebla are currently priced at +108. We think they can secure a victory in this Liga MX match and the hosts looks a value play.

Key stats supporting our main match prediction (league matches):

• Santos have lost their last 5 games on the road.
• Santos have lost 8 of their last 10 games on the road.
• Santos have lost 15 of their last 19 games on the road.

The Liga MX form is always taken into consideration and it’s great to combine this with team news as it becomes available. In order to provide expert football betting tips, the latest stats are analysed so that we have the best information.

The latest betting odds imply that our pick has a 48.1% prospect of winning. However, our tipsters in-depth research has found that the actual probability is between 55-60%. This wager can therefore be backed with confidence.

The Asian Handicap provide a range of alternatives when it comes to backing Puebla. There’s a chance to get bigger odds if you think that a sizeable win can be achieved.

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Puebla To Win @ +108 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Aug 21, 03:27). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Puebla 2 - 1 Santos

There’s plenty of juice to be found by backing Puebla to win 2-1. We can’t pass up the odds of +600 when it comes to correct score betting and it’s a fun wager.

Player Prop Picks

Top Pick: Fernando Monárrez Over 0.5 Shots On Target -114

Fernando Monárrez (Puebla) can be wagered to register a minimum of one shot on goal at -114. Those wanting to back him should certainly look at the Shots on Target betting odds available.

Latest Fernando Monárrez Player Prop Odds

Goalscorer

Anytime

+310

First

+850

Shots On Target

Over 0.5

-111

Under 0.5

-

---

Kevin Velasco To Score +230

Kevin Velasco (Puebla) can be backed at +230 to be among the goals. We’ll happily take the odds that he is able to score at least one goal when it comes to wagering on Anytime Goalscorer.

Latest Kevin Velasco Player Prop Odds

Goalscorer

Anytime

+230

First

+650

Shots On Target

Over 0.5

-143

Under 0.5

-

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Corners Prediction

Santos Over 4.5 Corners +110

The 4.5 corners line has been covered by Santos in three straight away games, while the past four Puebla home matches have seen over 4.5 corners conceded. We endorse betting on the +110 that Santos successfully cover the line, with this Team Corners wager hopefully providing a return.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

Puebla

Total

10.60 3.70 6.90

Home

11.60 4.20 7.40

Away

9.10 3.90 5.20

Santos

Total

10.40 5.40 5.00

Home

9.60 4.90 4.70

Away

9.10 5.10 4.00

Latest Corner Odds

Total Corners

Over 9.5

-143

Under 9.5

-104

Puebla Corners

Over 5.5

-103

Under 5.5

-152

Santos Corners

Over 4.5

-103

Under 4.5

-152

Most Corners

1

-147

X

+650

2

+143

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Puebla vs Santos Laguna Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Club Puebla are forecasted to have a 48% chance of triumphing in this Liga MX encounter according to the bookmakers. It leads to their latest betting odds being +108. Santos Laguna are trading at a bigger price than their opponents and the outsiders can be backed at +210.

There are various ways to back Puebla and one option is the Asian Handicap -0.25. There’s -122 currently available that they beat Santos and there’s half a stake refund if the scoreline ends level.

The Total Goals odds suggest that Over 2.5 is a strong probability in this contest. A different approach is a Both Teams to Score bet and Yes has been priced at -204.

The recommended betting sites push the boat out to ensure that football bettors can select from hundreds of markets. You can access them for every Liga MX game before making a decision.

Full-Time Result

1

+108

X

+250

2

+210

Half-Time Result

1

+140

X

+123

2

+250

Double Chance

1X

-294

12

-370

X2

-143

Draw No Bet

1

-192

2

+125

Asian Handicap

1 Hcp -0.25

-122

2 Hcp +0.25

-110

Total Goals

Under 2.5

+117

Over 2.5

-164

Both Teams to Score

Yes

-204

No

+133

Emiliano Gomez is the First Goalscorer favourite at +420. Alternatively, there’s the opportunity to simply back him to find the net anytime at +145.

Emiliano Gomez (Puebla)

First

+420

Anytime

+145

Lucas Di Yorio (Santos)

First

+500

Anytime

+180

Kevin Velasco (Puebla)

First

+650

Anytime

+230

Eduardo Aguirre (Santos)

First

+650

Anytime

+230

Omar Moreno (Puebla)

First

+700

Anytime

+260

Ignacio Maestro Puch (Puebla)

First

+750

Anytime

+280

Ramiro Sordo (Santos)

First

+800

Anytime

+280

Iker Moreno (Puebla)

First

+850

Anytime

+300

Ezequiel Bullaude (Santos)

First

+900

Anytime

+300

Fernando Monárrez (Puebla)

First

+850

Anytime

+310

Diego González (Santos)

First

+950

Anytime

+350

Fran Villalba (Santos)

First

+1000

Anytime

+380

Sergio Sanabria (Puebla)

First

+1100

Anytime

+400

Alejandro Organista (Puebla)

First

+1200

Anytime

+420

Raúl Castillo (Puebla)

First

+1200

Anytime

+475

Salvador Mariscal Murra (Santos)

First

+1500

Anytime

+550

Facundo Almada (Puebla)

First

+1600

Anytime

+600

Jair Díaz (Puebla)

First

+1700

Anytime

+600

Alberto Herrera (Puebla)

First

+1700

Anytime

+650

Javier Güemez (Santos)

First

+1800

Anytime

+650

Alonso Ramírez (Puebla)

First

+1800

Anytime

+700

Emmanuel Echeverria (Santos)

First

+2200

Anytime

+800

Carlos Gruezo (Santos)

First

+2200

Anytime

+850

Efraín Orona (Santos)

First

+2200

Anytime

+850

Lucas Di Yorio (Santos)

Over 0.5

-222

Under 0.5

-

Kevin Velasco (Puebla)

Over 0.5

-143

Under 0.5

-

Omar Moreno (Puebla)

Over 0.5

-143

Under 0.5

-

Eduardo Aguirre (Santos)

Over 0.5

-137

Under 0.5

-

Ignacio Maestro Puch (Puebla)

Over 0.5

-128

Under 0.5

-

Ramiro Sordo (Santos)

Over 0.5

-116

Under 0.5

-

Fernando Monárrez (Puebla)

Over 0.5

-111

Under 0.5

-

Ezequiel Bullaude (Santos)

Over 0.5

-109

Under 0.5

-

Iker Moreno (Puebla)

Over 0.5

-103

Under 0.5

-

Diego González (Santos)

Over 0.5

-100

Under 0.5

-

Emiliano Gomez (Puebla)

Over 1.5

+125

Under 1.5

-

Fran Villalba (Santos)

Over 0.5

+125

Under 0.5

-

Sergio Sanabria (Puebla)

Over 0.5

+140

Under 0.5

-

Alejandro Organista (Puebla)

Over 0.5

+140

Under 0.5

-

Raúl Castillo (Puebla)

Over 0.5

+155

Under 0.5

-

Salvador Mariscal Murra (Santos)

Over 0.5

+195

Under 0.5

-

Alberto Herrera (Puebla)

Over 0.5

+200

Under 0.5

-

Facundo Almada (Puebla)

Over 0.5

+210

Under 0.5

-

Jair Díaz (Puebla)

Over 0.5

+215

Under 0.5

-

Alonso Ramírez (Puebla)

Over 0.5

+230

Under 0.5

-

Javier Güemez (Santos)

Over 0.5

+235

Under 0.5

-

Emmanuel Echeverria (Santos)

Over 0.5

+290

Under 0.5

-

Efraín Orona (Santos)

Over 0.5

+330

Under 0.5

-

Carlos Gruezo (Santos)

Over 0.5

+350

Under 0.5

-

Stats: Last 10 Liga MX matches only.
Puebla have not triumphed at Estadio Cuahutehmoc in five straight matches. La Franja have recorded four draws, four losses and two wins in the previous 10 home games, scoring an average of 1.00 goals per match and conceding 1.40.

Santos Laguna are on a five game losing streak on the road. Renato Paiva's team have eight defeats, one win and one draw in the last 10 away games, scoring an average of 1.00 goals per match and conceding 2.90.

Puebla beat Santos 1-0 when they last met at Estadio Cuahutehmoc. It’s been four Puebla victories, three draws and two Santos wins in the previous 9 H2H games at Estadio Cuahutehmoc.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
Puebla Home Stats		2-4-4	2.40	1.00	1.40	5	5	6	4
Santos Laguna Away Stats		1-1-8	3.90	1.00	2.90	9	1	6	4

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

Puebla vs Santos Laguna Lineups & Team News

Be smart with your bets — check the Puebla vs Santos team news beforehand. We’ll share the predicted and confirmed lineups for the Liga MX together with updated injury news.

Puebla Team Page Santos Laguna Team Page

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