San Luis vs Santos Laguna Prediction, Betting Tips, Lineups & Odds | 11 Oct 2026
San Luis vs Santos Laguna Predictions
The Total Goals market can provide the best betting angle considering that odds of -167 are available when it comes to Over 2.5. We expect this total to be covered when San Luis line up against Santos Laguna.
Our San Luis vs Santos Laguna betting coverage includes detailed reasoning for the main match prediction, plus our correct score prediction, player prop picks, corners prediction and bet builder tips.
San Luis vs Santos Laguna Preview
San Luis take on Santos Laguna at Estadio Alfonso Lastras, with kick-off set for 19:00 on Sunday 11 October.
Atlético San Luis have won back-to-back Liga MX games. A 3-2 triumph recently occurred away at Olimpico Universitario when playing Pumas UNAM. Los Atléticos had 46% possession and totalled seven shots on target, with Sebastien Lamonge netting twice along with a goal for David Rodriguez.
Santos Laguna beat Pachuca in their previous game, making it three consecutive wins. It was a 1-0 home triumph at Estadio Nuevo Corona. Renato Paiva's men had nine shots on goal and enjoyed 55% possession, with Fran Villalba scoring a 45th minute winner.
H2H: San Luis Won 2-0 in Teams’ Last Encounter
San Luis have five consecutive victories against Santos. Their last encounter saw San Luis make home advantage count at Estadio Alfonso Lastras, winning 2-0. The previous 10 H2H games have included five wins for San Luis, four triumphs for Santos and a single draw.
| Liga MX | G | W | D | L | GF | GA | GD | GD | P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 14 |  San Luis |
10 | 3 | 3 | 4 | 14 | 18 | -4 | 14:18 | 12 |
| 16 |  Santos Laguna |
10 | 3 | 1 | 6 | 10 | 15 | -5 | 10:15 | 10 |
San Luis have 3 wins, 4 losses and 3 draws, averaging 1.4 goals from 4.5 shots on goal and 11.9 attempts. Diego Mejia's team have averaged 52.7% possession and 2.9 corners per game, with the opposition getting 1.8 goals from 5.1 shots on goal, 16.4 attempts and 6.6 corners.
Sebastien Lamonge, David Rodriguez and Rafa Llorente are joint-top scorers with 3 goals on the board. Leonardo Flores is the top assists maker on 2.
Santos have won 3, lost 6 and drawn 1, with an average of 1.0 goals from 12.8 attempts and 4.3 shots on goal. There’s been an average of 50.9% possession, 7.8 corners awarded and 5.5 corners against them, while they’ve conceded 1.5 goals from 15.4 attempts and 6.1 shots on goal.
Ezequiel Bullaude got 3 goals, Fran Villalba notched 2, while Kevin Palacios and two other players scored 1. Fran Villalba and Mauricio Cuevas have clocked up 2 assists each in the last 10 games.
Predicted & Confirmed Lineups
San Luis predicted lineup (3-4-3): Gibrán Lajud (GK), Benjamín Galindo, Aldo Cruz, Eduardo Águila, Román Torres, Óscar Macías, Sébastien Salles Lamonge, Anderson Duarte, David Rodriguez, Felipe Mora, Rafael Llorente.
Santos Laguna predicted lineup (3-4-3): Carlos Acevedo Lopez (GK), Franco Pardo, Felipe Sanchez, Efraín Orona, Mauricio Cuevas, Facundo Caseres, Fran Villalba, Diego González, Kevin Palacios, Esteban Lozano, Ezequiel Bullaude.
Main Match Prediction
We look set for a relatively high-scoring Liga MX clash, with Over 2.5 looking like the best pick when it comes to getting the best possible value. There are odds of -167 for this outcome and that looks worth taking.
Key stats supporting our main match prediction (league matches):
The Liga MX experts at Sportsgambler.com always keep close tabs on team news. We also use a form guide for our football betting tips along with checking out the stats that are going to help inform our final decision.
The betting odds at the top bookies suggest our pick carries a 62.5% chance of winning. In our opinion, there’s actually a probability of success between 65-70%. It’s why we think it’s worth placing this bet.
The Over 2.5 Goals pick can be combined with other selections as part of a Bet Builder. You can get much bigger odds by going down this route although you need all picks to win.
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Correct Score Prediction
2
-
2
Santos
We think there’s a chance of a 2-2 draw and this can be backed at odds of +800. We like placing a bet on correct score due to the fun element and the big potential return.
Player Prop Picks
Anderson Duarte (San Luis) can be backed to record at least one shot on goal at -115. Shots on Target bettors should definitely consider him at the available odds and we’ll have a play.
Fran Villalba (Santos) has netted two goals in his past five Liga MX matches. We believe this is the best of the player props, with a healthy +400 available when it comes to betting him to score at any time.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Corners Prediction
San Luis have not covered the 5.5 corners line in ten consecutive matches. We recommend backing the -132 that San Luis aren’t able to cover the line, with this Team Corners wager hopefully providing a return.
San Luis
Santos
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Bet Builder Tips
A same-game multi can provide entertainment and we’ve got at least three goals in total, Santos with an Asian Handicap of +0.5 merged with Anderson Duarte (San Luis) to record one or more shots on target.
A bet builder provides an exciting opportunity to follow various picks for the same football match. The bookies have created this personalised betting tool where you can hand-pick different selections and combine the odds together.
San Luis vs Santos Laguna Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
For this Liga MX encounter, the bookmakers have Atlético San Luis as the -114 favourites to win. This therefore implies that they have a 53% chance of triumphing. For those wanting to back Santos Laguna, you will find +255 about this outsider.
San Luis are -116 on the Asian Handicap -0.5 which is like backing them on the Full-Time Result market. Alternatively, you can get -118 for Santos +0.5 and get the draw on your side.
The Total Goals odds suggest that Over 2.5 is a strong probability in this contest. Should you expect both teams score, then the BTTS Yes option is available at -189.
Hundreds of markets are now a guarantee for each of the Liga MX games, with the best football betting sites making sure that customers have quality options.
Felipe Mora is priced at +460 when it comes to First Goalscorer. He’s the favourite and also available at odds of +170 to find the net anytime.
Stats: Last 10 Liga MX matches only.
San Luis have collected four defeats, three wins and three draws in the previous 10 home matches, scoring an average of 1.40 goals per game and conceding 1.40.
Santos have recorded seven defeats, two victories and one draw in the previous 10 away matches, netting an average of 1.30 goals per game and conceding 2.40.
The past meeting at Estadio Alfonso Lastras saw San Luis defeat Santos 2-0. The past 7 H2H games at Estadio Alfonso Lastras have resulted in three wins apiece along with a draw.
| Last 10 League Games | W-D-L | G | GF | GA | O2.5 | U2.5 | B-Y | B-No | |
|---|---|---|---|---|---|---|---|---|---|
| San Luis Home Stats |
3-3-4 | 2.80 | 1.40 | 1.40 | 5 | 5 | 6 | 4 | |
| Santos Laguna Away Stats |
2-1-7 | 3.70 | 1.30 | 2.40 | 8 | 2 | 6 | 4 | |
- W-D-L = Wins-Draws-Losses
- G = Avg. Goals
- GF = Avg. Goals For
- GA = Avg. Goals Against
- O2.5 = Matches Over 2.5 Goals
- U2.5 = Matches Under 2.5 Goals
- B-Y = Matches BTTS Yes
- B-No = Matches BTTS No
- Liga MX: 23/04 2026 San Luis 2 Santos 0
- Liga MX: 22/09 2025 Santos 1 San Luis 4
- Liga MX: 31/03 2025 Santos 2 San Luis 3
- Liga MX: 29/09 2024 San Luis 3 Santos 1
- Liga MX: 29/04 2024 Santos 0 San Luis 3
- Liga MX: 12/11 2023 San Luis 0 Santos 2
- Liga MX: 19/02 2023 San Luis 1 Santos 1
- Liga MX: 29/08 2022 Santos 4 San Luis 1
- Liga MX: 01/05 2022 San Luis 1 Santos 3
- Liga MX: 21/11 2021 Santos 2 San Luis 0
San Luis League Stats
Santos Laguna League Stats
- 3 wins, 4 defeats and 3 draws in the previous 10 matches
- 3 wins, 4 defeats and 3 draws in the previous 10 home matches
- 3 wins, 6 defeats and 1 draw in the previous 10 matches
- 2 wins, 7 defeats and 1 draw in the previous 10 away matches
- An average of 1.40 goals scored and 1.80 conceded in the previous 10 matches
- An average of 1.40 goals scored and 1.40 conceded in the previous 10 home matches
- An average of 3.20 goals per game in the previous 10 matches
- An average of 2.80 goals per game in the previous 10 home matches
- BTTS Yes in 6 of the previous 10 matches
- BTTS Yes in 6 of the previous 10 home matches
- Over 2.5 Goals in 7 of the previous 10 matches
- Over 2.5 Goals in 5 of the previous 10 home matches
- An average of 1.00 goals scored and 1.50 conceded in the previous 10 matches
- An average of 1.30 goals scored and 2.40 conceded in the previous 10 away matches
- An average of 2.50 goals per game in the previous 10 matches
- An average of 3.70 goals per game in the previous 10 away matches
- BTTS Yes in 4 of the previous 10 matches
- BTTS Yes in 6 of the previous 10 away matches
- Over 2.5 Goals in 5 of the previous 10 matches
- Over 2.5 Goals in 8 of the previous 10 away matches
- An average of 2.90 corners awarded and 6.60 corners conceded in the last 10 matches
- An average of 4.30 corners awarded and 3.00 corners against in the last 10 home matches
- An average of 9.50 corners awarded in the last 10 matches
- An average of 7.30 corners awarded in the last 10 home matches
- Had the most corners in 3 and least corners in 7 of the last 10 matches
- Had the most corners in 7 and least corners in 3 of the last 10 home matches
- An average of 7.80 corners awarded and 5.50 corners conceded in the last 10 matches
- An average of 5.60 corners awarded and 5.40 corners against in the last 10 away matches
- An average of 13.30 corners awarded in the last 10 matches
- An average of 11.00 corners awarded in the last 10 away matches
- Had the most corners in 6 and least corners in 3 of the last 10 matches
- Had the most corners in 4 and least corners in 4 of the last 10 away matches
- An average of 52.70% possession in the last 10 matches
- An average of 55.90% possession in the last 10 home matches
- Most possession in 5 of the last 10 matches
- Most possession in 7 of the last 10 home matches
- An average of 50.90% possession in the last 10 matches
- An average of 49.10% possession in the last 10 away matches
- Most possession in 6 of the last 10 matches
- Most possession in 4 of the last 10 away matches
- Top Scorers for San Luis this season are David Rodriguez (3), Rafa Llorente (3), Sebastien Lamonge (3)
- Top Assistors for San Luis this season are Leonardo Flores (2), David Rodriguez (1), Felipe Mora (1)
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San Luis vs Santos Laguna Lineups & Team News
Be smart with your bets — check the San Luis vs Santos team news beforehand. Get the latest predicted and confirmed Liga MX lineups and injury news right here.
San Luis Predicted Lineup 3-4-3
Santos Laguna Predicted Lineup 3-4-3
San Luis Predicted Lineup 3-4-3
Santos Laguna Predicted Lineup 3-4-3
Previous San Luis Lineups
Previous Santos Laguna Lineups
Injuries & Suspensions
San Luis Player Stats & Squad
Manager: Diego Mejia
Santos Laguna Player Stats & Squad
Liga MX Table| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | América | 9 | 6 | 2 | 1 | 21:10 | 20 |
| 2 | Toluca | 11 | 6 | 2 | 3 | 25:15 | 20 |
| 3 | Guadalajara | 10 | 5 | 3 | 2 | 17:10 | 18 |
| 4 | León | 11 | 5 | 3 | 3 | 15:12 | 18 |
| 5 | Querétaro | 9 | 5 | 2 | 2 | 13:8 | 17 |
| 6 | Atlas | 10 | 5 | 2 | 3 | 16:17 | 17 |
| 7 | Cruz Azul | 10 | 5 | 1 | 4 | 19:18 | 16 |
| 8 | Puebla | 11 | 4 | 3 | 4 | 12:13 | 15 |
| 9 | Tijuana | 9 | 4 | 2 | 3 | 14:13 | 14 |
| 10 | Monterrey | 9 | 4 | 1 | 4 | 16:14 | 13 |
| 11 | Tigres | 11 | 3 | 4 | 4 | 13:15 | 13 |
| 12 | Pachuca | 10 | 3 | 3 | 4 | 15:11 | 12 |
| 13 | Pumas | 10 | 3 | 3 | 4 | 14:16 | 12 |
| 14 | San Luis | 10 | 3 | 3 | 4 | 14:18 | 12 |
| 15 | Atlante | 10 | 2 | 5 | 3 | 12:15 | 11 |
| 16 | Santos Laguna | 10 | 3 | 1 | 6 | 10:15 | 10 |
| 17 | Necaxa | 10 | 2 | 2 | 6 | 12:20 | 8 |
| 18 | Juárez | 10 | 1 | 0 | 9 | 7:25 | 3 |
| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | León | 5 | 4 | 0 | 1 | 9:4 | 12 |
| 2 | Tijuana | 6 | 4 | 0 | 2 | 10:6 | 12 |
| 3 | Tigres | 5 | 3 | 2 | 0 | 9:5 | 11 |
| 4 | América | 4 | 3 | 1 | 0 | 10:2 | 10 |
| 5 | Monterrey | 5 | 3 | 1 | 1 | 11:6 | 10 |
| 6 | Cruz Azul | 6 | 3 | 1 | 2 | 12:12 | 10 |
| 7 | Toluca | 5 | 3 | 0 | 2 | 15:8 | 9 |
| 8 | Guadalajara | 5 | 3 | 0 | 2 | 9:6 | 9 |
| 9 | Santos Laguna | 5 | 2 | 1 | 2 | 3:3 | 7 |
| 10 | Puebla | 5 | 1 | 3 | 1 | 6:6 | 6 |
| 11 | Atlante | 5 | 1 | 3 | 1 | 6:7 | 6 |
| 12 | Necaxa | 6 | 2 | 0 | 4 | 8:12 | 6 |
| 13 | Pumas | 5 | 1 | 2 | 2 | 6:8 | 5 |
| 14 | San Luis | 5 | 1 | 2 | 2 | 6:8 | 5 |
| 15 | Atlas | 5 | 1 | 2 | 2 | 5:8 | 5 |
| 16 | Querétaro | 4 | 1 | 1 | 2 | 5:6 | 4 |
| 17 | Juárez | 5 | 1 | 0 | 4 | 4:10 | 3 |
| 18 | Pachuca | 4 | 0 | 2 | 2 | 6:8 | 2 |
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