Toluca vs Santos Laguna Prediction, Betting Tips, Lineups & Odds | 20 Sep 2026
Toluca vs Santos Laguna Predictions
Toluca could enjoy a convincing win against Santos Laguna. We’re backing them at -104 with a -2 Asian Handicap, meaning money back for a two-goal victory and a bigger return if the favourites triumph by more.
Continue reading for our full Toluca vs Santos Laguna betting analysis, outlining the core arguments for our main match prediction, alongside our correct score prediction, player prop picks, corners prediction and bet builder tips.
Toluca vs Santos Laguna Preview
Toluca clash with Santos Laguna at Estadio Nemesio Diez, with kick-off set for 20:00 on Sunday 20 September.
Deportivo Toluca won their last game 1-0, making it four on the spin. This was an away win at Estadio Cuahutehmoc against Club Puebla. Antonio Mohamed's side boasted 57% possession and had three shots on target, with an own goal making the difference.
Santos Laguna have suffered four consecutive defeats away from home. In their previous game, they enjoyed a 2-1 home victory against Juárez at Estadio Nuevo Corona. Los Guerreros were 53% in the possession stakes and had ten shots on goal, while Ezequiel Bullaude and Esteban Lozano were both on target.
H2H: 8 Triumphs for Toluca in Previous 10 Head-to-Head Clashes
Toluca have three straight wins against Santos. In their last encounter, Toluca came out with a 3-1 home victory at Estadio Nemesio Diez. The previous 10 H2H meetings have involved Toluca winning eight times and Santos registering two victories.
| Liga MX | G | W | D | L | GF | GA | GD | GD | P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  Toluca |
8 | 6 | 1 | 1 | 18 | 6 | 12 | 18:6 | 19 |
| 17 |  Santos Laguna |
8 | 1 | 1 | 6 | 6 | 13 | -7 | 6:13 | 4 |
Deportivo Toluca have 6 wins, 3 losses and 1 draw, averaging 1.8 goals from 5.5 shots on goal and 15.4 attempts. Los Diablos Rojos have averaged 59.6% possession and 6.2 corners per match, conceding 0.9 goals and 4.9 corners from 3.6 shots on goal and 11.0 attempts.
Top scorer Federico Vinas has found the net 3 times, with Alexis Vega and Helinho getting 2 apiece. The leading assistor is Helinho with 2.
Santos have 2 victories, 7 defeats and 1 draw, with an average of 10.6 attempts, 3.4 shots on goal and 0.9 goals. The Comarca Lagunera club average 50.3% possession, 7.0 corners awarded and 5.7 corners against them, while 1.5 goals have been conceded from 6.3 shots on goal and 14.3 attempts.
Ezequiel Bullaude and Lucas Di Yorio have top scored with 2 goals, while Esteban Lozano is next on 1. Look no further than Ezequiel Bullaude for the top assist maker (4) in the last 10 games.
Predicted & Confirmed Lineups
Toluca predicted lineup (4-2-3-1): Luis García (GK), Diego Barbosa, Bruno Méndez, Federico Pereira, Everardo del Villar, Franco Romero, Jesús Gallardo, Federico Viñas, Jesús Angulo, Nicolas Castro, Paulinho.
Santos Laguna predicted lineup (3-4-3): Carlos Acevedo Lopez (GK), Franco Pardo, Felipe Sanchez, Efraín Orona, Mauricio Cuevas, Facundo Caseres, Fran Villalba, Diego González, Kevin Palacios, Ezequiel Bullaude, Eduardo Aguirre.
Main Match Prediction
Backing Toluca -2 at -104 could provide a nice return. There’s some insurance in this bet although we think this Liga MX clash will be a one-sided affair and the price looks attractive.
Key stats supporting our main match prediction (league matches):
Our football betting picks come from having access to off-the-press team news along with going through the Liga MX form guide. It’s also important to identify the key stats.
The latest odds at the best betting sites suggest our pick carries a 51% chance of winning. However, our research has found that the actual probability is between 55-60%. The bet can be recommended for this precise reason.
If you’re looking for a bigger potential return on your stake, there is always the alternative to move the line. Consider the odds and whether each line can be covered.
Get ahead in sports betting by reviewing our detailed bonus guide featuring the latest betting promo codes for the best welcome bonuses.
Correct Score Prediction
3
-
0
Santos
We’ve found an attractive bet at odds of +600 and it involves Toluca winning 3-0. We like a wager on correct score as there’s the chance to bank a bigger return.
Player Prop Picks
Ezequiel Bullaude (Santos) can be wagered at +140 to have one or more shots on goal. All things considered, we think that the betting odds are really appealing when it comes to backing him on the Shots Target market.
Nicolas Castro (Toluca) can be wagered at +200 to find the net. We believe this is the best of the player props, with healthy odds available when it comes to betting him to score at any time.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Corners Prediction
The 3.5 corners line has been covered by Santos in eight consecutive games, while Toluca have conceded 6.40 corners on average in their last 5 matches. The amount of Santos corners could be bigger than the Team Corners line suggests and that leads us to a bet at odds of -116.
Toluca
Santos
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Bet Builder Tips
There’s everything to like about this bet builder including Toluca on the Asian Handicap at -2, No on the Both Teams to Score market merged with Ezequiel Bullaude (Santos) to finish with a minimum of one shot on target.
We advise a bet builder as it can be a fun approach when betting on a football game. You require all predictions to be on the money and our readers enjoy placing a tailored wager on a specific encounter taking place.
Toluca vs Santos Laguna Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
With an estimated 83% chance of winning, the bookies are taking few chances with their -476 betting odds about Deportivo Toluca triumphing in this Liga MX clash. Santos Laguna are regarded as a long shot to win and you can back them at +950.
The Half-Time Result market means that your bet will always be settled at the interval. Toluca are -200, while Santos are alternatively priced at +600 and the draw is +195.
The odds suggest that Over 2.5 Goals is a strong probability in this exciting contest. If you’re anticipating that both teams will score, the BTTS Yes option can be wagered at -147.
It’s great that you can tap into hundreds of markets for every Liga MX match. Each of our recommended football betting sites provide exciting pre-match and In-Play betting options.
João Paulo Paulinho can be backed to find the net anytime at -125. There is the chance to back the market leader to score the first goal at +300.
Stats: Last 10 Liga MX matches only.
Toluca have landed three straight wins at Estadio Nemesio Diez. Antonio Mohamed's side have six victories, two draws and two defeats in the last 10 home matches, netting an average of 2.40 goals per game and conceding 1.00.
It’s now been seven straight Santos Laguna defeats on the road. Los Guerreros have eight defeats, one victory and one draw in the last 10 away matches, netting an average of 1.10 goals per game and conceding 2.40.
When the sides last met at Estadio Nemesio Diez, Toluca beat Santos 3-1. We’ve seen the previous 8 H2H meetings at Estadio Nemesio Diez involve six triumphs for Toluca, one draw and one win for Santos.
| Last 10 League Games | W-D-L | G | GF | GA | O2.5 | U2.5 | B-Y | B-No | |
|---|---|---|---|---|---|---|---|---|---|
| Toluca Home Stats |
6-2-2 | 3.40 | 2.40 | 1.00 | 6 | 4 | 7 | 3 | |
| Santos Laguna Away Stats |
1-1-8 | 3.50 | 1.10 | 2.40 | 8 | 2 | 6 | 4 | |
- W-D-L = Wins-Draws-Losses
- G = Avg. Goals
- GF = Avg. Goals For
- GA = Avg. Goals Against
- O2.5 = Matches Over 2.5 Goals
- U2.5 = Matches Under 2.5 Goals
- B-Y = Matches BTTS Yes
- B-No = Matches BTTS No
- Liga MX: 15/01 2026 Toluca 3 Santos 1
- Liga MX: 17/07 2025 Santos 2 Toluca 4
- Liga MX: 07/04 2025 Toluca 2 Santos 1
- Liga MX: 23/09 2024 Santos 2 Toluca 0
- Liga MX: 22/02 2024 Toluca 1 Santos 0
- Liga MX: 06/11 2023 Santos 3 Toluca 1
- Liga MX: 24/02 2023 Santos 0 Toluca 5
- Liga MX: 17/10 2022 Santos 1 Toluca 2
- Liga MX: 14/10 2022 Toluca 4 Santos 3
- Liga MX: 24/07 2022 Toluca 2 Santos 1
Toluca League Stats
Santos Laguna League Stats
- 6 wins, 3 defeats and 1 draw in the previous 10 matches
- 6 wins, 2 defeats and 2 draws in the previous 10 home matches
- 2 wins, 7 defeats and 1 draw in the previous 10 matches
- 1 win, 8 defeats and 1 draw in the previous 10 away matches
- An average of 1.80 goals scored and 0.90 conceded in the previous 10 matches
- An average of 2.40 goals scored and 1.00 conceded in the previous 10 home matches
- An average of 2.70 goals per game in the previous 10 matches
- An average of 3.40 goals per game in the previous 10 home matches
- BTTS Yes in 4 of the previous 10 matches
- BTTS Yes in 7 of the previous 10 home matches
- Over 2.5 Goals in 5 of the previous 10 matches
- Over 2.5 Goals in 6 of the previous 10 home matches
- An average of 0.90 goals scored and 1.50 conceded in the previous 10 matches
- An average of 1.10 goals scored and 2.40 conceded in the previous 10 away matches
- An average of 2.40 goals per game in the previous 10 matches
- An average of 3.50 goals per game in the previous 10 away matches
- BTTS Yes in 3 of the previous 10 matches
- BTTS Yes in 6 of the previous 10 away matches
- Over 2.5 Goals in 5 of the previous 10 matches
- Over 2.5 Goals in 8 of the previous 10 away matches
- An average of 6.20 corners awarded and 4.90 corners conceded in the last 10 matches
- An average of 5.70 corners awarded and 3.80 corners against in the last 10 home matches
- An average of 11.10 corners awarded in the last 10 matches
- An average of 9.50 corners awarded in the last 10 home matches
- Had the most corners in 5 and least corners in 5 of the last 10 matches
- Had the most corners in 7 and least corners in 3 of the last 10 home matches
- An average of 7.00 corners awarded and 5.70 corners conceded in the last 10 matches
- An average of 5.50 corners awarded and 5.00 corners against in the last 10 away matches
- An average of 12.70 corners awarded in the last 10 matches
- An average of 10.50 corners awarded in the last 10 away matches
- Had the most corners in 4 and least corners in 5 of the last 10 matches
- Had the most corners in 4 and least corners in 4 of the last 10 away matches
- An average of 59.60% possession in the last 10 matches
- An average of 58.20% possession in the last 10 home matches
- Most possession in 9 of the last 10 matches
- Most possession in 8 of the last 10 home matches
- An average of 50.30% possession in the last 10 matches
- An average of 48.70% possession in the last 10 away matches
- Most possession in 6 of the last 10 matches
- Most possession in 4 of the last 10 away matches
- Top Scorers for Toluca this season are Federico Vinas (3), Alexis Vega (2), Helinho (2)
- Top Assistors for Toluca this season are Helinho (2), Bruno Mendez (1), Everardo Lopez (1)
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Toluca vs Santos Laguna Lineups & Team News
Check the Toluca vs Santos team news before you place your bets. Stay in the know with our predicted and confirmed Liga MX lineups and the latest on injuries.
Deportivo Toluca Predicted Lineup 4-2-3-1
Santos Laguna Predicted Lineup 3-4-3
Deportivo Toluca Predicted Lineup 4-2-3-1
Santos Laguna Predicted Lineup 3-4-3
Previous Toluca Lineups
Previous Santos Laguna Lineups
Injuries & Suspensions
Toluca Player Stats & Squad
Manager: Antonio Mohamed
Santos Laguna Player Stats & Squad
Liga MX Table| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | Toluca | 8 | 6 | 1 | 1 | 18:6 | 19 |
| 2 | Guadalajara | 8 | 5 | 2 | 1 | 15:6 | 17 |
| 3 | América | 7 | 5 | 1 | 1 | 15:6 | 16 |
| 4 | Cruz Azul | 8 | 5 | 0 | 3 | 16:14 | 15 |
| 5 | Puebla | 9 | 4 | 2 | 3 | 11:11 | 14 |
| 6 | Querétaro | 7 | 4 | 1 | 2 | 10:7 | 13 |
| 7 | León | 8 | 4 | 1 | 3 | 11:9 | 13 |
| 8 | Tijuana | 7 | 4 | 1 | 2 | 10:8 | 13 |
| 9 | Atlas | 8 | 4 | 1 | 3 | 12:14 | 13 |
| 10 | Pachuca | 8 | 3 | 2 | 3 | 13:8 | 11 |
| 11 | Pumas | 8 | 3 | 2 | 3 | 11:12 | 11 |
| 12 | Monterrey | 7 | 3 | 1 | 3 | 13:10 | 10 |
| 13 | Necaxa | 8 | 2 | 2 | 4 | 9:13 | 8 |
| 14 | Atlante | 9 | 1 | 5 | 3 | 8:13 | 8 |
| 15 | Tigres | 9 | 1 | 4 | 4 | 9:13 | 7 |
| 16 | San Luis | 8 | 1 | 3 | 4 | 8:15 | 6 |
| 17 | Santos Laguna | 8 | 1 | 1 | 6 | 6:13 | 4 |
| 18 | Juárez | 9 | 1 | 0 | 8 | 6:23 | 3 |
| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | Tijuana | 5 | 4 | 0 | 1 | 8:3 | 12 |
| 2 | Toluca | 4 | 3 | 0 | 1 | 13:5 | 9 |
| 3 | América | 3 | 3 | 0 | 0 | 8:0 | 9 |
| 4 | Guadalajara | 4 | 3 | 0 | 1 | 9:4 | 9 |
| 5 | León | 4 | 3 | 0 | 1 | 7:3 | 9 |
| 6 | Cruz Azul | 5 | 3 | 0 | 2 | 9:9 | 9 |
| 7 | Monterrey | 4 | 2 | 1 | 1 | 10:6 | 7 |
| 8 | Necaxa | 5 | 2 | 0 | 3 | 6:8 | 6 |
| 9 | Tigres | 3 | 1 | 2 | 0 | 5:3 | 5 |
| 10 | Puebla | 4 | 1 | 2 | 1 | 5:5 | 5 |
| 11 | Pumas | 4 | 1 | 2 | 1 | 4:5 | 5 |
| 12 | Santos Laguna | 4 | 1 | 1 | 2 | 2:3 | 4 |
| 13 | Atlas | 4 | 1 | 1 | 2 | 4:7 | 4 |
| 14 | Querétaro | 3 | 1 | 0 | 2 | 4:5 | 3 |
| 15 | Atlante | 4 | 0 | 3 | 1 | 2:5 | 3 |
| 16 | Juárez | 5 | 1 | 0 | 4 | 4:10 | 3 |
| 17 | San Luis | 4 | 0 | 2 | 2 | 3:7 | 2 |
| 18 | Pachuca | 3 | 0 | 1 | 2 | 4:6 | 1 |
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