Louisville vs North Carolina Prediction, Picks & Odds | 14 Nov 2026
Louisville vs North Carolina Predictions
Our prediction is that Louisville are going to cover the -3.5 on the spread. You can get -115 that there’s a bigger margin of victory against North Carolina.
Our expert Louisville vs North Carolina betting picks include our Best Bet, Player Props, Same Game Parlay and Correct Score Prediction. Explore each section for the full analysis behind the plays.
Louisville vs North Carolina Preview
Louisville go up against North Carolina at Kenan Stadium, with kickoff scheduled for 19:00 on Saturday, November 14.
Louisville Cardinals have won four on the spin, triumphing 44-17 in their previous game. This was on the road against Georgia Tech Yellow Jackets at Bobby Dodd Stadium.
North Carolina Tar Heels have now suffered three straight home defeats. In their last game, they won on the road at Rentschler Field when beating UConn Huskies 38-21.
Quarterbacks
Lincoln Kienholz
Billy Edwards Jr.
Best Bet
Our pick is for Louisville to cover the appealing -3.5 line in this college football matchup. They should be able to win by a more comfortable margin and odds of -115 are available for the favorites.
Key stats supporting our main match prediction:
The CFB handicappers at Sportsgambler.com always keep close tabs on team news as it develops. We also rely on recent form and key stats to help shape our picks and guide the final call.
Louisville -3.5 Probability
According to the best betting apps, there’s a 53.5% chance that our pick is settled as a winner. However, our research has found that the actual probability is closer to 60%. This is why we regard this as a value wager.
Looking for more juice from your selection? By moving the betting line, you are able to get a bigger price although you will need to take a riskier wager.
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Player Prop Picks
The odds for Lincoln Kienholz (Louisville) to accumulate over 234.5 passing yards are -114. We're confident in him covering the QB Passing Yards line and hitting our Over bet.
Keyjuan Brown (Louisville) is available at -114 to record more than 53.5 rushing yards. We can place a Player Rushing Yards bet with confidence, as we expect him to cover the line.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Pick
Our same game parlay pick is Louisville -3.5 on the spread, Over 59.5 and Lincoln Kienholz (Louisville) to go Over 234.5 passing yards.
A same game parlay is a fantastic option for bettors who want to focus their wagering on a single football game. You can predict different outcomes and see their odds combined before going ahead and placing this tailored bet.
Correct Score Prediction
38
-
30
North Carolina
There are lots of different ways to back the Cards on the correct score betting and something like 38-30 in their favor might be along the right lines at massive odds.
Louisville vs North Carolina Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
Louisville have the shortest price to win this college game, with the sportsbooks giving them a 63% probability due to their -169 Moneyline betting odds. The market suggests that North Carolina are least likely to win at +142.
The spread currently stands at 3.5 and the total points line is 59.5. There is no denying the popularity of wagering on the Totals. Those who wager Under 59.5 can get -115.
Whether you are betting pre-game or in-game on college football, the best sportsbooks let you feast on a wide range of game lines and team props. The selections are practically endless, and it’s fantastic to have so many options.
Receiving Yards
Rushing Yards
Passing Yards
North Carolina Looking Weak in Front of Their Fans
North Carolina have endured three straight losses at Kenan Stadium. They own a 3-7 mark in their past 10 home games, scoring 25.20 points per contest and conceding 26.50.
Louisville own a 7-3 mark in their past 10 games away from home, putting up 31.20 points per contest and giving up 26.50.
| Last 10 Games | W-L | P | PF | PA | O59.5 | U59.5 | |
|---|---|---|---|---|---|---|---|
 North Carolina Home Stats |
3-7 | 51.70 | 25.20 | 26.50 | 4 | 6 | |
 Louisville Away Stats |
7-3 | 57.70 | 31.20 | 26.50 | 5 | 5 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O59.5 = Games Over 59.5 Points
- U59.5 = Games Under 59.5 Points
Latest regular season and playoff games stats.
Louisville Cardinals Stats
North Carolina Tar Heels Stats
- 7 wins and 3 defeats in the last 10 games
- 7 wins and 3 defeats in the last 10 games on the road
- -3.5 Betting Line: Have covered the spread in 7 of the last 10 games
- -3.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road
- +3.5 Betting Line: Have covered the spread in 7 of the last 10 games
- +3.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games
- Game Totals: An average of 64.90 pts in the previous 10 games
- Game Totals on the Road: An average of 57.70 pts in the previous 10 games on the road
- Over 59.5: Covered in 7 of the previous 10 games
- Over 59.5 on the Road: Covered in 5 of the previous 10 games on the road
- Team Totals: Have scored an average of 39.40 pts and allowed 25.50 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 31.20 pts and allowed 26.50 pts in the last 10 games on the road
- Game Totals: An average of 51.00 pts in the previous 10 games
- Game Totals at Home: An average of 51.70 pts in the previous 10 home games
- Over 59.5: Covered in 4 of the previous 10 games
- Over 59.5 at Home: Covered in 4 of the previous 10 home games
- Team Totals: Have scored an average of 26.30 pts and allowed 24.70 pts in the last 10 games
- Team Totals at Home: Have scored an average of 25.20 pts and allowed 26.50 pts in the last 10 home games
| Atlantic Coast | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Miami
|
8 | 1 | 405 | 173 | 232 | 4-0 | 4-1 | 1L |
Wake Forest
|
8 | 1 | 390 | 143 | 247 | 4-1 | 4-0 | 6W |
SMU
|
7 | 2 | 333 | 206 | 127 | 6-0 | 1-2 | 1W |
|
Louisville
|
6 | 3 | 367 | 233 | 134 | 4-1 | 2-2 | 4W |
Duke
|
7 | 2 | 297 | 117 | 180 | 4-1 | 3-1 | 3W |
Clemson
|
6 | 3 | 204 | 186 | 18 | 3-2 | 3-1 | 2W |
Pittsburgh
|
6 | 3 | 287 | 178 | 109 | 5-1 | 1-2 | 1W |
Virginia Tech
|
6 | 3 | 308 | 215 | 93 | 3-1 | 3-2 | 1L |
|
North Carolina
|
5 | 4 | 244 | 205 | 39 | 1-3 | 4-1 | 1W |
Boston College
|
4 | 5 | 197 | 243 | -46 | 3-2 | 1-3 | 2L |
Florida State
|
4 | 5 | 276 | 255 | 21 | 3-2 | 1-3 | 1W |
NC State
|
4 | 5 | 260 | 248 | 12 | 4-2 | 0-3 | 1L |
Stanford
|
4 | 5 | 183 | 336 | -153 | 4-1 | 0-4 | 1L |
Virginia
|
4 | 5 | 233 | 208 | 25 | 4-2 | 0-3 | 3L |
California
|
3 | 6 | 197 | 284 | -87 | 2-3 | 1-3 | 3L |
Syracuse
|
4 | 5 | 264 | 229 | 35 | 2-3 | 2-2 | 1L |
Georgia Tech
|
2 | 7 | 215 | 290 | -75 | 2-4 | 0-3 | 4L |
Florida State
Pittsburgh
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