Northwestern vs Penn State Prediction, Picks & Odds | 11 Oct 2025
College Football Betting Preview: Northwestern vs Penn State
Northwestern square off against Penn State in this NCAAF Week 7 matchup at Beaver Stadium, with kickoff scheduled for 15:30 on Saturday, October 11. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.
Penn State Look Set for a Big Win
Let’s go for Penn State at a generous -22.5 on the spread. We really like this pick and are able to get odds of -105 that they beat Northwestern by a big margin.
Taking our side against the spread? Take a moment to read our detailed BetMGM review, then take advantage of the new promo code before you jump in.
41-13 Triumph for Penn State in Last H2H
Northwestern Wildcats have won their previous two games. The latest was a 42-7 home triumph at Northwestern Medicine Field at Martin Stadium against Louisiana-Monroe Warhawks.
Penn State Nittany Lions have suffered defeat in their last two games. Most recently, a 42-37 scoreline occurred on the road at Rose Bowl against UCLA Bruins.
Head-to-Head Statistics
Penn State won the most recent matchup between these teams. A 41-13 victory was registered against Northwestern at Ryan Field.
Quarterbacks
Preston Stone
Drew Allar
Northwestern vs Penn State Prediction & Picks
Head into Northwestern vs Penn State with expert betting insights, including our main match prediction, expected scoreline, key player prop picks and a thoughtfully built bet builder.
Game Prediction
We strongly fancy the chances of Penn State beating the underdogs handsomely in this college football matchup. That is why we’re betting them at -22.5 on the spread at -105.
Knowing which players are injured gives us a valuable edge when making college football predictions. After reviewing the form guide, we turn to the latest stats to shape our picks.
Key Northwestern vs Penn State stats:
Penn State -22.5 Probability
If you go by the top betting apps, there’s a 51.3% chance that our pick is settled as a winner. In the opinion of our cappers, there’s actually a probability of success closer to 60%. It is therefore regarded as a value bet.
If you want bigger odds, then you can move the line by selling points. Choose how many points to sell until you are happy with the juice available.
Before placing your next bet, explore our complete guide to the best betting offers, promotions and welcome bonuses today.
Best Bet
Penn State -22.5 @ -105
Player Prop Picks
You can place a bet on Preston Stone (Northwestern) at -114 to record fewer than 127.5 passing yards. If you agree with our verdict that the line is too high, this QB Passing Yards wager is worth backing.
You can back Griffin Wilde (Northwestern) at -114 to finish with fewer than 40.5 receiving yards. There’s no reason to doubt our instinct, so we’ll bet on him falling short of the Player Receiving Yards line.
Same Game Parlay Picks
We’ve got a same game parlay with three options: Penn State -22.5, Over 47.5 points and Preston Stone (Northwestern) to have Under 127.5 passing yards.
There are many options when you place a same game parlay. You can go through the football lines and identify your favorite outcomes before combining the odds on the bet slip. Personalised betting doesn’t come any better.
Correct Score Prediction
10
-
41
Penn State
There are lots of different betting angles including the chance to bet on the Lions on the correct score lines. For example, a 41-10 win in their favor is available at huge odds.
Northwestern vs Penn State Odds
The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.
Books Running Scared of Penn State Win
Penn State are strong -1667 favorites to win this college game according to the Moneyline betting odds. The sportsbooks give them a 94% chance of claiming victory. Northwestern are the underdogs at +900 and they’re regarded as least likely to win.
20.5 is the spread and 46.5 is the total points line. The Totals offers football bettors an alternative way of getting involved. Those expecting a low total can back Under 46.5 at -110.
You can find a wide range of team props and game lines for every college football matchup, with the best sportsbooks creating lots of different options. Explore the pre-game and in-game selections before placing your wagers.
Kaytron Allen Favorite to Score First Touchdown
The First Touchdown Scorer favorite is Kaytron Allen at +370. Similar odds can be found if you’re interested in this player to register the final TD.
Touchdown
Receiving Yards
Rushing Yards
Passing Yards
Micro Betting
Instead of focusing on the overall outcome, some bettors prefer to look at the college football micro betting lines. As the name suggests, it means placing short-term in-game wagers and this might include the Next Play or Next Drive Result.
Penn State Have Eight Wins in Their Last Ten Home Games
Penn State have a 8-2 record in their last 10 home games, posting 33.40 points per contest while yielding 10.80.
Northwestern own a 4-6 mark in their past 10 games away from home, averaging 18.30 points scored and 27.50 points allowed.
In their most recent matchup at Beaver Stadium, Penn State got the better of Northwestern 17-7.
| Last 10 Games | W-L | P | PF | PA | O47.5 | U47.5 | |
|---|---|---|---|---|---|---|---|
 Penn State Home Stats |
8-2 | 44.20 | 33.40 | 10.80 | 5 | 5 | |
 Northwestern Away Stats |
4-6 | 45.80 | 18.30 | 27.50 | 4 | 6 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O47.5 = Games Over 47.5 Points
- U47.5 = Games Under 47.5 Points
Last 5 & H2H
Latest regular season and playoff games stats.
Northwestern Wildcats Stats
Penn State Nittany Lions Stats
- 4 wins and 6 defeats in the last 10 games
- 4 wins and 6 defeats in the last 10 games on the road
- +22.5 Betting Line: Have covered the spread in 7 of the last 10 games
- +22.5 Betting Line on the Road: Have covered the spread in 7 of the last 10 games on the road
- -22.5 Betting Line: Have covered the spread in 5 of the last 10 games
- -22.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games
- Game Totals: An average of 46.30 pts in the previous 10 games
- Game Totals on the Road: An average of 45.80 pts in the previous 10 games on the road
- Over 47.5: Covered in 6 of the previous 10 games
- Over 47.5 on the Road: Covered in 4 of the previous 10 games on the road
- Team Totals: Have scored an average of 19.90 pts and allowed 26.40 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 18.30 pts and allowed 27.50 pts in the last 10 games on the road
- Game Totals: An average of 55.90 pts in the previous 10 games
- Game Totals at Home: An average of 46.50 pts in the previous 10 home games
- Over 47.5: Covered in 8 of the previous 10 games
- Over 47.5 at Home: Covered in 6 of the previous 10 home games
- Team Totals: Have scored an average of 36.70 pts and allowed 19.20 pts in the last 10 games
- Team Totals at Home: Have scored an average of 33.70 pts and allowed 12.80 pts in the last 10 home games
NCAAF Standings Select Season
| Big Ten | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Indiana
|
10 | 0 | 445 | 121 | 324 | 6-0 | 4-0 | 10W |
Ohio State
|
9 | 0 | 327 | 65 | 262 | 5-0 | 4-0 | 9W |
Oregon
|
8 | 1 | 348 | 124 | 224 | 4-1 | 4-0 | 3W |
Michigan
|
7 | 2 | 253 | 155 | 98 | 5-0 | 2-2 | 3W |
USC
|
7 | 2 | 356 | 196 | 160 | 5-0 | 2-2 | 2W |
Nebraska
|
7 | 3 | 325 | 199 | 126 | 4-2 | 3-1 | 1W |
Minnesota
|
6 | 3 | 214 | 194 | 20 | 6-0 | 0-3 | 1W |
Iowa
|
6 | 3 | 266 | 123 | 143 | 4-2 | 2-1 | 1L |
Washington
|
6 | 3 | 294 | 180 | 114 | 4-1 | 2-2 | 1L |
Illinois
|
6 | 3 | 298 | 233 | 65 | 4-1 | 2-2 | 1W |
|
Northwestern
|
5 | 4 | 197 | 172 | 25 | 4-1 | 1-3 | 2L |
Rutgers
|
5 | 5 | 299 | 300 | -1 | 4-2 | 1-3 | 1W |
Maryland
|
4 | 5 | 228 | 211 | 17 | 3-3 | 1-2 | 5L |
UCLA
|
3 | 6 | 184 | 276 | -92 | 2-3 | 1-3 | 2L |
Wisconsin
|
3 | 6 | 113 | 201 | -88 | 3-3 | 0-3 | 1W |
Michigan State
|
3 | 6 | 230 | 283 | -53 | 3-2 | 0-4 | 6L |
|
Penn State
|
3 | 6 | 276 | 201 | 75 | 3-3 | 0-3 | 6L |
Purdue
|
2 | 8 | 209 | 277 | -68 | 2-4 | 0-4 | 8L |
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